Abstract：
:Magnesium sulfate was given to pediatric cardiac surgical patients during cardiopulmonary bypass period in an attempt to reduce the occurrence of postoperative junctional ectopic tachycardia (PO JET). We reviewed our data to evaluate the effect of magnesium on the occurrence of JET and assess a possible relationship between PO JET and procedure complexity. A total of 1088 congenital heart surgeries (CHS), performed from 2005 to 2010, were reviewed. A total of 750 cases did not receive magnesium, and 338 cases received magnesium (25 mg/kg). All procedures were classified according to Aristotle score from 1 to 4. Overall, there was a statistically significant decrease in PO JET occurrence between the two groups regardless of the Aristotle score, 15.3 % (115/750) in non-magnesium group versus 7.1 % (24/338) in magnesium group, P < 0.001. In the absence of magnesium, the risk of JET increased with increasing Aristotle score, P = 0.01. Following magnesium administration and controlling for body weight, surgical and aortic cross-clamp times in the analyses, reduction in adjusted risk of JET was significantly greater with increasing Aristotle level of complexity (JET in non-magnesium vs. magnesium group, Aristotle level 1: 9.8 vs. 14.3 %, level 4: 11.5 vs. 3.2 %; odds ratio 0.54, 95 % CI 0.31-0.94, P = 0.028). Our data confirmed that intra-operative usage of magnesium reduced the occurrence of PO JET in a larger number and more diverse group of CHS patients than has previously been reported. Further, our data suggest that magnesium's effect on PO JET occurrence seemed more effective in CHS with higher levels of Aristotle complexity.
journal_name
Pediatr Cardioljournal_title
Pediatric cardiologyauthors
He D,Sznycer-Taub N,Cheng Y,McCarter R,Jonas RA,Hanumanthaiah S,Moak JPdoi
10.1007/s00246-015-1141-5subject
Has Abstractpub_date
2015-08-01 00:00:00pages
1179-85issue
6eissn
0172-0643issn
1432-1971journal_volume
36pub_type
杂志文章abstract：:We report a 6-year-old girl with superoinferior ventricles, criss-cross atrioventricular (AV) relationships with solitus atria, a D-loop, L-transposition of the great arteries, subpulmonary stenosis, but without a ventricular septal defect (VSD). The diagnosis was made by echocardiographic examination and was strength...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF00795379
更新日期：1993-10-01 00:00:00
abstract：:Anatomic evidence of intrauterine closure of ventricular septal defects (VSDs) has been reported rarely. Between 1985 and 1990, 112 autopsies were performed at the Mayo Clinic on third trimester stillborns and infants who died during the first week of life. There were 21 (19%) cases of congenital heart disease. VSD wa...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF00797004
更新日期：1994-01-01 00:00:00
abstract：:Pediatric cardiothoracic surgery is often associated with low cardiac output in the postoperative period. This study sought to determine whether increasing heart rate via temporary atrial pacing is beneficial in augmenting cardiac output. Patients younger than 18 years who underwent cardiothoracic surgery and had no p...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-013-0687-3
更新日期：2013-10-01 00:00:00
abstract：:The epinephrine test has been shown to be a powerful tool to predict the genotype of congenital long QT syndrome (LQTS). The aim of this study was to evaluate its role in the diagnosis and management of LQTS in children. The test (using the Shimizu protocol) was conducted in patients with some evidence of LQTS but in ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-009-9603-2
更新日期：2010-05-01 00:00:00
abstract：:Use of extracorporeal membrane oxygenation (ECMO) in infants with congenital heart disease is becoming more frequent. We present the first reported use of balloon atrial septostomy during ECMO support and describe possible complications of such procedures unique to ECMO therapy. ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF00795647
更新日期：1993-07-01 00:00:00
abstract：:A large ductus arteriosus aneurysm can lead to potentially serious and life-threatening complications. We report a case of aneurysmal dilatation of the ductus arteriosus in a premature infant that was successfully treated with indomethacin. Thus, surgical intervention with general anesthesia could be avoided. ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-005-1164-4
更新日期：2006-01-01 00:00:00
abstract：:Adrenomedullin (ADM) is a vasoactive peptide with potent dilatory effects. We studied whether perioperative myocardial injury could be altered by the presence of ADM. Blood samples from 19 children with congenital heart disease undergoing surgical repair were collected at six time points: preoperative, on cardiopulmon...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s002460010046
更新日期：2000-05-01 00:00:00
