Abstract:
PURPOSE:Neurocognitive outcomes are frequently used as indicators of real-world functioning in schizophrenia spectrum disorders (SSD). These test results may be influenced by individual differences, such as affective dispositions. Here we investigate the relationship between positive and negative affect and neuropsychological test scores in a large, mixed-gender, population based group of participants without co-morbid substance abuse. MATERIALS AND METHODS:We assessed 129 male and female SSD patients with the Positive and Negative Affect Schedule (PANAS) and a comprehensive neuropsychological test battery. RESULTS AND CONCLUSIONS:The neuropsychological test scores were mainly predicted by age and gender, with small contributions from negative psychosis symptoms. There was a statistically significant relationship between Positive Affect and processing speed and between Negative Affect and verbal memory and executive function. However, the level of neurocognitive function variance explained by these affects was only 5%. Thus, the neurocognitive test results were not associated with trait affect in any clinically significant manner. This adds to previous findings of no relationship between affective dispositions and psychosis symptom variables in our participants. We suggest that affective traits constitute an independent dimension that may influence well-being, coping, and real-life outcome in SSD patients directly, and not through neurocognitive function.
journal_name
Nord J Psychiatryjournal_title
Nordic journal of psychiatryauthors
Mohn C,Olsson AK,Johansson M,Moradi H,Helldin Ldoi
10.1080/08039488.2020.1862294subject
Has Abstractpub_date
2021-01-06 00:00:00pages
1-7eissn
0803-9488issn
1502-4725pub_type
杂志文章abstract:BACKGROUND:Deep brain stimulation is a treatment under investigation for a range of psychiatric disorders. It has shown promising results for therapy-refractory obsessive-compulsive disorder (OCD) and major depressive disorder (MDD). Other indications under investigation include Tourette's syndrome, anorexia nervosa an...
journal_title:Nordic journal of psychiatry
pub_type: 杂志文章,评审
doi:10.3109/08039488.2016.1162846
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND:High levels of childhood traumatic experiences have been observed among substance abusers. There has been insufficient study of the effects of childhood trauma in adulthood. OBJECTIVE:The aim of this study is to research the relationship between childhood trauma, self-esteem, and levels of depression and an...
journal_title:Nordic journal of psychiatry
pub_type: 杂志文章
doi:10.3109/08039488.2014.981856
更新日期:2015-05-01 00:00:00
abstract::The neurodevelopmental hypothesis of schizophrenia has gained increasing acceptance. This hypothesis assumes a disruption in the normal development of the brain, secondary to genetic factors, environmental factors, or, most likely, a combination of both. After a brief review of the various aetiologic models since the ...
journal_title:Nordic journal of psychiatry
pub_type: 杂志文章,评审
doi:10.1080/080394801317080792
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journal_title:Nordic journal of psychiatry
pub_type: 杂志文章
doi:10.1080/08039488.2018.1493747
更新日期:2018-11-01 00:00:00
abstract:BACKGROUND:The Schedule for Affective Disorders and Schizophrenia-Present and Lifetime Version (K-SADS-PL) is a semi-structured interview based on the Diagnostic and Statistical Manual of Mental Disorders (DSM), and assesses past and present symptoms in children aged 6-18 years old. It has been translated into more tha...
journal_title:Nordic journal of psychiatry
pub_type: 杂志文章
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abstract:BACKGROUND:Although the effect of obsessive-compulsive disorder (OCD) on sleep is not well-known, recent studies suggest an association between OCD and sleep quality. AIMS:We aimed to assess sleep quality in children and adolescents with OCD and to seek its association with OCD symptoms and OCD severity. METHODS:All ...
journal_title:Nordic journal of psychiatry
pub_type: 杂志文章
doi:10.1080/08039488.2020.1785005
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abstract::Although there are a great many epidemiological studies of psychiatric diseases and the outcomes of controlled rehabilitation programmes, there is a shortage of studies of routine psychiatric care. This study is a retrospective cohort study of the total number (n=138) of patients receiving inpatient care at a psychiat...
journal_title:Nordic journal of psychiatry
pub_type: 杂志文章
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journal_title:Nordic journal of psychiatry
pub_type: 杂志文章
doi:10.3109/08039488.2015.1074282
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abstract:BACKGROUND:Previous meta-analyses of paediatric obsessive-compulsive disorder (OCD) have shown much higher effect size for standard individual cognitive behaviour therapy (SI-CBT) compared with control conditions than for serotonin reuptake inhibitors (SRIs) compared with placebo. Other factors, such as systematic diff...
journal_title:Nordic journal of psychiatry
pub_type: 杂志文章,meta分析,评审
doi:10.3109/08039488.2014.941395
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journal_title:Nordic journal of psychiatry
pub_type: 杂志文章
doi:10.3109/08039488.2015.1112832
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abstract:BACKGROUND:The exact mechanisms for antipsychotic-induced extrapyramidal side-effects have remained obscure despite intensive research. Previous studies have highlighted a central role for nigral dopamine D(2) receptors in the control of motor functions. AIMS:The aim of the present study was to examine relationships b...
