Abstract:
:Polar bears (Ursus maritimus) consume large quantities of seal blubber and other high trophic marine mammals and consequently have some of the highest tissue concentrations of organohalogen contaminants (OHCs) among Arctic biota. In the present paper we carried out a risk quotient (RQ) evaluation on OHC-exposed polar bears harvested from 1999 to 2008 and from 11 circumpolar subpopulations spanning from Alaska to Svalbard in order to evaluate the risk of OHC-mediated reproductive effects (embryotoxicity, teratogenicity), immunotoxicity and carcinogenicity (genotoxicity). This RQ evaluation was based on the Critical Body Residue (CBR) concept and a Physiologically-Based Pharmacokinetic Modelling (PBPK) approach using OHC concentrations measured in polar bear adipose or liver tissue. The range of OHC concentrations within polar bear populations were as follows for adipose, sum polychlorinated biphenyls ∑PCBs (1797-10,537 ng/g lw), sum methylsulphone-PCB ∑MeSO2-PCBs (110-672 ng/g lw), sum chlordanes ∑CHLs (765-3477 ng/g lw), α-hexachlorocyclohexane α-HCH (8.5-91.3 ng/g lw), β-hexachlorocyclohexane β-HCH (65.5-542 ng/g lw), sum chlorbenzenes ∑ClBzs (145-304 ng/g lw), dichlorodiphenyltrichloroethane ∑DDTs (31.5-206 ng/g lw), dieldrin (69-249 ng/g lw), polybrominated diphenyl ethers ∑PBDEs (4.6-78.4 ng/g lw). For liver, the perfluorooctanesulfonic acid (PFOS) concentrations ranged from 231-2792 ng/g ww. The total additive RQ from all OHCs ranged from 4.3 in Alaska to 28.6 in East Greenland bears for effects on reproduction, immune health and carcinogenicity, highlighting the important result that the toxic effect threshold (i.e. RQ>1) was exceeded for all polar bear populations assessed. PCBs were the main contributors for all three effect categories, contributing from 70.6% to 94.3% of the total risk and a RQ between 3.8-22.5. ∑MeSO2-PCBs were the second highest effect contributor for reproductive and immunological effects (0.17 journal_name journal_title authors doi subject pub_date pages eissn issn pii journal_volume pub_type
abstract::Mercury content of twelve podzols from NW Spain was studied to elucidate the main soil properties involved in the Hg accumulation of these soils. The highest average Hg concentrations (HgT) were found in the Bh and Bs horizons (64 and 105 μg kg-1), whereas the lowest occurred in the E horizons (15 μg kg-1). Moderate v...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.110552
更新日期:2021-02-01 00:00:00
abstract::One year-long criteria air pollutants data collected in Beijing were analyzed in this paper, which can support the research on formation, transport and human health effects of air pollutants. This is the first time to study the spatial and temporal variations of criteria pollutants in Beijing using hourly observationa...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2017.01.029
更新日期:2017-04-01 00:00:00
abstract::Food safety assessment and communication have a strong importance in reducing human health risks related to food consumption. The research carried out within the ECsafeSEAFOOD project aims to assess seafood safety issues, mainly related to non-regulated priority environmental contaminants, and to evaluate their impact...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2015.06.038
更新日期:2015-11-01 00:00:00
abstract::A measuring campaign for the assessment of electromagnetic exposure levels from mobile phones in the city center of Leuven, Belgium, has been carried out. The main objective of the assessment is to study the dependency of the exposure of the user by his own mobile phone in terms of location in the city (very close to ...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2019.05.029
更新日期:2019-08-01 00:00:00
abstract::The relationships between inorganic arsenic (iAs) metabolism, selenium (Se) status, and genetic polymorphisms of various genes, commonly studied in populations exposed to high levels of iAs from drinking water, were studied in a Croatian-Slovenian population from the wider PHIME-CROME project. Population consisted of ...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2018.11.045
更新日期:2019-03-01 00:00:00
abstract::The practice of burning sugarcane obtained by non-mechanized harvesting exposes workers and the people of neighboring towns to high concentrations of particulate matter (PM) that is harmful to health, and may trigger a series of cardiorespiratory diseases. The aim of this study was to analyze the chemical composition ...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2014.07.030
更新日期:2014-11-01 00:00:00
