Gamma and pulse radiolysis investigation of the reaction of desferrioxamine with superoxide anions.

abstract：PURPOSE:One of the most important issues regarding radiofrequency electromagnetic fields (RF-EMF) is their effect on genetic material. Therefore, we investigated the cytogenotoxic effects of 900 MHz radiofrequency electromagnetic fields (RF-EMF) and the effect of a recovery period after exposure to RF-EMF on bone marro...

journal_title：International journal of radiation biology

authors： Atlı Şekeroğlu Z,Akar A,Şekeroğlu V

更新日期：2013-11-01 00:00:00

abstract：:Lethal mutations are induced in mammalian cells mainly, perhaps wholly, within the dose range encompassing the 'shoulder,' and may well be attributable to error-prone Q-repair. ...

journal_title：International journal of radiation biology

authors： Alper T,Mothersill C,Seymour CB

更新日期：1988-10-01 00:00:00

abstract：PURPOSE:Melanoma is mainly treated by surgery and rarely with radiation because of the high radioresistance of this tumor. Nevertheless, radiotherapy is the preferred treatment modality for unresectable lesions and avoiding cosmetic disfigurement caused by surgical excision. This study investigated the therapeutic adva...

journal_title：International journal of radiation biology

authors： Kim SR,Kim EH

更新日期：2017-05-01 00:00:00

abstract：PURPOSE:We already reported that levels of interferon (IFN)-γ have been shown to be markedly reduced in mice seven weeks after irradiation, resulting in a T helper (Th) 1/Th2 imbalance. To investigate whether the single or fractionated γ-irradiation induced an immune imbalance, we analysed the Th1-related immune respon...

journal_title：International journal of radiation biology

authors： Park HR,Jo SK,Eom HS

更新日期：2011-05-01 00:00:00

abstract：PURPOSE:To investigate the influence of chromatin organization and scavenging capacity in relation to irradiation temperature on the induction of double-strand breaks (DSB) in structures derived from human diploid fibroblasts. MATERIALS AND METHODS:Agarose plugs with different chromatin structures (intact cells+/-wort...

journal_title：International journal of radiation biology

authors： Elmroth K,Nygren J,Stenerlöw B,Hultborn R

更新日期：2003-10-01 00:00:00

abstract：UNLABELLED:Abstract Purpose: Sensitizing cancer cells to irradiation is a major challenge in clinical oncology. We aimed to define the signal transduction pathways involved in poly(ADP-ribose) polymerase (PARP) inhibitor-induced radiosensitization in various mammalian cancer lines. MATERIALS AND METHODS:Clonogenic sur...

journal_title：International journal of radiation biology

authors： Hocsak E,Cseh A,Szabo A,Bellyei S,Pozsgai E,Kalai T,Hideg K,Sumegi B,Boronkai A

更新日期：2014-12-01 00:00:00

abstract：:The repair activity of verbascoside (VER), isolated from Pedicularis spicata, towards the oxidizing hydroxyl radical adduct of dGMP and its reaction mechanism were studied using pulse radiolysis. Upon pulse radiolysis of nitrous oxide saturated aqueous solution of 2'-deoxyguanosine-5'-monophosphate (dGMP) and VER, it ...

journal_title：International journal of radiation biology

authors： Li W,Zheng R,Su B,Jia Z,Li H,Jiang Y,Yao S,Lin N

更新日期：1996-04-01 00:00:00

abstract：:A/J and C57BL/6J mice, strains which differ in susceptibility to chemical-induced lung tumours, were examined for differential sensitivity to radon-induced lung cancer. Sixty weeks after exposure to 952 WLM radon (3.34 J h1 m-3), no lung tumours were found in the control, sham- (one dust-) exposed, or radon-exposed C5...

journal_title：International journal of radiation biology

authors： Groch KM,Khan MA,Brooks AL,Saffer JD

更新日期：1997-03-01 00:00:00

abstract：PURPOSE:Dose response and repair kinetics of phosphorylated histone H2A isoform X (gamma-H2AX) foci in T-lymphocytes were investigated in the low-dose range after in vitro irradiation of whole blood and T-lymphocytes with 100 kVp X-rays and (60)Co gamma-rays. MATERIALS AND METHODS:Whole blood or isolated T-lymphocytes...

journal_title：International journal of radiation biology

authors： Beels L,Werbrouck J,Thierens H

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Element-specific biokinetic models are used to reconstruct doses to systemic tissues from internal emitters. Typically, a systemic model for a radionuclide explicitly depicts only its dominant repositories. Remaining tissues and fluids are aggregated into a pool called Other tissue in which the radionuclide ...

journal_title：International journal of radiation biology

authors： Leggett RW,Tolmachev SY,Boice JD Jr

更新日期：2018-12-04 00:00:00

abstract：PURPOSE:Radioresistance is highly correlated with radiotherapy failure in clinical cancer treatment. In the current study, we sought to examine the efficacy of Celecoxib and Afatinib co-treatment as radiosensitizers in the management of non-small cell lung cancer (NSCLC) A549 cells. MATERIALS AND METHODS:Generally, A5...

