Abstract:
:In patients with acquired or congenital heart diseases, the systolic pulmonary artery pressure (PAPs) can be predicted using continuous-wave Doppler ultrasound (CWD) measurement of the peak velocity of a tricuspid regurgitation (TR) jet. The aim of this study was to determine whether CWD could be used to accurately estimate PAP in patients with chronic obstructive pulmonary disease (COPD). In 41 patients with stable COPD, we prospectively performed CWD and right heart catheterization. The mean value of PAPs for the entire group was 38.5 +/- 14.9 mm Hg. Pulmonary arterial hypertension (PAPs greater than or equal to 35 mm Hg) occurred in 51 percent (21/41) of patients. Doppler estimation of PAP was impossible in 34 percent (14/41) because of poor signal quality (n = 3), absence of Doppler-detected TR (n = 8), and inadequate TR Doppler signal (n = 3). The PAP could be estimated in 66 percent (27/41) of patients. A statistically significant correlation was found between the Doppler-estimated PAP and the catheter-measured PAPs (r = 0.65; p less than 0.001; SEE = 9 mm Hg). Therefore, CWD appears to be useful for the noninvasive estimation of PAP in patients with COPD. However, this method is associated with two limitations: (1) the high percentage of patients in whom the PAP cannot be estimated by CWD, mainly because of the absence of Doppler-detected TR, and (2) the high value of the standard error of the estimate. The combination of CWD with other Doppler methods should increase the feasibility and accuracy of Doppler echography for the prediction of PAP in patients with COPD.
journal_name
Chestjournal_title
Chestauthors
Laaban JP,Diebold B,Zelinski R,Lafay M,Raffoul H,Rochemaure Jdoi
10.1378/chest.96.6.1258subject
Has Abstractpub_date
1989-12-01 00:00:00pages
1258-62issue
6eissn
0012-3692issn
1931-3543pii
S0012-3692(16)39319-9journal_volume
96pub_type
杂志文章相关文献
CHEST文献大全abstract::To elucidate the criterion for amplitude of circadian FEV1 variation suitable for phase analysis, six FEV1 measurements within a day were made on 346 days in 125 stable asthmatic children aged 8 to 12 years. Since coefficient of variation (CV) of FEV1 within a day in nonasthmatic children in our laboratory is less tha...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.102.3.771
更新日期:1992-09-01 00:00:00
abstract::The effects of six weeks of threshold pressure inspiratory muscle training (IMT) on inspiratory muscle performance, breathing pattern and exercise performance were studied in eight patients with severe airflow obstruction. The results indicated that IMT improved inspiratory muscle performance but did not affect exerci...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.95.3.535
更新日期:1989-03-01 00:00:00
abstract:STUDY OBJECTIVES:We sought to compare catheter studies using a right ventricular ejection fraction (REF) catheter together with echocardiography and MRI in patients with pulmonary hypertension. PATIENTS AND METHODS:We compared hemodynamic findings, echocardiography, and MRI studies in 16 patients with pulmonary hypert...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.120.2.502
更新日期:2001-08-01 00:00:00
abstract::A female patient was treated with high-dose inhaled fluticasone propionate for her asthma. Over 2 years, she developed features of Cushing's syndrome with proximal myopathy, osteopenia, hypertension, depressive psychosis, and cushingoid appearance. She had biochemical evidence of marked adrenal suppression with a 9:00...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.117.2.593
更新日期:2000-02-01 00:00:00
abstract:BACKGROUND:Lung cancer is the most common cause of cancer death in the United States. Cigarette smoking is the main risk factor. Former smokers are at a substantially increased risk for lung cancer compared with lifetime never-smokers. Chemoprevention is the use of specific agents to reverse, suppress, or prevent the p...
journal_title:Chest
pub_type: 杂志文章,实务指引
doi:10.1378/chest.07-1348
更新日期:2007-09-01 00:00:00
abstract:BACKGROUND:Previous studies on pulmonary hypertension (PH) in systemic sclerosis and related disorders used differing patient populations, and defined PH according to different criteria. We have attempted to determine the prevalence and cause of PH in these disorders using a mainly noninvasive cardiopulmonary evaluatio...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.111.1.36
更新日期:1997-01-01 00:00:00
abstract::Patient-focused or patient-centered care is not a new concept, but its value has been overlooked in preference to the technology-based, disease-centered model that has prevailed in medicine for the last 50 years. Patient-focused care includes four broad areas of intervention: communication with patients, partnerships,...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.130.1_suppl.73S
更新日期:2006-07-01 00:00:00
abstract:BACKGROUND:Altitude exposure is associated with mild pulmonary hypertension and decreased exercise capacity. We tested the hypothesis that pulmonary vascular resistance (PVR) contributes to decreased exercise capacity in hypoxic healthy subjects. METHODS:An incremental cycle ergometer cardiopulmonary exercise test and...
