Oscillatory mechanisms of feedforward and feedback visual processing.


:Two recent monkey studies demonstrate that feedforward processing in the visual system is reflected by activity in the 40-90Hz gamma band, whereas feedback is reflected by activity in the 5-18Hz alpha and beta band. These findings can be applied to interpret human electrophysiological activity in complex visual tasks.


Trends Neurosci


Trends in neurosciences


Jensen O,Bonnefond M,Marshall TR,Tiesinga P




Has Abstract


2015-04-01 00:00:00














  • A neuroendocrine mechanism for sustaining fear.

    abstract::Fear is an adaptive response to recognition of a potentially dangerous event. Glucocorticoids are essential for maintaining a wide variety of behavioral events by their regulation of numerous genes; one such gene encodes corticotrophin-releasing hormone (CRH). CRH is involved in diverse behavioral responses to changin...

    journal_title:Trends in neurosciences

    pub_type: 杂志文章,评审


    authors: Schulkin J,Morgan MA,Rosen JB

    更新日期:2005-12-01 00:00:00

  • Aberrant Network Activity in Schizophrenia.

    abstract::Brain dynamic changes associated with schizophrenia are largely equivocal, with interpretation complicated by many factors, such as the presence of therapeutic agents and the complex nature of the syndrome itself. Evidence for a brain-wide change in individual network oscillations, shared by all patients, is largely e...

    journal_title:Trends in neurosciences

    pub_type: 杂志文章,评审


    authors: Hunt MJ,Kopell NJ,Traub RD,Whittington MA

    更新日期:2017-06-01 00:00:00

  • The complex identity of brain tumors: emerging concerns regarding origin, diversity and plasticity.

    abstract::Elucidation of genetic and epigenetic mechanisms underlying neoplasia is one of the great success stories of modern science, but this success has not been associated with parallel improvements in the treatment of malignant tumors. One possible explanation for this failure is that the most important variables that supp...

    journal_title:Trends in neurosciences

    pub_type: 杂志文章,评审


    authors: Noble M,Dietrich J

    更新日期:2004-03-01 00:00:00

  • How does morphology relate to function in sensory arbors?

    abstract::Sensory dendrites fall into many different morphological and functional classes. Polymodal nociceptors are one subclass of sensory neurons, which are of particular note owing to their elaborate dendritic arbors. Complex developmental programs are required to form these arbors and there is striking conservation of morp...

    journal_title:Trends in neurosciences

    pub_type: 杂志文章


    authors: Hall DH,Treinin M

    更新日期:2011-09-01 00:00:00

  • Hematolymphopoietic and inflammatory cytokines in neural development.

    abstract::It is now clear that cytokines traditionally viewed as immune modulators participate in inflammatory responses within the adult nervous system. However, in the developing nervous system hematolymphopoietic cytokines also play a role unrelated to neural-immune interactions. Instead, many of these factors subserve prima...

    journal_title:Trends in neurosciences

    pub_type: 杂志文章,评审


    authors: Mehler MF,Kessler JA

    更新日期:1997-08-01 00:00:00

  • Magnetic brain stimulation: a tool to explore the action of the motor cortex on single human spinal motoneurones.

    abstract::The human brain can be stimulated by a single intense magnetic pulse over the scalp. Currents induced within the cranium excite the motor cortex and cause limb muscles to contract. The discharge of single motor units, the firing of which is maintained by voluntary effort, can be modulated by magnetic stimuli. Peri-sti...

    journal_title:Trends in neurosciences

    pub_type: 杂志文章,评审


    authors: Mills KR

    更新日期:1991-09-01 00:00:00

  • Ion Channel Functions in Early Brain Development.

    abstract::During prenatal brain development, ion channels are ubiquitous across several cell types, including progenitor cells and migrating neurons but their function has not been clear. In the past, ion channel dysfunction has been primarily studied in the context of postnatal, differentiated neurons that fire action potentia...

    journal_title:Trends in neurosciences

    pub_type: 杂志文章,评审


    authors: Smith RS,Walsh CA

    更新日期:2020-02-01 00:00:00

  • Rewiring the brain with cell transplantation in Parkinson's disease.

