Magnesium Lowers the Incidence of Postoperative Junctional Ectopic Tachycardia in Congenital Heart Surgical Patients: Is There a Relationship to Surgical Procedure Complexity?


:Magnesium sulfate was given to pediatric cardiac surgical patients during cardiopulmonary bypass period in an attempt to reduce the occurrence of postoperative junctional ectopic tachycardia (PO JET). We reviewed our data to evaluate the effect of magnesium on the occurrence of JET and assess a possible relationship between PO JET and procedure complexity. A total of 1088 congenital heart surgeries (CHS), performed from 2005 to 2010, were reviewed. A total of 750 cases did not receive magnesium, and 338 cases received magnesium (25 mg/kg). All procedures were classified according to Aristotle score from 1 to 4. Overall, there was a statistically significant decrease in PO JET occurrence between the two groups regardless of the Aristotle score, 15.3 % (115/750) in non-magnesium group versus 7.1 % (24/338) in magnesium group, P < 0.001. In the absence of magnesium, the risk of JET increased with increasing Aristotle score, P = 0.01. Following magnesium administration and controlling for body weight, surgical and aortic cross-clamp times in the analyses, reduction in adjusted risk of JET was significantly greater with increasing Aristotle level of complexity (JET in non-magnesium vs. magnesium group, Aristotle level 1: 9.8 vs. 14.3 %, level 4: 11.5 vs. 3.2 %; odds ratio 0.54, 95 % CI 0.31-0.94, P = 0.028). Our data confirmed that intra-operative usage of magnesium reduced the occurrence of PO JET in a larger number and more diverse group of CHS patients than has previously been reported. Further, our data suggest that magnesium's effect on PO JET occurrence seemed more effective in CHS with higher levels of Aristotle complexity.


Pediatr Cardiol


Pediatric cardiology


He D,Sznycer-Taub N,Cheng Y,McCarter R,Jonas RA,Hanumanthaiah S,Moak JP




Has Abstract


2015-08-01 00:00:00












  • Recurrent congenital left atrial aneurysm in a newborn.

    abstract::Recurrent congenital left atrial aneurysm presenting in a newborn as cardiac tamponade is described. Such a presentation has not been previously reported. ...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Mansour E,Aldousany A,Arce O,Subramanian S,Ashraf MH

    更新日期:1998-03-01 00:00:00

  • Through Tricuspid Closure for Doubly Committed Subarterial Ventricular Septal Defect with Right Vertical Subaxillary Mini-incision: A Matched-Pair Analysis.

    abstract::To evaluate the feasibility and efficacy of the right subaxillary vertical mini-incision (RAVI) used for the closure of doubly committed subarterial ventricular septal defect (SAVSD) through tricuspid approach only. From June 2015 to September 2016, 32 SAVSD patients (mean age 2.4 ± 1.9 years, range 0.7-8 years) under...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Liu R,Rui L,Zhang B,Lin Y,Li S,Hua Z

    更新日期:2019-08-01 00:00:00

  • An old autopsy report sheds light on a "new" disease: infantile polyarteritis nodosa and kawasaki disease.

    abstract::Although Kawasaki disease (KD) was first discovered and identified in Japan by Kawasaki in the 1960s, fatal KD cases resulting from coronary artery aneurysms had been identified retrospectively in the West as early as 1871. Kawasaki initially postulated that this disease was a new, as yet unidentified, self-limiting i...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Kushner HI,Abramowsky CR

    更新日期:2010-05-01 00:00:00

  • The Deconditioning Effect of the COVID-19 Pandemic on Unaffected Healthy Children.

    abstract::The COVID-19 pandemic has had devastating direct consequences on the health of affected patients. It has also had a significant impact on the ability of unaffected children to be physically active. We evaluated the effect of deconditioning from social distancing and school shutdowns implemented during the COVID-19 pan...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Dayton JD,Ford K,Carroll SJ,Flynn PA,Kourtidou S,Holzer RJ

    更新日期:2021-01-04 00:00:00

  • Screening for Congenital Heart Disease in Infants with Down Syndrome: Is Universal Echocardiography Necessary?

    abstract::Current guidelines recommend that all neonates with Down syndrome (DS) be screened for congenital heart disease (CHD) with an echocardiogram. We sought to determine the effectiveness of a more accessible and less expensive screening strategy consisting of physical examination, electrocardiogram (ECG), and chest X-ray....

