Bone quality in adults with severe motor and intellectual disabilities.

Abstract:

OBJECTIVE:To determine bone quality in adults with severe motor and intellectual disabilities. DESIGN:A retrospective cohort study. PATIENTS:Bone quality of 60 patients with severe motor and intellectual disabilities (28 men, 32 women; mean age 57 years) at a long-term care facility for adults was examined retrospectively. METHODS:Quantitative ultrasonography was used to measure the stiffness index, T-score and Z-score of the calcaneus. A multiple linear regression model, including sex, age, anti-epileptic drug use, tube-feeding status, and current and peak physical abil-ities, was used to identify significant predictors of T-scores. RESULTS:Quantitative ultrasonography revealed that all patients had lower bone quality (based on T-scores, Z-scores, and stiffness index), and all patients had T-scores with standard deviations (SD) below 1.8. Current physical ability, age, and anti-epileptic drug use were significant factors in T-score determination, while tube-feeding and peak physical ability were not. The ability to walk without assistance was the most significant predictor in quantitative ultrasonography. CONCLUSION:Severely low bone quality is observed in patients with severe motor and intellectual disabilities; and it is strongly associated with current physical activity. It is important that patients with severe motor and intellectual disabilities preserve their physical abilities to prevent osteoporosis-related fractures.

journal_name

J Rehabil Med

authors

Sakai T,Shirai T,Oishi T

doi

10.2340/16501977-2789

subject

Has Abstract

pub_date

2021-01-15 00:00:00

eissn

1650-1977

issn

1651-2081

pub_type

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