Stroke rehabilitation outcome: impact of coronary artery disease.


:The frequency of clinically significant coronary artery disease (CAD) among stroke patients and the impact of CAD on stroke rehabilitation were studied in 132 patients with first thrombotic or embolic stroke who participated in comprehensive rehabilitation. Sixty-one patients (46%) had a history of CAD, and 16 of the 61 also had congestive heart failure (CAD-CHF). Patients with CAD, and especially those with CAD-CHF, had significantly longer intervals from stroke onset to rehabilitation admission (p less than 0.001), and once in rehabilitation they experienced three times as many cardiac complications (p less than 0.001). While all patient groups improved function during rehabilitation, those with CAD and CAD-CHF improved significantly less than did those without CAD (p less than 0.01). Patients with CAD did least well with rolling, moving in bed, transferring from a wheelchair to bed, and walking. CHF not only adversely influenced overall function and mobility task performance but also affected the potential for achieving functional gains. These data suggest that specific measures of function and rehabilitation are affected by CAD and that the levels of achievement for patients with CAD-CHF are limited.






Roth EJ,Mueller K,Green D




Has Abstract


1988-01-01 00:00:00














  • Elevated white blood cell count and carotid plaque thickness : the northern manhattan stroke study.

    abstract:BACKGROUND AND PURPOSE:Elevated leukocyte count has been associated with cardiovascular and cerebrovascular disease in several epidemiological studies. We sought to determine whether white blood cell count (WBC) is associated with carotid plaque thickness in a stroke-free, multiethnic cohort. METHODS:For this cross-se...


    pub_type: 杂志文章


    authors: Elkind MS,Cheng J,Boden-Albala B,Paik MC,Sacco RL,Northern Manhattan Stroke Study.

    更新日期:2001-04-01 00:00:00

  • Lipoprotein-associated phospholipase A2 and C-reactive protein for risk-stratification of patients with TIA.

    abstract:BACKGROUND AND PURPOSE:Lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) is a marker of unstable atherosclerotic plaque, and is predictive of both primary and secondary stroke in population-based studies. METHODS:We conducted a prospective study of patients with acute TIA who presented to the ED. Clinical risk sco...


    pub_type: 杂志文章


    authors: Cucchiara BL,Messe SR,Sansing L,MacKenzie L,Taylor RA,Pacelli J,Shah Q,Kasner SE

    更新日期:2009-07-01 00:00:00

  • An epidemiological survey of stroke in Lhasa, Tibet, China.

    abstract:BACKGROUND AND PURPOSE:There have not been any new epidemiological studies related to stroke in Tibet for 20 years. This study aimed to collect stroke data from The City Staff Medical Insurance Registry in Lhasa, Tibet, to describe the incidence, clinical subtypes, and associated risk factors of stroke. METHODS:We use...


    pub_type: 杂志文章


    authors: Zhao Y,Yao Z,D'Souza W,Zhu C,Chun H,Zhuoga C,Zhang Q,Hu X,Zhou D

    更新日期:2010-12-01 00:00:00

  • Role of Computed Tomography Perfusion in Identification of Acute Lacunar Stroke Syndromes.

    abstract:BACKGROUND AND PURPOSE:Lacunar syndromes correlate with a lacunar stroke on imaging in 50% to 60% of cases. Computed tomography perfusion (CTP) is becoming the preferred imaging modality for acute stroke triage. We aimed to estimate the sensitivity, specificity, and predictive values for noncontrast computed tomography...


    pub_type: 杂志文章


    authors: Garcia-Esperon C,Visser M,Churilov L,Miteff F,Bivard A,Lillicrap T,Levi CR,Spratt NJ,Parsons MW

    更新日期:2021-01-01 00:00:00

  • Mechanism of ATP-induced [Ca(2+)](i) mobilization in rat basilar smooth muscle cells.

    abstract:BACKGROUND AND PURPOSE:We have previously reported that extracellular ATP activates P(2u) receptors and increases intracellular free Ca(2+) ([Ca(2+)](i)) by G protein/phospholipase C/inositol 1,4,5-triphosphate pathways in cerebral artery smooth muscle cells. However, the possible contribution of other signaling pathwa...


