Pelvic irradiation for stage II ovarian carcinoma.


:Over a 20-year period, 34 patients with FIGO stage II ovarian carcinoma were treated with postoperative pelvic irradiation at the University of Michigan. Complications of radiation treatment were minimal. The overall actuarial disease-free 5-year survival was 53%. This was not significantly different for substages IIA, IIB, or IIC. Patients with well-differentiated tumors had a significantly better survival than patients with moderate or poorly differentiated tumors (P less than 0.05). The implications for managing stage II ovarian carcinoma are discussed.


Gynecol Oncol


Gynecologic oncology


Terada KY,Morley GW,Roberts JA




Has Abstract


1988-01-01 00:00:00












  • Contemporary management of ovarian germ cell tumors and remaining controversies.

    abstract::Ovarian germ cell tumors (GCTs) are rare in adults, but are more common in adolescents and young adults. Contemporary management of ovarian GCTs is evolving as collaboration among pediatric, medical, and gynecologic oncologists increases, and studies increasingly incorporate female adult patients. Despite an improved ...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章,评审


    authors: Veneris JT,Mahajan P,Frazier AL

    更新日期:2020-08-01 00:00:00

  • Histopathologic behavior of endometrial hyperplasia during tamoxifen therapy for breast cancer.

    abstract:OBJECTIVE:The purpose of the present study is to prospectively evaluate the effects of tamoxifen on the pathological behavior of endometrial hyperplasias without atypia, diagnosed before the start of adjuvant endocrine therapy, in menopausal patients suffering from breast cancer. METHODS:Twenty-six patients suffering ...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Garuti G,Cellani F,Centinaio G,Sita G,Nalli G,Luerti M

    更新日期:2006-05-01 00:00:00

  • Human papillomavirus genotype distribution in cervical cancer cases in Spain. Implications for prevention.

    abstract:OBJECTIVE:Human papillomavirus (HPV) genotype distribution in invasive cervical cancer (ICC) is critical to guide the introduction and to assess the impact of HPV prophylactic vaccines. This study aims to provide specific information for Spain. METHODS:1043 histological confirmed ICC cases diagnosed from 1940 to 2007 ...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章,多中心研究


    authors: Alemany L,Pérez C,Tous S,Llombart-Bosch A,Lloveras B,Lerma E,Guarch R,Andújar M,Pelayo A,Alejo M,Ordi J,Klaustermeier J,Velasco J,Guimerà N,Clavero O,Castellsagué X,Quint W,Muñoz N,Bosch FX,de Sanjosé S,Spanish st

    更新日期:2012-03-01 00:00:00

  • Intraperitoneal chemotherapy following neoadjuvant chemotherapy and optimal interval tumor reductive surgery for advanced ovarian cancer.

    abstract:OBJECTIVES:Intraperitoneal (IP) chemotherapy following neoadjuvant chemotherapy (NACT) and interval tumor reductive surgery (TRS) for advanced ovarian cancer is feasible, however, the impact on disease outcomes remains unclear. We compare outcomes of patients treated with IP chemotherapy versus intravenous (IV) chemoth...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Bixel K,Vetter M,Davidson B,Berchuck A,Cohn D,Copeland L,Fowler JM,Havrilesky L,Lee PS,O'Malley DM,Salani R,Valea F,Alvarez Secord A,Backes F

    更新日期:2020-03-01 00:00:00

  • A multicenter evaluation of adjuvant therapy in women with optimally resected stage IIIC endometrial cancer.

    abstract:OBJECTIVE:To determine if there is an advantage to combination chemotherapy and radiation for optimally resected stage IIIC endometrial cancer (EC). METHODS:A multicenter retrospective analysis of patients with EC from 1991 to 2008 was conducted. Inclusion criteria were lymph node assessment and optimally resected dis...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章,多中心研究


    authors: Secord AA,Geller MA,Broadwater G,Holloway R,Shuler K,Dao NY,Gehrig PA,O'Malley DM,Finkler N,Havrilesky LJ

    更新日期:2013-01-01 00:00:00

  • Prognostic significance of peritoneal cytology in low-intermediate risk endometrial cancer.

    abstract:OBJECTIVES:There is uncertainty surrounding the prognostic value and clinical utility of peritoneal cytology in endometrial cancer. Our primary objective was to determine if positive cytology is associated with disease-free and overall survival in women treated surgically for endometrial cancer, specifically those with...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Scott SA,van der Zanden C,Cai E,McGahan CE,Kwon JS

    更新日期:2017-05-01 00:00:00

  • Treatment of malignant ascites with allogeneic and autologous lymphokine-activated killer cells.

