A Prognostic Model to Predict Recovery of COVID-19 Patients Based on Longitudinal Laboratory Findings.

abstract：:Rotavirus (RV) is a major foodborne pathogen. For RV prevention and control, it is a key to uncover the interaction mechanism between virus and its receptors. However, it is hard to specially purify the viral receptors, including histo-blood group antigens (HBGAs). Previously, the protruding domain protein (P protein)...

journal_title：Virologica Sinica

authors： Liu D,Geng H,Zhang Z,Xing Y,Yang D,Liu Z,Wang D

更新日期：2020-02-01 00:00:00

abstract：:An emerging mosquito-borne arbovirus named Zika virus (ZIKV), of the family Flaviviridae and genus Flavivirus, is becoming a global health threat. ZIKV infection was long neglected due to its sporadic nature and mild symptoms. However, recently, with its rapid spread from Asia to the Americas, affecting more than 30 c...

journal_title：Virologica Sinica

authors： Wang Z,Wang P,An J

更新日期：2016-04-01 00:00:00

abstract：:Human endogenous retrovirus W env (HERV-W env) plays a critical role in many neuropsychological diseases such as schizophrenia and multiple sclerosis (MS). These diseases are accompanied by immunological reactions in the central nervous system (CNS). Microglia are important immunocytes in brain inflammation that can p...

journal_title：Virologica Sinica

authors： Xiao R,Li S,Cao Q,Wang X,Yan Q,Tu X,Zhu Y,Zhu F

更新日期：2017-06-01 00:00:00

abstract：:The dengue virus (DENV) is a vital global public health issue. The 2014 dengue epidemic in Guangzhou, China, caused approximately 40,000 cases of infection and five deaths. We carried out a comprehensive investigation aimed at identifying the transmission sources in this dengue epidemic. To analyze the phylogenetics o...

journal_title：Virologica Sinica

authors： Li G,Pan P,He Q,Kong X,Wu K,Zhang W,Liu Y,Huang H,Liu J,Zhang Z,Wu,Lai X,Liu X,Wu J

更新日期：2017-02-01 00:00:00

abstract：:Laos is the only landlocked country in Southeast Asia and borders Thailand, Myanmar and Cambodia, the three countries in this region that have been hardest hit by human immunodeficiency virus (HIV). Laos has been regarded as a low-HIV-prevalence country for decades. To understand the status of HIV in Laos in recent ye...

journal_title：Virologica Sinica

authors： Chen X,Ye M,Wang Y,Zhang C,Zheng YT

更新日期：2020-10-01 00:00:00

abstract：:The aim of the work is the comparison of the epidemiology of influenza and acute respiratory virus infections (ARVI) in the Republic of Kazakhstan with the corresponding influenza epidemic in Russia induced by influenza pandemic virus A/California/07/2009 in 2009. Data on influenza and ARVI from the Republic of Kazakh...

journal_title：Virologica Sinica

authors： Karpova LS,Popovtseva NM,Stolyarova TP,Stolyarov KA,Mamadaliyev SM,Khairullin BM,Sandybayev NT,Kydyrbayev ZhK,Orynbayev MB,Ospanov KS,Baiserkin BS,Boibosinov EU

更新日期：2011-10-01 00:00:00

abstract：:Ebola virus (EBOV) and Marburg virus (MARV) are causative agents of severe hemorrhagic fever with high mortality rates in humans and non-human primates and there is currently no licensed vaccine or therapeutics. To date, there is no specific laboratory diagnostic test in China, while there is a national need to provid...

journal_title：Virologica Sinica

authors： Huang Y,Wei H,Wang Y,Shi Z,Raoul H,Yuan Z

更新日期：2012-10-01 00:00:00

abstract：:In this paper, in vitro anti-influenza virus activities of sulfated polysaccharide fractions from Gracilaria lemaneiformis were investigated. Cytotoxicities and antiviral activities of Gracilaria lemaneiformis polysaccharides (PGL), Gracilaria lemaneiformis polysaccharide fraction-1 (GL-1), Gracilaria lemaneiformis po...

journal_title：Virologica Sinica

authors： Chen MZ,Xie HG,Yang LW,Liao ZH,Yu J

更新日期：2010-10-01 00:00:00

abstract：:Circular RNAs (circRNAs) belong to a class of non-coding RNAs with diverse biological functions. However, little is known about their roles in case of pseudorabies virus (PrV) infection. Here, we analyzed the expression profile of host circRNAs from a virulent PrV type II strain DX (PrV-DX) infected and an attenuated ...

journal_title：Virologica Sinica

authors： Li H,Tang W,Jin Y,Dong W,Yan Y,Zhou J

更新日期：2020-07-02 00:00:00

abstract：:The papain-like protease (PL(pro)) of Middle-East respiratory syndrome coronavirus (MERS-CoV) has proteolytic, deubiquitinating, and deISGylating activities. The latter two are involved in the suppression of the antiviral innate immune response of the host cell. To contribute to an understanding of this process, we pr...