abstract:BACKGROUND:Studies of workers exposed to benzene at average air concentrations below one part per million suggest that benzene, a known hematotoxin, causes hematopoietic damage even at low exposure levels. However, evidence of such effects outside of occupational settings and for other volatile organic compounds (VOCs)...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2017.03.048
更新日期:2017-07-01 00:00:00
abstract::An evaluation of the seasonal dynamics of metal (Cd, Cr, Cu, Pb and Zn) phase distribution and speciation, along with different hydrogeochemical facies, was conducted along the entire stretch of a perennial tropical (Brahmaputra) River. Water samples were collected from twelve locations during the monsoon, post-monsoo...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.109265
更新日期:2020-04-01 00:00:00
abstract:BACKGROUND:Ambient air pollution has been associated with acute cardiovascular events; however, the underlying mechanisms remain incompletely understood. We aimed to examine the impacts of ambient air pollutants on cardiac ventricular repolarization in a highly polluted urban region. METHODS:Seventy-three healthy non-...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2019.01.023
更新日期:2019-04-01 00:00:00
abstract::The effects of calcium and magnesium ions on the toxicity of cadmium to the eggs of the freshwater teleost, Oryzias latipes, were determined. Blastulae were immersed in free medium (Ca- and Mg-free), low-Ca medium (0.25 mM Ca), high-Ca medium (1.0 mM Ca), low-Mg medium (0.25 mM Mg), and high-Mg medium (1.0 mM Mg) with...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/s0013-9351(86)80087-1
更新日期:1986-06-01 00:00:00
abstract::It is important to follow up on the health status of inhabitants living in the methyl mercury-polluted area surrounding Minamata City, paying particular attention to diseases not only of the central nervous system but also of other organs. We have been carrying out such concentric studies for more than 10 years. We ha...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1006/enrs.1999.4014
更新日期:2000-06-01 00:00:00
abstract::Particulate matter (PM) composition has a key role in a wide range of health outcomes, such as asthma, chronic obstructive pulmonary disease, lung cancer, cardiovascular disease, and death, among others. Montcada i Reixac, a municipality located in the Barcelona metropolitan area (Catalonia, Spain), for its location a...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2018.04.010
更新日期:2018-08-01 00:00:00
abstract::The non-essential metal mercury (Hg) can have deleterious effects on health of organisms, and tends to bioaccumulate with age in long-lived organisms and to biomagnify along food webs. Because elasmobranchs are fished for human consumption and their Hg levels are frequently above the maximum Hg concentration recommend...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2018.11.024
更新日期:2019-02-01 00:00:00
abstract::Alien species contribute to global change in all marine ecosystems. Environmental variability can affect species distribution and population sizes, and is therefore expected to influence alien species. In this study, we have investigated temporal variability of 11 alien species representing different trophic levels an...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2011.03.002
更新日期:2011-10-01 00:00:00
abstract:BACKGROUND:Traffic noise can act as a stressor and disturb sleep, and has been associated with cardiovascular disease. Recent studies suggest a possible association to metabolic outcomes and adiposity through biological mechanisms related to physiological stress and sleep disturbance. OBJECTIVES:We aimed to investigat...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2015.10.007
更新日期:2015-11-01 00:00:00
abstract::Excessive nitrogen (N) input is one of the most important causative factors of lake eutrophication, which has aroused increasing public attention in past decades. Estrogen contamination is also an increasing environmental problem in aquatic systems around the world. Although both substances usually co-exist in aquatic...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2019.108769
更新日期:2019-12-01 00:00:00
abstract::The human biomonitoring (HBM) of metals is a part of the ongoing project SPoTT for the longitudinal health surveillance of the population living near a waste-to-energy (WTE) incinerator (Turin, Italy). The HBM of metals in the SPoTT population aimed to evaluate: i) reference values (RVs) before the WTE incinerator sta...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2016.04.013
更新日期:2016-07-01 00:00:00
abstract::Human cadmium intake derives mainly from food sources, and cadmium can be present in high concentrations in some offal. A meta-analysis using random effects modeling was carried out to integrate the results of 21 controlled randomized trials in which sheep were fed diets with elevated cadmium levels and cadmium concen...
