Abstract:
OBJECTIVE:To assess long-term outcome and parameters associated with poor and favorable outcome in patients with a left ventricular ejection fraction (LV-EF) ≤25% and severe mitral regurgitation (MR) after percutaneous edge-to-edge mitral valve repair (pMVR). BACKGROUND:There is no data on long-term outcome in this cohort of patients. METHODS:We analyzed all 34 patients with a LV-EF ≤25% and severe MR treated with pMVR in 2 university hospitals from 2009 to 2012. RESULTS:Mitral regurgitation could be successfully reduced to grade ≤2 in 30 patients (88%). Long-term follow-up (up to 5 years) revealed a steep decline of the survival curve reaching 50% already 8 month after pMVR. In contrast, estimated survival of the remaining patients showed a favorable long-term outcome. Patients deceased during the first year presented with higher right ventricular tricuspid pressure gradient (RVTG) (44.5 ± 8.4 mmHg vs. 35.2 ± 15.4 mmHg, P = 0.035) and worse RV-function (P = 0.014) prior to the procedure. One-year mortality of patients with pulmonary hypertension and depressed RV-function (n = 22) was very high (77%) compared to the remaining patients (n = 12, mortality rate of 0%, P = 0.0001). CONCLUSIONS:Although pMVR lead to a successful reduction of MR in patients with a LV-EF ≤25%, 1-year mortality in this cohort was very high. However, a subgroup of patients showed a favorable long-term outcome after pMVR. Especially the right ventricular parameters sustained RV-function and absence of pulmonary hypertension-easily assessed with echocardiography-might be used to identify this subgroup and encourage pMVR in these patients.
journal_name
J Interv Cardioljournal_title
Journal of interventional cardiologyauthors
Orban M,Braun D,Orban M,Grebmer C,Sibbing D,Thaler R,Tittus J,Wimbauer F,Lesevic H,Sonne C,Mehilli J,Ott I,Näbauer M,Massberg S,Boekstegers P,Hausleiter Jdoi
10.1111/joic.12193subject
Has Abstractpub_date
2015-04-01 00:00:00pages
164-71issue
2eissn
0896-4327issn
1540-8183journal_volume
28pub_type
杂志文章abstract:OBJECTIVES:Our aim was to establish the frequency of arterial anatomic variations and its relation to coronary procedural outcome in patients undergoing a first transradial coronary procedure. METHODS:This was a single center prospective study. A total of 1,446 consecutive patients undergoing their first transradial c...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2012.00693.x
更新日期:2012-08-01 00:00:00
abstract:OBJECTIVES:To compare the absorption of 300 mg clopidogrel administered crushed via nasogastric (NG) tube versus whole tablets taken orally in healthy volunteers. BACKGROUND:Earlier antiplatelet therapy has proven benefits in treatment of myocardial infarction and in patients undergoing PCI. Aspirin can be delivered e...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2009.00475.x
更新日期:2009-08-01 00:00:00
abstract:BACKGROUND:The latest generation of interactive cardiac magnetic resonance (MR) scanners has made cardiac interventions with real-time MRI possible. To date, cardiac MRI has been mostly applied to measure myocardial perfusion, viability, and regional function, but now the application of cardiac MRI can be extended to c...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2004.01712.x
更新日期:2004-02-01 00:00:00
abstract:OBJECTIVES:To determine whether drug-eluting stent (DES) coronary complete revascularization (CR) confers clinical benefit over incomplete revascularization (IR) in patients with multivessel coronary artery disease (MVD). BACKGROUND:Clinical benefit of CR over IR in patients with MVD with angina (both stable and unsta...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章,meta分析,评审
doi:10.1111/joic.12390
更新日期:2017-08-01 00:00:00
abstract::Vessel rupture and perforation are important complications of percutaneous treatment of coronary and peripheral arterial disease. These complications can result in abrupt vessel closure, distal organ injury, bleeding into the surrounding tissue, and death. Prompt management of such complications is therefore criticall...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章,评审
doi:10.1111/j.1540-8183.2007.00302.x
更新日期:2008-02-01 00:00:00
abstract:BACKGROUND:There were insufficient data on the prognosis of stenting for patients with trifurcated unprotected left main lesions (UPLMS). METHODS:From the SPEED (stents for percutaneous treatment of coronary artery disease) registry of all percutaneous coronary interventions (PCI) for all types of UPLMS, data of 44 pa...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2010.00569.x
更新日期:2010-08-01 00:00:00
abstract:BACKGROUND:Prevalence of patent foramen ovale (PFO) with detectable right-to-left shunt is higher in young adults with transient ischemic attack (TIA) and stroke compared to the general population. So far, published series included different occluder systems, various indications and regimens of postprocedural anticoagu...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2010.00593.x