    abstract::Two cases of peritonitis carcinomatosa with gynecological cancer, which did not respond to conventional treatment, were treated by intraperitoneal adoptive immunotherapy with allogeneic or autologous lymphokine-activated killer (LAK) cells plus interleukin-2. In case 1, reduction of acute ascites and disappearance of ...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Kamada M,Sakamoto Y,Furumoto H,Mori K,Daitoh T,Irahara M,Aono T,Nii A,Yanagawa H,Sone S

    更新日期:1989-07-01 00:00:00

  • First-line treatment regimens and the role of consolidation therapy in advanced ovarian cancer.

    abstract::Current first-line management for advanced ovarian cancer consists of cytoreductive surgery followed by chemotherapy, usually with a platinum/taxane combination. Although this approach has been shown to achieve overall response rates of 70-80% in clinical trials, the majority of patients relapse. A number of different...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章,评审


    authors: Stuart GC

    更新日期:2003-09-01 00:00:00

  • Isolated vaginal recurrences in endometrial carcinoma: treatment results using high-dose-rate intracavitary brachytherapy and external beam radiotherapy.

    abstract:PURPOSE:To evaluate the long-term disease control, survival and complication rates using high-dose-rate intracavitary brachytherapy (HDRB) and external beam radiotherapy (EBRT) for patients found to have isolated vaginal recurrences from early-stage endometrial adenocarcinoma following total abdominal hysterectomy and ...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章,评审


    authors: Pai HH,Souhami L,Clark BG,Roman T

    更新日期:1997-08-01 00:00:00

  • Wee1 is a novel independent prognostic marker of poor survival in post-chemotherapy ovarian carcinoma effusions.

    abstract:OBJECTIVE:Wee1-like kinase (Wee1) is a tyrosine kinase which negatively regulates entry into mitosis at the G2 to M-phase transition and has a role in inhibition of unscheduled DNA replication in S-phase. The present study investigated the clinical role of Wee1 in advanced-stage (FIGO III-IV) ovarian serous carcinoma. ...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Slipicevic A,Holth A,Hellesylt E,Tropé CG,Davidson B,Flørenes VA

    更新日期:2014-10-01 00:00:00

  • Endometrial cancer and abdominal wound recurrence.

    abstract::A 65-year-old woman had a total abdominal hysterectomy and bilateral salpingo-oophorectomy through a Pfannenstiel incision for a Stage Ib, Grade 2 endometrial adenocarcinoma with extension to the middle third of the myometrium. No adjuvant treatment was given. She presented 7 years later with a large suprapubic mass a...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Kotwall CA,Kirkbride P,Zerafa AE,Murray D

    更新日期:1994-06-01 00:00:00

  • Clear cell carcinoma of the ovary: a study of 59 cases.

    abstract::Clear cell carcinoma of the ovary accounts for 2 to 3% of all epithelial ovarian neoplasms. Patient profiles, pathological characteristics, and results of treatment are reviewed for 59 patients. The median age was 51. Disease extent at diagnosis was as follows: stage I, 18 patients (31%); stage II, 20 patients (34%); ...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Crozier MA,Copeland LJ,Silva EG,Gershenson DM,Stringer CA

    更新日期:1989-11-01 00:00:00

  • Prognostic significance of hysteroscopic imaging in endometrioid endometrial adenocarcinoma.

    abstract:OBJECTIVE:The aim of this study was to relate hysteroscopic features of endometrioid endometrial adenocarcinoma to stage, grade and overall survival. METHODS:Sixty women with endometrioid adenocarcinoma underwent laparotomy and staging according to current FIGO classification. Before surgery hysteroscopy was performed...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Garuti G,De Giorgi O,Sambruni I,Cellani F,Luerti M

    更新日期:2001-06-01 00:00:00

  • Risk-prediction model of severe postoperative complications after primary debulking surgery for advanced ovarian cancer.

    abstract:OBJECTIVES:To refine models to predict surgical morbidity and 90-day mortality after primary debulking surgery (PDS) for advanced epithelial ovarian cancer (EOC). METHODS:Women with stage IIIC/IV EOC who underwent PDS with curative intent between 1/2/2003 and 12/30/2011 were included. Patient characteristics, intraope...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Kumar A,Janco JM,Mariani A,Bakkum-Gamez JN,Langstraat CL,Weaver AL,McGree ME,Cliby WA

    更新日期:2016-01-01 00:00:00

  • Does para-aortic irradiation reduce the risk of distant metastasis in advanced cervical cancer? A systematic review and meta-analysis of randomized clinical trials.

