Abstract:
BACKGROUND:Diagnosis of onychomycosis using the periodic acid-Schiff (PAS) test for sensitive identification of hyphae and fungal culture for identification of species has become the mainstay for many clinical practices. With the advent of polymerase chain reaction (PCR) testing, physicians can identify a fungal toenail infection quickly with the added benefit of species identification. We compared PAS testing with multiplex PCR testing from a clinical perspective. METHODS:A total of 209 patients with clinically diagnosed onychomycosis were recruited. A high-resolution picture was taken of the affected hallux nail, and the nail was graded using the Onychomycosis Severity Index. A proximal sample of the affected toenail and subungual debris were obtained and split into two equal samples. One sample was sent for multiplex PCR testing and the other for PAS testing. The results were analyzed and compared. RESULTS:Six patients were excluded due to insufficient sample size for PCR testing. Of the remaining 203 patients, 109 (53.7%) tested positive with PAS, 77 (37.9%) tested positive with PCR. Forty-one patients tested positive with PAS but negative with PCR, and nine tested positive with PCR but negative with PAS. CONCLUSIONS:Physicians should continue the practice of using PAS biopsy staining for confirmation of a fungal toenail infection before using oral antifungal therapy. Because multiplex PCR allows species identification, some physicians may elect to perform both tests.
journal_name
J Am Podiatr Med Assocjournal_title
Journal of the American Podiatric Medical Associationauthors
Caldwell B,Uchmanowicz K,Kawalec JS,Petrofski S,Kurzel Cdoi
10.7547/18-048subject
Has Abstractpub_date
2020-11-01 00:00:00issue
6eissn
8750-7315issn
1930-8264pii
449536journal_volume
110pub_type
杂志文章abstract:BACKGROUND:Lower limb amputations (LLAs) are a major debilitating complication of diabetes. The toe and flow model (TFM) describes the framework for multidisciplinary centers aiming to reduce this complication. In this study, we investigate the efficacy of the TFM to reduce diabetes-related major LLAs in comparison wit...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/19-137
更新日期:2019-11-01 00:00:00
abstract::A review of 12 cases of bony tumors involving the talus is presented. Giant cell tumor was the most common tumor. Malignant tumors should be treated by surgical ablation followed by chemotherapy. There are good results after excision or curettage and bone grafting in the treatment of benign neoplasms. Giant cell tumor...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/87507315-84-8-379
更新日期:1994-08-01 00:00:00
abstract:BACKGROUND:This study examined the success of an admission screen in identifying applicants who will fail Part I or Part II of the Podiatric Boards on the first attempt. METHODS:A logistic regression model was used to predict failure on the Podiatric Boards. RESULTS:The biology Medical College Admission Test (MCAT) s...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/1020485
更新日期:2012-11-01 00:00:00
abstract::Multiple surgical procedures have been described for the correction of hallux limitus deformity. We describe a new modification of the Youngswick procedure for the surgical treatment of hallux limitus. Other procedures for hallux limitus correction are also discussed. This modified Youngswick procedure will provide a ...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/0970420
更新日期:2007-09-01 00:00:00
abstract::Ganglion cysts have been recorded in many areas throughout the body. Intratendinous ganglion cysts in the foot are very rare. We present the case of 51-year-old woman with a recurrent right foot ganglion cyst. Surgical excision revealed a ganglion cyst in the tendon sheath of the extensor digitorum longus. It is impor...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/19-046
更新日期:2020-01-01 00:00:00
abstract::The authors present a previously undescribed torsion located within the tendon of peroneus brevis. The musculotendinous unit of peroneus brevis was isolated from 46 lower extremities of cadavers. A goniometer was constructed and utilized to quantify the degree of torsion located within each peroneus brevis tendon. Tor...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/87507315-87-10-490
更新日期:1997-10-01 00:00:00
abstract::Painful lesions on the plantar aspect of the interphalangeal joint of the great toe respond well to surgical excision of the accessory bone found lying superior to or within the flexor hallucis longus tendon. Several incisional approaches are available, each with potential advantages and disadvantages. Failure to cons...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/87507315-86-3-105
更新日期:1996-03-01 00:00:00
abstract::Plantar pressure-measurement technology is being increasingly used by podiatric physicians and surgeons in both clinical practice and research. The authors present normal reference-range values for peak pressure, mean pressure, and pressure-time integral obtained from 30 healthy subjects using a two-step recording tec...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/87507315-90-6-295
更新日期:2000-06-01 00:00:00
abstract:BACKGROUND:Use of thicker and longer (four cortices) screws or of multiple screws seems to be more stable and efficient for syndesmosis fixation. METHODS:A three-dimensional finite element model of an ankle was constructed from serial axial sections from an existing two-dimensional computed tomographic image. Construc...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/1030174
更新日期:2013-05-01 00:00:00
abstract::During examination of an 11-year-old boy who had injured his right ankle, a benign tibial bone tumor was incidentally discovered. The bone tumor was initially treated with conservative care. When the patient returned with pain and an enlarging lesion, surgery was performed to prevent pathologic fracture. This case dem...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/0960351
更新日期:2006-07-01 00:00:00
abstract:BACKGROUND:The aim of this study was to observe the pressure changes in the felt padding used to off-load pressure from the first metatarsal head, the effects obtained by different designs, and the loss of effectiveness over time. METHOD:With a study population of 17 persons, two types of 5-mm semicompressed felt padd...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/17-146
更新日期:2019-11-01 00:00:00
abstract:BACKGROUND:The foot is the foundation of the body. The stability of the osseous hindfoot structure is crucial in bipedal locomotion. The subtalar joint is responsible for conversion of the rotatory forces of the lower extremities and dictates the movements of the midtarsal joints and the forefoot. In a hyperpronated fo...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/1010390
