Performance of Aneurysm Wall Enhancement Compared with Clinical Predictive Scales: PHASES, ELAPSS, and UIATS.


OBJECTIVE:To correlate the presence of objectively measured wall enhancement on high-resolution vessel wall imaging (HR-VWI) with the clinical predictive scales PHASES, ELAPSS, and UIATS. METHODS:Patients with unruptured intracranial aneurysm (UIAs) prospectively underwent HR-VWI on a 3-T magnetic resonance imaging scanner at diagnosis. Aneurysmal wall enhancement was objectively quantified on T1 postcontrast magnetic resonance imaging using signal intensity values adjusted for the pituitary stalk to calculate a contrast ratio (CRstalk). UIAs with CRstalk ≥0.60 were considered "enhancing." Patients' demographics, comorbidities, and aneurysm morphology were reviewed to calculate PHASES, ELAPSS, and UIATS scores. Pearson coefficients were applied for statistical correlation. Univariable and multivariable logistic regressions were performed to assess for confounders. RESULTS:One-hundred and twenty-three patients harboring 178 UIAs underwent HR-VWI. A total of 101 patients with 135 UIAs were analyzed. Enhancing UIAs were larger (8.4 ± 5.5 mm vs. 5.5 ± 2.3 mm; P < 0.001), had higher aspect ratio (2.3 ± 1.5 vs. 1.8 ± 0.7; P = 0.008), higher size ratio (3.0 ± 1.8 vs. 2.4 ± 1.1; P = 0.016), scored higher on PHASES (5.6 ± 3.9 vs. 4.4 ± 2.6; P = 0.04) and ELAPSS (19.4 ± 8.9 vs. 15.4 ± 7.3; P = 0.006) compared with nonenhancing UIAs. Treatment allocation as defined by UIATS was measured independently to enhancement status. No significant differences were found for UIATS between enhancing and nonenhancing UIAs (P = 0.63). Multivariable regression showed that size was the only independent factor significantly associated with UIA enhancement (odds ratio, 1.76; P = 0.005). CONCLUSIONS:Enhancing UIAs score higher in PHASES and ELAPSS scales. This association is largely explained by aneurysm size, aspect, and size ratios. Morphologic UIA features should be accounted for in clinical predictive scales of aneurysm instability.


World Neurosurg


World neurosurgery


Roa JA,Sabotin RP,Varon A,Raghuram A,Patel D,Morris TW,Ishii D,Lu Y,Hasan DM,Samaniego EA




Has Abstract


2020-12-31 00:00:00








  • The Foundation for International Education in Neurological Surgery.

    abstract::The Foundation for International Education in Neurological Surgery (FIENS) was established in 1969 for the purpose of promoting neurosurgical education and patient care in the developing world. Ghana, the first African site, was adopted in 1989. In 2005 a neurosurgical training program was developed for Ethiopia, Keny...

    journal_title:World neurosurgery

    pub_type: 历史文章,杂志文章


    authors: Bagan M

    更新日期:2010-04-01 00:00:00

  • Identifying the Geographic Profile of International Visitors to the United States for Neurosurgical Education: A Single Institution's Experience.

    abstract:BACKGROUND:Departments of neurosurgery in the United States have had a long history of hosting international visitors for the advancement of their neurosurgical education. The goal of the present study was to determine the existence of a geographic profile of international visitors for education purposes, both students...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Lu VM,Scheitler K,Perry A,Graffeo CS,Carlstrom LP,Daniels DJ,Meyer FB

    更新日期:2020-07-01 00:00:00

  • To Drain or Two Drains: Recurrences in Chronic Subdural Hematomas.

    abstract:BACKGROUND:Chronic subdural hematoma (cSDH) is a common neurosurgical condition, with an estimated incidence of 3-15.5 per 100,000 people, with significantly higher rates in the elderly population. Recurrence rates range from 2%-37% after surgical drainage. Studies have shown that leaving a drain postoperatively can re...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Gernsback J,Kolcun JP,Jagid J

    更新日期:2016-11-01 00:00:00

  • Endovascular Treatment Versus Best Medical Therapy in Acute Ischemic Stroke Patients with Mild Symptoms.

    abstract:BACKGROUND:The benefit of endovascular treatment (EVT) for acute ischemic stroke patients with mild deficits is unknown. We sought to evaluate the natural history of patients with a low National Institute of Health Stroke Score (NIHSS) and an intracranial occlusion. METHODS:We included patients with a computed tomogra...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Nicholson P,Byun JS,Lu H,Hilditch CA,Brinjikji W,Agid R,Casaubon LK,Krings T,Schaafsma JD,Mendes-Pereira V