    abstract:PURPOSE:To evaluate the impact of the extension of the radiotherapy field cranially toward para-aortic lymph nodes (EF-RT) in advanced cervical cancer. MATERIALS AND METHODS:A systematic search of databases (PubMed, CENTRAL, Clinical Trials) was performed and included studies that were published between 1960 and Novem...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章,meta分析,评审


    authors: Sapienza LG,Gomes MJL,Calsavara VF,Leitao MM Jr,Baiocchi G

    更新日期:2017-02-01 00:00:00

  • CO2 laser therapy for cervical intraepithelial neoplasia.

    abstract::One hundred and fifty-six patients with cervical intraepithelial neoplasia (CIN) were treated with CO2 laser and followed for 2 1/2 to 6 years. There were 19 recurrences, of which 14 occurred in patients treated with a power density of less than 1000 W/cm2 to a depth of 6 mm. All of the recurrences were subjected to a...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Caglar H,Ayhan A,Hreshchyshyn MM

    更新日期:1985-09-01 00:00:00

  • Fertility-sparing surgery for treatment of non-epithelial ovarian cancer: Oncological and reproductive outcomes in a prospective nationwide population-based cohort study.

    abstract:OBJECTIVE:To compare the oncologic outcome of women who underwent fertility-sparing surgery (FSS) vs. radical surgery (RS) for treatment of NEOC in a prospective, nationwide, population-based study and report on the reproductive outcomes in women after FSS. METHODS:Using the Swedish Quality Register for Gynecological ...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章,多中心研究


    authors: Johansen G,Dahm-Kähler P,Staf C,Flöter Rådestad A,Rodriguez-Wallberg KA

    更新日期:2019-11-01 00:00:00

  • The prognostic significance of peritoneal seeding and size of postsurgical residual in patients with stage III epithelial ovarian cancer treated with surgery, chemotherapy, and high-dose radiotherapy.

    abstract:OBJECTIVE:The aim of this study was to retrospectively analyze the prognostic importance of age, histologic type and grade, ascites, lymph node status, size and type of postoperative residual disease, and radiation dose on disease-specific (DSS) and progression-free survival (PFS) in stage III epithelial ovarian cancer...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Kapp KS,Kapp DS,Poschauko J,Stücklschweiger GF,Hackl A,Pickel H,Petru E,Winter R

    更新日期:1999-09-01 00:00:00

  • Anti-Yo positive paraneoplastic cerebellar degeneration associated with ovarian carcinoma: case report and review of the literature.

    abstract::Paraneoplastic cerebellar degeneration (PCD) is a rare nonmetastatic neurological complication in cancer patients. Anti-Yo is one of the anti-onconeural antibodies found in PCD patients. It is believed that anti-Yo occurs almost always in women and is most likely associated with gynecologic or breast cancers, although...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章,评审


    authors: Cao Y,Abbas J,Wu X,Dooley J,van Amburg AL

    更新日期:1999-10-01 00:00:00

  • Intraoperative hypothermia during primary surgical cytoreduction for advanced ovarian cancer: risk factors and associations with postoperative morbidity.

    abstract:OBJECTIVE:The objective of this study was to evaluate the risk factors and potential morbidity associated with intraoperative hypothermia (IH) during cytoreductive surgery (CRS) for advanced ovarian cancer. METHODS:Demographic and perioperative data were collected for all patients with stage IIIC-IV ovarian, fallopian...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Long KC,Tanner EJ,Frey M,Leitao MM Jr,Levine DA,Gardner GJ,Sonoda Y,Abu-Rustum NR,Barakat RR,Chi DS

    更新日期:2013-12-01 00:00:00

  • Skull metastasis in primary vulvar adenocarcinoma of the Bartholin's gland: a case report.

    abstract:BACKGROUND:Metastatic bone involvement in vulvar squamous carcinoma is very rare. Here, we present a case of primary adenocarcinoma of the Bartholin's gland giving rise to isolated skull metastasis. CASE:A 74-year-old woman was referred with a diagnosis of primary vulvar adenocarcinoma of the right labium minus. A rig...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Ferrandina G,Testa AC,Zannoni GF,Poerio A,Scambia G

    更新日期:2005-08-01 00:00:00

  • The timing of normalization of CA-125 levels during primary chemotherapy is predictive of survival in patients with epithelial ovarian cancer.

    abstract:OBJECTIVE:To determine if the timing of normalization of CA-125 levels during primary chemotherapy for epithelial ovarian cancer (EOC) could predict survival. METHODS:Patients who reached a complete clinical response for EOC with primary taxane/platinum-based chemotherapy were eligible. Patient demographics, chemother...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Rocconi RP,Matthews KS,Kemper MK,Hoskins KE,Huh WK,Straughn JM Jr

