The Impact of Preeclampsia on Women's Health: Cardiovascular Long-term Implications.

Abstract:

Importance:Women with a history of preeclampsia have a 2- to 5-fold increased risk of cardiovascular diseases, which represent almost half of mortality in the female population worldwide. Objective:To summarize the current evidence concerning women's future cardiovascular risk after pregnancies complicated by preeclampsia. Evidence Acquisition:A PubMed and Web of Science search was conducted in English, supplemented by hand searching for additional references. Retrieved articles were reviewed, synthesized, and summarized. Relevant studies on cardiovascular risk after preeclampsia were included. Results:Evidence suggests that the cardiovascular implications of preeclampsia do not cease with delivery, with a significant proportion of women demonstrating persistent asymptomatic myocardial impairment, aortic stiffening, and microcirculatory dysfunction. More severe and early-onset preeclampsia, as well as preeclampsia with concurrent neonatal morbidity, increases the risk of cardiovascular disease later in life. Conclusions and Relevance:As former preeclamptics have been shown to be at increased cardiovascular risk, this identifies a subgroup of women who may benefit from early preventive measures.

journal_name

Obstet Gynecol Surv

authors

Orabona R,Sciatti E,Sartori E,Vizzardi E,Prefumo F

doi

10.1097/OGX.0000000000000846

subject

Has Abstract

pub_date

2020-11-01 00:00:00

pages

703-709

issue

11

eissn

0029-7828

issn

1533-9866

journal_volume

75

pub_type

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