abstract：:Ebstein anomaly of mitral valve (MV) is an extremely rare congenital heart disease. In the current report, we present a case of Ebstein of MV that was diagnosed prenatally. Fetal echocardiogram showed that the posterior leaflet of MV was tethered to the lateral wall of left ventricle (LV) with downward displacement in...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-018-1903-y
更新日期：2018-08-01 00:00:00
abstract：:Hyperplastic left heart syndrome (HLHS) patients are palliated by creating a Fontan-type circulation passing from different surgical stages. The aim of this work is to describe the evolution of ventricular energetics parameters in HLHS patients during the different stages of palliation including the hybrid, the Norwoo...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-017-1704-8
更新日期：2017-12-01 00:00:00
abstract：:Ionizing radiation exposure is a necessary risk entailed during congenital cardiac catheterizations. The congenital catheterization lab at Yale New Haven Children's Hospital employed quality improvement strategies to minimize radiation exposure in this vulnerable population. In two phases, we implemented six intervent...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-018-2039-9
更新日期：2019-03-01 00:00:00
abstract：:Right ventricular (RV) remodeling in hypoplastic left heart syndrome (HLHS) begins prenatally and continues through staged palliations. However, it is unclear if the most marked observed remodeling post-Norwood is secondary to cardiopulmonary bypass (CPB) exposure or if it is an adaptation intrinsic to the systemic RV...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-020-02482-0
更新日期：2020-10-10 00:00:00
abstract：:The inauguration of Sequential Segmental Analysis (SSA) a few decades ago provides basic conditions to establish a universally applicable classification system for cardiac malformations. To gain practical experience, we used this method to classify a collection of 292 congenitally malformed human hearts. Our aims were...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/pl00021002
更新日期：2002-09-01 00:00:00
abstract：:Congenital heart defects (CHD) are the third leading cause of death in children <1 year of age in Mexico where there is a high prevalence of the 677C → T polymorphism of the MTHFR gene. This is important because the homozygous 677T/T MTHFR gene and deficiency of folic acid (FA) intake have been associated with CHD. Ou...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-012-0380-y
更新日期：2013-01-01 00:00:00
abstract：:We sought to document morbidities and growth for patients with hypoplastic left heart syndrome (HLHS) to inform the initial surgical decision and understand healthcare needs. Data were obtained on 137 patients with HLHS, born between 1989 and 1994, who survived staged surgery ( n = 62) or transplantation ( n = 75) and...
journal_title：Pediatric cardiology
pub_type： 杂志文章,多中心研究
doi：10.1007/s00246-003-0471-x
更新日期：2004-01-01 00:00:00
abstract：:A fetal echocardiographic scan was performed when routine prenatal ultrasound screening failed to identify four cardiac chambers. The scan showed a single ventricle with an associated circoid varicosity. Because of these anomalies, amniocentesis was suggested and trisomy 18 confirmed. The presence of major cardiac str...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF00794843
更新日期：1993-01-01 00:00:00
abstract：:A retrospective study of children dying with active varicella revealed 11 of 17 cases who had unsuspected interstitial myocarditis at the time of their death. In addition, a prospective study of 6 children, consecutively admitted to the hospital with active varicella, were evaluated for evidence of cardiac dysfunction...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF02082333
更新日期：1982-01-01 00:00:00
abstract：:In a patient with single ventricle, mitral atresia, common atrium, pulmonary stenosis, azygos continuation of the inferior vena cava and bilateral systemic artery--pulmonary artery anastomoses, the systemic veins were connected directly to the pulmonary arteries to achieve physiologic repair; the child was discharged ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：
更新日期：1986-01-01 00:00:00
abstract：:Chylothorax is a well-described complication after cardiothoracic surgery in children. Medical nutritional therapy for chylothorax includes medium-chain triglyceride (MCT) formulas and reduction in enteral long-chain triglyceride intake to reduce chyle production. Human milk is usually eliminated from the diet of infa...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-016-1393-8
更新日期：2016-08-01 00:00:00
abstract：:Isolation of the left innominate artery arising from the ductus arteriosus is a rare clinical entity with only nine cases being reported in the literature [5, 7, 8]. We describe a case consisting of tetralogy of Fallot, right aortic arch, and isolation of the left innominate artery arising from a left-sided ductus art...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s002460010154
