Bisphenol A and Its Analogues in Chinese Total Diets: Contaminated Levels and Risk Assessment.

abstract：:Mesenchymal stem cells (MSCs) have shown beneficial effects in the treatment of abdominal aortic aneurysm (AAA). Nonetheless, the biological properties of adipose-derived MSCs (ASCs) from patients with AAA (AAA-ASCs) remain unclear. This study is aimed at investigating the properties of cell phenotype and function of ...

journal_title：Oxidative medicine and cellular longevity

authors： Huang X,Zhang H,Liang X,Hong Y,Mao M,Han Q,He H,Tao W,Jiang G,Zhang Y,Li X

更新日期：2019-11-25 00:00:00

abstract：:Mitochondria are the primary site of cellular energy generation and reactive oxygen species (ROS) accumulation. Elevated ROS levels are detrimental to normal cell function and have been linked to the pathogenesis of neurodegenerative disorders such as Down's syndrome (DS) and Alzheimer's disease (AD). RCAN1 is abundan...

journal_title：Oxidative medicine and cellular longevity

authors： Peiris H,Dubach D,Jessup CF,Unterweger P,Raghupathi R,Muyderman H,Zanin MP,Mackenzie K,Pritchard MA,Keating DJ

更新日期：2014-01-01 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2020/9250512.]. ...

journal_title：Oxidative medicine and cellular longevity

authors： Zhang X,Fu Q,Xu L,Yang Y,Zhao W,Zhang Y,Mi W,Li H

更新日期：2020-08-24 00:00:00

abstract：:Endothelial microparticles are effectors of endothelial damage; however mechanisms involved are unclear. We examined the effects of eMPs on cultured endothelial cells (ECs) and isolated vessels and investigated the role of eMP-derived reactive oxygen species (ROS) and redox signaling in these processes. eMPs were isol...

journal_title：Oxidative medicine and cellular longevity

authors： Burger D,Turner M,Munkonda MN,Touyz RM

更新日期：2016-01-01 00:00:00

abstract：:Eugenia dysenterica ex DC Mart. (Myrtaceae), popularly known as "cagaita," is a Brazilian plant rich in polyphenols and other antioxidant compounds. Aiming to evaluate the potential use of cagaita in pathologies involving oxidative stress, such as neurodegenerative disorders, this study investigated its antioxidant po...

journal_title：Oxidative medicine and cellular longevity

authors： Thomaz DV,Peixoto LF,de Oliveira TS,Fajemiroye JO,da Silva Neri HF,Xavier CH,Costa EA,Dos Santos FCA,de Souza Gil E,Ghedini PC

更新日期：2018-09-19 00:00:00

abstract：:Advanced glycation end products (AGEs), generated through nonenzymatic glycosylation of proteins, lipids, and nucleic acids, accumulate in the body by age thus being considered as biomarkers of senescence. Senescence is characterized by a breakdown of immunological self-tolerance, resulting in increased reactivity to ...

journal_title：Oxidative medicine and cellular longevity

authors： Buttari B,Profumo E,Facchiano F,Ozturk EI,Segoni L,Saso L,Riganò R

更新日期：2013-01-01 00:00:00

abstract：:Inflammation and oxidative stress are pivotal mechanisms for the pathogenesis of ischemia and reperfusion injury (IRI). Vagus nerve stimulation (VNS) may participate in maintaining oxidative homeostasis and response to external stimulus or injury. We investigated whether the in vivo VNS can protect the liver from IRI....

journal_title：Oxidative medicine and cellular longevity

authors： Xia H,Liu Z,Liang W,Zeng X,Yang Y,Chen P,Zhong Z,Ye Q

更新日期：2020-01-21 00:00:00

abstract：:Aluminum ions are especially toxic to plants in acidic soils. Here we present evidences that SO2 protects germinating wheat grains against aluminum stress. SO2 donor (NaHSO3/Na2SO3) pretreatment at 1.2 mM reduced the accumulation of superoxide anion, hydrogen peroxide, and malondialdehyde, enhanced the activities of g...