更新日期:2011-02-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to evaluate the efficacy of sirolimus-eluting stents (SES) in the treatment of saphenous vein graft (SVG) disease. BACKGROUND:Percutaneous coronary intervention (PCI) of SVG lesions with bare metal stents (BMS) is associated with frequent in-stent restenosis, progression of dise...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2007.00301.x
更新日期:2007-12-01 00:00:00
abstract:INTRODUCTION:Irrigated tip radiofrequency ablation of cardiac arrhythmias was developed to increase the size of the radiofrequency-induced lesion, since cooling of the electrode tip allows use of higher power settings. The purpose of this study was to determine if the increased lesion size during irrigated tip ablation...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2004.09879.x
更新日期:2004-06-01 00:00:00
abstract::Degenerative aortic valve stenosis is the most common valvular heart disease seen in developed countries. Since the implementation of transcatheter aortic valve replacement, there has been a surge of efforts to improve procedural technique as well as reduce mortality. Until recently, the mainstay method of assessment ...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章,评审
doi:10.1111/joic.12478
更新日期:2018-06-01 00:00:00
abstract::Results from clinical trials of glycoprotein IIb/IIIa(GPIIb/IIIa) inhibitors during the past decade have established their current role in the treatment of non-ST-segment elevation acute coronary syndrome and in percutaneous coronary interventions. However, there are still unanswered questions on optimal use of GPIIb/...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章,评审
doi:10.1111/j.1540-8183.2006.00182.x
更新日期:2006-10-01 00:00:00
abstract:BACKGROUND:Postdilatation (PD) with noncompliant balloon during elective percutaneous coronary intervention (PCI) is performed usually in clinical practice in order to optimize stent expansion. However, current knowledge about its use in patients undergoing primary PCI is controversial. This study aims to evaluate the ...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/joic.12041
更新日期:2013-08-01 00:00:00
abstract::The aim of this study was to review current studies relevant to the link between impaired glucose tolerance (IGT), diabetes, and cardiovascular disease. Cardiovascular disease is a major cause of the reduction in life expectancy in patients with diabetes. Seventy-five percent of diabetic patients die prematurely of ca...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章,评审
doi:10.1111/j.1540-8183.2005.00080.x
更新日期:2005-12-01 00:00:00
abstract:BACKGROUND:Rotational atherectomy is used to penetrate resistant coronary lesions from standard balloon dilatation. These lesions may contain heavy calcification or metallic components from previously implanted stents. When the rotablator device is utilized to ablate an undilatable lesion containing metallic stent comp...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2010.00543.x
更新日期:2010-06-01 00:00:00
abstract:BACKGROUND:The economic impact of bleeding in the setting of nonemergent percutaneous coronary intervention (PCI) is poorly understood and complicated by the variety of bleeding definitions currently employed. This retrospective analysis examines and contrasts the in-hospital cost of bleeding associated with this proce...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2009.00431.x
更新日期:2009-06-01 00:00:00
abstract:OBJECTIVES:The authors investigated safety and efficacy of the MitraClip-System (MCS) using a systematic analysis. BACKGROUND:The safety and efficacy of the MCS continues to be debated, and randomized trials are still lacking. METHOD:A systematic literature search was conducted using common medical and scientific dat...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章,meta分析,评审
doi:10.1111/joic.12168
更新日期:2015-02-01 00:00:00
abstract::Coronary angiography, despite its inherent invasiveness and need for contrast media and radiographic exposure, is still routinely employed every year for the diagnostic and therapeutic management of millions of patients with or at risk for coronary artery disease. Whereas approximate visual estimation is the most comm...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章,评审
doi:10.1111/j.1540-8183.2009.00491.x
更新日期:2009-12-01 00:00:00
abstract::Local delivery of immunosuppressive or antiproliferative agents using a drug-eluting stent is a new technology that is supposed to inhibit in-stent restenosis, thus providing a biological and mechanical solution. This technique is a very promising. To date, several agents have been used, including paclitaxel, QP-2, ra...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章,评审
doi:10.1111/j.1540-8183.2002.tb01091.x
更新日期:2002-12-01 00:00:00
abstract::Percutaneous intervention of tortuous coronary arteries can be challenging. We describe four cases that illustrate complications associated with coronary tortuosity (coronary dissection and stent loss) and strategies that can improve procedural success (such as use of soft delivery catheters, deep guide intubation, me...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2008.00374.x
