Structures of the tailed bacteriophages that infect Gram-positive bacteria.

Abstract:

:Productive virus infection depends upon delivery of viral genomic material into the host cell cytoplasm. The tails of bacteriophages recognize host cells and mediate host cell wall and membrane penetration. Recent cryo-electron microscopy studies have revealed near atomic-resolutions structures of the entire or almost entire bacteriophage particles of model systems including phi29, P22, P68, and T4. These structures allow comparisons between not only different states of the same phage but also between distantly related phages. In this review, we summarize the findings from recent structural studies of the bacteriophages that target Gram-positive bacteria, for a better understanding of the interactions between host cells and bacteriophages.

journal_name

Curr Opin Virol

authors

Huang L,Xiang Y

doi

10.1016/j.coviro.2020.09.002

subject

Has Abstract

pub_date

2020-12-01 00:00:00

pages

65-74

eissn

1879-6257

issn

1879-6265

pii

S1879-6257(20)30090-0

journal_volume

45

pub_type

杂志文章,评审
  • The search for meaning in virus discovery.

    abstract::The rate of new virus discovery is increasing dramatically with improvements in sequencing and other molecular diagnostic platforms, and investments in sample collection and analysis. However, progress has been more limited in identification and implication of infectious agents that pose threats to human health and we...

    journal_title:Current opinion in virology

    pub_type: 杂志文章,评审

    doi:10.1016/j.coviro.2011.10.010

    authors: Daszak P,Lipkin WI

    更新日期:2011-12-01 00:00:00

  • Impacts of poultry vaccination on viruses of wild bird.

    abstract::Spillover of viruses from farmed poultry into wild birds is a relatively new area of study at the livestock-wildlife interface. These transmission events can threaten the health of wild birds. There is growing evidence of transmission of vaccine viruses from poultry to wild birds, including attenuated vaccine strains ...

    journal_title:Current opinion in virology

    pub_type: 杂志文章,评审

    doi:10.1016/j.coviro.2016.06.007

    authors: Devlin JM,Vaz PK,Coppo MJ,Browning GF

    更新日期:2016-08-01 00:00:00

  • The depths of virus exaptation.

    abstract::Viruses are ubiquitous parasites of cellular life forms and the most abundant biological entities on earth. The relationships between viruses and their hosts involve the continuous arms race but are by no account limited to it. Growing evidence shows that, in the course of evolution, viruses and their components are r...

    journal_title:Current opinion in virology

    pub_type: 杂志文章,评审

    doi:10.1016/j.coviro.2018.07.011

    authors: Koonin EV,Krupovic M

    更新日期:2018-08-01 00:00:00

  • Functions of DNA damage machinery in the innate immune response to DNA virus infection.

    abstract::DNA is potently immunostimulatory, and self-DNA is packaged in the nucleus or mitochondria allowing it to remain silent to cell-intrinsic sensors. However, damaged or mislocalised self-DNA is sensed by our innate immune systems, resulting in the production of type I interferons (IFNI), chemokines and inflammatory cyto...

    journal_title:Current opinion in virology

    pub_type: 杂志文章,评审

    doi:10.1016/j.coviro.2015.08.001

    authors: Trigg BJ,Ferguson BJ

    更新日期:2015-12-01 00:00:00

  • Biochemical principles and inhibitors to interfere with viral capping pathways.

    abstract::Messenger RNAs are decorated by a cap structure, which is essential for their translation into proteins. Many viruses have developed strategies in order to cap their mRNAs. The cap is either synthetized by a subset of viral or cellular enzymes, or stolen from capped cellular mRNAs by viral endonucleases ('cap-snatchin...

    journal_title:Current opinion in virology

    pub_type: 杂志文章,评审

    doi:10.1016/j.coviro.2017.04.003

    authors: Decroly E,Canard B

    更新日期:2017-06-01 00:00:00

  • Structural similarities in DNA packaging and delivery apparatuses in Herpesvirus and dsDNA bacteriophages.

    abstract::Structural information can inform our understanding of virus origins and evolution. The herpesviruses and tailed bacteriophages constitute two large families of dsDNA viruses which infect vertebrates and prokaryotes respectively. A relationship between these disparate groups was initially suggested by similarities in ...

    journal_title:Current opinion in virology

    pub_type: 杂志文章,评审

    doi:10.1016/j.coviro.2014.02.003

    authors: Rixon FJ,Schmid MF

    更新日期:2014-04-01 00:00:00

  • Virus disinfection mechanisms: the role of virus composition, structure, and function.

    abstract::Drinking waters are treated for enteric virus via a number of disinfection techniques including chemical oxidants, irradiation, and heat, however the inactivation mechanisms during disinfection remain elusive. Owing to the fact that a number of significant waterborne virus strains are not readily culturable in vitro a...

