Bigger is Still Better: A Step Forward in Reperfusion With React 71.


BACKGROUND:While multiple new larger-bore aspiration catheters have been introduced for stroke thrombectomy, sizeable cohort outcome studies are lacking along with meaningful comparative studies to evaluate whether they represent a clinically relevant improvement compared to predecessors. OBJECTIVE:To evaluate comparative angiographic and clinical outcomes between an 071 and 068 aspiration catheter. METHODS:The authors reviewed an institutional thrombectomy database extracting the first 150 consecutive cases utilizing React 71 (Medtronic, Dublin, Ireland) with a comparison of background/demographic, procedural, angiographic, and clinical outcome variables to a cohort of patients treated with our previously most frequently utilized 0.068-inch aspiration catheter. RESULTS:In our React 71 cohort, successful reperfusion (thrombolysis in cerebral infarction [TICI] 2b-3) was achieved in 95% of cases. In comparison to a prior cohort of 96 patients treated with a 0.068-inch catheter, there was no statistically significant difference in rates of successful reperfusion (TICI 2b-3), initial disposition, and 90-d outcome. However, the frequency of single pass cases was significantly higher in the React 71 cohort (47% vs 35%, P = .019 on multivariate analysis) along with the rate of TICI 2c-3 reperfusion after the first pass (26% vs 14%, P = .019 on multivariate analysis), and final TICI 2c-3 reperfusion (39% vs 28%, P = .04 on multivariate analysis). CONCLUSION:While rates of TICI 2b-3 reperfusion and clinical outcome results were similar, our study suggests that a newer, larger bore aspiration catheter may be associated with a greater frequency of single pass cases and higher quality reperfusion, judged as TICI 2c-3 frequency after the first and final pass.






Gross BA,Hudson JS,Tonetti DA,Desai SM,Lang MJ,Jadhav AP,Jankowitz BT,Jovin TG




Has Abstract


2020-12-28 00:00:00








  • The genesis and significance of delayed traumatic intracerebral hematoma.

    abstract::During a 34-month period, 12 cases of delayed traumatic intracerebral hematoma (DTICH) were diagnosed among 162 consecutive prospectively studied patients admitted to the Medical College of Virginia with severe closed head injuries. All patients were unresponsive to command and unable to utter formed words at the time...


    pub_type: 杂志文章


    authors: Gudeman SK,Kishore PR,Miller JD,Girevendulis AK,Lipper MH,Becker DP

    更新日期:1979-09-01 00:00:00

  • Motor evoked potentials elicited from pyramidal stimulation and recorded from the spinal cord in the rat.

    abstract::This study investigated the spinal evoked response to focal electrical stimulation of the sensorimotor cortex in 32 rats. The results demonstrate a long-latency response (beginning at 8 milliseconds) elicited by electrical stimulation, which is distinct from the short-latency motor evoked potential previously reported...


    pub_type: 杂志文章


    authors: Ryder J,Zappulla R,Nieves J

    更新日期:1991-04-01 00:00:00

  • The new generation polestar n20 for conventional neurosurgical operating rooms: a preliminary report.

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    pub_type: 临床试验,杂志文章


    authors: Ntoukas V,Krishnan R,Seifert V

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    pub_type: 杂志文章


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    authors: Ding D,Starke RM,Kano H,Nakaji P,Barnett GH,Mathieu D,Chiang V,Omay SB,Hess J,McBride HL,Honea N,Lee JY,Rahmathulla G,Evanoff WA,Alonso-Basanta M,Lunsford LD,Sheehan JP

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  • Phosphodiesterase 5 inhibition attenuates cerebral vasospasm and improves functional recovery after experimental subarachnoid hemorrhage.

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    authors: Neuwelt EA,Barnett PA,Ramsey FL,Hellström I,Hellström KE,McCormick CI

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    authors: Keane JR

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  • Predictors of Poor Quality of Life 1 Year After Subarachnoid Hemorrhage.

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  • Tuberculum sellae meningioma: a report on management on the basis of a surgical experience with 70 patients.

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    authors: Goel A,Muzumdar D,Desai KI

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    authors: Leary SP,Liu CY,Apuzzo ML

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