journal_title：International journal of radiation biology

authors： Zhang P,Song E,Jiang M,Song Y

更新日期：2020-11-12 00:00:00

abstract：:The existence of a correlation between experimental probabilities of cell inactivation by charged particles and calculated probabilities for K-vacancy production in heavy atoms (C, N, O, P) of the DNA of cell nuclei is established. Both phenomena display a similar dependence upon the linear energy transfer (LET) of in...

journal_title：International journal of radiation biology

authors： Chetioui A,Despiney I,Guiraud L,Adoui L,Sabatier L,Dutrillaux B

更新日期：1994-05-01 00:00:00

abstract：:Most estimates of the radiation dose lethal to 50 per cent of a human population are based on historical data taken from well-known experiences reflecting inadequately known physical and biological conditions, or from medical procedures where individual patients received advantages of modern clinical care. It has been...

journal_title：International journal of radiation biology

authors： Morris MD,Jones TD

更新日期：1989-03-01 00:00:00

abstract：PURPOSE:To determine the relative toxicity of alpha- and beta-radiations under conditions of controlled temporal and spatial dose distribution. METHODS:Fused aluminosilicate particles were radiolabelled with either (45)Ca (a beta-emitter) or (242)Cm (an alpha-emitter). These were injected into CBA/Ca mice to give life...

journal_title：International journal of radiation biology

authors： Priest ND,Hoel DG,Brooks PN

更新日期：2010-04-01 00:00:00

abstract：PURPOSE:To investigate within the framework of a multilaboratory study the suitability of FISH chromosome painting to measure so-called stable translocations in peripheral lymphocytes of Mayak nuclear-industrial workers (from the Southern Urals) and their use for retrospective biodosimetry. MATERIALS AND METHODS:Chrom...

journal_title：International journal of radiation biology

authors： Bauchinger M,Braselmann H,Savage JR,Natarajan AT,Terzoudi GI,Pantelias GE,Darroudi F,Figgitt M,Griffin CS,Knehr S,Okladnikova ND,Santos S,Snigiryova G

更新日期：2001-03-01 00:00:00

abstract：:Samples of human rib were collected at autopsy and 20 were selected for marrow fat cell measurement, representing an age range of 16-96 years. The mean diameter of fat cells in red bone marrow of human rib was found to increase from around 48 microns at ages 16-29 years to around 65 microns at ages 82-96 years. There ...

journal_title：International journal of radiation biology

authors： Allen JE,Henshaw DL,Keitch PA,Fews AP,Eatough JP

更新日期：1995-12-01 00:00:00

abstract：:The aim was to investigate further the relationship between radiation-induced mitotic delay and the expression of chromosome damage in V79 cells. Recently published data on the time-course of chromosome aberrations in V79 first-cycle metaphases after exposure to 10.4 MeV u(-1) Ar ions (LET = 1226 keV microm(-1)) were ...

journal_title：International journal of radiation biology

authors： Gudowska-Nowak E,Kleczkowski A,Nasonova E,Scholz M,Ritter S

更新日期：2005-01-01 00:00:00

abstract：:Reasonable expectations, based on the normal physiology of the human fetus, cast new light on the possibilities of extrapolation from the finding of severe mental retardation (SMR) in Japanese bomb survivors after maternal exposure to 1.8-5.5 Gy T65DR Gy. After such large exposures the fetal haematopoietic tissues (DS...

journal_title：International journal of radiation biology

authors： Mole RH

更新日期：1990-10-01 00:00:00

abstract：PURPOSE:To estimate gamma-ray doses received by Hiroshima atomic bomb survivors using electron spin resonance (ESR) of tooth enamel and to compare the results with cytogenetic data. MATERIALS AND METHODS:Tooth enamel ESR was performed for 100 teeth donated from 69 Hiroshima survivors, and conventional cytogenetic exam...

journal_title：International journal of radiation biology

authors： Nakamura N,Miyazawa C,Sawada S,Akiyama M,Awa AA

更新日期：1998-06-01 00:00:00

abstract：:The relative contributions of the OH-mediated and direct radiation effect on the induction of DNA double-strand breaks (dsbs) were evaluated in two haploid yeast cell lines (GSH+ and gsh-) irradiated under oxic or hypoxic conditions in the absence or presence of 6 M glycerol as an OH radical scavenger. Gsh- cells are ...

journal_title：International journal of radiation biology

authors： Frankenberg D,Frankenberg-Schwager M,Harbich R

更新日期：1993-11-01 00:00:00

abstract：:Cell cycle dependence for the induction of 6-thioguanine-resistant mutation was investigated using synchronized mouse L5178Y cells after exposure to 4 Gy to 60Co gamma-rays or 1 Gy of 252Cf radiation (fission neutrons). Maximal mutation frequency was observed immediately after release from colcemid block (G2/M phase) ...