journal_title:Chest
pub_type: 杂志文章,随机对照试验
doi:10.1378/chest.08-2222
更新日期:2009-05-01 00:00:00
abstract:BACKGROUND:Spontaneous pneumothorax is a complication that is commonly reported in patients with cystic fibrosis (CF). An understanding of the pathophysiology of this complication and its consequences is important for the management of patients with CF. OBJECTIVE:To identify risk factors associated with pneumothorax a...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.128.2.720
更新日期:2005-08-01 00:00:00
abstract:BACKGROUND:Stress-induced or tako-tsubo cardiomyopathy (TTC) is a rare acute cardiac syndrome characterized by transient left ventricular (LV) dysfunction of uncertain cause and outcome. This study sought to assess the long-term outcome of patients with TTC. METHODS:One-hundred sixteen consecutive patients were prospe...
journal_title:Chest
pub_type: 杂志文章,多中心研究
doi:10.1378/chest.10-1041
更新日期:2011-04-01 00:00:00
abstract:BACKGROUND:Approximately 40% of patients in medical ICUs require mechanical ventilation (MV). Approximately 20% to 25% of these patients will encounter difficulties in discontinuing MV. Multiple studies have suggested that MV has an unloading effect on the respiratory muscles that leads to diaphragmatic atrophy and dys...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.11-1638
更新日期:2012-12-01 00:00:00
abstract:BACKGROUND:Characterizing acute exacerbations of COPD (AECOPD) and individualizing therapy is challenging. Key exacerbation therapies include antibiotics and systemic corticosteroids. Blood eosinophils, when either low or high, may offer a simple, inexpensive distinction to predict beneficial responses to these therapi...
journal_title:Chest
pub_type: 杂志文章,多中心研究
doi:10.1016/j.chest.2019.02.406
更新日期:2019-07-01 00:00:00
abstract:BACKGROUND:The clinical manifestations of bronchial remodeling in asthma and the potential impact of this process on lung function remain unclear. We aimed to determine whether the presence of pathologic features of airway remodeling in patients with asthma was associated with steroid responsiveness in the short term. ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.11-0232
更新日期:2012-06-01 00:00:00
abstract:BACKGROUND:Growing evidence suggests that no-reflow reperfusion after direct percutaneous coronary intervention (d-PCI) is associated with an unfavorable clinical outcome. The purpose of this study was to evaluate whether prerevascularization angiographic morphologic features of infarct-related arteries (IRAs) and time...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.122.4.1322
更新日期:2002-10-01 00:00:00
abstract::Although the principal actions of clonidine are linked to its centrally mediated suppression of sympathetic activity, its inhibition of the renin axis also may contribute to its antihypertensive effects. In patients with essential hypertension studied in a clinical research center, clonidine-induced decreases in diast...
journal_title:Chest
pub_type: 杂志文章
doi:
更新日期:1983-02-01 00:00:00
abstract::To determine if respiratory maneuvers may enhance the response to inhaled bronchodilator drugs, we evaluated the bronchodilator responses when isoproterenol was: inhaled as a bolus high (80 percent VC) compared to low (20 percent VC) lung volumes, and inhaled as a single 800 microgram dose compared to four 200 microgr...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.76.5.501
更新日期:1979-11-01 00:00:00
abstract:BACKGROUND:Portable monitoring is a convenient means for diagnosing sleep apnea. However, data on whether one night of monitoring is sufficiently precise for the diagnosis of sleep apnea are limited. RESEARCH QUESTION:The current study sought to determine the variability and misclassification in disease severity over ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1016/j.chest.2020.01.039
更新日期:2020-07-01 00:00:00
abstract:BACKGROUND:Chronic tobacco smoke exposure results in a broad range of lung pathologies including emphysema, airway disease and parenchymal fibrosis as well as a multitude of extra-pulmonary comorbidities. Prior work using CT imaging has identified several clinically relevant subgroups of smoking related lung disease, b...
