Effect of alendronate sodium on tooth movement in ovariectomized rats.

Abstract:

OBJECTIVES:The aim of the present study was to evaluate the effect of two different dosages of alendronate on induced orthodontic movement in an experimental model involving rats with osteoporosis following ovariectomy. DESIGN:Female Wistar rats (Rattus norvegicus) eight weeks of age were divided into four groups (n=12/group): ovariectomized (OVX group); ovariectomized and treated with alendronate sodium at 1mg/kg (Group OVX+ALN1); ovariectomized and treated with alendronate sodium at 2mg/kg (Group OVX+ALN2); and sham operated (control). Three months after ovariectomy, the maxillary right first molar was submitted to movement for five and seven days. After the death of the animals, the maxilla were removed and processed for microscopic evaluation. The maxillary left first molar (without movement) was used for comparison purposes in all groups. The samples were processed for the quantification of alveolar bone and tooth movement. RESULTS:Intragroup comparisons showed significant movement after five and seven days (p<0.05) for all groups. Comparison among groups revealed greater tooth movement in the OVX group (p<0.05), on day 7. CONCLUSIONS:Both alendronate sodium doses similarly decreased tooth movement in ovariectomized rats (p>0.05). Movement in ovariectomized+alendronate groups were also smaller than non-ovariectomized rats, however without statistical difference.

journal_name

Arch Oral Biol

journal_title

Archives of oral biology

authors

Salazar M,Hernandes L,Ramos AL,Salazar Bde O,Micheletti KR,Paranhos LR,de Mendonça MR,Cuoghi OA

doi

10.1016/j.archoralbio.2015.02.003

subject

Has Abstract

pub_date

2015-05-01 00:00:00

pages

776-81

issue

5

eissn

0003-9969

issn

1879-1506

pii

S0003-9969(15)00026-6

journal_volume

60

pub_type

杂志文章
  • The effect of transport-blocking drugs on secretion of fluid and electrolytes by the mandibular gland of red kangaroos, Macropus rufus.

    abstract::Mechanisms of primary fluid formation by macropodine mandibular glands were investigated in anaesthetized red kangaroos using ion-transport and carbonic anhydrase inhibitors. Bumetanide at carotid plasma concentrations of 0.005-0.1 mmol/l progressively reduced a stable, acetylcholine-evoked flow rate of 1.02 +/- 0.024...

    journal_title:Archives of oral biology

    pub_type: 杂志文章

    doi:10.1016/s0003-9969(97)00074-5

    authors: Beal AM

    更新日期:1997-10-01 00:00:00

  • Degradation of human secretory immunoglobulin A by protease isolated from the anaerobic periodontopathogenic bacterium, Bacteroides gingivalis.

    abstract::This bacterium is implicated in periodontal diseases of human adult type. Secretory immunoglobulin A (IgA) purified from human colostrum (HC-IgA) was incubated with Bacteroides gingivalis cells or protease isolated from the culture supernatant of B. gingivalis; the digestion of IgA was determined by immunoelectrophore...

    journal_title:Archives of oral biology

    pub_type: 杂志文章

    doi:10.1016/0003-9969(87)90016-1

    authors: Sato M,Otsuka M,Maehara R,Endo J,Nakamura R

    更新日期:1987-01-01 00:00:00

  • The ultrastructure of the dental tissues in dentinogenesis imperfecta in man.

    abstract::Eight primary incisors obtained from a child with dentinogenesis imperfecta (DI) type II were examined histologically using light microscopy and scanning electron microscopy. In both the DI and control teeth, large dentinal canals were observed along the midline of the crown distributed mesial-distally and coursing to...

    journal_title:Archives of oral biology

    pub_type: 杂志文章

    doi:10.1016/0003-9969(85)90116-5

    authors: Wright JT,Gantt DG

    更新日期:1985-01-01 00:00:00

  • Antibacterial and cytotoxic evaluation of copper and zinc oxide nanoparticles as a potential disinfectant material of connections in implant provisional abutments: An in-vitro study.

    abstract:OBJECTIVE:This study evaluates the antibacterial activity against mono and multispecies bacterial models and the cytotoxic effects of zinc oxide and copper nanoparticles(ZnO-NPs/Cu-NPs) in cell cultures of human gingival fibroblasts(HGFs). DESIGN:The antibacterial activities of ZnO-NPs and Cu-NPs against 4 bacteria sp...

