Stroke rehabilitation outcome: impact of coronary artery disease.


:The frequency of clinically significant coronary artery disease (CAD) among stroke patients and the impact of CAD on stroke rehabilitation were studied in 132 patients with first thrombotic or embolic stroke who participated in comprehensive rehabilitation. Sixty-one patients (46%) had a history of CAD, and 16 of the 61 also had congestive heart failure (CAD-CHF). Patients with CAD, and especially those with CAD-CHF, had significantly longer intervals from stroke onset to rehabilitation admission (p less than 0.001), and once in rehabilitation they experienced three times as many cardiac complications (p less than 0.001). While all patient groups improved function during rehabilitation, those with CAD and CAD-CHF improved significantly less than did those without CAD (p less than 0.01). Patients with CAD did least well with rolling, moving in bed, transferring from a wheelchair to bed, and walking. CHF not only adversely influenced overall function and mobility task performance but also affected the potential for achieving functional gains. These data suggest that specific measures of function and rehabilitation are affected by CAD and that the levels of achievement for patients with CAD-CHF are limited.






Roth EJ,Mueller K,Green D




Has Abstract


1988-01-01 00:00:00














  • Correlations between clinical findings and magnetization transfer imaging metrics of tissue damage in individuals with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy.

    abstract:BACKGROUND AND PURPOSE:We obtained magnetization transfer imaging (MTI) scans from individuals with cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) (1) to investigate the presence, extent, and nature of pathology in white and gray matter outside proton density (PD)-v...


    pub_type: 临床试验,杂志文章


    authors: Iannucci G,Dichgans M,Rovaris M,Brüning R,Gasser T,Giacomotti L,Yousry TA,Filippi M

    更新日期:2001-03-01 00:00:00

  • Addition of brain infarction to the ABCD2 Score (ABCD2I): a collaborative analysis of unpublished data on 4574 patients.

    abstract:BACKGROUND AND PURPOSE:The ABCD system was developed to predict early stroke risk after transient ischemic attack. Incorporation of brain imaging findings has been suggested, but reports have used inconsistent methods and been underpowered. We therefore performed an international, multicenter collaborative study of the...


    pub_type: 杂志文章,多中心研究


    authors: Giles MF,Albers GW,Amarenco P,Arsava MM,Asimos A,Ay H,Calvet D,Coutts S,Cucchiara BL,Demchuk AM,Johnston SC,Kelly PJ,Kim AS,Labreuche J,Lavallee PC,Mas JL,Merwick A,Olivot JM,Purroy F,Rosamond WD,Sciolla R,Rothw

    更新日期:2010-09-01 00:00:00

  • Metabolic impact of shivering during therapeutic temperature modulation: the Bedside Shivering Assessment Scale.

    abstract:BACKGROUND AND PURPOSE:Therapeutic temperature modulation is widely used in neurocritical care but commonly causes shivering, which can hamper the cooling process and result in increases in systemic metabolism. We sought to validate a grading scale to assist in the monitoring and control of shivering. METHODS:A simple...


    pub_type: 杂志文章


    authors: Badjatia N,Strongilis E,Gordon E,Prescutti M,Fernandez L,Fernandez A,Buitrago M,Schmidt JM,Ostapkovich ND,Mayer SA

    更新日期:2008-12-01 00:00:00

  • Caffeine-containing medicines increase the risk of hemorrhagic stroke.

    abstract:BACKGROUND AND PURPOSE:Research on the relationship between caffeine-containing medicines (CCMs) and the risk of hemorrhagic stroke (HS) is sparse. The aim of this study is to evaluate the association between CCMs and the risk of HS. METHODS:We performed a multicenter case-control study in South Korea, from 2002 to 20...


    pub_type: 杂志文章,多中心研究


    authors: Lee SM,Choi NK,Lee BC,Cho KH,Yoon BW,Park BJ

    更新日期:2013-08-01 00:00:00

  • Scanning electron microscopic appraisal of a new micro T-tube.