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Bogarapu S,Pinto NM,Etheridge SP,Sheng X,Liesemer KN,Young PC,Saarel EV

    更新日期:2016-10-01 00:00:00

  • Radiofrequency catheter ablation of tachycardia in patients with congenital heart disease.

    abstract::Patients with anomalies of the heart frequently suffer from arrhythmias that either are associated with a congenital heart defect or result from the course of the disease. For most of the bradyarrhythmias, appropriate timing of the initiation of treatment is more challenging than its eventual execution. In the case of...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章,评审


    authors: Hebe J,Hansen P,Ouyang F,Volkmer M,Kuck KH

    更新日期:2000-11-01 00:00:00

  • School-Age Developmental and Educational Outcomes Following Cardiac Procedures in the First Year of Life: A Population-Based Record Linkage Study.

    abstract::The purpose of the study was to evaluate school-age developmental and educational outcomes for children with and without a cardiac procedure in the first year of life to improve understanding of longer-term neurodevelopmental outcomes in children who have had a cardiac procedure for congenital heart disease, the most ...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Lawley CM,Winlaw DS,Sholler GF,Martin A,Badawi N,Walker K,Nassar N,Lain SJ

    更新日期:2019-03-01 00:00:00

  • Postoperative exercise training develops normal levels of physical activity in a group of children following cardiac surgery.

    abstract::Children with congenital heart defects often demonstrate a reduced capacity for exercise, even after surgical intervention. Forty subjects, with various heart defects, completed a 5-year study to evaluate the impact of a postoperative training program on their physical exercise capacity. All of the patients were signi...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Longmuir PE,Tremblay MS,Goode RC

    更新日期:1990-07-01 00:00:00

  • Large anomalous systemic arterial supply to the left lung without pulmonary sequestration: a rare cause of heart failure in a child.

    abstract::A 10-month-old boy was referred for tachypnea and heart murmur. An echocardiogram showed unexplained left heart dilation without evidence of an intracardiac shunt. A 64-slice computed tomographic contrast-enhanced angiography showed a large tortuous anomalous artery arising from the descending thoracic aorta and suppl...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Wong MN,Joshi P,Sim KH

    更新日期:2009-01-01 00:00:00

  • Aortic coarctation associated with alveolar capillary dysplasia and misalignment of the pulmonary veins.

    abstract::After surgical repair of an aortic coarctation a term infant presented with severe pulmonary hypertension and cyanosis unresponsive to treatment including extracorporeal membrane oxygenation. The atypical clinical course became apparent once the accompanying diagnosis of congenital alveolar capillary dysplasia with mi...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Gamillscheg A,Zobel G,Spuller E,Reiterer F,Beitzke A

    更新日期:2008-01-01 00:00:00

  • Relationship of Right Ventricular Size and Function with Respiratory Status in Duchenne Muscular Dystrophy.

    abstract::The relationship between pulmonary function and right ventricle (RV) in Duchenne muscular dystrophy (DMD) has not been evaluated. Using cardiac magnetic resonance (CMR), we describe the relationship of RV size and function with spirometry in a DMD cohort. Fifty-seven boys undergoing CMR and pulmonary function testing ...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Mehmood M,Ambach SA,Taylor MD,Jefferies JL,Raman SV,Taylor RJ,Sawani H,Mathew J,Mazur W,Hor KN,Al-Khalidi HR

    更新日期:2016-06-01 00:00:00

  • The vibratory innocent heart murmur in schoolchildren: a case-control Doppler echocardiographic study.

    abstract::In 810 schoolchildren (aged 5-14 years) the prevalence of a grade 1-3/6 vibratory innocent heart murmur (VIHM) is 41%. Restricted to a grade 2 or 3 VIHM, the prevalence is 14%, decreasing from 21% in the age-class 5-6 years to 8% for children 13-14 years of age. The prevalence of a grade 3 VIHM is 1%. Together with a ...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Van Oort A,Hopman J,De Boo T,Van Der Werf T,Rohmer J,Daniëls O

    更新日期:1994-11-01 00:00:00

  • Truncus arteriosus associated with trisomy 18.

    abstract::The spectrum of cardiac anomalies in trisomy 18 typically includes septal defects and polyvalvular disease and only rarely complex malformations. We report the first case of trisomy 18 with truncus arteriosus type II. ...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Moore JW,Wight NE,Jones MC,Krous HF

    更新日期:1994-05-01 00:00:00

  • Outcome of left atrial isomerism at a single institution.