更新日期:2008-12-01 00:00:00
abstract::Aims To compare clinical outcome in Chronic kidney disease (CKD) patients receiving coronary stents according to stent type BMS versus DES and 1st generation versus 2nd generation DES. Methods and Results PubMed, Cinhal, Cochrane, Embase, and Web of Science were searched for studies including CKD patients. CKD was def...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章,meta分析,评审
doi:10.1111/joic.12473
更新日期:2018-06-01 00:00:00
abstract:BACKGROUND:The transradial approach for coronary procedures is associated with a low complication rate, but specific training is considered mandatory. METHODS:Procedural characteristics (contrast dye: CD; fluoroscopy time: FT, patient radiation dose: RD) and local complication rates were prospectively assessed in 784 ...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2010.00603.x
更新日期:2011-02-01 00:00:00
abstract:BACKGROUND:HIV patients on protease inhibitors have greater risk of acute coronary syndromes (ACS) but little is known about treatment-naïve patients. METHODS AND RESULTS:Authors conducted a prospective single-center study from Soweto, South Africa, comparing the clinical and angiographic features of treatment-naïve H...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2009.00520.x
更新日期:2010-02-01 00:00:00
abstract::We describe a patient with an intracardiac intravenous catheter fragment in the right heart that was found during fluoroscopy. The catheter fragment had broken off from an intravenous catheter inserted 25 years previously when the patient was admitted after a road accident. There were no complications during these yea...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2002.tb01080.x
更新日期:2002-10-01 00:00:00
abstract::Despite the growing use of drug-eluting stents, restenosis remains to occur especially in high risk subgroups like patients with diffuse in-stent restenosis. This observation is supporting the search for new and potentially even more effective drug eluting stent systems. Everolimus has been used in conjunction with a ...
journal_title:Journal of interventional cardiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1540-8183.2004.04080.x
更新日期:2004-12-01 00:00:00
abstract:Aim:To investigate the relationship between stent length and changes in microvascular resistance during PCI in stable coronary artery disease (CAD). Methods and Results:We measured fractional flow reserve (FFR), index of microcirculatory resistance (IMR), and coronary flow reserve (CFR) before and after stenting in 42...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1155/2019/1397895
更新日期:2019-12-01 00:00:00
abstract:Objectives:We aimed to identify mechanical and pharmacological revascularization strategies correlated with the index of microcirculatory resistance (IMR) in ST-elevation myocardial infarction (STEMI) patients. Background:Microvascular dysfunction (MVD) after STEMI is correlated with infarct size and poor long-term pr...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1155/2020/5036396
更新日期:2020-07-09 00:00:00
abstract::An intravascular ultrasonic imaging device (40 MHz) was used to obtain in vitro ultrasonic images and matching histologic cross-sections, derived from human vascular specimens. The feasibility of assessing vessel wall morphology as well as the ability to accurately document plaque thickness was determined. Based on ...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.1991.tb01008.x
更新日期:1991-01-01 00:00:00
abstract::Catheter closure of atrial septal defects (ASDs) is an accepted procedure among pediatric cardiologists. We report our early experience with the newest of these devices in clinical trials in the United States. Between April and October 2001, 14 patients were enrolled in an FDA phase II multicenter trial comparing the ...
journal_title:Journal of interventional cardiology
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1046/j.1540-8183.2003.08005.x
更新日期:2003-02-01 00:00:00
abstract:BACKGROUND:These days no codified multidisciplinary protocol has been reported to manage all the different patent foramen ovale (PFO)-mediated syndromes. We sought to propose a multidisciplinary program of diagnosis, treatment, and follow-up of all PFO-mediated syndromes based on an in-hospital multidisciplinary task f...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2006.00141.x
更新日期:2006-06-01 00:00:00
abstract::Catheter-based vascular interventions have been in development worldwide for several decades, leading to remarkable progress in device technology. Mechanical interventional devices, such as angioplasty balloons, atherectomy devices, and stents, were invented and have contributed greatly to the treatment of atheroscler...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章,评审
doi:10.1111/j.1540-8183.2002.tb01070.x
更新日期:2002-10-01 00:00:00