    abstract::A new micro T-tube, 0.6 mm in outer diameter, has been constructed. Use of this tube has allowed 1-mm common carotid artery (CCA) bypass ofr periods of time up to 22 minutes. After bypass, scanning electron microscopic observation of sutured CCA endothelium showed widespread destruction, scattered attached platelets a...


    pub_type: 杂志文章


    authors: Gregorius FK,Rand RW

    更新日期:1976-09-01 00:00:00

  • Cost-Effectiveness of Solitaire Stent Retriever Thrombectomy for Acute Ischemic Stroke: Results From the SWIFT-PRIME Trial (Solitaire With the Intention for Thrombectomy as Primary Endovascular Treatment for Acute Ischemic Stroke).

    abstract:BACKGROUND AND PURPOSE:Clinical trials have demonstrated improved 90-day outcomes for patients with acute ischemic stroke treated with stent retriever thrombectomy plus tissue-type plasminogen activator (SST+tPA) compared with tPA. Previous studies suggested that this strategy may be cost-effective, but models were der...


    pub_type: 杂志文章,随机对照试验


    authors: Shireman TI,Wang K,Saver JL,Goyal M,Bonafé A,Diener HC,Levy EI,Pereira VM,Albers GW,Cognard C,Hacke W,Jansen O,Jovin TG,Mattle HP,Nogueira RG,Siddiqui AH,Yavagal DR,Devlin TG,Lopes DK,Reddy VK,du Mesnil de Rochemo

    更新日期:2017-02-01 00:00:00

  • Cerebral vasomotor reactivity in normotensive and spontaneously hypertensive rats.

    abstract::Intravenously injected metaraminol induced a larger blood pressure increase in spontaneously hypertensive rats (SHR) than in normotensive controls (NR) when the pressure was raised from the same starting level. Cerebral blood flow (CBF) response in NR was either perfect autoregulation, partial autoregulation or "break...


    pub_type: 杂志文章


    authors: Johansson BB,Nilsson B

    更新日期:1979-09-01 00:00:00

  • Triggers of subarachnoid hemorrhage: role of physical exertion, smoking, and alcohol in the Australasian Cooperative Research on Subarachnoid Hemorrhage Study (ACROSS).

    abstract:BACKGROUND AND PURPOSE:Unaccustomed strenuous physical exertion can trigger myocardial infarction, but little is known about the mechanisms precipitating subarachnoid hemorrhage (SAH). METHODS:We identified all cases of first-ever SAH among the combined populations (2.8 million) of 4 urban centers in Australia and New...


    pub_type: 杂志文章


    authors: Anderson C,Ni Mhurchu C,Scott D,Bennett D,Jamrozik K,Hankey G,Australasian Cooperative Research on Subarachnoid Hemorrhage Study Group.

    更新日期:2003-07-01 00:00:00

  • Safety of intra-arterial thrombolysis in the postoperative period.

    abstract:BACKGROUND AND PURPOSE:Limited systemic fibrinolysis and reduced dosage are features of intra-arterial thrombolyis (IAT) that may be advantageous in the treatment of postoperative strokes. However, IAT may increase the risk of surgical bleeding. We sought to determine the safety of postoperative IAT. METHODS:This was ...


    pub_type: 杂志文章


    authors: Chalela JA,Katzan I,Liebeskind DS,Rasmussen P,Zaidat O,Suarez JI,Chiu D,Klucznick RP,Jauch E,Cucchiara BL,Saver J,Kasner SE

    更新日期:2001-06-01 00:00:00

  • Early NT-ProBNP (N-Terminal Probrain Natriuretic Peptide) Elevation Predicts Malignant Edema and Death After Reperfusion Therapy in Acute Ischemic Stroke Patients.

    abstract:BACKGROUND AND PURPOSE:We aimed to investigate the relationship between early NT-proBNP (N-terminal probrain natriuretic peptide) and all-cause death in patients receiving reperfusion therapy, including intravenous thrombolysis and endovascular thrombectomy (EVT). METHODS:This study included 1039 acute ischemic stroke...