    更新日期:2009-08-01 00:00:00

  • The prognostic significance of the size of the largest nodes in metastatic carcinoma from the uterine cervix.

    abstract::Sizes of the largest metastatic nodes were evaluated as a prognostic factor in 152 patients with Stage IB to IIB cervical carcinomas treated by radical hysterectomy and postoperative irradiation. Of the 152 cases, the largest positive nodes were less than 10 mm in 24 (16%), 10-20 mm in 74 (49%), greater than or equal ...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Inoue T,Chihara T,Morita K

    更新日期:1984-10-01 00:00:00

  • Phase II trial of CI-958 in recurrent platinum-refractory ovarian carcinoma. A Gynecologic Oncology Group Study.

    abstract:OBJECTIVES:The objectives of this study were twofold: (1) to estimate the anti-tumor efficacy of CI-958 in patients with measurable platinum-resistant ovarian cancer; (2) to determine the nature and degree of toxicity of CI-958 in these patients. METHODS:Patients received CI-958 560 mg/m(2) intravenously every 3 weeks...

    journal_title:Gynecologic oncology

    pub_type: 临床试验,杂志文章,多中心研究


    authors: Hoffman MA,Blessing JA,Morgan M

    更新日期:2000-12-01 00:00:00

  • Intraepithelial neoplasia in the vulvar region.

    abstract::From 1978 to 1982, 49 patients with intraepithelial neoplasia in the vulvar region were included in a prospective investigation. The main purpose was to evaluate the effect of treatment by local excision with a free margin of 2 mm and to estimate the importance of colposcopy. In 28% of the patients, the disease recurr...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Andreasson B,Bock JE

    更新日期:1985-07-01 00:00:00

  • Urokinase (uPA) and PAI-1 predict survival in advanced ovarian cancer patients (FIGO III) after radical surgery and platinum-based chemotherapy.

    abstract::Fifty-one patients with advanced ovarian cancer FIGO III were studied to determine new tumor biology-oriented prognostic factors. The tumor-associated protease urokinase-type plasminogen activator (uPA) and its inhibitor PAI-1 were detected in malignant ovarian cancer tissue extracts. The concentration of both factors...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Kuhn W,Pache L,Schmalfeldt B,Dettmar P,Schmitt M,Jänicke F,Graeff H

    更新日期:1994-12-01 00:00:00

  • An ultrastructural comparison of grade I and II endometrial adenocarcinoma considering estrogen and progesterone receptor status.

    abstract::Eighteen (18) previously untreated patients with grade I (9) and II (9) endometrial adenocarcinoma provided endometrial samples for biochemical analysis of estrogen and progesterone receptors. The same samples were evaluated by histology and ultrastructure. Progesterone receptor negative samples (PR less than 1000 fmo...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Horbelt DV,Freedman RS,Roberts DK,Walker NJ,Edwards CL,Jones LA

    更新日期:1984-06-01 00:00:00

  • Toward understanding the natural history of ovarian carcinoma development: a clinicopathological approach.

    abstract:OBJECTIVE:The natural history of the development of ovarian carcinoma is not known. It also remains undetermined whether ovarian carcinomas develop from benign and/or borderline malignant tumors or arise de novo from the ovarian surface epithelium. METHODS:To address these issues clinicopathologically, we reviewed the...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章,多中心研究


    authors: Horiuchi A,Itoh K,Shimizu M,Nakai I,Yamazaki T,Kimura K,Suzuki A,Shiozawa I,Ueda N,Konishi I

    更新日期:2003-03-01 00:00:00

  • Risk-specific follow-up for endometrial carcinoma patients.

    abstract:OBJECTIVE:To propose a risk-specific follow-up protocol for endometrial carcinoma patients. METHODS:A retrospective cohort of endometrial carcinoma patients was used to identify risk factors for recurrence. Based on a profile of risk factors, women were classified at either low or high risk for recurrence (median foll...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章


    authors: Shumsky AG,Brasher PM,Stuart GC,Nation JG

    更新日期:1997-06-01 00:00:00

  • The accuracy of magnetic resonance imaging in staging of vulvar cancer: a retrospective multi-centre study.

    abstract:OBJECTIVE:To retrospectively evaluate the diagnostic accuracy and clinical relevance of magnetic resonance imaging (MRI) in the management of primary and recurrent vulvar cancer and to examine the added value of contrast-enhanced MRI (CE-MRI). METHODS:The research ethics committee waived informed consent for this stud...

    journal_title:Gynecologic oncology

    pub_type: 杂志文章,多中心研究


    authors: Kataoka MY,Sala E,Baldwin P,Reinhold C,Farhadi A,Hudolin T,Hricak H

    更新日期:2010-04-01 00:00:00