    pub_type: 杂志文章


    authors: Aoki K,Zubkov AY,Parent AD,Zhang JH

    更新日期:2000-06-01 00:00:00

  • Drip, ship, and retrieve: cooperative recanalization therapy in acute basilar artery occlusion.

    abstract:BACKGROUND AND PURPOSE:In acute basilar artery occlusion, intra-arterial thrombolysis or endovascular mechanical recanalization may result in higher recanalization rates than intravenous thrombolysis. However, many patients are admitted to community hospitals, where endovascular therapy is usually not readily available...


    pub_type: 临床试验,杂志文章


    authors: Pfefferkorn T,Holtmannspötter M,Schmidt C,Bender A,Pfister HW,Straube A,Mayer TE,Brückmann H,Dichgans M,Fesl G

    更新日期:2010-04-01 00:00:00

  • Effects of fluoxetine and maprotiline on functional recovery in poststroke hemiplegic patients undergoing rehabilitation therapy.

    abstract:BACKGROUND AND PURPOSE:In animals, drugs that increase brain amine concentrations influence the rate and degree of recovery from cortical lesions. It is therefore conceivable that antidepressants may influence outcome after ischemic brain injury in humans. We evaluated the effects of the norepinephrine reuptake blocker...


    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Dam M,Tonin P,De Boni A,Pizzolato G,Casson S,Ermani M,Freo U,Piron L,Battistin L

    更新日期:1996-07-01 00:00:00

  • Simultaneous rupture of two intracranial aneurysms: CT diagnosis.

    abstract::A case of simultaneous rupture of two intracranial aneurysms is reported. This is a rare event, and we found no CT reports of such a case. This case points out that the usual assumption of a single aneurysm rupture in a patient with multiple aneurysms may be erroneous and difficult to diagnose angiographically, but ma...


    pub_type: 杂志文章


    authors: Joslyn JN,Williams JP,White JL,White RL

    更新日期:1985-05-01 00:00:00

  • Contribution of atrial fibrillation to incidence and outcome of ischemic stroke: results from a population-based study.

    abstract:BACKGROUND AND PURPOSE:Atrial fibrillation (AF) is a major risk factor for ischemic stroke and its prevalence increases steeply with age. Population-based data on its influence on stroke outcome are scarce. METHODS:We evaluated the prevalence of AF and its influence on prognosis in patients with a first-ever ischemic ...


    pub_type: 杂志文章


    authors: Marini C,De Santis F,Sacco S,Russo T,Olivieri L,Totaro R,Carolei A

    更新日期:2005-06-01 00:00:00

  • A prospective study of cerebral ischemia in the young. Analysis of pathogenic determinants. The National Research Council Study Group.

    abstract:BACKGROUND AND PURPOSE:The etiology of stroke in the young is different from that in older patients and remains unknown in almost one third of the cases. To gain further insight into both pathogenic and etiologic determinants, we prospectively studied a large number of consecutive young adults with focal cerebral ische...


    pub_type: 杂志文章


    authors: Carolei A,Marini C,Ferranti E,Frontoni M,Prencipe M,Fieschi C

    更新日期:1993-03-01 00:00:00

  • Childhood Stature and Growth in Relation to First Ischemic Stroke or Intracerebral Hemorrhage.

    abstract:BACKGROUND AND PURPOSE:Attained height, an indicator of genetic potential and childhood growth environment, is inversely associated with stroke, but the mechanisms are poorly understood. We investigated whether childhood height and growth are associated with ischemic stroke (IS) and intracerebral hemorrhage (ICH). MET...


    pub_type: 杂志文章


    authors: Gjærde LK,Truelsen TC,Baker JL

    更新日期:2018-03-01 00:00:00

  • Are distal protection devices 'protective' during carotid angioplasty and stenting?