    journal_title:Current opinion in virology

    pub_type: 杂志文章,评审

    doi:10.1016/j.coviro.2011.11.003

    authors: Wigginton KR,Kohn T

    更新日期:2012-02-01 00:00:00

  • Vertical transmission of positive-sense single-stranded RNA viruses in plants as a model for arboviral induced teratogenesis.

    abstract::Teratogenic viruses have increased public health importance with the emergence of Zika virus and a recent decline in rubella virus vaccination. Of the seven viruses known to cause birth defects in humans, three are mosquito-borne pathogens. Ethical oversight, compliance, rising costs, and the need for specialized trai...

    journal_title:Current opinion in virology

    pub_type: 杂志文章,评审

    doi:10.1016/j.coviro.2017.11.010

    authors: Barr KL

    更新日期:2017-12-01 00:00:00

  • Modulation of HIV reservoirs by host HLA: bridging the gap between vaccine and cure.

    abstract::Latent HIV reservoirs are the greatest challenge facing an HIV cure. Here, we review recent evidence supporting an important role for the host immune response, in particular HLA class I-restricted CD8+ T lymphocytes, in modulating HIV reservoirs during natural infection. These observations indicate that factors govern...

    journal_title:Current opinion in virology

    pub_type: 杂志文章,评审

    doi:10.1016/j.coviro.2012.08.003

    authors: Brumme ZL,Chopera DR,Brockman MA

    更新日期:2012-10-01 00:00:00

  • Licensure of vaccines using the Animal Rule.

    abstract::A number of new vaccines are being developed against microbial pathogens that might be used as bioweapons. For some of these vaccines, because of the lack of endemic disease and the lethal nature of the disease, human efficacy studies would not be ethical or feasible to conduct. In such cases, a regulation, known as t...

    journal_title:Current opinion in virology

    pub_type: 杂志文章

    doi:10.1016/j.coviro.2012.01.004

    authors: Burns DL

    更新日期:2012-06-01 00:00:00

  • Immune-surveillance through exhausted effector T-cells.

    abstract::Pathogens such as the human immunodeficiency virus (HIV), the hepatitis B and C virus (HBV, HCV) and certain strains of the rodent lymphocytic choriomeningitis virus (LCMV) establish a state of persisting viral replication. This occurs besides strong adoptive immune responses and the induction of large numbers of acti...

    journal_title:Current opinion in virology

    pub_type: 杂志文章,评审

    doi:10.1016/j.coviro.2016.01.002

    authors: Zehn D,Utzschneider DT,Thimme R

    更新日期:2016-02-01 00:00:00

  • Roseoloviruses: unmet needs and research priorities: perspective.

    abstract::The human roseoloviruses, human herpesviruses 6A (HHV-6A), HHV-6B, and HHV-7, are highly prevalent viruses that typically cause fever/rash illnesses such as roseola during early life primary infections. They also cause significant neurologic disease and complications following stem cell and solid organ transplantation...

    journal_title:Current opinion in virology

    pub_type: 杂志文章,评审

    doi:10.1016/j.coviro.2014.10.005

    authors: Caserta MT,Krug LT,Pellett PE

    更新日期:2014-12-01 00:00:00

  • Broadly neutralizing antibodies against influenza virus and prospects for universal therapies.

    abstract::Vaccines are the gold standard for the control and prevention of infectious diseases, but a number of important human diseases remain challenging targets for vaccine development. An influenza vaccine that confers broad spectrum, long-term protection remains elusive. Several broadly neutralizing antibodies have been id...

    journal_title:Current opinion in virology

    pub_type: 杂志文章,评审

    doi:10.1016/j.coviro.2012.02.005

    authors: Ekiert DC,Wilson IA

    更新日期:2012-04-01 00:00:00

  • Latent papillomavirus infections and their regulation.

    abstract::Model systems show that papillomavirus DNA can persist after lesion-regression, and be maintained in a subset of epithelial basal cells. These are very likely long-lived 'stem-cells' or 'stem-like cells', with latency arising via at least two distinct mechanisms. The first involves low-titre virus infection and the re...

    journal_title:Current opinion in virology

    pub_type: 杂志文章,评审

    doi:10.1016/j.coviro.2013.06.003

    authors: Doorbar J

    更新日期:2013-08-01 00:00:00

  • Using the ferret model to study morbillivirus entry, spread, transmission and cross-species infection.

    abstract::Canine distemper virus (CDV) is an animal morbillivirus with a worldwide circulation that infects carnivores, including domestic dogs and an assortment of wildlife hosts. The development of reverse genetics systems for wild-type strains of CDV and the use of the resulting recombinant (r) viruses to infect ferrets by a...