journal_title：International journal of radiation biology

authors： Tauchi H,Nakamura N,Sawada S

更新日期：1993-04-01 00:00:00

abstract：PURPOSE:To examine the heat sensitivity of DNA-dependent protein kinase (DNA-PK) activity in a variety of cultured mouse, hamster and human cell lines. MATERIALS AND METHODS:Eight cell lines, which have been routinely used in our laboratory, were examined. Cells were heated at 44.0 +/- 0.05 degrees C and DNA-PK activi...

journal_title：International journal of radiation biology

authors： Umeda N,Matsumoto Y,Yin HL,Tomita M,Enomoto A,Morita A,Mizukoshi T,Sakai K,Hosoi Y,Suzuki N

更新日期：2003-08-01 00:00:00

abstract：:Mouse C3H 10T1/2 cells are most sensitive to radiation-induced neoplastic transformation in the G2/M-phase of the cell cycle. When synchronized 10T1/2 cells were exposed to phorbol 12-myristate 13-acetate (TPA) after irradiation, transformation of cells not in the transformation-sensitive window was enhanced, but tran...

journal_title：International journal of radiation biology

authors： Wells RL,Cao J,Xing Y,He L,Elkind MM

更新日期：1993-12-01 00:00:00

abstract：PURPOSE:To investigate the induction of chromosomal aberrations in mouse m5S cells after exposure to power-line frequency magnetic fields (extremely low frequency magnetic fields; ELFMF) at high-flux densities. MATERIAL AND METHOD:m5S cells were either untreated or pretreated during the G1 phase with mitomycin C (MMC,...

journal_title：International journal of radiation biology

authors： Yaguchi H,Yoshida M,Ding GR,Shingu K,Miyakoshi J

更新日期：2000-12-01 00:00:00

abstract：PURPOSE:Cells derived from individuals in which the ataxia telangiectasia (ATM) gene is mutated are hypersensitive to ionizing radiation. Whether differences in ATM protein levels exist among human malignant glioma cell lines and whether such differences are correlated with cellular radiosensitivity were determined. M...

journal_title：International journal of radiation biology

authors： Chan DW,Gately DP,Urban S,Galloway AM,Lees-Miller SP,Yen T,Allalunis-Turner J

更新日期：1998-08-01 00:00:00

abstract：PURPOSE:Although the significance of cell cycle checkpoints in overcoming low-dose hyper-radiosensitivity (HRS) has been proposed, the underlying mechanism of HRS in human hepatocellular cells remains unclear. Therefore, the aim of this study was to characterize HRS inhuman hepatocellular HepG2 cells and to explore the...

journal_title：International journal of radiation biology

authors： Xue J,Zong Y,Li PD,Wang LX,Li YQ,Niu YF

更新日期：2016-10-01 00:00:00

abstract：:DNA double-strand break (dsb) induction in diploid yeast was measured by neutral sucrose sedimentation after exposure to very heavy ions with values of linear energy transfer (LET) ranging from about 300 to 11500 ke V/microns. Linear fluence dependencies were found in all cases from which dsb production cross-sections...

journal_title：International journal of radiation biology

authors： Akpa TC,Weber KJ,Schneider E,Kiefer J,Frankenberg-Schwager M,Harbich R,Frankenberg D

更新日期：1992-09-01 00:00:00

abstract：PURPOSE:The present study was designed to reveal, whether the 30 min daily full body exposure of mice to an inhomogeneous static magnetic field (SMF) has a statistically significant effect on diabetic neuropathy. MATERIALS AND METHODS:Three different doses (100, 150, or 200 mg/kg) of streptozotocin (STZ) were administ...

journal_title：International journal of radiation biology

authors： László JF,Szilvási J,Fényi A,Szalai A,Gyires K,Pórszász R

更新日期：2011-01-01 00:00:00

abstract：PURPOSE:To investigate whether an adaptive response can be induced in mice which were pre-exposed to 900 MHz radiofrequency fields. MATERIALS AND METHODS:Adult male Kunming mice were exposed to 900 MHz radiofrequency fields (RF) at power intensities of 12, 120 and 1200 μW/cm(2) for 1 h/day for 14 days and then subject...

journal_title：International journal of radiation biology

authors： Cao Y,Xu Q,Jin ZD,Zhou Z,Nie JH,Tong J

更新日期：2011-07-01 00:00:00

abstract：PURPOSE:Despite proven antitumor activity of gemcitabine in chemoradiotherapy of advanced head and neck cancer, many authors refer to severe acute and late local and haematological toxicity. Fludarabine does imply nearly the same mechanisms of action as gemcitabine, inhibiting various enzymes involved in DNA replicatio...

journal_title：International journal of radiation biology

authors： Nitsche M,Christiansen H,Hermann RM,Lucke EM,Peters K,Rave-Frank M,Schmidberger H,Pradier O

更新日期：2008-08-01 00:00:00