journal_title：Oxidative medicine and cellular longevity

authors： Zhu DB,Hu KD,Guo XK,Liu Y,Hu LY,Li YH,Wang SH,Zhang H

更新日期：2015-01-01 00:00:00

abstract：:We have focused on determining the range of oxidative stress biomarkers and their dynamic changes in patients at different time points after the acute ischemic stroke (AIS). 82 patients with AIS were involved in our study and were tested: within 24 h from the onset of the attack (group A); at 7-day follow-up (group B)...

journal_title：Oxidative medicine and cellular longevity

authors： Žitňanová I,Šiarnik P,Kollár B,Chomová M,Pazderová P,Andrezálová L,Ježovičová M,Koňariková K,Laubertová L,Krivošíková Z,Slezáková L,Turčáni P

更新日期：2016-01-01 00:00:00

abstract：:Systemic inflammation often induces neuroinflammation and disrupts neural functions, ultimately causing cognitive impairment. Furthermore, neuronal inflammation is the key cause of many neurological conditions. It is particularly important to develop effective neuroprotectants to prevent and control inflammatory brain...

journal_title：Oxidative medicine and cellular longevity

authors： Li Y,Liu T,Li Y,Han D,Hong J,Yang N,He J,Peng R,Mi X,Kuang C,Zhou Y,Han Y,Shi C,Li Z,Guo X

更新日期：2020-09-22 00:00:00

abstract：:We recently showed that activated Ras proteins are localized to the plasma membrane and in the nucleus in wild-type cells growing exponentially on glucose, while in the hxk2Δ strain they accumulated mainly in mitochondria. An aberrant accumulation of activated Ras in these organelles was previously reported and correl...

journal_title：Oxidative medicine and cellular longevity

authors： Amigoni L,Martegani E,Colombo S

更新日期：2013-01-01 00:00:00

abstract：:Background. Oxidative stress plays an important role in the pathogenesis of contrast-induced nephropathy (CIN). The aim of this study was to investigate the antioxidant effects of sulforaphane (SFN) in a rat model of CIN and a cell model of oxidative stress in HK2 cells. Methods. Rats were randomized into four groups ...

journal_title：Oxidative medicine and cellular longevity

authors： Zhao Z,Liao G,Zhou Q,Lv D,Holthfer H,Zou H

更新日期：2016-01-01 00:00:00

abstract：:Detection of free radicals in tissues is challenging. Most approaches rely on incubating excised sections or homogenates with reagents, typically at supraphysiologic oxygen tensions, to finally detect surrogate, nonspecific end products. In the present work, we explored the potential of using intravenously (i.v.) inje...

journal_title：Oxidative medicine and cellular longevity

authors： Proniewski B,Kij A,Sitek B,Kelley EE,Chlopicki S

更新日期：2019-05-22 00:00:00

abstract：:Flavonoids have demonstrated in vivo and in vitro leishmanicidal, trypanocidal, antioxidant, and prooxidant properties. The chemotherapy of trypanosomiasis and leishmaniasis lacks efficacy, presents high toxicity, and is related to the development of drug resistance. Thus, a series of 40 flavonoids were investigated w...

journal_title：Oxidative medicine and cellular longevity

authors： Baldim JL,de Alcântara BGV,Domingos ODS,Soares MG,Caldas IS,Novaes RD,Oliveira TB,Lago JHG,Chagas-Paula DA

更新日期：2017-01-01 00:00:00

abstract：:We have demonstrated that grape seed proanthocyanidins (GSPs) could effectively scavenge hydroxyl radical (•OH) in a dose-dependent manner. Since most of the ionizing radiation- (IR-) induced injuries were caused by •OH, this study was to investigate whether GSPs would mitigate IR-induced injuries in vitro and in vivo...

