Abstract:
:Immunohistochemical techniques were used to survey the distribution of several conventional transmitters, receptors, and neuropeptides in the pigeon nucleus of the basal optic root (nBOR), a component of the accessory optic system. Amongst the conventional neurotransmitters/modulators, the most intense labeling of fibers/terminals within the nBOR was obtained with antisera directed against glutamic acid decarboxylase (GAD) and serotonin (5-HT). Moderately dense fiber plexuses were seen to label with antibodies directed against tyrosine hydroxylase (TH) and choline acetyltransferase (ChAT). GAD-like immunoreactivity (GAD-LI) was found in many small and medium-sized perikarya within the nBOR. Some of the medium-sized cells were occasionally positive for ChAT-LI. Cell body and dendritic staining was also commonly seen with the two tested antisera against receptors-anti-GABA-A receptor and anti-nicotinic acetylcholine receptor. The antisera directed against various neuropeptides produced only fiber labeling within the nBOR. The densest fiber plexus staining was observed with antiserum against neuropeptide Y (NPY-LI), while intermediate fiber densities were seen for substance P (SP-LI) and cholecystokinin (CCK-LI). A few varicose fibers were labeled with antisera against neurotensin (NT), leucine-enkephalin (L-ENK), and the vasoactive intestinal polypeptide (VIP). Unilateral enucleation produced an almost complete elimination of TH-LI in the contralateral nBOR. SP-LI and CCK-LI were also decreased after enucleation. No apparent changes were seen for all other substances. These results indicate that a wide variety of chemically-specific systems arborize within the nBOR. Three of the immunohistochemically defined fiber systems (TH-LI, SP-LI, and CCK-LI fibers) were reduced after removal of the retina, which may indicate the presence of these substances in retinal ganglion cells. In contrast, the fibers exhibiting ChAT-LI, GAD-LI, 5-HT-LI, NPY-LI, NT-LI, L-ENK-LI, and VIP-LI appear to be of nonretinal origin. Two different populations of nBOR neurons exhibited GAD-LI and ChAT-LI. However, these two populations together constituted only about 20% of the nBOR neurons.
journal_name
Vis Neuroscijournal_title
Visual neuroscienceauthors
Britto LR,Hamassaki DE,Keyser KT,Karten HJdoi
10.1017/s0952523800005964subject
Has Abstractpub_date
1989-11-01 00:00:00pages
463-75issue
5eissn
0952-5238issn
1469-8714pii
S0952523800005964journal_volume
3pub_type
杂志文章abstract::We examine the assumptions that the fovea contains equal numbers of inner (invaginating or ON) and outer (flat or OFF) midget bipolar cells and equal numbers of inner and outer diffuse bipolar cells. Based on reconstruction from electron photomicrographs of serial thin sections through the fovea of a macaque monkey, w...
journal_title:Visual neuroscience
pub_type: 杂志文章
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更新日期:2003-03-01 00:00:00
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journal_title:Visual neuroscience
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doi:10.1017/s0952523800007537
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journal_title:Visual neuroscience
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journal_title:Visual neuroscience
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doi:10.1017/S0952523808080851
更新日期:2008-09-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/S0952523806231055
更新日期:2006-01-01 00:00:00
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journal_title:Visual neuroscience
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更新日期:2004-07-01 00:00:00
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journal_title:Visual neuroscience
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更新日期:2001-03-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
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journal_title:Visual neuroscience
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更新日期:1993-09-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800174012
更新日期:2000-07-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800005496
更新日期:1989-10-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800001735
更新日期:1994-03-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s095252380118404x
更新日期:2001-07-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800175042
更新日期:2000-09-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
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更新日期:1995-01-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/S0952523807070393
更新日期:2007-03-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800011512
更新日期:1997-03-01 00:00:00
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journal_title:Visual neuroscience
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更新日期:1999-09-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章,评审
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更新日期:1991-01-01 00:00:00
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更新日期:2006-05-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s095252380000403x
更新日期:1991-09-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800000341
更新日期:1990-09-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800007975
更新日期:1995-03-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800012578
更新日期:1997-07-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800004582
更新日期:1990-04-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
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更新日期:2002-11-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
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更新日期:2007-09-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
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更新日期:1998-01-01 00:00:00