Abstract：
BACKGROUND:Brain metastases from endometrial cancer are rare and poorly described. We aimed to estimate the proportion of brain metastases at our institution that arose from endometrial cancer, and to detail clinicopathologic features and survival outcomes. METHODS:We retrospectively identified and reviewed the charts of 30 patients with brain metastases from endometrial cancer seen at Stanford Hospital from 2008 to 2018. RESULTS:Among all patients with brain metastases, the proportion arising from endometrial cancer was 0.84%. The median age at diagnosis was 62 years (range, 39-79 years), and the median overall survival from brain metastasis diagnosis was 6.8 months (range, 1.0-58.2 months). Most patients harbored endometrioid histology (53.3%), and some had concurrent metastases to lung (50.0%), bone (36.7%), and liver (20.0%). The median time from endometrial cancer diagnosis to brain metastasis development was 20.8 months (range, 1.4 months to 11.2 years), and the median number of brain metastases was 2 (range, 1-20). Patients with non-endometrioid histologies had more brain metastases than those with endometrioid histology (6.21 vs. 2.44, P = 0.029). There was no difference in overall survival by histology. CONCLUSIONS:We describe the largest cohort to date of patients with brain metastases originating from endometrial cancer. These patients represent a small fraction of all patients with brain metastases and have poor prognoses. These data enable providers caring for patients with brain metastases from endometrial cancer to appropriately counsel their patients.
journal_name
World Neurosurgjournal_title
World neurosurgeryauthors
Bhambhvani HP,Zhou O,Cattle C,Taiwo R,Diver E,Hayden Gephart Mdoi
10.1016/j.wneu.2020.11.087subject
Has Abstractpub_date
2020-12-13 00:00:00eissn
1878-8750issn
1878-8769pii
S1878-8750(20)32462-1pub_type
杂志文章abstract：BACKGROUND:Surgical treatment of giant vestibular schwannomas (GVS) is challenging. The philosophy of incomplete tumor resection may balance the preservation of facial nerve function and long-term tumor control. OBJECTIVE:We aimed to evaluate the outcome of facial nerve function and tumor control in treating GVS via o...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2016.06.119
更新日期：2016-10-01 00:00:00
abstract：INTRODUCTION:The aim of this study was to explore the predisposing factors for fracture nonunion after a lateral screw was combined with C2 pedicle/laminar screw for a type II odontoid fracture and hopefully provide references in decision making and surgical planning for spinal surgeons. METHODS:This is a retrospectiv...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2017.09.198
更新日期：2018-01-01 00:00:00
abstract：OBJECTIVE:The interlaminar fusion combination involving C1-C2 screwing fixation is one of the most effective techniques for atlantoaxial dislocation or subluxation, and the bone graft is usually stabilized by wiring constructs. However, some adverse events were reported during the insertion of sublaminar wiring, such a...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2020.03.023
更新日期：2020-06-01 00:00:00
abstract：:Extent of resection and tumor grade are considered the most important predictors of progression-free survival (PFS) in meningiomas. However, adjuvant therapy for atypical meningiomas remains controversial, with variable PFS rates of up to 40%. The current mitotic index (MI) range for atypical meningiomas is broad, com...
journal_title：World neurosurgery
pub_type： 杂志文章,评审
doi：10.1016/j.wneu.2020.06.189
更新日期：2020-10-01 00:00:00
abstract：OBJECTIVE:It was believed that Chiari type II malformation (CM-II) was always present in a myelomeningocele (MMC). In fact, it is associated in about 80% of cases. Improvement of the hindbrain herniation after prenatal closure of MMC has challenged the idea that this condition was irreversible. Only 2 studies report as...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2017.08.152
更新日期：2017-12-01 00:00:00
abstract：BACKGROUND:Abnormalities of the posterior arches of the upper and middle cervical spine that can cause myelopathy are rare, and no reports of such defects at the thoracic spinal level have been published. CASE DESCRIPTION:A 29-year-old male patient reported right arm weakness and pain for 1 year. Magnetic resonance im...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2016.06.088
更新日期：2016-09-01 00:00:00
abstract：BACKGROUND:As ancient Greeks started looking for deities that could fulfill the pragmatic needs of common people, local heroes started being mythologized and worshipped through cults. METHODS:The most widespread such example was Asclepius, possibly a skilled war surgeon who followed military expeditions to Colchis and...