journal_title：Oxidative medicine and cellular longevity

authors： Huang Y,Zhao H,Cao K,Sun D,Yang Y,Liu C,Cui J,Cheng Y,Li B,Cai J,Gao F

更新日期：2016-01-01 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2017/6487825.]. ...

journal_title：Oxidative medicine and cellular longevity

authors： Oh ST,Park H,Yoon HJ,Yang SY

更新日期：2017-01-01 00:00:00

abstract：:The vascular endothelium plays an essential role in the control of the blood flow. Pharmacological agents like quinone (menadione) at various doses modulate this process in a variety of ways. In this study, Q7, a 2-phenylamino-1,4-naphthoquinone derivative, significantly increased oxidative stress and induced vascular...

journal_title：Oxidative medicine and cellular longevity

authors： Palacios J,Cifuentes F,Valderrama JA,Benites J,Ríos D,González C,Chiong M,Cartes-Saavedra B,Lafourcade C,Wyneken U,González P,Owen GI,Pardo F,Sobrevia L,Buc Calderon P

更新日期：2016-01-01 00:00:00

abstract：:Inhibition of either P2Y12 receptor or the nucleotide-binding oligomerization domain- (NOD-) like receptor pyrin domain containing 3 (NLRP3) inflammasome provides cardioprotective effects. Here, we investigate whether direct NLRP3 inflammasome inhibition exerts additive effects on myocardial protection induced by the ...

journal_title：Oxidative medicine and cellular longevity

authors： Penna C,Aragno M,Cento AS,Femminò S,Russo I,Bello FD,Chiazza F,Collotta D,Alves GF,Bertinaria M,Zicola E,Mercurio V,Medana C,Collino M,Pagliaro P

更新日期：2020-08-03 00:00:00

abstract：:There are a great number of reports with assertions that oxidative stress is produced by organophosphorus compound (OPC) poisoning and is a cofactor of mortality and morbidity in OPC toxicity. In addition, antioxidants have been suggested as adjuncts to standard therapy. However, there is no substantial evidence for t...

journal_title：Oxidative medicine and cellular longevity

authors： Nurulain SM,Ojha S,Tekes K,Shafiullah M,Kalasz H,Adem A

更新日期：2015-01-01 00:00:00

abstract：:Although the role of endothelium in varicose vein development is indisputable, the effect of the pathology on biological properties of endothelial cells remains unclear. Here we examined if the presence of varicose veins affects senescence of endothelial cells (HUVECs) and, if so, what will be the local and systemic o...

journal_title：Oxidative medicine and cellular longevity

authors： Mikuła-Pietrasik J,Uruski P,Aniukiewicz K,Sosińska P,Krasiński Z,Tykarski A,Książek K

更新日期：2016-01-01 00:00:00

abstract：:Azadirachta indica A. Juss. (neem, family: Meliaceae) is perhaps the most commonly used traditional medicinal plant of India. In this study we investigated the protective effect of methanolic neem leaves extract (MNLE; 500 mg/Kg bwt) on rats treated with cisplatin (CDDP)-induced hepatotoxicity. Adult rats were randoml...

journal_title：Oxidative medicine and cellular longevity

authors： Dkhil MA,Al-Quraishy S,Aref AM,Othman MS,El-Deib KM,Abdel Moneim AE

更新日期：2013-01-01 00:00:00

abstract：:The prodrug potential of Mahonia aquifolium, a plant used for centuries in traditional medicine, recently gained visibility in the literature, and the activity of several active compounds isolated from its extracts was studied on biologic systems in vitro and in vivo. Whereas the antioxidative and antitumor activities...

journal_title：Oxidative medicine and cellular longevity

authors： Andreicuț AD,Fischer-Fodor E,Pârvu AE,Ţigu AB,Cenariu M,Pârvu M,Cătoi FA,Irimie A