更新日期：2001-01-01 00:00:00
abstract：:A hemodynamically stable neonate with transposition of the great arteries suddenly went into cardiac arrest during preparation for transport to the operating room. Emergency echocardiography during cardiac massage detected coronary air embolism as the presumed cause of arrest. After about 15 minutes of resuscitation, ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-011-0088-4
更新日期：2011-12-01 00:00:00
abstract：:Cardiac involvement of Duchenne and Becker muscular dystrophies (DMD/BMD) is the most common cause of fatal outcomes. It is still unclear whether some DMD/BMD gene mutations might be predictive of cardiac involvement. In this study, we provide a comprehensive overview on genotypes of cardiac disease in DMD/BMD. We sys...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-020-02470-4
更新日期：2020-10-09 00:00:00
abstract：:A reduced exercise capacity is a common finding in adult congenital heart disease and is associated with cardiovascular morbidity and mortality. However, data on exercise capacity in patients after repair of coarctation of the aorta (CoA) are scarce. Furthermore, a high rate of exercise-induced hypertension has been d...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-019-02173-5
更新日期：2019-10-01 00:00:00
abstract：:Cardiac surgery for congenital heart disease often necessitates a period of myocardial ischemia during cardiopulmonary bypass and cardioplegic arrest, followed by reperfusion after aortic cross-clamp removal. In experimental models, myocardial ischemia-reperfusion is associated with significant oxidative stress and ve...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-016-1345-3
更新日期：2016-04-01 00:00:00
abstract：:The current pulse-oximetry screening (POS) protocol for detection of critical congenital heart defects (CCHDs) is recommended only for newborns in well-infant and intermediate care nurseries, and there is no evidence-based protocol for infants discharged from the neonatal intensive care unit (NICU). The objectives of ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-013-0793-2
更新日期：2014-03-01 00:00:00
abstract：:A 9-year-old girl was admitted because she had had palpitations for 2 years. Her electrocardiogram revealed multifocal ectopic beats with left bundle branch morphology, sinoatrial block, and first- and second-degree atrioventricular blocks. Cross-sectional echocardiography demonstrated an enlarged left ventricle and f...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF02505810
更新日期：1996-01-01 00:00:00
abstract：:The purpose of this study was to describe the long-term outcome of infants with hypoplastic left heart syndrome (HLHS) who underwent placement of internal pulmonary artery bands as part of a transcatheter palliation procedure followed by primary heart transplantation. Transcatheter palliation included stenting of the ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-009-9424-3
更新日期：2009-05-01 00:00:00
abstract：:The longer survival of patients with Duchenne muscular dystrophy due to advances in clinical care has increased the incidence of Duchenne muscular dystrophy-associated cardiomyopathy, a nearly consistent feature in the third decade of life. A 26-year-old patient with Duchenne muscular dystrophy experienced severe acut...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-019-02072-9
更新日期：2019-03-01 00:00:00
abstract：:An atrial septal aneurysm (ASA) is an increasingly recognized entity that involves septal tissue significantly bulging into either atria instead of remaining in a relatively neutral position. ASAs may be described based on the length of the segment of atrial septal tissue involved as well as the distance and direction...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-018-2017-2
更新日期：2019-01-01 00:00:00
abstract：:The case report describes a 9-year-old boy who presented with an acute cerebrovascular accident and was found to have cardiac tamponade caused by cardiac rhabdomyosarcoma. Symptoms of rhabdomyosarcoma can be indolent and nonspecific, even with metastatic disease. Echocardiography and cardiac magnetic resonance imaging...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-012-0549-4
更新日期：2013-03-01 00:00:00
abstract：:That apoptosis is mediated by specific pathways has long been established. However, more recent data have begun to suggest that necrosis may in fact be "programmed" and not a default "accidental" pathway as previously thought. The mitochondrial permeability transition pore, a known contributor to the development of ma...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-010-9880-9
更新日期：2011-03-01 00:00:00