    abstract:BACKGROUND AND PURPOSE:To evaluate the periprocedural outcome after carotid artery stenting with embolic brain protection (EBP+) versus without embolic brain protection (EBP-). METHODS:We retrospectively reviewed data from a prospective nonrandomized database of 357 patients who underwent carotid artery stenting in th...


    pub_type: 杂志文章


    authors: Tallarita T,Rabinstein AA,Cloft H,Kallmes D,Oderich GS,Brown RD,Lanzino G

    更新日期:2011-07-01 00:00:00

  • Blood flow and vascular reactivity in collaterally perfused brain tissue. Evidence of an ischemic penumbra in patients with acute stroke.

    abstract::In a group of 48 patients with completed stroke, 8 patients had viable collaterally perfused brain tissue which was accessible for rCBF recordings with a two dimensional technique. All 8 had deep subcortical infarcts on CT-scan, and angiographic occlusion of the arteries normally supplying the infarcted territory. The...


    pub_type: 杂志文章


    authors: Olsen TS,Larsen B,Herning M,Skriver EB,Lassen NA

    更新日期:1983-05-01 00:00:00

  • Homozygous ALDH2*2 Is an Independent Risk Factor for Ischemic Stroke in Taiwanese Men.

    abstract:BACKGROUND AND PURPOSE:The *2 allele of the aldehyde dehydrogenase 2 gene (ALDH2) is the most common variant in Asian populations. The variant resulting in enzyme dysfunction was highly related to coronary artery disease. Recently, genome-wide association studies also discovered that the 12q24 locus near ALDH2 gene was...


    pub_type: 杂志文章


    authors: Sung YF,Lu CC,Lee JT,Hung YJ,Hu CJ,Jeng JS,Chiou HY,Peng GS

    更新日期:2016-09-01 00:00:00

  • Left atrial enlargement and stroke recurrence: the Northern Manhattan Stroke Study.

    abstract:BACKGROUND AND PURPOSE:Although left atrial enlargement (LAE) increases incident stroke risk, the association with recurrent stroke is less clear. Our aim was to determine the association of LAE with recurrent stroke most likely related to embolism (cryptogenic and cardioembolic) and all ischemic stroke recurrences. M...


    pub_type: 临床试验,杂志文章,多中心研究


    authors: Yaghi S,Moon YP,Mora-McLaughlin C,Willey JZ,Cheung K,Di Tullio MR,Homma S,Kamel H,Sacco RL,Elkind MS

    更新日期:2015-06-01 00:00:00

  • Thrombolysis for ischemic stroke in children: data from the nationwide inpatient sample.

    abstract:BACKGROUND AND PURPOSE:Few pediatric reports of thrombolysis exist. We sought to determine national rates of thrombolysis among pediatric ischemic stroke patients using a national database. METHODS:Patients between the ages of 1 and 17 years, entered in the Nationwide Inpatient Sample between 2000 and 2003, with Inter...


    pub_type: 杂志文章


    authors: Janjua N,Nasar A,Lynch JK,Qureshi AI

    更新日期:2007-06-01 00:00:00

  • Hypertensive encephalopathy after bilateral carotid endarterectomy.

    abstract:BACKGROUND:Hypertension occurs frequently after carotid endarterectomy and may lead to cerebral vascular complications and myocardial infarction. Its pathophysiology has recently been related to surgically induced damage of carotid baroreceptors. CASE DESCRIPTION:A 45-year-old normotensive man with no history of epile...


    pub_type: 杂志文章


    authors: Ille O,Woimant F,Pruna A,Corabianu O,Idatte JM,Haguenau M

    更新日期:1995-03-01 00:00:00

  • Shape and volume of lacunar infarcts: a 3D MRI study in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy.

    abstract:BACKGROUND AND PURPOSE:The shape and exact size of lacunar infarcts have been investigated only postmortem. Recent imaging techniques based on triangulation and connectivity can now be used for 3D segmentation of cerebral lesions. The shape and size of lacunar infarcts was investigated using these techniques in 10 cere...