journal_title:Environmental research
pub_type: 杂志文章,meta分析
doi:10.1016/s0013-9351(03)00084-7
更新日期:2004-02-01 00:00:00
abstract::Natural-occurring minerals representative of six silicate classes were examined for their influence on interferon induction by influenza virus in Rhesus monkey kidney (LLC-MK2) cell monolayers. Minerals within the classes nesosilicate, sorosilicate, cyclosilicate, and inosilicate exhibited either little or marked (50%...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/s0013-9351(87)80040-3
更新日期:1987-08-01 00:00:00
abstract::With the increase of animal slurry produced from livestock production, the monitoring and mitigation of greenhouse gas (GHG) and ammonia (NH3) emissions represent a major issue. Life cycle assessment (LCA) has been used to evaluate the long-term environmental effects of applied strategies and technologies on cattle sl...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.110640
更新日期:2021-01-02 00:00:00
abstract:BACKGROUND:There is mixed evidence implicating prenatal exposure to particulate matter <2.5 μm in aerodynamic diameter (PM2.5) in the risk of gestational diabetes mellitus (GDM) and only one study has examined exposure to PM2.5 constituents, which vary with location because of different emission sources. METHODS:We co...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.109988
更新日期:2020-11-01 00:00:00
abstract::At six paint factories in northern Taiwan, 325 workers participated in a detailed evaluation that included medical and occupational questionnaires, blood sampling, neurobehavioral tests, vibratory perception threshold tests, and thermal perception threshold tests. Because of cultural differences, a Chinese test batter...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1006/enrs.1997.3704
更新日期:1997-01-01 00:00:00
abstract::Volcanic ash samples from four Mount St. Helens' volcanic eruptions were subjected to mineralogical, analytical, and hemolytic studies in order to evaluate their potential for cytotoxicity and fibrogenicity. Plagioclase minerals constituted the major component of the ash with free crystalline silica concentrations ran...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/0013-9351(83)90220-7
更新日期:1983-04-01 00:00:00
abstract:BACKGROUND:Pacific oysters along the North American coast from Washington to Alaska contain concentrations of cadmium (Cd) that are high by comparison with Atlantic oysters, frequently exceeding 2mug/g wet weight, but it is unclear whether this Cd is absorbed by consumers. OBJECTIVES:To determine the effect of oyster ...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2008.01.014
更新日期:2008-06-01 00:00:00
abstract::The air pollution disasters in London in 1952, the Meuse valley in 1930, and in Donoroa, Pennsylvania, in 1948 made it clear that extremely high levels of particulate-based smog could produce large increases in the daily mortality rate. Recent studies of fluctuations in daily air pollution and daily mortality have rep...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1006/enrs.1994.1004
更新日期:1994-01-01 00:00:00
abstract::We developed a high throughput analytical method using on-line solid phase extraction coupled with isotope dilution high-performance liquid chromatography-tandem mass spectrometry (on-line SPE-HPLC-MS/MS) to simultaneously determine the concentrations of 17 polyfluoroalkyl chemicals (PFCs) in house dust. The sample pr...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2009.01.005
更新日期:2009-07-01 00:00:00
abstract::Soil sealing is one of the most pervasive forms of soil degradation that follows urbanization and, despite innovative pavements (i.e. pervious) are being installed in urban areas to mitigate it, there is little research on the effects of pervious pavements on soil water and carbon cycle and on the physiology of urban ...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2017.03.032
更新日期:2017-07-01 00:00:00
abstract::Exposure to inorganic fluoride (F) has been implicated in cardiovascular and kidney dysfunction mainly in adult populations. However, limited epidemiological information from susceptible populations, such as children, is available. In this study we evaluated the relationship of F exposure with some vascular and kidney...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2018.10.028
更新日期:2019-02-01 00:00:00
abstract:BACKGROUND:Exposure to far-field radiofrequency electromagnetic fields (RF-EMF) has raised public concerns in recent decades. However, it is not known if individuals' perception towards the health risks of RF-EMF is dependent on their knowledge of the objectively measured personal RF-EMF exposure levels. OBJECTIVES:Th...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2018.12.058
更新日期:2019-03-01 00:00:00
abstract::Mercury (Hg) has been shown to have immunotoxic effects and to influence the severity of infection. However, the impact of infection on the normal Hg homeostasis in different target organs involved in the disease process has not been studied. In this study, Hg was measured through inductively coupled plasma-mass spect...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2007.08.002
更新日期:2008-02-01 00:00:00