    abstract::Left atrial isomerism includes a complex spectrum of cardiac and extracardiac anomalies. The records of all patients with left isomerism born during the period of 1973-2010 and treated at the Children's Hospital, Helsinki were reviewed. The short- and long-term outcomes were studied. The review included 38 patients (5...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Eronen MP,Aittomäki KA,Kajantie EO,Sairanen HI

    更新日期:2012-04-01 00:00:00

  • Contractility reserve in children undergoing dialysis by dobutamine stress echocardiography.

    abstract::Left ventricular hypertrophy is an adaptive mechanism in children undergoing chronic dialysis to improve contractility at rest. The aim of this study was to determine the left ventricular performance and contractility reserve by "dobutamine stress echocardiography" in children undergoing chronic dialysis. Thirty-five ...

    journal_title:Pediatric cardiology

    pub_type: 临床试验,杂志文章


    authors: Mese T,Guven B,Yilmazer MM,Serdaroglu E,Tavli V,Haydar A,Bak M

    更新日期:2010-10-01 00:00:00

  • Tetralogy of fallot with left heart hypoplasia, total anomalous pulmonary venous return, and right lung hypoplasia: role of magnetic resonance imaging.

    abstract::We report a rare case of tetralogy of Fallot with total anomalous pulmonary venous return, left heart hypoplasia, right lung hypoplasia, and left ocular-mandibular synchinesia (Marcus-Gunn phenomenon), correctly diagnosed by cardiovascular magnetic resonance imaging and successfully operated by modified Glenn anastomo...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Festa P,Lamia AA,Murzi B,Bini MR

    更新日期:2005-07-01 00:00:00

  • Characteristics and Outcomes of Heart Transplantation in DiGeorge Syndrome.

    abstract::DiGeorge syndrome (DGS) is commonly associated with both congenital heart disease (CHD) and immunologic abnormalities. While CHD may prompt consideration for heart transplantation (HTx), little is known about HTx management or outcomes in this group. The aim of this study was to describe the spectrum of patients with ...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Woolman P,Bearl DW,Soslow JH,Dodd DA,Thurm C,Hall M,Feingold B,Godown J

    更新日期:2019-04-01 00:00:00

  • N-terminal pro-brain natriuretic peptide (NT proBNP) as a predictive indicator of initial intravenous immunoglobulin treatment failure in children with Kawasaki disease: a retrospective study.

    abstract::Intravenous immunoglobulin (IVIG) administered in the acute stage of Kawasaki disease (KD) is the standard therapy. Few reports describe nonresponders to initial treatment with IVIG in KD, which remains the most consistent risk factor for coronary artery lesions (CALs). This study aimed to investigate whether the seru...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Kim SY,Han MY,Cha SH,Jeon YB

    更新日期:2013-01-01 00:00:00

  • Prenatal diagnosis of congenital heart disease and birth outcomes.

    abstract::This study was undertaken to examine the impact that prenatal diagnosis of congenital heart disease (CHD) has on birth and early neonatal outcomes. The prevalence of prenatally diagnosed CHD has risen over the past decade, but the effect that prenatal diagnosis of CHD has on peripartum decisions remains unclear. No co...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Landis BJ,Levey A,Levasseur SM,Glickstein JS,Kleinman CS,Simpson LL,Williams IA

    更新日期:2013-03-01 00:00:00

  • The Role of Computed Tomography Coronary Angiography in Kawasaki Disease: Comparison with Transthoracic Echocardiography in a 25-Case Retrospective Study.

    abstract::Although transthoracic echocardiography (TTE) is the first-line examination for the study of coronary lesions in Kawasaki disease, CT coronary angiography (CTCA) is increasingly used and showed good results. Our aim is to evaluate the contribution of CTCA in the detection of coronary lesions and to compare its results...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Jrad M,Ben Salem F,Barhoumi C,Lassoued F,Frikha W,Boukriba S,Mizouni H

    更新日期:2019-02-01 00:00:00

  • A Novel MEF2C Loss-of-Function Mutation Associated with Congenital Double Outlet Right Ventricle.

    abstract::Congenital heart defect (CHD) represents the most prevalent birth defect, and accounts for substantial morbidity and mortality in humans. Aggregating evidence demonstrates the genetic basis for CHD. However, CHD is a heterogeneous disease, and the genetic determinants underlying CHD in most patients remain unknown. In...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Lu CX,Wang W,Wang Q,Liu XY,Yang YQ

    更新日期:2018-04-01 00:00:00

  • Cardiac Rhythm Disturbances in Heterotaxy Syndrome.

