Abstract:
:A large economics literature has shown long term impacts of birth weight on adult outcomes, including IQ and earnings that are often robust to sibling or twin fixed effects. We examine potential mechanisms underlying these effects by incorporating findings from the genetics and neuroscience literatures. We use a sample of siblings combined with an "orchids and dandelions hypothesis", where the IQ of genetic dandelions is not affected by in utero nutrition variation but genetic orchids thrive under advantageous conditions and wilt in poor conditions. Indeed, using variation in three candidate genes related to neuroplasticity (APOE, BDNF, and COMT), we find substantial heterogeneity in the associations between birth weight and adult outcomes, where part of the population (i.e., "dandelions") is not affected by birth weight variation. Our results help uncover why birth weight affects adult outcomes.
journal_name
J Health Econjournal_title
Journal of health economicsauthors
Justin Cook C,Fletcher JMdoi
10.1016/j.jhealeco.2015.01.005subject
Has Abstractpub_date
2015-05-01 00:00:00pages
107-16eissn
0167-6296issn
1879-1646pii
S0167-6296(15)00006-5journal_volume
41pub_type
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