Molecular Alterations of Colorectal Cancer with Inflammatory Bowel Disease.

abstract：:The time-dependent appearance of phospholipase A2 (PLA2) activity in the preservation media of ischemic rat intestinal grafts is described. In controls, Ca2+-dependent, secretory PLA2 activity accumulated rapidly during the first 6 hr of ischemia, followed by a linear increase for up to 48 hr. LDH levels, by contrast,...

journal_title：Digestive diseases and sciences

authors： Sonnino RE,Pigatt L,Schrama A,Burchett S,Franson R

更新日期：1997-05-01 00:00:00

abstract：:The present study reports the results of intravenous cyclosporine in 32 patients with refractory and/or severe attacks of ulcerative colitis (UC). Twenty of 32 patients responded to intravenous cyclosporine; cyclosporine was clinically effective and improved colonic lesions. However, one colonic perforation and one po...

journal_title：Digestive diseases and sciences

authors： Carbonnel F,Boruchowicz A,Duclos B,Soulé JC,Lerebours E,Lémann M,Belaïche J,Colombel JF,Cosnes J,Gendre JP

更新日期：1996-12-01 00:00:00

abstract：:Patients with symptomatic cholelithiasis who represent higher than normal surgical risks may be the most suitable candidates for medical dissolution of gallstones. Chenodeoxycholic acid was given to 97 patients in a dosage of 15 mg/kg of body weight per day for a period of two years. Complete gallstone dissolution occ...

journal_title：Digestive diseases and sciences

authors： Tangedahl T,Carey WD,Ferguson DR,Forsythe S,Williams M,Paradis K,Hightower NC

更新日期：1983-06-01 00:00:00

abstract：:This manuscript is a secondary analysis of a large multicenter randomized controlled trial. The primary study is Cross RK et al., A Randomized Controlled Trial of TELEmedicine for patients with Inflammatory Bowel Disease (TELE-IBD). Am J Gastroenterol, 2019 Mar. ...

journal_title：Digestive diseases and sciences

authors： Bilgrami Z,Abutaleb A,Chudy-Onwugaje K,Langenberg P,Regueiro M,Schwartz DA,Tracy JK,Ghazi L,Patil SA,Quezada SM,Russman KM,Quinn CC,Jambaulikar G,Beaulieu DB,Horst S,Cross RK Jr

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Different factors have been associated with prolonged fluoroscopy time (FT) during endoscopic retrograde cholangiopancreatography (ERCP). AIM:We hypothesize that FT depends on both the anatomical location of the pathology managed during ERCP and the complexity of the ERCP. METHODS:Three centers participate...

journal_title：Digestive diseases and sciences

authors： Alkhatib AA,Abdel Jalil AA,Faigel DO,Pannala R,Crowell M,Harrison ME

更新日期：2015-06-01 00:00:00

abstract：:With the increasing incidence of hepatocellular carcinoma (HCC) and its high mortality rates, effective treatment options are of urgent need, preferably in a multidisciplinary setting. In the management of those patients, interventional radiologists play a key role. In this article, we reviewed the current literature ...

journal_title：Digestive diseases and sciences

authors： Vogl TJ,Gruber-Rouh T

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Pyoderma gangrenosum is a serious cutaneous complication seen in approximately 1 % of patients with inflammatory bowel disease (IBD). Oral corticosteroids are the mainstay treatment, although the evidence supporting their use is weak. AIMS:The purpose of this study was to investigate the characteristics of ...

journal_title：Digestive diseases and sciences

authors： Argüelles-Arias F,Castro-Laria L,Lobatón T,Aguas-Peris M,Rojas-Feria M,Barreiro-de Acosta M,Soto-Escribano P,Calvo-Moya M,Ginard-Vicens D,Chaparro-Sánchez M,Hernández-Durán M,Castro-Senosiain B,Fernández-Villaverde A,García-Sán

更新日期：2013-10-01 00:00:00

abstract：:Mutations in the gene encoding the CYP2C-19 enzyme for PPI metabolism have been shown to enhance the chance for a cure in a H. pylori-positive patients using a two-week dual-therapy regimen involving omeprazole and amoxicillin. However, the impact of CYP2C-19 genetic polymorphism on eradication rates of a one-week tri...

journal_title：Digestive diseases and sciences

authors： Miwa H,Misawa H,Yamada T,Nagahara A,Ohtaka K,Sato N

更新日期：2001-11-01 00:00:00

abstract：:The aim of this study was to compare the effect on HCV RNA levels of using induction dosing with 5 MU interferon-alpha2b (IFN) given daily for four weeks followed by 5 MU IFN given three times a week (TIW) for 44 weeks vs standard noninduction TIW dosing of 5 MU IFN for 48 weeks. We randomly assigned 135 patients with...

journal_title：Digestive diseases and sciences

authors： Gonzalez HJ,Ho SB,Gross JB,Peine C,McKee D,Smith T,Midwest Hepatitis Study Group.