    abstract:OBJECTIVE:Heterotaxy syndrome is associated with complex cardiac malformations and cardiac conduction system abnormalities. Those with right atrial isomerism (RAI) have dual sinus nodes and dual atrioventricular nodes predisposing them to supraventricular tachycardia (SVT). Those with left atrial isomerism (LAI) lack a...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Ozawa Y,Asakai H,Shiraga K,Shindo T,Hirata Y,Hirata Y,Inuzuka R

    更新日期:2019-06-01 00:00:00

  • Use of dexmedetomidine in a pediatric heart transplant patient.

    abstract::Dexmedetomidine is a new sedative and analgesic agent that has a unique property of lack of respiratory depression. We describe a pediatric case in which the use of dexmedetomidine enabled us to successfully extubate a 12-year-old heart transplant patient with acute pneumonia after several failed attempts with the use...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Chrysostomou C,Zeballos T

    更新日期:2005-09-01 00:00:00

  • The mitochondrial permeability transition pore and the cardiac necrotic program.

    abstract::That apoptosis is mediated by specific pathways has long been established. However, more recent data have begun to suggest that necrosis may in fact be "programmed" and not a default "accidental" pathway as previously thought. The mitochondrial permeability transition pore, a known contributor to the development of ma...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Baines CP

    更新日期:2011-03-01 00:00:00

  • Parent stress levels during children's hospital recovery after congenital heart surgery.

    abstract::The hospitalization of a child for cardiac surgery is known to be a stressful experience for parents. However, little is known about the time course or the relationships between parental stress and the child's actual or perceived recovery. This research aimed to investigate pre- and postoperative parental stress and t...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Franck LS,McQuillan A,Wray J,Grocott MP,Goldman A

    更新日期:2010-10-01 00:00:00

  • Doppler echocardiography with extended transesophageal atrial pacing: predicting the efficacy of permanent atrial pacing in the patient with a small left ventricle and sinus node dysfunction.

    abstract::A 2100-g neonate underwent a two-ventricular surgical repair of a right ventricle-dominant unbalanced atrioventricular septal defect associated with the heterotaxy syndrome and sinus node dysfunction. Postoperative congestive heart failure persisted despite bradycardia management by temporary ventricular pacing. Spect...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Liske MR,Duffy CE,Gidding SS,Rocchini AP

    更新日期:1999-05-01 00:00:00

  • Dual-catheter balloon occlusion aortography in pulmonary atresia with ventricular septal defect and major aorto-pulmonary collaterals.

    abstract::Angiography remains the gold standard in the preoperative evaluation of complex pulmonary blood supply in patients with pulmonary atresia, ventricular septal defect, and major aortopulmonary collateral arteries. In neonates, balloon occlusion aortography using a Berman balloon catheter is a very effective technique. H...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Lim JS,Desai T,Stumper O

    更新日期:2004-09-01 00:00:00

  • Percutaneous closure of ventricular septal defect associated with tunnel-shaped aneurysm using the Amplatzer duct occluder.

    abstract::Different devices have been used for percutaneous closure of ventricular septal defects (VSDs). Over the past 6 months, we have used the Amplatzer duct occluder for VSDs associated with tunnel-shaped aneurysm in three patients here at our institution. Due to the anatomic resemblance between such VSDs and the duct occl...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Dilawar M,Numan M,El-Sisi A,Gendi SM,Ahmad Z

    更新日期:2008-03-01 00:00:00

  • Health-related quality of life in children attending a cardiology clinic.

    abstract::Our purpose was to evaluate the impact of suspicion or confirmation of heart disease on the physical and psychosocial health of children. We utilized the Child Health Questionnaire (CHQ PF-50). Children ages 5 to 18 years attending a general cardiology clinic were eligible. Those with primary noncardiac diagnoses unre...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Walker RE,Gauvreau K,Jenkins KJ

    更新日期:2004-01-01 00:00:00

  • Cardiac surgery for Kartagener syndrome.

    abstract::Two patients (one girl, one boy) with Kartagener syndrome (situs inversus, bronchiectasis, sinusitis), despite pulmonary problems and associated congenital cardiac anomalies, were operated on at the ages of 4 years and 7 years, respectively. They had had previous palliative treatment at the age of 3 months and 1.3 yea...

    journal_title:Pediatric cardiology

    pub_type: 杂志文章


    authors: Tkebuchava T,von Segesser LK,Niederhäuser U,Bauersfeld U,Turina M

    更新日期:1997-01-01 00:00:00