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Tumor promotion by exposure to radiofrequency electromagnetic fields below exposure limits for humans.

Abstract：

:The vast majority of in vitro and in vivo studies did not find cancerogenic effects of exposure to electromagnetic fields (RF-EMF), i.e. emitted by mobile phones and base stations. Previously published results from a pilot study with carcinogen-treated mice, however, suggested tumor-promoting effects of RF-EMF (Tillmann et al., 2010). We have performed a replication study using higher numbers of animals per group and including two additional exposure levels (0 (sham), 0.04, 0.4 and 2 W/kg SAR). We could confirm and extend the originally reported findings. Numbers of tumors of the lungs and livers in exposed animals were significantly higher than in sham-exposed controls. In addition, lymphomas were also found to be significantly elevated by exposure. A clear dose-response effect is absent. We hypothesize that these tumor-promoting effects may be caused by metabolic changes due to exposure. Since many of the tumor-promoting effects in our study were seen at low to moderate exposure levels (0.04 and 0.4 W/kg SAR), thus well below exposure limits for the users of mobile phones, further studies are warranted to investigate the underlying mechanisms. Our findings may help to understand the repeatedly reported increased incidences of brain tumors in heavy users of mobile phones.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Lerchl A,Klose M,Grote K,Wilhelm AF,Spathmann O,Fiedler T,Streckert J,Hansen V,Clemens M

doi

10.1016/j.bbrc.2015.02.151

subject

Has Abstract

pub_date

2015-04-17 00:00:00

pages

585-90

issue

4

eissn

0006-291X

issn

1090-2104

pii

S0006-291X(15)00398-8

journal_volume

459

pub_type

杂志文章

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