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pub_type: 杂志文章
doi:10.3109/08039480903484076
更新日期:2010-08-01 00:00:00
abstract:BACKGROUND:Although cognitive behavioural therapy (CBT) has been shown to be an efficacious treatment for social phobia (SP), many patients drop out or achieve little or no benefit from treatment. This fact is generally considered an argument for the importance of studies of predictor variables. AIMS:This paper system...
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pub_type: 杂志文章,评审
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更新日期:2010-04-01 00:00:00
abstract:BACKGROUND:Patients with bipolar disorder have neurocognitive impairments, which are associated with poor functional outcomes. AIMS:This study evaluated the neurocognitive effects of aripiprazole in adolescents and young adults with bipolar disorder. METHODS:This was a 24-week, observational, prospective study perfor...
journal_title:Nordic journal of psychiatry
pub_type: 杂志文章
doi:10.3109/08039488.2011.643484
更新日期:2012-09-01 00:00:00
abstract:BACKGROUND:Schizophrenia is a highly heterogeneous disease. Event-related potentials have been regarded to establish intermediate phenotypes of schizophrenia. Our previous study found that patients with deficit schizophrenia (DS) are relatively homogeneous and show a significantly longer onset latency of contingent neg...
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pub_type: 杂志文章
doi:10.3109/08039488.2014.959562
更新日期:2015-04-01 00:00:00
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journal_title:Nordic journal of psychiatry
pub_type: 杂志文章
doi:10.1080/080394801750093625
更新日期:2001-01-01 00:00:00
abstract::Obsessive-compulsive disorder (OCD) is a frequently encountered disorder in children and adolescents. Several characteristics make the disorder a challenge to diagnostic methods and treatment procedures including the diversity of symptoms, the delay of referral and the occurrence of comorbidity. The aim of the present...
journal_title:Nordic journal of psychiatry
pub_type: 杂志文章
doi:10.1080/08039480801984065
更新日期:2008-01-01 00:00:00
abstract::Conduct disorder (CD) is a condition that describes an aggressive, antisocial and criminal individual with social maladjustment. A diagnostician must consider symptoms, time and function when making a diagnosis. The aim of the article is to provide a general outline of the CD diagnosis described in DSM, using three da...
journal_title:Nordic journal of psychiatry
pub_type: 杂志文章,评审
doi:10.1080/08039480802626939
更新日期:2009-01-01 00:00:00
abstract::In the research process, hypotheses, observations and raw data are systematically transformed into new knowledge and scientific rules. People and human input are essential features of the research; the intellectual process performed by the individual scientists and their team. Unplanned administration and human confli...
journal_title:Nordic journal of psychiatry
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doi:10.1080/080394802753617999
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abstract::Aims: This study describes changes in alcohol habits in age and gender strata among the Swedish general population during the 21-year period following the Swedish EU membership in 1995. Methods: The Alcohol Use Disorders Identification Test (AUDIT) was distributed as a postal questionnaire to randomly selected cross-s...
journal_title:Nordic journal of psychiatry
pub_type: 杂志文章
doi:10.1080/08039488.2019.1660912
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更新日期:2019-01-01 00:00:00
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pub_type: 杂志文章
doi:10.1080/08039480600601282
更新日期:2006-01-01 00:00:00
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pub_type: 杂志文章
doi:10.1080/08039488.2019.1606938
更新日期:2019-01-01 00:00:00
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journal_title:Nordic journal of psychiatry
pub_type: 杂志文章
doi:10.1080/08039488.2017.1291720
更新日期:2017-05-01 00:00:00
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journal_title:Nordic journal of psychiatry
pub_type: 杂志文章
doi:10.1080/08039488.2019.1707283
更新日期:2020-05-01 00:00:00
abstract:OBJECTIVE:Hoarding is common in obsessive-compulsive disorder (OCD), and OCD with hoarding may have poorer prognostic features than OCD without hoarding. The aim of this study was to investigate the relationship between multifaceted impulsivity and hoarding symptoms in individuals with OCD. This relationship is importa...
journal_title:Nordic journal of psychiatry
pub_type: 杂志文章
doi:10.1080/08039488.2020.1838605
更新日期:2020-11-04 00:00:00
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journal_title:Nordic journal of psychiatry
pub_type: 杂志文章
doi:10.3109/08039488.2011.565800
更新日期:2011-12-01 00:00:00
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journal_title:Nordic journal of psychiatry
pub_type: 杂志文章
doi:10.1080/08039488.2019.1658127
更新日期:2019-11-01 00:00:00
abstract:UNLABELLED:Schizophrenia, with incidence of 1% worldwide, is a common mental disorder. Phosphoinositide-3-kinases (PI3Ks) are a family of enzymes involved in cellular functions such as cell growth, proliferation, differentiation, motility, intracellular trafficking, and survival. These enzymes play an important role in...
journal_title:Nordic journal of psychiatry
pub_type: 杂志文章
doi:10.3109/08039488.2015.1092171
更新日期:2016-01-01 00:00:00