journal_title:Chest
pub_type: 杂志文章
doi:10.1016/j.chest.2020.08.2115
更新日期:2020-09-16 00:00:00
abstract:OBJECTIVE:To assess the efficacy, permanence, and safety of thoracoscopic talc poudrage (TTP) for pleurodesis in malignant effusions. DESIGN:Retrospective. PARTICIPANTS:Patients with lifetime follow-up who received TTP in two related centers in Marseilles, France. RESULTS:Three hundred sixty patients were included i...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.110.6.1387
更新日期:1996-12-01 00:00:00
abstract:STUDY OBJECTIVES:We set out to determine whether there is a difference in postoperative pain and recovery after the patient undergoes the axillary muscle-sparing incision (ie, muscle-sparing thoracotomy [MT]) vs the modified posterolateral incision (ie, posterolateral thoracotomy [PT]). DESIGN:Analysis of a database o...
journal_title:Chest
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1378/chest.128.4.2664
更新日期:2005-10-01 00:00:00
abstract::Previous studies have described oxygen delivery (DO2) and oxygen consumption (VO2) relationships in patients with ARDS and other acute diseases that suggest occasions when VO2 may be dependent on the supply of oxygen, ie, DO2. We studied 127 postoperative patients who developed ARDS to evaluate the relationship of DO2...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.102.3.906
更新日期:1992-09-01 00:00:00
abstract:STUDY OBJECTIVES:To evaluate the safety and efficacy of sitaxsentan, an endothelin-A receptor antagonist, in a 12-week, open-label trial of patients with pulmonary arterial hypertension (PAH). PATIENTS:Six children and 14 adults with New York Heart Association (NYHA) functional class II, III, or IV primary pulmonary h...
journal_title:Chest
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1378/chest.121.6.1860
更新日期:2002-06-01 00:00:00
abstract::A 48-year-old man with unipolar depression and a psychosexual problem concerning his body image was injecting his scrotum repeatedly with olive oil to increase the size of his genitals. He developed respiratory failure following accidental intravenous injection of olive oil and was found to have lipogranulomatous lesi...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.107.3.875
更新日期:1995-03-01 00:00:00
abstract::A 53-year-old woman without any risk factors for coronary artery disease was found to have a congenital intrathoracic left ventricular diverticulum with a narrow long connection to the left ventricular cavity. Coronary angiography revealed normal coronary arteries. The diverticulum was resected and showed three normal...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.98.3.750
更新日期:1990-09-01 00:00:00
abstract::Ventilator-associated pneumonia (VAP), a major cause of ICU infection, results in high morbidity, mortality, and health-care costs. Multiple risk factors for VAP involve complex host factors and ubiquitous pathogens that require several different types of prevention strategies. Prevention efforts should focus on reduc...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.130.1.251
更新日期:2006-07-01 00:00:00
abstract:OBJECTIVES:To describe the anatomy and neurophysiology of the cough reflex. METHODS:A review of the literature was carried out using PubMed and the ISI Web of Knowledge from 1951 to 2004. Most of the referenced studies were carried out in animals CONCLUSIONS:Studies carried out in animals provide suggestive but incon...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.129.1_suppl.33S
更新日期:2006-01-01 00:00:00
abstract::The objective of this study was to determine the following: (1) if standard clinical evaluation is sufficient to provide an accurate estimate of hemodynamic status of unstable ICU patients; (2) the impact of pulmonary artery catheterization (PAC) on diagnosis and treatment plan; and (3) whether therapy provided after ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.99.6.1451
更新日期:1991-06-01 00:00:00
abstract::Pulmonary function test results of individuals with the acquired immunodeficiency syndrome (AIDS) were analyzed to determine the prevalence of abnormally low forced expiratory flow rates and bronchial hyperreactivity. Of 99 individuals with AIDS, a total of 44 (44 percent) had either low forced expiratory flow rates o...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.94.5.945
更新日期:1988-11-01 00:00:00
abstract:STUDY OBJECTIVE:To evaluate the antituberculous treatment responsiveness of endobronchial tuberculosis in the different stages of evolution. DESIGN:A prospective study before and after trial with 9 months of antituberculosis chemotherapy without steroid. PATIENTS AND INTERVENTION:One hundred thirty-six endobronchial ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.103.3.673
更新日期:1993-03-01 00:00:00
abstract::The clinical and histopathologic features of pulmonary amyloidosis were reviewed in 22 patients with systemic amyloidosis who came to autopsy. Eleven of 12 patients (92 percent) with primary amyloidosis had prominent interalveolar amyloid deposits. Symptoms attributable to these deposits were found in four cases (33 p...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.74.5.543
更新日期:1978-11-01 00:00:00