更新日期:2011-09-01 00:00:00
abstract:BACKGROUND:Capsulorrhaphy restricts the motion of the first metatarsophalangeal joint (MTPJ) in hallux valgus surgery. However, changes in motion of the first MTPJ immediately after surgery that resulted from different capsulorrhaphy methods have not been compared. The primary aim of this study was to compare the immed...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/17-115
更新日期:2019-07-01 00:00:00
abstract::Onychomycosis is the most frequently encountered condition in podiatric practice in the United States. A variety of modalities are available to confirm the presumptive diagnosis of onychomycosis. This study was conducted to compare the results of in-office dermatophyte test medium cultures with those of mycology labor...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/87507315-90-9-450
更新日期:2000-10-01 00:00:00
abstract:BACKGROUND:This study was performed to determine whether a relationship exists regarding academic achievement between years 1 and 2 of podiatric medical education at Des Moines University. Furthermore, this study evaluates the relationship between academic performance in the first 2 years and clinical performance in ye...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/1020314
更新日期:2012-07-01 00:00:00
abstract::Amputation at the level of the ankle joint is a valuable but underused procedure for a variety of conditions affecting the foot and ankle. The procedure provides a comfortable and durable stump that allows the lower-extremity amputee to function with minimal disability. This article reviews the indications for Syme's ...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/87507315-92-4-232
更新日期:2002-04-01 00:00:00
abstract::The authors illustrated a chronic bilateral plantar foot ulcer of several years' duration that was resistant to all forms of conventional therapy, yet was resolved after 13 1/2 weeks of maggot therapy. The contralateral foot ulcer showed no improvement during the same period, despite continual inpatient conventional d...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/87507315-85-4-218
更新日期:1995-04-01 00:00:00
abstract::This case report discusses the presentation, diagnosis, and treatment of a 22-year-old man with extrapulmonary tuberculosis of the foot. Extrapulmonary tuberculosis is extremely rare and accounts for less than 10% of osteoarticular tuberculosis. Radiographic and magnetic resonance imaging correlations are introduced. ...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/0980246
更新日期:2008-05-01 00:00:00
abstract:BACKGROUND:An observational study was conducted to assess the prevalence of onychomycosis in clinically suspected diabetic neuropathic patients and to assess the reliability of the diagnosis. METHODS:One hundred successive type 1 and 2 diabetic patients with diabetic neuropathy were followed. Diabetic neuropathy was d...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/0980135
更新日期:2009-03-01 00:00:00
abstract::Flatfoot may be classified as pathologic or physiologic. Pathologic flatfoot is often characterized by stiffness of the foot, causes disability, and requires treatment. Physiologic flatfoot is a normal variation; it causes no disability and tends to improve with time. Physiologic flatfoot is most common in individuals...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 历史文章,杂志文章,评审
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更新日期:1999-02-01 00:00:00
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journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/1020369
更新日期:2012-09-01 00:00:00
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journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/0950018
更新日期:2005-01-01 00:00:00
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journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/0940395
更新日期:2004-07-01 00:00:00
abstract::Clinicians may have poor sensitivity in determining whether a given diabetic patient with a foot ulcer has osteomyelitis. Thus many turn to diagnostic tests. The literature was reviewed and data on the sensitivity and specificity of five commonly used diagnostic tests were compiled. Using Bayes' theorem, the authors' ...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/87507315-88-7-337
更新日期:1998-07-01 00:00:00
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journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/8750-7315-105.1.8
更新日期:2015-01-01 00:00:00
abstract::The number of partial-foot amputations performed is increasing, and many recommendations have been made regarding the use of prostheses and footwear designed to prevent higher-level amputations in this population. The present study investigated the use of prostheses and shoe inserts and the types of footwear worn by p...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/87507315-91-1-34
更新日期:2001-01-01 00:00:00
abstract:BACKGROUND:We assessed the efficacy of customized foot orthotic therapy by comparing reulceration rates, minor amputation rates, and work and daily living activities before and after therapy. Peak plantar pressures and peak plantar impulses were compared with the patients not wearing and wearing their prescribed footwe...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/1030281
更新日期:2013-07-01 00:00:00
abstract::One hundred thirty-two female basketball players were observed for lower-extremity overuse injury between 1993 and 2004. Athletes studied between 1993 and 1996 did not receive foot orthotic devices and composed the control group. The treatment group comprised athletes studied between 1996 and 2004. Athletes in the tre...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/0960408
更新日期:2006-09-01 00:00:00
abstract::Lupus erythematosus is an enigmatic disease. Its podiatric manifestations are largely cutaneous, but vasculitic involvements may produce complications. The authors review much of the histopathology of lupus erythematosus that is relevant to the podiatric physician and surgeon. Awareness of the serious systemic implica...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章,评审
doi:10.7547/87507315-79-6-281
更新日期:1989-06-01 00:00:00
abstract::The treatment of diabetic foot ulcerations has been a difficult task for podiatrists. Numerous methods and materials have been used in an attempt to alleviate this frustrating and complex treatment dilemma. However, there is one treatment method that has been used successfully for decades on plantar ulcerations of the...
journal_title:Journal of the American Podiatric Medical Association
pub_type: 杂志文章
doi:10.7547/87507315-85-3-172
更新日期:1995-03-01 00:00:00