Abstract：
Background:Parvovirus B19 (B19) has tropism for cells of the erythroid lineage, which may lead to transient inhibition of erythropoiesis. Several studies and case reports suggested that B19 infection may contribute significantly to severe chronic anemia in HIV infected persons. Objective:To detect parvovirus B19 DNA in treatment-naïve HIV patients. Methods:This was a case control retrospective study. One hundred nineteen anemic and 81 non-anemic treatment-naïve HIV infected patients participated in the study at the Lagos University Teaching Hospital, Lagos, Nigeria. Polymerase chain reaction was used to detect B19 DNA. Results:Out of 200 patients analysed, 13(6.5%) had parvovirus B19 DNA. Eight HIV patients with anemia had B19 DNA while five non-anemic HIV patients had B19 DNA. This suggests that the presence of B19 DNA in the blood of HIV positive individuals may contribute to anemia because the majority (61.5%) who were positive for B19 DNA had anemia as compared to the non-anemic control group (38.5%). Conclusion:This study shows that the presence of B19 DNA in anemic HIV infected patients is not associated with chronic anaemia in HIV infection because no significant association exist.
journal_name
Afr Health Scijournal_title
African health sciencesauthors
Ashaka OS,Salu OB,James AB,Oyefolu AOB,Anjorin AA,Oke BO,Orenolu MR,Omilabu SAdoi
10.4314/ahs.v20i1.27subject
Has Abstractpub_date
2020-03-01 00:00:00pages
219-226issue
1eissn
1680-6905issn
1729-0503pii
jAFHS.v20.i1.pg219journal_volume
20pub_type
杂志文章abstract：BACKGROUND:The concept of pharmaceutical care is neither well developed nor adequately documented in Uganda. OBJECTIVES:This study is therefore an attempt to identify and quantify the various service components of community pharmacy practice in Kampala, Uganda's capital city. SETTING:Two pharmacies operating retail o...
journal_title：African health sciences
pub_type： 杂志文章,多中心研究
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