    更新日期:2020-12-01 00:00:00

  • Pictorial review of in vivo human brain: from anatomy to molecular imaging.

    abstract::Recent advances in neuroimaging demonstrated many markedly improved images hitherto unavailable, specifically the areas that lie deep in the brain. The anatomic images of the deep brain structure taken in vivo using 7.0 T magnetic resonance imaging (MRI) and the molecular images using high resolution research tomograp...

    journal_title:World neurosurgery

    pub_type: 杂志文章,评审


    authors: Cho ZH,Kang CK,Son YD,Choi SH,Lee YB,Paek SH,Park CW,Chi JG,Calamante F,Law M,Kim YB

    更新日期:2014-07-01 00:00:00

  • Arterial Sling Decompression for Hemifacial Spasm.

    abstract::Hemifacial spasm is a cranial nerve compression syndrome caused by impingement on the facial nerve most frequently by the anterior inferior cerebellar artery or the posterior inferior cerebellar artery. It can be treated with microvascular decompression (MVD) to separate the nerve from the offending artery. Rarely, a ...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Jha RT,Kumar J,Pressman E,Agazzi S

    更新日期:2019-12-01 00:00:00

  • Surgical Techniques and Associated Outcomes of Primary Chondrosarcoma of the Spine.

    abstract:BACKGROUND:Only a few case reports and case series exist reporting on primary chondrosarcomas of the spine. The objective of this study was to gain a better understanding of this patient population and surgical techniques used for treatment. METHODS:A systematic literature search was performed in January 2018 querying...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Nisson PL,Berger GK,James WS,Hurlbert RJ

    更新日期:2018-11-01 00:00:00

  • Endoscopic Endonasal Approach for Craniovertebral Junction Pathologic Conditions: Myth and Truth in Clinical Series and Personal Experience.

    abstract:OBJECTIVE:For many years, the microsurgical transoral approach has been accepted as the gold standard for anterior decompressions of the craniovertebral junction (CVJ). The introduction of the endoscopic endonasal approach (EEA) has gained wide recognition and overwhelming support in recent years, including for disease...

    journal_title:World neurosurgery

    pub_type: 杂志文章,评审


    authors: Visocchi M,Signorelli F,Liao C,Rigante M,Paludetti G,Barbagallo G,Olivi A

    更新日期:2017-05-01 00:00:00

  • MRI Prognostication Factors in the Setting of Cervical Spinal Cord Injury Secondary to Trauma.

    abstract:OBJECTIVE:Several studies have looked for an association between radiologic findings and neurologic outcome after cervical trauma. In the current literature, there is a paucity of evidence proving the prognostic role of soft tissue damage or bony integrity. Our objective is to determine radiologic findings related to n...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Martínez-Pérez R,Cepeda S,Paredes I,Alen JF,Lagares A

    更新日期:2017-05-01 00:00:00

  • Rosiglitazone Infusion Therapy Following Minimally Invasive Surgery for Intracranial Hemorrhage Evacuation Decreased Perihematomal Glutamate Content and Blood-Brain Barrier Permeability in Rabbits.

    abstract:OBJECTIVE:To observe effects of rosiglitazone (RSG) infusion therapy on perihematomal peroxisome-proliferator-activated receptor gamma (PPARγ), glutamate, blood-brain barrier (BBB) permeability, and brain edema. METHODS:Fifty male rabbits (2.8-3.4 kg) were randomly assigned to a normal control (NC) group, model contro...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Wu G,Jiao Y,Wu J,Ren S,Wang L,Tang Z,Zhou H

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  • Subtemporal approach to posterior cerebral artery aneurysms.

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    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Goehre F,Lehecka M,Jahromi BR,Lehto H,Kivisaari R,Hijazy F,Nayeb L,Sugimoto T,Morishige M,Elsharkawy A,von und zu Fraunberg M,Jääskeläinen JE,Hernesniemi JA

    更新日期:2015-05-01 00:00:00

  • Readability of Online Neuro-Oncology-Related Patient Education Materials from Tertiary-Care Academic Centers.

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    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Ammanuel SG,Edwards CS,Alhadi R,Hervey-Jumper SL

    更新日期:2020-02-01 00:00:00

  • Turbulent Cerebrospinal Fluid Flow in Enlarging Terminal Myelocystocele.

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    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Sprenger F,de Andrade JMC,de Almeida Teixeira BC

    更新日期:2020-12-19 00:00:00

  • Brainstem tethering with Ondine's curse.