    pub_type: 杂志文章


    authors: Hervé D,Mangin JF,Molko N,Bousser MG,Chabriat H

    更新日期:2005-11-01 00:00:00

  • Intravoxel Incoherent Motion Imaging in Small Vessel Disease: Microstructural Integrity and Microvascular Perfusion Related to Cognition.

    abstract:BACKGROUND AND PURPOSE:Cerebral small vessel disease (SVD) is associated with cognitive impairment. This may be because of decreased microstructural integrity and microvascular perfusion, but data on these relationships are scarce. We determined the relationship between cognition and microvascular perfusion and microst...


    pub_type: 杂志文章


    authors: Zhang CE,Wong SM,Uiterwijk R,Staals J,Backes WH,Hoff EI,Schreuder T,Jeukens CR,Jansen JF,van Oostenbrugge RJ

    更新日期:2017-03-01 00:00:00

  • Carotid arterial remodeling: a maladaptive phenomenon in type 2 diabetes but not in impaired glucose metabolism: the Hoorn study.

    abstract:BACKGROUND AND PURPOSE:Deteriorating glucose tolerance is associated with an increased cardiovascular disease (CVD) risk. The underlying mechanisms remain unclear. Arterial remodeling is the change in structural properties through time in response to atherogenic and/or hemodynamic alterations and aims to maintain circu...


    pub_type: 杂志文章


    authors: Henry RM,Kostense PJ,Dekker JM,Nijpels G,Heine RJ,Kamp O,Bouter LM,Stehouwer CD

    更新日期:2004-03-01 00:00:00

  • Remote Ischemic Conditioning May Improve Outcomes of Patients With Cerebral Small-Vessel Disease.

    abstract:BACKGROUND AND PURPOSE:We aimed to evaluate the efficacy of remote ischemic conditioning (RIC) in patients with cerebral small-vessel disease. METHODS:Thirty patients with cerebral small-vessel disease-related mild cognitive impairment were enrolled in this prospective, randomized controlled study for 1 year. Besides ...


    pub_type: 杂志文章,随机对照试验


    authors: Wang Y,Meng R,Song H,Liu G,Hua Y,Cui D,Zheng L,Feng W,Liebeskind DS,Fisher M,Ji X

    更新日期:2017-11-01 00:00:00

  • Response to intra-arterial and combined intravenous and intra-arterial thrombolytic therapy in patients with distal internal carotid artery occlusion.

    abstract:BACKGROUND AND PURPOSE:The objective of this study was to determine the clinical features, angiographic findings, and response to treatment with thrombolytic therapy in patients with ischemic stroke caused by acute occlusion of the distal internal carotid artery. METHODS:This is a retrospective case series from a pros...


    pub_type: 杂志文章


    authors: Zaidat OO,Suarez JI,Santillan C,Sunshine JL,Tarr RW,Paras VH,Selman WR,Landis DM

    更新日期:2002-07-01 00:00:00

  • Measuring carotid stenosis. Time for a reappraisal.

    abstract:BACKGROUND AND PURPOSE:Data from recent multicenter carotid endarterectomy trials have questioned the validity and reliability of Doppler ultrasound in the assessment of carotid stenosis. METHODS:We prospectively analyzed 45 patients undergoing carotid angiography to compare the North American Symptomatic Carotid Enda...


    pub_type: 杂志文章


    authors: Alexandrov AV,Bladin CF,Maggisano R,Norris JW

    更新日期:1993-09-01 00:00:00

  • Mevastatin, an HMG-CoA reductase inhibitor, reduces stroke damage and upregulates endothelial nitric oxide synthase in mice.

    abstract:BACKGROUND AND PURPOSE:The 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) lower serum cholesterol and decrease the incidence of stroke and cardiovascular disease. There is growing evidence that statins exert some of their beneficial effects independent of cholesterol lowering. Indeed, we...


    pub_type: 杂志文章


    authors: Amin-Hanjani S,Stagliano NE,Yamada M,Huang PL,Liao JK,Moskowitz MA

    更新日期:2001-04-01 00:00:00

  • Soluble CD40L Is a Useful Marker to Predict Future Strokes in Patients With Minor Stroke and Transient Ischemic Attack.