    abstract::Cell replacement therapy has been proposed as a means to replace lost dopaminergic neurons in Parkinson's disease (PD). In most studies, the transplanted cells have been placed within the target site, the striatum, and not within the lesioned site, the substantia nigra, as the adult nigrostriatal pathway was thought t...

    journal_title:Trends in neurosciences

    pub_type: 杂志文章,评审


    authors: Gaillard A,Jaber M

    更新日期:2011-03-01 00:00:00

  • Unveiling synaptic plasticity: a new graphical and analytical approach.

    abstract::Short-term synaptic plasticity has a key role in information processing in the CNS, whereas memories can be formed through long-lasting changes in synaptic strength. Despite the importance of these phenomena, it remains difficult to determine whether a synaptic modulation is expressed at a presynaptic or postsynaptic ...

    journal_title:Trends in neurosciences

    pub_type: 杂志文章


    authors: Clements JD,Silver RA

    更新日期:2000-03-01 00:00:00

  • Kalirin and Trio: RhoGEFs in Synaptic Transmission, Plasticity, and Complex Brain Disorders.

    abstract::Changes in the actin cytoskeleton are a primary mechanism mediating the morphological and functional plasticity that underlies learning and memory. The synaptic Ras homologous (Rho) guanine nucleotide exchange factors (GEFs) Kalirin and Trio have emerged as central regulators of actin dynamics at the synapse. The incr...

    journal_title:Trends in neurosciences

    pub_type: 杂志文章,评审


    authors: Paskus JD,Herring BE,Roche KW

    更新日期:2020-07-01 00:00:00

  • Molecular mechanisms of CNS synaptogenesis.

    abstract::Synapses of the mammalian CNS are asymmetric sites of cell-cell adhesion between nerve cells. They are designed to mediate the rapid and efficient transmission of signals from the presynaptic bouton of one neuron to the postsynaptic plasma membrane of a second neuron. Significant progress has been made in the characte...

    journal_title:Trends in neurosciences

    pub_type: 杂志文章,评审


    authors: Garner CC,Zhai RG,Gundelfinger ED,Ziv NE

    更新日期:2002-05-01 00:00:00

  • The neural network of the basal ganglia as revealed by the study of synaptic connections of identified neurones.

    abstract::The study of synaptic connections in the electron microscope has established an 'elementary' circuit for the neostriatum which consists of a pathway from cortical areas (neocortex, hippocampus, amygdala) to medium spiny neurones of the striatum that also receive converging synaptic input from midbrain dopamine neurone...

    journal_title:Trends in neurosciences

    pub_type: 杂志文章,评审


    authors: Smith AD,Bolam JP

    更新日期:1990-07-01 00:00:00

  • The Eloquent Silent Synapse.

    abstract::The ability of central synapses to undergo long-term potentiation (LTP) still captures the imagination of scientists and has become one of the most fascinating and deeply studied questions in modern neuroscience. By the mid-1990s, however, the field was deeply ensnarled in trying to answer a passionately dichotomous q...

    journal_title:Trends in neurosciences

    pub_type: 杂志文章,评审


    authors: Vincent-Lamarre P,Lynn M,Béïque JC

    更新日期:2018-09-01 00:00:00

  • Lyme disease.

    abstract::Lyme disease is of interest to the neurologist and neuroscientist for a variety of reasons. As more arthropod hosts throughout the world are infected with the causative organism, Borrelia burgdorferi, the illness in humans is becoming more prevalent; in addition, recognition of the disease in humans and susceptible an...

    journal_title:Trends in neurosciences

    pub_type: 杂志文章,评审


    authors: Pachner AR

    更新日期:1989-05-01 00:00:00

  • Friends and foes in synaptic transmission: the role of tomosyn in vesicle priming.

    abstract::Priming is the process by which vesicles become available for fusion at nerve terminals and is modulated by numerous proteins and second messengers. One of the prominent members of this diverse family is tomosyn. Tomosyn has been identified as a syntaxin-binding protein; it inhibits vesicle priming, but its mode of ac...