    journal_title:Archives of oral biology

    pub_type: 杂志文章

    doi:10.1016/j.archoralbio.2020.105031

    authors: Vergara-Llanos D,Koning T,Pavicic MF,Bello-Toledo H,Díaz-Gómez A,Jaramillo A,Melendrez-Castro M,Ehrenfeld P,Sánchez-Sanhueza G

    更新日期:2021-02-01 00:00:00

  • Functional influence of masticatory muscles on the fibre characteristics and capillary distribution in growing ferrets (Mustela putonusfuro)--a histochemical analysis.

    abstract:OBJECTIVE:Changes in the masticatory function of ferrets have been shown to cause alterations in their craniofacial morphology. The aim of the present study was to investigate how the functional changes influence the histochemical characteristics of fibres of the masticatory muscles of the animal. DESIGN:Forty five-we...

    journal_title:Archives of oral biology

    pub_type: 杂志文章

    doi:10.1016/j.archoralbio.2004.07.011

    authors: He T,Olsson S,Daugaard JR,Kiliaridis S

    更新日期:2004-12-01 00:00:00

  • Comparison of platelet-rich plasma (PRP), platelet-rich fibrin (PRF), and concentrated growth factor (CGF) in rabbit-skull defect healing.

    abstract:OBJECTIVES:The objective of this study was to evaluate the effect of platelet-rich plasma (PRP), platelet-rich fibrin (PRF), and concentrated growth factor (CGF) on bone healing. STUDY DESIGN:Twelve rabbits were included in this randomized, blinded, prospective study. 15-mm×10-mm-sized defects were created in the pari...

    journal_title:Archives of oral biology

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.archoralbio.2014.02.004

    authors: Kim TH,Kim SH,Sándor GK,Kim YD

    更新日期:2014-05-01 00:00:00

  • PAX9 and MSX1 transcription factor genes in non-syndromic dental agenesis.

    abstract:OBJECTIVE:The molecular variation of paired domain box gene 9 (PAX9) was previously investigated by our research group and a high degree of evolutionary conservation in coding and non-coding regions was observed except in exon 3. PAX9 is a transcription factor important in tooth development, and we wanted to verify its...

    journal_title:Archives of oral biology

    pub_type: 杂志文章

    doi:10.1016/j.archoralbio.2010.10.020

    authors: Paixão-Côrtes VR,Braga T,Salzano FM,Mundstock K,Mundstock CA,Bortolini MC

    更新日期:2011-04-01 00:00:00

  • Effects of NaF and SnF2 on growth, acid and glucan production of several oral streptococci.

    abstract::The effects of low concentrations of these fluorides on Streptococcus sobrinus, Streptococcus mutans, Streptococcus salivarius, Streptococcus mitior and Streptococcus sanguis were investigated. Without fluoride, mutans streptococci (Strep. mutans and Strep. sobrinus) produced more acid than the other strains; both flu...

    journal_title:Archives of oral biology

    pub_type: 杂志文章

    doi:10.1016/0003-9969(87)90007-0

    authors: Zameck RL,Tinanoff N

    更新日期:1987-01-01 00:00:00

  • Analysis of syndecan-1 gene promoter during mouse tooth development.

    abstract:OBJECTIVE:Syndecan-1 plays an important role in cell proliferation in dental papilla during tooth development. This study aimed to clarify the transcription mechanisms that regulate syndecan-1 gene expression in dental papilla. DESIGN:We analysed genomic conservation and putative transcriptional factor binding sites o...

    journal_title:Archives of oral biology

    pub_type: 杂志文章

    doi:10.1016/j.archoralbio.2011.10.017

    authors: Iguchi-Ishiguro H,Ouchi Y,Watanabe S,Numabe Y

    更新日期:2012-05-01 00:00:00

  • An electrophysiological study of the reinnervation of reimplanted and autotransplanted teeth in the cat.

    abstract::There is evidence to suggest that some reimplanted and autotransplanted teeth are reinnervated, but the time-course of reinnervation and the properties and source of the reinnervating axons are not known. This reinnervation has been investigated using electrophysiological techniques in 6 adult cats. In each cat, one l...

    journal_title:Archives of oral biology

    pub_type: 杂志文章

    doi:10.1016/0003-9969(83)90172-3

    authors: Robinson PP

    更新日期:1983-01-01 00:00:00

  • Anti-caries effect of fluoridated milk-based drink consumed by older adults on an in vitro root caries experimental model.