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    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Liu Z,He Y,Li S,Wu L,Jiao Q

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  • Posterior Lumbar Interbody Fusion versus Dynamic Hybrid Instrumentation: A Prospective Randomized Clinical Trial.

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    journal_title:World neurosurgery

    pub_type: 杂志文章,随机对照试验


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  • AOSpine Subaxial Cervical Spine Injury Classification System: The Relationship Between Injury Morphology, Admission Injury Severity, and Long-Term Neurologic Outcome.

    abstract:OBJECTIVE:The AOSpine Subaxial Cervical Spine Injury Classification System was introduced to improve communication, clinical management, and research. Here, the system was studied in relation to injury severity along with admission and long term neurologic follow-up. METHODS:A retrospective study was performed in suba...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Mushlin H,Kole MJ,Chryssikos T,Cannarsa G,Schwartzbauer G,Aarabi B

    更新日期:2019-10-01 00:00:00

  • Microvascular Fluorescence in Spinal Cord Repair.

    abstract::The release of the placode and reconstruction of the myelomeningocele, preserving the maximum neural tissue is a challenge for the neurosurgeon. Vascular fluorescence with indocyanine green and/or fluorescein allows observation of the microvascularization of the spinal cord and adequately identifies viable tissue. ...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Mayorga-Buiza MJ,Rivero-Garvia M,Márquez-Rivas J

    更新日期:2019-05-01 00:00:00

  • Far Lateral Approach for In Situ Occlusion of Craniospinal Cervicomedullary Arteriovenous Malformation Presenting with Subarachnoid Hemorrhage.

    abstract::A 49-year-old woman presented with sudden-onset headache and meningismus. Computed tomography scan revealed a posterior fossa subarachnoid hemorrhage extending from the foramen magnum to the ambient cistern. Angiography showed a pial extramedullary arteriovenous malformation (AVM) at the lateral ventral surface of the...

    journal_title:World neurosurgery



    authors: Rodriguez Rubio R,Raper D,Zhu H,Abla AA

    更新日期:2020-07-01 00:00:00

  • Ankylosing Spondylitis Manifested by Extensive Cervical Erosions with Spontaneous Anterior Atlantoaxial Subluxation.

    abstract:BACKGROUND:Atlantoaxial instability owing to bone erosions in a patient with ankylosing spondylitis (AS) is rare. We describe the radiographic characteristics, pathology, and treatment of a patient with this rare clinical manifestation and review the literature. CASE DESCRIPTION:A 36-year-old man with an 8-year histor...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Liu J,Zhu L,Jiang E,Zou S,Xu G

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  • Usefulness of High-Resolution Three-Dimensional Multifusion Medical Imaging for Preoperative Planning in Patients with Cerebral Arteriovenous Malformation.

    abstract:BACKGROUND:Successful resection of arteriovenous malformation (AVM) depends on preoperative assessment of the detailed morphology of the AVM. Simultaneous detailed three-dimensional visualization of the feeding arteries, draining veins, and surrounding structures is needed. The aim of this study was to evaluate the use...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Yoshino M,Kin T,Hara T

    更新日期:2019-01-22 00:00:00

  • Occipital Artery to Anterior Inferior Cerebellar Artery (AICA) Bypass for Treatment of a Ruptured Proximal AICA-Posterior Inferior Cerebellar Artery Mycotic Aneurysm.

    abstract:BACKGROUND:Intracranial mycotic aneurysms are uncommon. They can occur due to extravascular extension or intravascular seeding of the vessel wall. They often result in subarachnoid hemorrhage with poor prognosis. We present a rare case of subarachnoid hemorrhage due to vertebral artery dissection with aproximal anterio...

    journal_title:World neurosurgery



    authors: Aljuboori Z,Ding D,Andaluz N

    更新日期:2020-10-01 00:00:00

  • Morbidities Associated with the Endoscopic Transnasal Transpterygoid Approach: Focusing on Postoperative Sequelae.

    abstract:OBJECTIVE:Although the endoscopic transpterygoid approach has been popularized, there are no studies about anatomy-specific morbidities of this approach. The objective of this study is to investigate the surgical morbidities associated with the endoscopic transpterygoid approach for resection of anatomic structures. M...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Choi JE,Noh YS,Lee KE,Jung YG,Chung SK,Kim HY,Kong DS,Nam DH,Hong SD

    更新日期:2020-05-01 00:00:00

  • Outpatient Lumbar Microdiscectomy in France: From an Economic Imperative to a Clinical Standard-An Observational Study of 201 Cases.