journal_title：Virologica Sinica

authors： Lei J,Hilgenfeld R

更新日期：2016-08-01 00:00:00

abstract：:H9N2 subtype avian influenza virus (AIV) is an influenza A virus that is widely spread throughout Asia, where it jeopardizes the poultry industry and provides genetic material for emerging human pathogens. To better understand the epidemicity and genetics of H9 subtype AIVs, we conducted active surveillance in live po...

journal_title：Virologica Sinica

authors： Hu Z,Peng F,Xiong Z,Zhang W,Li T,Shi Y,Xie J,Jin X,Huang J,Xiao H,Bi D,Song N,Li Z

更新日期：2020-09-14 00:00:00

abstract：:Respiratory syncytial virus (RSV) is the key underlying cause of acute lower respiratory tract infection in infants; however, no licensed vaccine against RSV infection is currently available. This study was undertaken to assess the preventive effect of vaccine on RSV infection. In this metaanalysis, 1,792 published ra...

journal_title：Virologica Sinica

authors： Zhu T,Zhang C,Yu L,Chen J,Qiu H,Lyu W,Huang S

更新日期：2015-10-01 00:00:00

abstract：:Severe fever with thrombocytopenia syndrome virus (SFTSV), the causative agent of a febrile human disease, was first identified from central and eastern provinces in China, and later in Japan and South Korea. Hubei Province is one of the major SFTS epidemic areas in the central part of China. This study reported the i...

journal_title：Virologica Sinica

authors： Wu X,Li M,Zhang Y,Liang B,Shi J,Fang Y,Su Z,Li M,Zhang W,Xu L,Wang J,Wu Q,Tang S,Wang H,Zhang T,Peng C,Zheng X,Deng F,Shen S

更新日期：2020-09-22 00:00:00

abstract：:Ebola virus (EBOV) causes severe hemorrhagic fever in humans and non-human primates with high rates of fatality. Glycoprotein (GP) is the only envelope protein of EBOV, which may play a critical role in virus attachment and entry as well as stimulating host protective immune responses. However, the lack of expression ...

journal_title：Virologica Sinica

authors： Zai J,Yi Y,Xia H,Zhang B,Yuan Z

更新日期：2016-12-01 00:00:00

abstract：:Recreational waters contaminated with human fecal pollution are a public health concern, and ensuring the safety of recreational waters for public use is a priority of both the Environmental Protection Agency (EPA) and the Centers for Disease Control and Prevention (CDC). Current recreational water standards rely on f...

journal_title：Virologica Sinica

authors： Updyke EA,Wang Z,Sun S,Connell C,Kirs M,Wong M,Lu Y

更新日期：2015-10-01 00:00:00

abstract：:The protein HTRP (human transcription regulator protein) is encoded by the differential gene htrp and induced by Herpes simplex virus type 1 (HSV-1) infection in KMB-17 cells. HTRP was found to interact with SAP30 (mSin3A Association Protein), one of the components of co-repressor complex mSin3A, which is part of the ...

journal_title：Virologica Sinica

authors： Chen J,Li YM,Li JF,Liu LD,Liao Y,Na RX,Wang JJ,Wang LC,Li QH

更新日期：2010-12-01 00:00:00

abstract：:A 62-year-old man had chronic hepatitis B virus (HBV) infection and was diagnosed with liver cirrhosis. At the time of diagnosis the patient's virologic markers were positive for hepatitis B surface antigen (HBsAg), antibody to hepatitis B e antigen (anti-HBe) and antibody to hepatitis B core antigen (anti-HBc), while...

journal_title：Virologica Sinica

authors： Wu C,Shi H,Wang Y,Lu M,Xu Y,Chen X

更新日期：2012-12-01 00:00:00

abstract：:Conventional influenza vaccines are based on predicting the circulating viruses year by year, conferring limited effectiveness since the antigenicity of vaccine strains does not always match the circulating viruses. This necessitates development of universal influenza vaccines that provide broader and lasting protecti...

journal_title：Virologica Sinica

authors： Du R,Cui Q,Rong L

更新日期：2020-09-01 00:00:00

abstract：:Middle East Respiratory Syndrome Coronavirus (MERS-CoV) is a zoonotic pathogen capable of causing severe respiratory disease in humans. Although dromedary camels are considered as a major reservoir host, the MERS-CoV infection dynamics in camels are not fully understood. Through surveillance in Pakistan, nasal (n = 77...

journal_title：Virologica Sinica

authors： Zohaib A,Saqib M,Athar MA,Chen J,Sial AU,Khan S,Taj Z,Sadia H,Tahir U,Tayyab MH,Qureshi MA,Mansoor MK,Naeem MA,Hu BJ,Khan BA,Ujjan ID,Li B,Zhang W,Luo Y,Zhu Y,Waruhiu C,Khan I,Yang XL,Sajid MS,Corman VM,

更新日期：2018-10-01 00:00:00

abstract：:Banana bunchy top virus (BBTV) poses a serious danger to banana crops worldwide. BBTV-encoded protein B4 is a determinant of pathogenicity. However, the relevant molecular mechanisms underlying its effects remain unknown. In this study, we found that a functional peptide could be liberated from protein B4, likely via ...