    abstract:OBJECTIVE:This study aimed to evaluate the anti-caries effect of a fluoridated milk-based drink on a root caries model by assessing mineral loss and both biofilm microbial viability and acidogenicity under increasing concentrations of fluoride supplementation. DESIGN:Streptococcus mutans UA159 biofilms were grown on r...

    journal_title:Archives of oral biology

    pub_type: 杂志文章

    doi:10.1016/j.archoralbio.2020.104878

    authors: Castro RJ,Maltz M,Arthur RA,Giacaman RA

    更新日期:2020-10-01 00:00:00

  • Orientation of occlusal contacts in the chimpanzee, Pan troglodytes verus, deduced from scanning electron microscopic analysis of dental microwear patterns.

    abstract::Analysis of dental microwear may be used to detect species differences in diet and to secure information about occlusal relationships and biomechanics of the jaw. Microscratch-orientation data evaluated with reference to several hypotheses about functional, wear-related, sex and age influences on occlusal contacts ind...

    journal_title:Archives of oral biology

    pub_type: 杂志文章

    doi:10.1016/0003-9969(84)90007-4

    authors: Gordon KD

    更新日期:1984-01-01 00:00:00

  • Comparisons of chewing rhythm, craniomandibular morphology, body mass and height between mothers and their biological daughters.

    abstract:OBJECTIVE:To study and compare the relationships between mean chewing cycle duration, selected cephalometric variables representing mandibular length, face height, etc., measured in women and in their teenage or young-adult biological daughters. DESIGN:Daughters were recruited from local high schools and the Universit...

    journal_title:Archives of oral biology

    pub_type: 杂志文章

    doi:10.1016/j.archoralbio.2015.08.004

    authors: Cho C,Louie K,Maawadh A,Gerstner GE

    更新日期:2015-11-01 00:00:00

  • Heat-induced changes in the rat parotid gland.

    abstract::Gland size, amylase activity, total proteins and DNA concentrations were measured in parotid gland during chronic heat exposure (34 degrees C). Subcellular fractionation was performed. Exposure to heat resulted in a decrease in gland size and in DNA concentration; amylase activity/100 mg tissue and amylase specific ac...

    journal_title:Archives of oral biology

    pub_type: 杂志文章

    doi:10.1016/0003-9969(83)90059-6

    authors: Horowitz M,Mittelman G,Oron Y

    更新日期:1983-01-01 00:00:00

  • Lysophosphatidic acid induces expression of genes in human oral keratinocytes involved in wound healing.

    abstract:OBJECTIVE:Epithelial cells participate in wound healing by covering wounds, but also as important mediators of wound healing processes. Topical application of the phospholipid growth factor lysophosphatidic acid (LPA) accelerates dermal wound healing and we hypothesized that LPA can play a role in human oral wound heal...

    journal_title:Archives of oral biology

    pub_type: 杂志文章

    doi:10.1016/j.archoralbio.2017.04.008

    authors: Thorlakson HH,Engen SA,Schreurs O,Schenck K,Blix IJS

    更新日期:2017-08-01 00:00:00

  • In-vitro urea-dependent pH-changes by human salivary bacteria and dispersed, artificial-mouth, bacterial plaques.

    abstract::The pH effects of urea metabolism were studied in washed salivary-sediment bacteria from subjects that had up to 10-fold variation in oral ureolytic activity, and in dispersed artificial-mouth plaques. Adequate evaluation required analysis of the [OH-] as well as the pH curve. An initial constant rate of pH-change, la...

    journal_title:Archives of oral biology

    pub_type: 杂志文章

    doi:10.1016/0003-9969(87)90132-4

    authors: Sissons CH,Cutress TW

    更新日期:1987-01-01 00:00:00

  • Synergistic effects of dexamethasone on platelet-derived growth factor mitogenesis in vitro.

    abstract::Platelet-derived growth factor (PDGF) and insulin-like growth factor-I (IGF-I) interact to stimulate proliferation of fibroblasts in culture. Glucocorticoids variably effect the response of cultured fibroblasts to polypeptide growth factors. This study determined the effects of dexamethasone on growth-factor stimulati...

    journal_title:Archives of oral biology

    pub_type: 杂志文章

    doi:10.1016/0003-9969(92)90009-w

    authors: Rutherford RB,TrailSmith MD,Ryan ME,Charette MF

    更新日期:1992-02-01 00:00:00

  • Inhibition of palatal fusion in vitro by indomethacin in two strains of mice with different H-2 backgrounds.