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:It is unclear whether the quality of bowel preparation affects colonoscopic detection of non-polypoid colorectal neoplasms (NP-CRNs). AIM:To evaluate the impact of bowel-cleansing quality on detection of NP-CRNs. METHODS:We performed a retrospective analysis of asymptomatic screening colonoscopy cases afte...

journal_title：Digestive diseases and sciences

authors： Oh CH,Lee CK,Kim JW,Shim JJ,Jang JY

更新日期：2015-08-01 00:00:00

abstract：:Autoimmune hepatitis has two major variant phenotypes in which the features of classical disease are co-mingled with those of primary biliary cirrhosis or primary sclerosing cholangitis. These overlap syndromes lack codified diagnostic criteria, established pathogenic mechanisms, and confident management strategies. T...

journal_title：Digestive diseases and sciences

authors： Czaja AJ

更新日期：2013-02-01 00:00:00

abstract：:We studied intraesophageal pressure changes in patients with symptoms of gastroesophageal reflux and an abnormal 24-hr pH monitoring record (N = 52). Our method was simultaneous esophageal manometry and pH monitoring. We observed a three-component esophageal manometric sequence (EMS). When this sequence recurred over ...

journal_title：Digestive diseases and sciences

authors： Shay SS,Eggli D,Oliver G,Peura DA,Johnson LF

更新日期：1989-09-01 00:00:00

abstract：:Patients affected by diabetes mellitus are reported to have an increased incidence of gallbladder abnormalities. The pathophysiologic mechanisms for this phenomenon are unclear. In the present study ultrasonography was used to determine gallbladder emptying in response to a meal or separate cephalic or hormonal stimul...

journal_title：Digestive diseases and sciences

authors： Fiorucci S,Bosso R,Scionti L,DiSanto S,Annibale B,Delle Fave G,Morelli A

更新日期：1990-09-01 00:00:00

abstract：:The changes in plasma and duodenal cholecystokinin (CCK) concentrations after pancreatic duct occlusion were examined in rats. The rats were sacrificed 1, 3, 7, 10, 14, and 30 days after occlusion of the duct. Histological examination showed acute inflammation on days 1 and 3 after duct occlusion, interstitial fibrosi...

journal_title：Digestive diseases and sciences

authors： Miyasaka K,Funakoshi A,Jimi A,Nakamura R,Matsumoto M,Kitani K

更新日期：1992-03-01 00:00:00

abstract：:A gangliocytic paraganglioma (GP) is an extremely rare neurogenic tumor nearly located in the second portion of the duodenum and has been regarded as benign. We report a case of duodenal GP in a 53-year-old man. The GP arose in the second portion of the duodenum and was shown by histological examination to consist of ...

journal_title：Digestive diseases and sciences

authors： Morita T,Tamura S,Yokoyama Y,Onishi T,Kuratani Y,Mizuta H,Onishi S

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND:The endoscopic detection of esophageal cancer is suboptimal in both patients referred with dyspeptic symptoms and those enrolled in Barrett's surveillance programs. MCM5 expression in cells collected from gastric fluid may be correlated with the presence of dysplasia or adenocarcinoma. Analysis of this bioma...

journal_title：Digestive diseases and sciences

authors： Everson M,Magee C,Alzoubaidi D,Brogden S,Graham D,Lovat LB,Novelli M,Haidry R

更新日期：2019-10-01 00:00:00

abstract：:Nonalcoholic steatohepatitis (NASH) is characterized by diffuse fatty infiltration in the liver and ballooning degeneration and inflammation in hepatocytes. We aimed to study the protective effect of soy isoflavones on experimental NASH and their effects on plasma paraoxanese and arylesterase levels in rats. Twenty-ei...

journal_title：Digestive diseases and sciences

authors： Ustundag B,Bahcecioglu IH,Sahin K,Duzgun S,Koca S,Gulcu F,Ozercan IH

更新日期：2007-08-01 00:00:00

abstract：:Isoamylase distribution in the urine of normal individuals and patients admitted to the hospital with hyperamylasemia was determined by a wheat inhibitor mmethod and compared to results obtained by cellulose-acetate electrophoresis. We report two cases where the inhibitor ethod failed to give accurate results in urine...

journal_title：Digestive diseases and sciences

authors： Gersten M,Bank S,Lendvai S

更新日期：1983-11-01 00:00:00

abstract：:After gastrectomy, Roux-Y limb reconstruction leads to duodenojejunal motor disturbances. Because motilin and pancreatic polypeptide (PP) play a role in the regulation of digestive motility, their plasma concentrations were determined in rats after Roux-Y gastrectomy. Three months after a distal Roux-Y gastrectomy, co...

journal_title：Digestive diseases and sciences

authors： Le Blanc-Louvry I,Ducrotte P,Chayvialle JA,Coquerel A,Michot F,Ténière P

更新日期：2000-08-01 00:00:00

abstract：:Rectally administered suspensions of 5-aminosalicylic acid (5-ASA) are topically effective in treating left-sided ulcerative colitis. The extent to which the contents of these enemas are distributed to inflamed mucosal linings has not previously been determined. This study was undertaken to validate a technique for la...