    journal_title:Trends in neurosciences

    pub_type: 杂志文章,评审


    authors: Ashery U,Bielopolski N,Barak B,Yizhar O

    更新日期:2009-05-01 00:00:00

  • Auditory thalamocortical transformation: structure and function.

    abstract::Communicative, predatory, and reproductive behaviors rely on the auditory thalamocortical system, a key nexus that combines, transforms, and distributes virtually all acoustic information relevant to survival. The rules of connectivity for this complex network, both anatomically and functionally, are only beginning to...

    journal_title:Trends in neurosciences

    pub_type: 杂志文章,评审


    authors: Winer JA,Miller LM,Lee CC,Schreiner CE

    更新日期:2005-05-01 00:00:00

  • The dopamine hypothesis of reward: past and current status.

    abstract::Mesolimbic dopaminergic neurons are thought to serve as a final common neural pathway for mediating reinforcement processes. However, several recent findings have challenged the view that mesolimbic dopamine has a crucial role in the maintenance of reinforcement processes, or the subjective rewarding actions of natura...

    journal_title:Trends in neurosciences

    pub_type: 杂志文章,评审


    authors: Spanagel R,Weiss F

    更新日期:1999-11-01 00:00:00

  • Language within our grasp.

    abstract::In monkeys, the rostral part of ventral premotor cortex (area F5) contains neurons that discharge, both when the monkey grasps or manipulates objects and when it observes the experimenter making similar actions. These neurons (mirror neurons) appear to represent a system that matches observed events to similar, intern...

    journal_title:Trends in neurosciences

    pub_type: 杂志文章,评审


    authors: Rizzolatti G,Arbib MA

    更新日期:1998-05-01 00:00:00

  • Neuroprotective versus Neuroinflammatory Roles of Complement: From Development to Disease.

    abstract::Complement proteins are ancient components of innate immunity that have emerged as crucial regulators of neural networks. We discuss these roles in the context of the CNS development, acute CNS viral infections, and post-infectious and noninfectious CNS disorders, with an emphasis on microglia-mediated loss of synapse...

    journal_title:Trends in neurosciences

    pub_type: 杂志文章,评审


    authors: Kanmogne M,Klein RS

    更新日期:2021-02-01 00:00:00

  • Bradykinin and inflammatory pain.

    abstract::There is compelling evidence linking bradykinin (BK) with the pathophysiological processes that accompany tissue damage and inflammation, especially the production of pain and hyperalgesia. Several mechanisms have been proposed to account for hyperalgesia including the direct activation of nociceptors as well as sensi...

    journal_title:Trends in neurosciences

    pub_type: 杂志文章,评审


    authors: Dray A,Perkins M

    更新日期:1993-03-01 00:00:00

  • The behaving brain of a fly.

    abstract::The use of Drosophila as a suitable system to answer behavioural questions is usually based on the availability of mutant phenotypes. Indeed, the 'single-gene' approach to behaviour was a very illuminating strategy in practical and conceptual terms, and served to prove that the genetic mechanisms sustaining behaviour ...

    journal_title:Trends in neurosciences

    pub_type: 杂志文章


    authors: Ferrús A,Canal I

    更新日期:1994-11-01 00:00:00

  • Tools for investigating functional interactions between ligands and G-protein-coupled receptors.

    abstract::A general assay for evaluating functional interactions between ligands and G-protein-coupled receptors within minutes has been developed. The system uses the principles employed by animals such as reptiles, amphibians and fish to control their colors. In nature, activation of G-protein-coupled receptors expressed by s...

    journal_title:Trends in neurosciences

    pub_type: 杂志文章,评审


    authors: Lerner MR

    更新日期:1994-04-01 00:00:00

  • Neural Cell Adhesion Molecules of the Immunoglobulin Superfamily Regulate Synapse Formation, Maintenance, and Function.

    abstract::Immunoglobulin superfamily adhesion molecules are among the most abundant proteins in vertebrate and invertebrate nervous systems. Prominent family members are the neural cell adhesion molecules NCAM and L1, which were the first to be shown to be essential not only in development but also in synaptic function and as k...