    abstract::Susceptibility to glucocorticoid-induced cleft palate in mice has been related to the H-2 histocompatibility complex on chromosome 17. Indomethacin administered in vitro to palatal processes from 13.5-day-old mouse embryos inhibited palatal fusion. Strains with the A background and the H-2a haplotype had significantly...

    journal_title:Archives of oral biology

    pub_type: 杂志文章

    doi:10.1016/0003-9969(89)90051-4

    authors: Montenegro MA,Palomino H

    更新日期:1989-01-01 00:00:00

  • Effects of cholinergic stimulation and aldosterone administration on salivary parotid secretion in the brushtail possum, Trichosurus vulpecula.

    abstract::Parotid salivation was stimulated by infusion of bethanechol chloride into anaesthetized brushtail possums to ascertain maximal flow rates, salivary composition and dietary adaptations of salivary function. Secretion rates for one gland ranged from 5.3 +/- 0.16 to 84.3 +/- 3.20 microliters/min (2.4 +/- 0.07 to 37.8 +/...

    journal_title:Archives of oral biology

    pub_type: 杂志文章

    doi:10.1016/0003-9969(94)90127-9

    authors: Scott NA,Beal AM

    更新日期:1994-04-01 00:00:00

  • Interleukin-2 production and bone-resorption activity in vitro by unstimulated lymphocytes extracted from chronically-inflamed human periodontal tissues.

    abstract::Lymphocytes isolated from chronically-inflamed tissues were assessed for their ability to produce lymphokines without further stimulation in vitro. Cells were extracted from tissue obtained from 42 patients undergoing periodontal surgery. Cultures were set up in triplicate and supernatants collected after 48 h were as...

    journal_title:Archives of oral biology

    pub_type: 杂志文章

    doi:10.1016/0003-9969(85)90094-9

    authors: Seymour GJ,Cole KL,Powell RN,Lewins E,Cripps AW,Clancy RL

    更新日期:1985-01-01 00:00:00

  • Extracellular potassium concentrations in human dental plaque fluid recovered from single sites.

    abstract::Previous studies using potassium ion-selective microelectrodes have demonstrated that potassium concentrations in dental plaque fluid obtained by centrifugation are identical to whole plaque values determined immediately after collection. Such procedures were now used to examine the variations in potassium concentrati...

    journal_title:Archives of oral biology

    pub_type: 杂志文章

    doi:10.1016/0003-9969(88)90030-1

    authors: Carey CM,Chow LC,Tatevossian A,Vogel GL

    更新日期:1988-01-01 00:00:00

  • Evaluation of molar and incisor bite force in indigenous compared with white population in Brazil.

    abstract::The purpose of this study was to determine maximum bite force in molar and incisor regions in young Brazilian indigenous individuals, who have had a natural diet since birth, and compare the sample with white Brazilian individuals. To do this, individuals were paired one-to-one (same weight, height, and Class I facial...

    journal_title:Archives of oral biology

    pub_type: 杂志文章

    doi:10.1016/j.archoralbio.2007.10.003

    authors: Regalo SC,Santos CM,Vitti M,Regalo CA,de Vasconcelos PB,Mestriner W Jr,Semprini M,Dias FJ,Hallak JE,Siéssere S

    更新日期:2008-03-01 00:00:00

  • Predictive factor for photodynamic therapy effects on oral squamous cell carcinoma and oral epithelial dysplasia.

    abstract:OBJECTIVE:The aim of this study was to investigate the correlation between the immunohistochemical expression of proliferating cell nuclear antigen (PCNA), factor VIII, and CD34 (markers of endothelial cells), and vascular endothelial growth factor (VEGF) and the recurrence of oral squamous cell carcinoma (OSCC) and or...

    journal_title:Archives of oral biology

    pub_type: 杂志文章

    doi:10.1016/j.archoralbio.2011.04.012

    authors: Uehara M,Ikeda H,Nonaka M,Sumita Y,Nanashima A,Nonaka T,Asahina I

    更新日期:2011-11-01 00:00:00

  • Activation of the alternate complement pathway by peptidoglycan of Actinomyces viscosus, a potentially pathogenic oral bacterium.