journal_title：Digestive diseases and sciences

authors： Vitti RA,Meyers F,Knight LC,Siegel JA,Malmud LS,Fisher RS

更新日期：1989-11-01 00:00:00

abstract：BACKGROUND:Data on ERCP nurses and associate (ERCP-NA) training and comfort are lacking. Healthcare industry representative (HCIR) influence may be greater in low-volume units (LVUs) due to decreased procedure and device familiarity. AIM:The aim of this study was to compare ERCP-NA training, safety, and HCIR relations...

journal_title：Digestive diseases and sciences

authors： Keswani RN,Malpas P,Lynch SE,Coté GA

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Biliary cannulation failure is a major problem during endoscopic retrograde cholangiopancreatography. It remains unclear how duodenal papilla morphology affects biliary cannulation. Therefore, we proposed a new classification system for the duodenal papilla based on oral protrusion pattern (ratio of the leng...

journal_title：Digestive diseases and sciences

authors： Watanabe M,Okuwaki K,Kida M,Imaizumi H,Yamauchi H,Kaneko T,Iwai T,Hasegawa R,Miyata E,Masutani H,Tadehara M,Adachi K,Koizumi W

更新日期：2019-08-01 00:00:00

abstract：:Gastroparesis often precludes gastric enteral nutrition (EN) in critically ill patients. Our aim was to determine the feasibility of bedside microendoscopic placement of nasointestinal feeding tubes to facilitate enteral nutrition in critically ill patients with poor gastric emptying. Nine mechanically ventilated pati...

journal_title：Digestive diseases and sciences

authors： Taylor SJ,Przemioslo R,Manara AR

更新日期：2003-04-01 00:00:00

abstract：:A randomized controlled clinical study was conducted to determine (a) whether basic aluminum sucrose sulfate (sucralfate) is effective in preventing or reducing gastric ulcer recurrence, and (b) the clinical parameters contributing to ulcer recurrence after endoscopically proved healing has been effected. A total of 1...

journal_title：Digestive diseases and sciences

authors： Miyake T,Ariyoshi J,Suzaki T,Oishi M,Sakai M,Ueda S

更新日期：1980-01-01 00:00:00

abstract：:Alterations in insulin and glucagon levels might account for the plasma amino acid imbalance of cirrhotics. In order to verify this hypothesis we evaluated basal insulin, glucagon, branched-chain amino acids, aromatic amino acids, and free tryptophan in 13 controls and 37 cirrhotics divided on the basis of their menta...

journal_title：Digestive diseases and sciences

authors： Marchesini G,Forlani G,Zoli M,Angiolini A,Scolari MP,Bianchi FB,Pisi E

更新日期：1979-08-01 00:00:00

abstract：:The effect of secretin and somatostatin on secretion of epidermal growth factor (EGF) from Brunner's glands was investigated in rats. Secretin increased volume secretion and the median output of EGF rose from 720 fmol/5 hr (total range 460-1320) in controls to 2065 fmol/5 hr (total range 1560-2730) at a dose of 50 pmo...

journal_title：Digestive diseases and sciences

authors： Olsen PS,Kirkegaard P,Poulsen SS,Nexø E

更新日期：1994-10-01 00:00:00

abstract：:We examined the preventive effect of metoclopramide on the development of esophageal varices in a rat model. Thirty rats were divided into three groups: metoclopramide (7.5 mg/kg twice a day, intraperitoneally), control group I (saline 2 ml/kg twice a day, intraperitoneally), and control group II (incised lower esopha...

journal_title：Digestive diseases and sciences

authors： Ohta M,Hashizume M,Tanoue K,Ueno K,Komori K,Ishii T,Kitano S,Sugimachi K

更新日期：1994-09-01 00:00:00

abstract：:We report a rare case of secondary involvement of the gallbladder by metastatic renal cell carcinoma. A 71-year-old man was diagnosed as having a polypoid mass within the gallbladder when he underwent right nephrectomy for a renal cell carcinoma. A preoperative diagnosis of simultaneous carcinoma of the gallbladder wa...

journal_title：Digestive diseases and sciences

authors： Satoh H,Iyama A,Hidaka K,Nakashiro H,Harada S,Hisatsugu T

更新日期：1991-04-01 00:00:00

abstract：:Achalasia is the best described motor disorder of the esophagus. Associations with familial glucocorticoid deficiency and alacrima (triple A syndrome) have been described in the pediatric population, but no attention has been paid to the possibility of this association in adults. Tear production was assessed in 20 pat...

journal_title：Digestive diseases and sciences

authors： Verma S,Brown S,Dakkak M,Bennett JR

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND:Diagnosis of pediatric inflammatory bowel diseases (IBD) remains challenging. We aimed at the value of immunohistochemical assessment of CD30+ lymphocytes in the intestinal mucosa in differential diagnosis between pediatric Crohn's disease (CD) and ulcerative colitis (UC) and its utility as a predictor of fu...

journal_title：Digestive diseases and sciences

authors： Fabian O,Hradsky O,Drskova T,Mikus F,Zamecnik J,Bronsky J

更新日期：2018-07-01 00:00:00