    pub_type: 杂志文章


    authors: Zhang X,Yan S,Zhong W,Yu Y,Lou M

    更新日期:2021-01-01 00:00:00

  • Optimization of Prehospital Triage of Patients With Suspected Ischemic Stroke.

    abstract::Background and Purpose- Prehospital routing algorithms for patients with suspected stroke because of large vessel occlusions should account for likelihood of benefit from endovascular therapy (EVT), risk of alteplase delays, and transport times. We built a mathematical model to give a real-time, location-based optimal...


    pub_type: 杂志文章


    authors: Ali A,Zachrison KS,Eschenfeldt PC,Schwamm LH,Hur C

    更新日期:2018-10-01 00:00:00

  • Impact of admission hyperglycemia on stroke outcome after thrombolysis: risk stratification in relation to time to reperfusion.

    abstract:BACKGROUND AND PURPOSE:We evaluated the impact of admission hyperglycemia (HG) on stroke outcome in relation to the timing of reperfusion in patients treated with tissue plasminogen activator (tPA). METHODS:We studied 138 consecutive stroke patients with a documented middle cerebral artery (MCA) occlusion treated with...


    pub_type: 杂志文章


    authors: Alvarez-Sabín J,Molina CA,Ribó M,Arenillas JF,Montaner J,Huertas R,Santamarina E,Rubiera M

    更新日期:2004-11-01 00:00:00

  • Detection of microembolic signals in patients with middle cerebral artery stenosis by means of a bigate probe. A pilot study.

    abstract:BACKGROUND AND PURPOSE:Middle cerebral artery (MCA) stenosis is a relatively rare occlusive disease with an annual stroke risk of approximately 7% to 8%. However, the frequent coincidence of cardiac or ipsilateral carotid artery disease may lead to difficulties in identifying the relevant embolizing source in symptomat...


    pub_type: 杂志文章


    authors: Nabavi DG,Georgiadis D,Mumme T,Zunker P,Ringelstein EB

    更新日期:1996-08-01 00:00:00

  • Noninvasive assessment of cerebral collateral blood supply through the ophthalmic artery.

    abstract::We assessed the potential of 2-MHz pulsed-wave transorbital Doppler ultrasonography to delineate the role of the ophthalmic artery as a source of collateral cerebral blood supply by comparing oculopneumoplethysmography, transorbital Doppler ultrasonography, periorbital continuous-wave Doppler ultrasonography, and tran...


    pub_type: 杂志文章


    authors: Schneider PA,Rossman ME,Bernstein EF,Ringelstein EB,Otis SM

    更新日期:1991-01-01 00:00:00

  • Race and gender differences in 1-year outcomes for community-dwelling stroke survivors with family caregivers.

    abstract:BACKGROUND AND PURPOSE:Previous research has reported worse outcomes after stroke for women and for African Americans, but few prospective population-based studies have systematically examined demographic differences on long-term stroke outcomes. Race and gender differences in 1-year stroke outcomes were examined using...


    pub_type: 杂志文章


    authors: Roth DL,Haley WE,Clay OJ,Perkins M,Grant JS,Rhodes JD,Wadley VG,Kissela B,Howard G

    更新日期:2011-03-01 00:00:00

  • 4G/4G genotype of PAI-1 gene is associated with reduced risk of stroke in elderly.

    abstract:BACKGROUND AND PURPOSE:Plasminogen activator inhibitor type 1 (PAI-1) is the main inhibitor of fibrinolysis, and high levels may increase the risk of cardiovascular disease. The 4G/5G polymorphism affects PAI-1 gene transcription with lower levels of plasma PAI-1 in the presence of the 5G allele. We investigated whethe...


    pub_type: 杂志文章


    authors: Hoekstra T,Geleijnse JM,Kluft C,Giltay EJ,Kok FJ,Schouten EG

    更新日期:2003-12-01 00:00:00

  • Association of intraoperative transcranial doppler monitoring variables with stroke from carotid endarterectomy.

    abstract:BACKGROUND AND PURPOSE:The outcomes of carotid endarterectomy (CEA) are, in addition to patient baseline characteristics, highly dependent on the safety of the surgical procedure. During the successive stages of the operation, transcranial Doppler (TCD) monitoring of the middle cerebral artery (MCA) was used to assess ...