    journal_title:Current opinion in virology

    pub_type: 杂志文章,评审

    doi:10.1016/j.coviro.2013.11.001

    authors: Ludlow M,Rennick LJ,Nambulli S,de Swart RL,Duprex WP

    更新日期:2014-02-01 00:00:00

  • Human papillomavirus infection and induction of neoplasia: a matter of fitness.

    abstract::The aetiologic association between infection with certain human papillomavirus (HPV) types, high-grade squamous neoplasia, and cancer at different epithelial sites is well established. In this review we briefly discuss recent breakthroughs in the regulation of squamous epithelia in homeostasis and disease, and provide...

    journal_title:Current opinion in virology

    pub_type: 杂志文章,评审

    doi:10.1016/j.coviro.2016.08.011

    authors: Kranjec C,Doorbar J

    更新日期:2016-10-01 00:00:00

  • UPR signaling at the nexus of plant viral, bacterial, and fungal defenses.

    abstract::In recent years there have been significant advances in our understanding of the ER stress responses in plants that are associated with virus infection, as well as bacterial and fungal diseases. In plants, ER stress induced by virus infection includes several signaling pathways that include the unfolded protein respon...

    journal_title:Current opinion in virology

    pub_type: 杂志文章,评审

    doi:10.1016/j.coviro.2020.11.001

    authors: Verchot J,Pajerowska-Mukhtar KM

    更新日期:2020-12-21 00:00:00

  • Assessment of antiviral therapeutics in animal models of Lassa fever.

    abstract::Lassa virus (LASV) is an emerging zoonotic virus endemic in West Africa that can cause severe haemorrhagic Lassa fever (LF) in humans. LF recently gained international attention as a prominent infectious disease, leading to increasingly severe outbreaks in Nigeria over the past three years. Morbidity and mortality ass...

    journal_title:Current opinion in virology

    pub_type: 杂志文章,评审

    doi:10.1016/j.coviro.2019.06.010

    authors: Warner BM,Siragam V,Stein DR

    更新日期:2019-08-01 00:00:00

  • The role of CD27 in anti-viral T-cell immunity.

    abstract::CD27 is a co-stimulatory immune-checkpoint receptor, constitutively expressed on a broad range of T-cells (αβ and γδ), NK-cells and B-cells. Ligation of CD27 with CD70 results in potent co-stimulatory effects. In mice, co-stimulation of CD8+ T-cells through CD27 promotes immune activation and enhances primary, seconda...

    journal_title:Current opinion in virology

    pub_type: 杂志文章,评审

    doi:10.1016/j.coviro.2016.12.001

    authors: Grant EJ,Nüssing S,Sant S,Clemens EB,Kedzierska K

    更新日期:2017-02-01 00:00:00

  • Disruption of host antiviral resistances by gammaherpesvirus tegument proteins with homology to the FGARAT purine biosynthesis enzyme.

    abstract::All known gammaherpesviruses encode at least one conserved tegument protein that contains sequence homology to the cellular purine biosynthesis enzyme: phosphoribosylformylglycineamide amidotransferase (FGARAT, or PFAS). While no enzymatic activity have been found on these viral FGARAT-homology proteins (vFGARAT), the...

    journal_title:Current opinion in virology

    pub_type: 杂志文章,评审

    doi:10.1016/j.coviro.2015.07.008

    authors: Tsai K,Messick TE,Lieberman PM

    更新日期:2015-10-01 00:00:00

  • Norovirus mechanisms of immune antagonism.

    abstract::Noroviruses are a leading cause of gastroenteritis outbreaks globally. Several lines of evidence indicate that noroviruses can antagonize or evade host immune responses, including the absence of long-lasting immunity elicited during a primary norovirus exposure and the ability of noroviruses to establish prolonged inf...

    journal_title:Current opinion in virology

    pub_type: 杂志文章,评审

    doi:10.1016/j.coviro.2015.11.005

    authors: Roth AN,Karst SM

    更新日期:2016-02-01 00:00:00

  • Cytotoxicity in Epstein Barr virus specific immune control.

    abstract::Epstein Barr virus (EBV) is the most common human tumor virus, persistently infecting more than 95% of the human adult population and readily transforming human B cell in culture. Fortunately, only a small minority of EBV carriers develops virus associated malignancies. The majority controls persistent EBV infection w...

    journal_title:Current opinion in virology

    pub_type: 杂志文章,评审

    doi:10.1016/j.coviro.2020.07.011

    authors: Münz C

    更新日期:2020-08-06 00:00:00

  • Mapping the evolutionary trajectories of morbilliviruses: what, where and whither.