    abstract:PURPOSE:The outpatient lumbar discectomy procedures have been established for more than 2 decades. However, especially in Europe, there are still obstacles to the development of these procedures, which may be related to medicoeconomic imperatives, and to several factors concerning both surgeons and patients. We describ...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Debono B,Sabatier P,Garnault V,Hamel O,Bousquet P,Lescure JP,Plas JY

    更新日期:2017-10-01 00:00:00

  • Nuances in Localization and Surgical Treatment of Syringomyelia Associated with Fenestrated and Webbed Intradural Spinal Arachnoid Cyst: A Retrospective Analysis.

    abstract:INTRODUCTION:Intradural spinal arachnoid cysts (SACs) are among many etiologies for syringomyelia. Consequentially, neurologic symptoms arise such as pain, gait disturbance, and bladder dysfunction. Identification of SAC on magnetic resonance imaging (MRI) can be challenging, as SACs can be fenestrated or in the form o...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Srinivasan VM,Fridley JS,Thomas JG,Omeis I

    更新日期:2016-03-01 00:00:00

  • Transorbital Ultrasonographic Measurement of Optic Nerve Sheath Diameter for Intracranial Midline Shift in Patients with Head Trauma.

    abstract:OBJECTIVE:Measurement of the optic nerve sheath diameter (ONSD) by using sonography is a straightforward, noninvasive technique to detect an increased intracranial pressure, which can even be conducted at the bedside. However, the correlation between ONSD and intracranial midline shift has not been studied. METHODS:Th...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Kazdal H,Kanat A,Findik H,Sen A,Ozdemir B,Batcik OE,Yavasi O,Inecikli MF

    更新日期:2016-01-01 00:00:00

  • Limb Undergrowth in Intraneural Perineuriomas: An Under-Recognized Association.

    abstract:BACKGROUND:Intraneural (IN) perineuriomas are a rare benign hypertrophic nerve tumor, most frequently occurring in young patients. Patients with IN perineurioma have been anecdotally found to have limb undergrowth; however, this has not been systematically evaluated. METHODS:Archived electronic records from 1990 to 20...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Pendleton C,Lenartowicz KA,Howe BM,Spinner RJ

    更新日期:2020-09-01 00:00:00

  • Academic Productivity of Neurosurgeons Working in the United Kingdom: Insights from the H-Index and Its Variants.

    abstract:OBJECTIVES:Academic metrics can be used to compare the productivity of researchers. We aimed to use a variety of bibliometric parameters to assess the productivity of neurosurgeons working in the United Kingdom. METHODS:Neurosurgical consultants working in the United Kingdom were identified using the Society of Britis...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Jamjoom AA,Wiggins AN,Loan JJ,Emelifeoneu J,Fouyas IP,Brennan PM

    更新日期:2016-02-01 00:00:00

  • Transforaminal Resection of Cervical Dumbbell Schwannomas in Patients with Additional Tumors.

    abstract:BACKGROUND:It is rare for 2 primary tumors to occur simultaneously in a patient. Management of cervical dumbbell schwannomas (CDSs) with concurrent tumors (CTs) requires a specific neurosurgical strategy. The primary objective of this study is to investigate surgical strategies for CDSs with CTs while preserving as muc...

    journal_title:World neurosurgery

    pub_type: 杂志文章,多中心研究


    authors: Zhang J,Zhang XH,Wang ZF,Li YP,Zhu ZQ,Sun JC,Chen ZH,Wu SY,Sai K,Wang J,Mou YG,Chen ZP

    更新日期:2017-02-01 00:00:00

  • External Validation of Scoring Models to Predict Shunt Insertion after Aneurysmal Subarachnoid Hemorrhage.

    abstract:BACKGROUND:The current study is an external validation of 4 scoring models proposed in the literature for predicting ventriculoperitoneal shunt insertion after aneurysmal subarachnoid hemorrhage (aSAH) using retrospective patient data from Sheffield Teaching Hospital (STH). METHODS:Data were collected on various demog...

    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Vyas D,Booker J,Smith D,Al-Tamimi YZ

    更新日期:2020-12-01 00:00:00

  • Anterior Cervical Discectomy and Fusion Versus Hybrid Decompression and Fusion for the Treatment of 3-Level Cervical Spondylotic Myelopathy: A Comparative Analysis of Cervical Sagittal Balance and Outcomes.

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    journal_title:World neurosurgery

    pub_type: 杂志文章


    authors: Xu Z,Rao H,Zhang L,Li G,Xu Z,Xu W

    更新日期:2019-12-01 00:00:00