    journal_title:Trends in neurosciences

    pub_type: 杂志文章,评审


    authors: Sytnyk V,Leshchyns'ka I,Schachner M

    更新日期:2017-05-01 00:00:00

  • Mitochondria and Calcium in Alzheimer's Disease: From Cell Signaling to Neuronal Cell Death.

    abstract::Mitochondrial dysfunction has been implicated in the pathogenesis of almost all neurological diseases, including Alzheimer's disease (AD). Historically, a primary focus in this context has been the link between mitochondrial dynamics and amyloid β toxicity. Recent evidence suggests that dysregulation of mitochondrial ...

    journal_title:Trends in neurosciences

    pub_type: 杂志文章,评审


    authors: Calvo-Rodriguez M,Bacskai BJ

    更新日期:2021-02-01 00:00:00

  • Molecular mechanisms underlying maturation and maintenance of the vertebrate neuromuscular junction.

    abstract::The vertebrate neuromuscular junction (NMJ), a peripheral synapse formed between motoneuron and skeletal muscle, is characterized by a protracted postnatal period of maturation and life-long maintenance. In neuromuscular disorders such as congenital myasthenic syndromes (CMSs), disruptions of NMJ maturation and/or mai...

    journal_title:Trends in neurosciences

    pub_type: 杂志文章,评审


    authors: Shi L,Fu AK,Ip NY

    更新日期:2012-07-01 00:00:00

  • Axonal flip-flops and oscillators.

    abstract::The strange and unpleasant sensations (paraesthesiae) or asynchronous motor-unit activation (fasciculation) that result from a period of limb ischaemia are examples of ectopic discharge in peripheral nerves. Ectopic activity also results from demyelination and is associated with serious neurological conditions, such a...

    journal_title:Trends in neurosciences

    pub_type: 杂志文章,评审


    authors: Baker MD

    更新日期:2000-11-01 00:00:00

  • Fear conditioning and extinction: emotional states encoded by distinct signaling pathways.

    abstract::Conditioning and extinction of fear have traditionally been viewed as two independent learning processes for encoding representations of contexts or cues (conditioned stimuli, CS), aversive events (unconditioned stimuli, US), and their relationship. Based on the analysis of protein kinase signaling patterns in neurons...

    journal_title:Trends in neurosciences

    pub_type: 杂志文章,评审


    authors: Tronson NC,Corcoran KA,Jovasevic V,Radulovic J

    更新日期:2012-03-01 00:00:00

  • Regulation of neuronal function by calcium.

    abstract::In the classical picture of brain function, electrical impulses are initiated in sensory organs and spread rapidly down axons, jumping synaptic clefts by neurochemical transmission. Patterns of electrical activity generated in this way integrate information throughout the brain and result in coordinated motor output. ...

    journal_title:Trends in neurosciences

    pub_type: 杂志文章,评审


    authors: Kennedy MB

    更新日期:1989-11-01 00:00:00

  • Light Therapy in Parkinson's Disease: Towards Mechanism-Based Protocols.

    abstract::A growing body of work is investigating the safety and efficacy of light in Parkinson's disease (PD). Here we discuss the potential of this emerging therapy to improve both motor and non-motor symptoms of PD. We also highlight directions for future basic, translational, and clinical research that are critical for the ...

    journal_title:Trends in neurosciences

    pub_type: 杂志文章,评审


    authors: Fifel K,Videnovic A

    更新日期:2018-05-01 00:00:00

  • A vitamin for the brain.

    abstract::In the central nervous system (CNS) the function of retinoic acid, the active metabolite of vitamin A, is best understood from its action in guiding embryonic development; as development comes to completion, retinoic acid signaling declines. However, it is increasingly recognized that this signaling mechanism does not...

    journal_title:Trends in neurosciences

    pub_type: 杂志文章,评审


    authors: Shearer KD,Stoney PN,Morgan PJ,McCaffery PJ

    更新日期:2012-12-01 00:00:00