    pub_type: 杂志文章,多中心研究


    authors: Ackerstaff RG,Moons KG,van de Vlasakker CJ,Moll FL,Vermeulen FE,Algra A,Spencer MP

    更新日期:2000-08-01 00:00:00

  • Beneficial effects of hematopoietic growth factor therapy in chronic ischemic stroke in rats.

    abstract:BACKGROUND AND PURPOSE:Stroke is the leading cause of adult disability worldwide. Currently, there is no effective treatment for stroke survivors. Stem cell factor (SCF) and granulocyte-colony stimulating factor (G-CSF) are the growth factors regulating hematopoiesis. We have previously observed that SCF and G-CSF have...


    pub_type: 杂志文章


    authors: Zhao LR,Berra HH,Duan WM,Singhal S,Mehta J,Apkarian AV,Kessler JA

    更新日期:2007-10-01 00:00:00

  • Cerebral ischemic lesions on diffusion-weighted imaging are associated with neurocognitive decline after cardiac surgery.

    abstract:BACKGROUND AND PURPOSE:Improvements in cardiac surgery mortality and morbidity have focused interest on the neurological injury such as stroke and cognitive decline that may accompany an otherwise successful operation. We aimed to investigate (1) the rate of stroke, new ischemic change on MRI, and cognitive impairment ...


    pub_type: 临床试验,杂志文章


    authors: Barber PA,Hach S,Tippett LJ,Ross L,Merry AF,Milsom P

    更新日期:2008-05-01 00:00:00

  • Measurement of regional brain glucose utilization in vivo using [2(-14)C] glucose.

    abstract::A new technique is described for the autoradiographic determination of regional brain glucose metabolism employing 14C labeled glucose as substrate and measurement principles previously described for whole brain. Regional glucose values correlate closely with those reported for the 14C-deoxyglucose technique. The meth...


    pub_type: 杂志文章


    authors: Hawkins R,Hass WK,Ransohoff J

    更新日期:1979-11-01 00:00:00

  • The morphometry of consecutive segments in cerebral arteries of normotensive and spontaneously hypertensive rats.

    abstract::The media cross-sectional area, the media thickness, the internal radius and the ratio between media thickness and internal radius were determined in consecutive sections of extraparenchymal cerebral arteries of 7- and 12-month-old normotensive and spontaneously hypertensive rats. The study included intracranial pial ...


    pub_type: 杂志文章


    authors: Nordborg C,Fredriksson K,Johansson BB

    更新日期:1985-03-01 00:00:00

  • Decreased glomerular filtration rate is a risk factor for hemorrhagic but not for ischemic stroke: the Rotterdam Study.

    abstract:BACKGROUND AND PURPOSE:Persons with early stages of chronic kidney disease, defined by a decreased glomerular filtration rate (GFR), have an increased risk of cardiovascular disease. It is unclear whether decreased GFR is a risk factor for stroke. We assessed the association between GFR and stroke in a prospective popu...


    pub_type: 杂志文章


    authors: Bos MJ,Koudstaal PJ,Hofman A,Breteler MM

    更新日期:2007-12-01 00:00:00

  • Patient- and Aneurysm-Specific Risk Factors for Intracranial Aneurysm Growth: A Systematic Review and Meta-Analysis.

    abstract:BACKGROUND AND PURPOSE:Follow-up imaging is often performed in intracranial aneurysms that are not treated. We performed a systematic review and meta-analysis on patient- and aneurysm-specific risk factors for aneurysm growth. METHODS:We searched EMBASE and MEDLINE for cohort studies describing risk factors for aneury...


    pub_type: 杂志文章,meta分析,评审


    authors: Backes D,Rinkel GJ,Laban KG,Algra A,Vergouwen MD

    更新日期:2016-04-01 00:00:00

  • Cognitive consequences of thalamic, basal ganglia, and deep white matter lacunes in brain aging and dementia.