    abstract::Peptidoglycans and cells walls from Actinomyces viscosus, Staphylococcus aureus, and group A streptococcus were compared for their relative abilities to activate the alternate complement pathway (ACP). On the dry-weight basis, the peptidoglycan from A. viscosus was 3.5 times more active than group A streptococcal pept...

    journal_title:Archives of oral biology

    pub_type: 杂志文章

    doi:10.1016/0003-9969(83)90066-3

    authors: Baker JJ,Billy SA

    更新日期:1983-01-01 00:00:00

  • Platelet aggregation induced by uncommon serotypes of Streptococcus sanguis isolated from patients with Behçet's disease.

    abstract::Uncommon serotypes were tested for their ability to induce aggregation in platelet-rich plasma. Both uncommon and common serotypes induced platelet aggregation in rabbit platelet-rich plasma, but serotonin release was higher with the uncommon serotypes. Aggregation at ATP release varied between uncommon and common ser...

    journal_title:Archives of oral biology

    pub_type: 杂志文章

    doi:10.1016/0003-9969(91)90132-e

    authors: Isogai E,Isogai H,Yokota K,Hayashi S,Fujii N,Oguma K,Yoshikawa K,Sasamoto Y,Kotake S,Ohno S

    更新日期:1991-01-01 00:00:00

  • Effects of Candida albicans infection on defense effector secretion by human oral mucosal epithelial cells.

    abstract:OBJECTIVE:The aim of this study was to investigate the effects of Candida albicans on the production of defense effector molecules by human oral mucosal epithelial cells in vitro. DESIGN:Immortalized human oral mucosal epithelial (Leuk-1) cells and C. albicans strain 5314 were cocultured at different cell-to-C. albica...

    journal_title:Archives of oral biology

    pub_type: 杂志文章

    doi:10.1016/j.archoralbio.2019.05.013

    authors: Huang F,Song Y,Chen W,Liu Q,Wang Q,Liu W,Wang X,Wang W

    更新日期:2019-07-01 00:00:00

  • Salivary aldehyde dehydrogenase--reversible oxidation of the enzyme and its inhibition by caffeine, investigated using fluorimetric method.

    abstract:OBJECTIVE:We have applied fluorimetric method to monitor aldehyde dehydrogenase (ALDH*) activity in human saliva samples to study inactivation, reactivation and inhibition of the enzyme. DESIGN:Saliva samples were collected to buffer stock solution, containing various thiols, and assayed in the presence of the fluorog...

    journal_title:Archives of oral biology

    pub_type: 杂志文章

    doi:10.1016/j.archoralbio.2007.11.004

    authors: Wierzchowski J,Pietrzak M,Szelag M,Wroczyński P

    更新日期:2008-05-01 00:00:00

  • Impact of wear and diet on molar row geometry and topography in the house mouse.

    abstract:OBJECTIVES:Dental evolution affects the geometry of the tooth, but the adaptive relevance of these changes is related to tooth sharpness, complexity, and relief (topography). On a set of laboratory mice, we assessed how wear related to age and food consistency affected molar geometry and topography. DESIGN:Three group...

    journal_title:Archives of oral biology

    pub_type: 杂志文章

    doi:10.1016/j.archoralbio.2017.04.028

    authors: Renaud S,Ledevin R

    更新日期:2017-09-01 00:00:00

  • Structural variations in the surface zone of human tooth enamel observed by scanning electron microscopy.

    abstract::The surface zone of human deciduous and permanent enamel was examined following sectioning, polishing and etching. Three main types of surface were where prisms reached the surface, where the prisms were not discernible and those formed by a complex of both types. The aprismatic layers were measured and the percentage...

    journal_title:Archives of oral biology

    pub_type: 杂志文章

    doi:10.1016/0003-9969(82)90147-9

    authors: Whittaker DK

    更新日期:1982-01-01 00:00:00

  • The reinnervation of the tongue and salivary glands after two methods of lingual nerve repair in the cat.

    abstract::The recovery of fibres in the chorda tympani after repair by epineurial suture or entubulation was investigated. The combined trunk of the chorda tympani and lingual branch of the trigeminal nerve was sectioned unilaterally, repaired using either epineurial sutures or entubulation, and allowed to recover for 12 weeks....

    journal_title:Archives of oral biology

    pub_type: 杂志文章

    doi:10.1016/0003-9969(94)00189-i

    authors: Smith KG,Robinson PP

    更新日期:1995-05-01 00:00:00