journal_title：World neurosurgery
pub_type： 历史文章,杂志文章,评审
doi：10.1016/j.wneu.2017.04.022
更新日期：2017-07-01 00:00:00
abstract：OBJECTIVE:The chemoreceptor network, consisting of the glossopharyngeal nerve and carotid body (GPN-CB), is essential for the regulation of blood pH. Its ischemic insults after subarachnoid hemorrhage (SAH), which may contribute to acidosis, have not been investigated. METHODS:Twenty-three hybrid rabbits were used. Th...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2017.04.105
更新日期：2017-08-01 00:00:00
abstract：OBJECTIVE:Interbody cage implantation during minimally invasive surgery for transforaminal lumbar interbody fusion (MIS TLIF) presents challenges. Expandable cages when collapsed facilitate insertion; subsequent expansion in situ optimizes endplate contact. This report describes clinical and radiographic outcomes of MI...
journal_title：World neurosurgery
pub_type： 临床试验,杂志文章,多中心研究
doi：10.1016/j.wneu.2016.02.075
更新日期：2016-06-01 00:00:00
abstract：BACKGROUND:After showing the success of mechanical thrombectomy (MT) in treating large-vessel occlusion stroke, the target population has been expanded to include patients with smaller and more distal vessels including the M2 segment of the middle cerebral artery. We compared the procedural and clinical outcomes of pat...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.04.175
更新日期：2019-08-01 00:00:00
abstract：INTRODUCTION:Cervical spinal cord herniation is a rare clinical entity. Reported after previous intradural surgery or surgery complicated by durotomy, patients return several months to years later with symptoms of worsening myelopathy. Herein is presented a case of a 51-year-old female patient with spinal cord herniati...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2017.02.020
更新日期：2017-04-01 00:00:00
abstract：OBJECTIVE:In this study, we sought to characterize contemporary trends in cost and utilization of spinal cord stimulation (SCS). METHODS:The Healthcare Cost and Utilization Project-National Inpatient Sample was queried for inpatient admissions from 2008 to 2014 where SCS was performed. We then determined the rates and...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2020.12.012
更新日期：2020-12-25 00:00:00
abstract：BACKGROUND:Acute myelopathy in cases of thoracic disc herniation (TDH) is an exceptional condition for which the treatment is not codified. Here we present the results of a standardized procedure in 10 patients who underwent surgery for acute myelopathy on TDH between December 2009 and December 2016. METHODS:Our appro...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2017.08.100
更新日期：2017-11-01 00:00:00
abstract：BACKGROUND:Invasive pituitary adenomas often recurred after postoperative radiotherapy and are difficult to treat. Temozolomide (TMZ) is an alkylating cytostaticum and has been reported to reduce pituitary tumor size and hormone hypersecretion, However, this is far from enough. Pituitary adenomas have relatively high e...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.12.174
更新日期：2019-01-10 00:00:00
abstract：OBJECTIVE:Accurate measurement of surgical outcomes is highly desirable to optimize surgical decision-making. An important element of surgical decision making is identification of the patient cohort that will benefit from surgery before the intervention. Machine learning (ML) enables computers to learn from previous da...
journal_title：World neurosurgery
pub_type： 杂志文章,评审
doi：10.1016/j.wneu.2017.09.149
更新日期：2018-01-01 00:00:00
abstract：OBJECTIVE:To assess the safety and efficacy of patient-specific three-dimensional (3D) rapid-prototype printing technology for pedicle screw insertion in patients with adolescent idiopathic scoliosis (AIS). METHODS:The 3D pedicle screw guides were produced after selecting the fixation points for all individual levels ...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2020.08.212
更新日期：2020-12-01 00:00:00
abstract：INTRODUCTION:Treatment of hydrocephalus related to myelomeningocele (MM) is debated. Endoscopic third ventriculostomy (ETV) has been proposed with contrasting results. We report our experience in the management of hydrocephalus related to MM and the advantages of ETV. MATERIAL AND METHODS:From 1994 to 2012, we treated...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2015.07.071
更新日期：2016-03-01 00:00:00
abstract：OBJECTIVE:To compare bony spur resection (BR) with bony spur nonresection (BN) treatment in patients with congenital scoliosis and type I split cord malformation. METHODS:Patients with congenital scoliosis and type I split cord malformation who underwent corrective surgery in a single institution from 2008 to 2015 wer...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.01.265
更新日期：2019-05-01 00:00:00
abstract：OBJECTIVE:This study sought to show and analyze the main authors' experience (P.R. and J.M.C.) in previously coiled aneurysm surgery as an emerging challenge in today's neurosurgical practice. METHODS:Twelve female and 8 male patients, whose ages ranged from 32 to 56 years (average 43.5), underwent surgery between Apr...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2013.09.016
更新日期：2014-07-01 00:00:00
abstract：BACKGROUND:Cervical radiculopathy and cervicalgia are commonly managed with spinal epidural steroid injections in the outpatient setting. Although cervical epidural injections are routinely performed, there is potential for significant complications if proper technique and safety measures are not followed. Spinal cord ...