更新日期：2019-12-14 00:00:00

abstract：:Traumatic brain injury (TBI) represents one of the major causes of mortality and disability in the world. TBI is characterized by primary damage resulting from the mechanical forces applied to the head as a direct result of the trauma and by the subsequent secondary injury due to a complex cascade of biochemical event...

journal_title：Oxidative medicine and cellular longevity

authors： Angeloni C,Prata C,Dalla Sega FV,Piperno R,Hrelia S

更新日期：2015-01-01 00:00:00

abstract：:Taurine (2-aminoethane-sulfonic acid) is a type of amino acids and has numerous physiological and therapeutic functions, including anti-inflammation. However, there are few studies on the anticancer action of taurine. Our previous studies have demonstrated that taurine exhibits an apoptosis-inducing effect on human na...

journal_title：Oxidative medicine and cellular longevity

authors： Wang G,Ma N,He F,Kawanishi S,Kobayashi H,Oikawa S,Murata M

更新日期：2020-05-20 00:00:00

abstract：:This study is aimed at investigating the cytotoxicity, anti-inflammatory, and angiogenic activities of two Boswellia serrata extracts on primary culture of porcine aortic endothelial cells (pAECs). Chemical characterization of a dry extract (extract A) and a hydroenzymatic extract (extract G) of B. serrata was perform...

journal_title：Oxidative medicine and cellular longevity

authors： Bertocchi M,Isani G,Medici F,Andreani G,Tubon Usca I,Roncada P,Forni M,Bernardini C

更新日期：2018-06-25 00:00:00

abstract：:Hypoxia-inducible gene domain family member 1A (Higd1a) has recently been reported to protect cells from hypoxia by helping to maintain normal mitochondrial function. The potential induction of Higd1a under high-fat exposure and whether it could protect cells from oxidative stress attracted our attention. Initially, 0...

journal_title：Oxidative medicine and cellular longevity

authors： Li T,Xian WJ,Gao Y,Jiang S,Yu QH,Zheng QC,Zhang Y

更新日期：2019-04-08 00:00:00

abstract：:Human skeletal muscle is a vital organ involved in movement and force generation. It suffers from deterioration in mass, strength, and regenerative capacity in sarcopenia. Skeletal muscle satellite cells are involved in the regeneration process in response to muscle loss. Tocotrienol, an isomer of vitamin E, was repor...

journal_title：Oxidative medicine and cellular longevity

authors： Lim JJ,Wan Zurinah WN,Mouly V,Norwahidah AK

更新日期：2019-01-10 00:00:00

abstract：:Rosmarinic acid (RA) is a natural compound that is gaining wide popularity owing to its broad-spectrum biological activities. RA is known for its wide range of medicinal properties and therapeutic applications in a vast range of neurodegenerative disorders thus making it a vital natural compound. Human transferrin (hT...

journal_title：Oxidative medicine and cellular longevity

authors： Shamsi A,Anwar S,Shahbaaz M,Mohammad T,Alajmi MF,Hussain A,Hassan I,Ahmad F,Islam A

更新日期：2020-11-05 00:00:00

abstract：:There is accumulating evidence that blood pressure (BP) control significantly reduces the risk of future cardiovascular events in patients with essential hypertension. However, strict BP control is often difficult to maintain, and half of hypertensive patients fail to attain BP goals on single-drug therapy. Therefore,...

journal_title：Oxidative medicine and cellular longevity

authors： Bekki H,Yamamoto K,Sone M,Homma T,Nakata M,Nohara M,Fukami K,Okuda S,Yamagishi S

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:The human Circadian Locomotor Output Cycle protein Kaput (CLOCK) gene was originally discovered as a regulator of essential human daily rhythms. This seemingly innocuous gene was then found to be associated with a multitude of human malignancies, via several biochemical pathways. We aimed to further investig...

journal_title：Oxidative medicine and cellular longevity

authors： Tang X,Guo D,Lin C,Shi Z,Qian R,Fu W,Liu J,Li X,Fan L

更新日期：2015-01-01 00:00:00