journal_title：Virologica Sinica

authors： Zhuang J,Lin W,Coates CJ,Shang P,Wei T,Wu Z,Xie L

更新日期：2019-06-01 00:00:00

abstract：:Histone deacetylase (HDAC) inhibitors show clinical promise for the treatment of cancers, including hepatocellular carcinoma (HCC). In this study, we investigated the effect of HDAC inhibitor treatment on hepatitis C virus (HCV) replication in Huh7 human liver cells and in a mouse model of HCV infection. Viral replica...

journal_title：Virologica Sinica

authors： Zhou Y,Wang Q,Yang Q,Tang J,Xu C,Gai D,Chen X,Chen J

更新日期：2018-10-01 00:00:00

abstract：:Porcine pegivirus (PPgV) is a member of the Pegivirus genus in the Flaviviridae family. PPgV is an emerging virus that has been discovered in swine herds in Germany, the United States, China, Poland, Italy, and the United Kingdom, indicating a wide geographical distribution. In this retrospective study, 339 pig serum ...

journal_title：Virologica Sinica

authors： Xie Y,Wang X,Feng J,Wei L,Li G,Si G,Chen Y,Yan H,He D

更新日期：2020-07-08 00:00:00

abstract：:Ion channels are membrane proteins that are found in a number of viruses and which are of crucial physiological importance in the viral life cycle. They have one common feature in that their action mode involves a change of electrochemical or proton gradient across the bilayer lipid membrane which modulates viral or c...

journal_title：Virologica Sinica

authors： Liang X,Li ZY

更新日期：2010-08-01 00:00:00

abstract：:Southern rice black-streaked dwarf virus (SRBSDV) is a novel Fijivirus prevalent in rice in southern and central China, and northern Vietnam. Its genome has 10 segments of double-stranded RNA named S1 to S10 according to their size. An isolate of SRBSDV, JNi4, was obtained from naturally infected maize plants from Ji'...

journal_title：Virologica Sinica

authors： Yin X,Xu FF,Zheng FQ,Li XD,Liu BS,Zhang CQ

更新日期：2011-02-01 00:00:00

abstract：:Effective oral infection is set off by interaction of a group of conserved per os infectivity factors (PIFs) with larval midgut columnar epithelial cells. We constructed pseudotyped viruses by substituting pif1, pif2 or pif3 genes of Helicoverpa armigera nucleopolyhedrovirus (HearNPV) with their homologs from Mamestra...

journal_title：Virologica Sinica

authors： Makalliwa GA,Wang X,Zhang H,Zhang N,Chen C,Li J,Deng F,Wang H,Wang M,Hu Z

更新日期：2018-04-01 00:00:00

abstract：:Hepatitis E virus (HEV) is the prototype of the family Hepeviridae and the causative agent of common acute viral hepatitis. Genetically diverse HEV-related viruses have been detected in a variety of mammals and some of them may have zoonotic potential. In this study, we tested 278 specimens collected from seven wild s...

journal_title：Virologica Sinica

authors： Wang B,Li W,Zhou JH,Li B,Zhang W,Yang WH,Pan H,Wang LX,Bock CT,Shi ZL,Zhang YZ,Yang XL

更新日期：2018-02-01 00:00:00

abstract：:Neutralizing antibodies are considered to be an important protective parameter used in HIV-1 vaccine evaluation. However, the exact role that neutralizing antibodies plays in controlling the disease progression of HIV-1 infected peoples is still undetermined. In this paper, we compared the protective function of the n...

journal_title：Virologica Sinica

authors： Wang Z,Li TY,Li JY,Chen LL,Liu YJ,Li HP,Bao ZY,Wang XL,Zhuang DM,Liu SY,Li L

更新日期：2012-06-01 00:00:00

abstract：:Dengue virus (DENV) and Zika virus (ZIKV) have spread throughout many countries in the developing world and infect millions of people every year, causing severe harm to human health and the economy. Unfortunately, there are few effective vaccines and therapies available against these viruses. Therefore, the discovery ...

journal_title：Virologica Sinica

authors： Ji Z,Li F,Xia Z,Guo X,Gao M,Sun F,Cheng Y,Wu Y,Li W,Ali SA,Cao Z

更新日期：2018-12-01 00:00:00

abstract：:The ubiquitin-like modifier bISG15 is an antiviral protein found in fetal bovine lung (FBL) cells. Bovine Herpesvirus 1(BHV-1), which is a viral pathogen of cattle, can infect FBL cells and induce cytopathic effects. Real-time PCR assays showed that BHV-1's infection could repress the basal or inducible transcription ...

journal_title：Virologica Sinica

authors： Liu C,Kong XH,Qiao WT,Geng YQ

更新日期：2011-12-01 00:00:00

abstract：:Receptors interaction protein 2 (RIP2) is a specific adaptor molecule in the downstream of NOD2. The role of RIP2 during foot-and-mouth disease virus (FMDV) infection remains unknown. Here, our results showed that RIP2 inhibited FMDV replication and played an important role in the activation of IFN-β and NF-ĸB signal ...

journal_title：Virologica Sinica

authors： Liu H,Xue Q,Zhu Z,Yang F,Cao W,Liu X,Zheng H

更新日期：2021-01-05 00:00:00