journal_title：World neurosurgery
pub_type：
doi：10.1016/j.wneu.2020.08.090
更新日期：2020-11-01 00:00:00
abstract：BACKGROUND:The incidence of meningioma has increased drastically recently, particularly in older adults. Surgical intervention has the potential to reduce neurologic symptoms and achieve favorable, long-term outcomes. There is considerable variability in the literature examining the relationship between age and outcome...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2017.09.021
更新日期：2018-01-01 00:00:00
abstract：BACKGROUND:For a long time, a combined transcranial and transfacial approach was the gold standard in the aspect of surgical management of large tumors with sinonasal and skull base involvement. The extended endoscopic endonasal approach for such pathologies has its advantages, but flaws as well, such as anatomical lim...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2020.12.150
更新日期：2021-01-05 00:00:00
abstract：BACKGROUND:Multiple sclerosis (MS) is a common autoimmune and neurodegenerative disease of the central nervous system characterized by inflammatory demyelination, axonal degeneration, and neuronal loss. The exact pathogenesis of MS remains uncertain; however, studies have shown that the development of MS is influenced ...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2016.04.027
更新日期：2016-11-01 00:00:00
abstract：BACKGROUND:Lumbar puncture is a common procedure that can be safely performed in most patients. Certain populations may have increased risk for complications following lumbar puncture, but the significance of basilar invagination is often underappreciated. CASE DESCRIPTION:A 45-year-old woman with basilar invagination...
journal_title：World neurosurgery
pub_type：
doi：10.1016/j.wneu.2020.02.040
更新日期：2020-05-01 00:00:00
abstract：OBJECTIVE:To present a small case series reporting the outcomes of surgical treatment for myelopathy caused by cervical ossification of the ligamentum flavum (OLF). METHODS:The authors assessed 15 cases of myelopathy caused by cervical OLF. Patients were eight women and seven men 37-75 years old (mean age 59.7 years)....
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2010.10.041
更新日期：2011-03-01 00:00:00
abstract：OBJECTIVE:The bi-needle technique is a new technique for percutaneous endoscopic lumbar discectomy. This technique combines the advantages of Yeung endoscopic spine system (YESS) and transforaminal endoscopic spine system (TESSYS) techniques. The aim of this study was to evaluate effectiveness of the bi-needle techniqu...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.06.220
更新日期：2018-11-01 00:00:00
abstract：:The authors discuss the implications of the COVID-19 pandemic on the use of telehealth in the United States. ...
journal_title：World neurosurgery
pub_type： 杂志文章,评审
doi：10.1016/j.wneu.2020.05.092
更新日期：2020-08-01 00:00:00
abstract：BACKGROUND:Primary central nervous system neuroblastoma (PCNSN) is a rare disease, and its incidence, treatment modalities, and survival remain poorly understood. METHODS:The SEER (Surveillance Epidemiology and End Results) database was used to identify patients diagnosed with PCNSN from 1973 to 2013. The incidence an...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2020.04.145
更新日期：2020-08-01 00:00:00
abstract：BACKGROUND:Oblique lateral interbody fusion (OLIF) surgery provides a convenient and minimal access to the lesion disc with few complications; however, the left lumbar sympathetic trunk (LST) lies in the surgical field with a certain incidence of injury. The aim of this study was to describe the anatomic structures of ...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.04.212
更新日期：2018-08-01 00:00:00
abstract：OBJECTIVE:To report on our experience with the Elekta Extend system, a relocatable frame system used in patients with brain metastases for single-session, hypofractionated, or staged hypofractionated Gamma Knife radiosurgery (GKRS); and the evaluation of its efficacy. METHODS:From March 2014 to September 2016, 856 pat...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.07.157
更新日期：2018-11-01 00:00:00