    abstract:BACKGROUND AND PURPOSE:Elevated soluble CD40 ligand (sCD40L) was shown to be related to cardiovascular events, but the role of sCD40L in predicting recurrent stroke remains unclear. METHODS:Baseline sCD40L levels were measured in 3044 consecutive patients with acute minor stroke and transient ischemic attack, who had ...


    pub_type: 杂志文章,随机对照试验


    authors: Li J,Wang Y,Lin J,Wang D,Wang A,Zhao X,Liu L,Wang C,Wang Y,CHANCE Investigators.

    更新日期:2015-07-01 00:00:00

  • Lesion location predicts transient and extended risk of aspiration after supratentorial ischemic stroke.

    abstract:BACKGROUND AND PURPOSE:To assess the association of lesion location and risk of aspiration and to establish predictors of transient versus extended risk of aspiration after supratentorial ischemic stroke. METHODS:Atlas-based localization analysis was performed in consecutive patients with MRI-proven first-time acute s...


    pub_type: 临床试验,杂志文章


    authors: Galovic M,Leisi N,Müller M,Weber J,Abela E,Kägi G,Weder B

    更新日期:2013-10-01 00:00:00

  • Role of the contralateral inferior frontal gyrus in recovery of language function in poststroke aphasia: a combined repetitive transcranial magnetic stimulation and positron emission tomography study.

    abstract:BACKGROUND AND PURPOSE:Functional neuroimaging studies have demonstrated right inferior frontal gyrus (IFG) activation in poststroke aphasia. It remains unclear whether this activation is essential for language performance. We tested this hypothesis in a positron emission tomography (PET) activation study during a sema...


    pub_type: 杂志文章


    authors: Winhuisen L,Thiel A,Schumacher B,Kessler J,Rudolf J,Haupt WF,Heiss WD

    更新日期:2005-08-01 00:00:00

  • Vascular response to carbon dioxide in areas with and without diaschisis in patients with small, deep hemispheric infarction.

    abstract::The reactivity of cerebral blood vessels to changes in PaCO2 in areas of the cerebral cortex with or without diaschisis was investigated in 13 patients in a subacute or chronic stage after a small capsular infarct. A focal area of hypoperfusion (area of diaschisis) was detected in the ipsilateral sensorimotor cortex i...


    pub_type: 杂志文章


    authors: Takano T,Nagatsuka K,Ohnishi Y,Takamitsu Y,Matsuo H,Matsumoto M,Kimura K,Kamada T

    更新日期:1988-07-01 00:00:00

  • Safety, feasibility, and short-term follow-up of drug-eluting stent placement in the intracranial and extracranial circulation.

    abstract:BACKGROUND AND PURPOSE:The use of bare metal stents to treat symptomatic intracranial stenosis may be associated with significant restenosis rates. The advent of drug-eluting stents (DESs) in the coronary circulation has resulted in a reduction of restenosis rates. We report our technical success rate and short-term re...


    pub_type: 杂志文章,多中心研究


    authors: Gupta R,Al-Ali F,Thomas AJ,Horowitz MB,Barrow T,Vora NA,Uchino K,Hammer MD,Wechsler LR,Jovin TG

    更新日期:2006-10-01 00:00:00

  • Prospective follow-up study between 3 and 15 months after stroke: improvements and decline in cognitive function among dementia-free stroke survivors >75 years of age.

    abstract:BACKGROUND AND PURPOSE:Poststroke cognitive impairment is frequent. There are, however, few longitudinal studies examining delayed changes in poststroke cognition. METHODS:As part of a longitudinal study of incident dementia after stroke, 115 older stroke survivors (>75 years of age) without dementia were evaluated at...


    pub_type: 杂志文章


    authors: Ballard C,Rowan E,Stephens S,Kalaria R,Kenny RA

    更新日期:2003-10-01 00:00:00