    abstract::Morbilliviruses are pathogens of humans and other animals. Live attenuated morbillivirus vaccines have been used to end endemic transmission of measles virus (MV) in many parts of the developed world and to eradicate rinderpest virus. Entry is mediated by two different receptors which govern virus lymphotropism and ep...

    journal_title:Current opinion in virology

    pub_type: 杂志文章,评审

    doi:10.1016/j.coviro.2016.01.019

    authors: Nambulli S,Sharp CR,Acciardo AS,Drexler JF,Duprex WP

    更新日期:2016-02-01 00:00:00

  • Antiviral drugs specific for coronaviruses in preclinical development.

    abstract::Coronaviruses are positive stranded RNA viruses that cause respiratory, enteric and central nervous system diseases in many species, including humans. Until recently, the relatively low burden of disease in humans caused by few of these viruses impeded the development of coronavirus specific therapeutics. However, the...

    journal_title:Current opinion in virology

    pub_type: 杂志文章,评审

    doi:10.1016/j.coviro.2014.06.002

    authors: Adedeji AO,Sarafianos SG

    更新日期:2014-10-01 00:00:00

  • Virus entry: old viruses, new receptors.

    abstract::The long-sought entry receptors for rubella, sindbis and respiratory syncytial viruses (RV, SV and RSV), together with the missing measles virus (MV) receptor for infection of epithelial cells, were identified in 2011. These have been major developments in the field of virus entry. In addition, 2011 was rich in new in...

    journal_title:Current opinion in virology

    pub_type: 杂志文章,评审

    doi:10.1016/j.coviro.2011.12.005

    authors: Backovic M,Rey FA

    更新日期:2012-02-01 00:00:00

  • Rhabdoviruses as vectors for vaccines and therapeutics.

    abstract::Appropriate choice of vaccine vector is crucial for effective vaccine development. Rhabdoviral vectors, such as rabies virus and vesicular stomatitis virus, have been used in a variety of vaccine strategies. These viruses have small, easily manipulated genomes that can stably express foreign glycoproteins due to a wel...

    journal_title:Current opinion in virology

    pub_type: 杂志文章,评审

    doi:10.1016/j.coviro.2020.09.003

    authors: Scher G,Schnell MJ

    更新日期:2020-10-01 00:00:00

  • Evolution of plant-virus interactions: host range and virus emergence.

    abstract::Changes in host range are central to virus emergence. Host range, together with its evolution, is determined by virus intrinsic factors, such as genetic traits determining its fitness in different hosts. Experimental analyses have shown the relevance in host range evolution of across-host fitness trade-offs. Host rang...

    journal_title:Current opinion in virology

    pub_type: 杂志文章,评审

    doi:10.1016/j.coviro.2018.12.003

    authors: McLeish MJ,Fraile A,García-Arenal F

    更新日期:2019-02-01 00:00:00

  • The role of viruses in biological invasions: friend or foe?

    abstract::Biological invasions occur when plants, animals, or microbes are introduced to a new geographic region, then spread and have negative consequences for the local ecosystem. Across both plant and animal hosts, viruses can play diverse roles in biological invasions. First, viruses can either decrease or increase the impa...

    journal_title:Current opinion in virology

    pub_type: 杂志文章

    doi:10.1016/j.coviro.2011.05.018

    authors: Rúa MA,Pollina EC,Power AG,Mitchell CE

    更新日期:2011-07-01 00:00:00

  • Immunomonitoring of human responses to the rVSV-ZEBOV Ebola vaccine.

    abstract::The rVSV-ZEBOV vaccine is currently the only Ebola vaccine with demonstrated clinical efficacy in a ring-vaccination clinical trial. It has been shown to be reactogenic but immunogenic and safe in several Phase I clinical studies. However, its mechanisms of protection are unknown and available immunogenicity data are ...

    journal_title:Current opinion in virology

    pub_type: 杂志文章,评审

    doi:10.1016/j.coviro.2017.03.008

    authors: Medaglini D,Siegrist CA

    更新日期:2017-04-01 00:00:00

  • Reverse genetics approaches for the development of bunyavirus vaccines.

    abstract::The Bunyavirales order is the largest group of RNA viruses, which includes important human and animal pathogens, that cause serious diseases. Licensed vaccines are often not available for many of these pathogens. The establishment of bunyavirus reverse genetics systems has facilitated the generation of recombinant inf...

    journal_title:Current opinion in virology

    pub_type: 杂志文章,评审

    doi:10.1016/j.coviro.2020.05.004

    authors: Tercero B,Makino S

    更新日期:2020-10-01 00:00:00