    abstract:BACKGROUND AND PURPOSE:Most previous studies addressed the cognitive impact of lacunar infarcts using radiologic correlations that are known to correlate poorly with neuropathological data. Moreover, absence of systematic bilateral assessment of vascular lesions and masking effects of Alzheimer disease pathology and ma...


    pub_type: 杂志文章


    authors: Gold G,Kövari E,Herrmann FR,Canuto A,Hof PR,Michel JP,Bouras C,Giannakopoulos P

    更新日期:2005-06-01 00:00:00

  • Reperfusion in a gerbil model of forebrain ischemia using serial magnetic resonance FAIR perfusion imaging.

    abstract:BACKGROUND AND PURPOSE:Existing methods for the quantitative measurement of the changing cerebral blood flow (CBF) during reperfusion suffer from poor spatial or temporal resolution. The aim of this study was to implement a recently developed MRI technique for quantitative perfusion imaging in a gerbil model of reperfu...


    pub_type: 杂志文章


    authors: Pell GS,Lythgoe MF,Thomas DL,Calamante F,King MD,Gadian DG,Ordidge RJ

    更新日期:1999-06-01 00:00:00

  • Studies on cerebral blood flow and oxygen metabolism in patients with established cerebral infarcts undergoing omental transposition.

    abstract::Regional cerebral blood flow, blood volume, fractional oxygen extraction, and oxygen consumption were measured by positron emission tomography in 4 stroke patients prior to and 6 months following omental transposition surgery. Preoperatively, 3 patients showed the typical picture of established infarction with a match...


    pub_type: 杂志文章


    authors: Herold S,Frackowiak RS,Neil-Dwyer G

    更新日期:1987-01-01 00:00:00

  • Dural arteriovenous shunts: a new classification of craniospinal epidural venous anatomical bases and clinical correlations.

    abstract:BACKGROUND AND PURPOSE:The craniospinal epidural spaces can be categorized into 3 different compartments related to their specific drainage role of the bone and central nervous system, the ventral epidural, dorsal epidural, and lateral epidural groups. We propose this new classification system for dural arteriovenous s...


    pub_type: 杂志文章


    authors: Geibprasert S,Pereira V,Krings T,Jiarakongmun P,Toulgoat F,Pongpech S,Lasjaunias P

    更新日期:2008-10-01 00:00:00

  • Multimodal MRI in cerebral small vessel disease: its relationship with cognition and sensitivity to change over time.

    abstract:BACKGROUND AND PURPOSE:Cerebral small vessel disease is the most common cause of vascular dementia. Interest in using MRI parameters as surrogate markers of disease to assess therapies is increasing. In patients with symptomatic sporadic small vessel disease, we determined which MRI parameters best correlated with cogn...


    pub_type: 杂志文章


    authors: Nitkunan A,Barrick TR,Charlton RA,Clark CA,Markus HS

    更新日期:2008-07-01 00:00:00

  • Vasculogenesis in experimental stroke after human cerebral endothelial cell transplantation.

    abstract:BACKGROUND AND PURPOSE:Despite the reported functional recovery in transplanted stroke models and patients, the mechanism of action underlying stem cell therapy remains not well understood. Here, we examined the role of stem cell-mediated vascular repair in stroke. METHODS:Adult rats were exposed to transient occlusio...


    pub_type: 杂志文章


    authors: Ishikawa H,Tajiri N,Shinozuka K,Vasconcellos J,Kaneko Y,Lee HJ,Mimura O,Dezawa M,Kim SU,Borlongan CV

    更新日期:2013-12-01 00:00:00

  • Lack of evolution of the cerebral blood flow during clinical recovery of a stroke.

    abstract::Cerebral blood flow and clinical parameters were studied in 30 stroke patients at 15th, 30th, 60th, 90th days after the cerebral insult (Xenon 133 inhalation method). The clinical improvement was not accompanied by a progressive normalization of the CBF at rest. No relationship was found between the clinical data and ...


    pub_type: 杂志文章


    authors: Demeurisse G,Verhas M,Capon A,Paternot J

    更新日期:1983-01-01 00:00:00