Abstract:
:The suppression of elements associated with wound contracture and unfavorable scarring is a potentially important strategy in clinical wound management. In this study, the presence of α smooth muscle actin (αSMA), a protein involved in wound contraction, was analyzed in a series of wounds in which bovine fetal collagen (BFC) acellular dermal matrix (PriMatrix) was used in staged split thickness skin graft procedures. The results obtained through histological and quantitative image analyses of incidental biopsies from these wounds demonstrated a suppression of αSMA in the wound regions occupied by assimilated BFC relative to increased levels of αSMA found in other areas of the wound. The αSMA levels found in assimilated BFC were similar to αSMA levels in uninjured human dermis. These findings suggest a mechanism by which application of BFC could decrease contraction of full thickness skin wounds.
journal_name
Ann Plast Surgjournal_title
Annals of plastic surgeryauthors
Lineaweaver W,Bush K,James Kdoi
10.1097/SAP.0000000000000449subject
Has Abstractpub_date
2015-06-01 00:00:00pages
S255-8eissn
0148-7043issn
1536-3708journal_volume
74 Suppl 4pub_type
杂志文章abstract::Microvascular reconstruction at the lower extremity for complex composite wounds has traditionally been predicated upon performance of the microanastamosis beyond the so-called "zone of injury." Failure to do so was believed to account for increased rates of vessel thrombosis and transplant loss. Extensive vessel diss...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199603000-00007
更新日期:1996-03-01 00:00:00
abstract::Despite many advances in reconstructive techniques, the full-thickness scalp defect remains a difficult problem for the reconstructive surgeon. Patient and disease-specific factors occasionally make reconstruction with a dermal regeneration template (DRT) an attractive option when other methods are less advised. Altho...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e318243390b
更新日期:2012-05-01 00:00:00
abstract::The most common cause of nasal obstruction is chronic enlargement of the inferior turbinate bones. The variety of medical and surgical treatments available for this condition bears testimony to their frequent ineffectiveness and the frustration of the physician or surgeon caring for these patients. Removal or destruct...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-197909000-00009
更新日期:1979-09-01 00:00:00
abstract::This article discusses a method of reconstruction of breast crease for correction of postoperative deformities. These deformities are usually the result of implant insertion for the purpose of breast enlargement or reconstruction. The operation is performed by creating a new crease in the appropriate site by suturing ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-200103000-00013
更新日期:2001-03-01 00:00:00
abstract::Noma is primarily affecting children in underprivileged countries and results in disfiguring facial defects, loss of mandibular movement, and subsequent social disintegration. Plastic surgery in West Africa traditionally uses pedicled flaps. In large, complex, or central facial defects, though, pedicled flaps are apt ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/01.sap.0000165688.50780.e9
更新日期:2005-08-01 00:00:00
abstract::A rigid transparent face mask of cellulose acetate butyrate was developed for the control of scar hypertrophy in the burned face. Excellent patient acceptance has been found in a six-year series of 97 patients. Use of the device for at least twenty hours a day for an average of one and a half years per patient has ena...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-198103000-00014
更新日期:1981-03-01 00:00:00
abstract::Oxygen free radicals are implicated to cause tissue injury during ischemia and reperfusion and may play a central role in the no-reflow phenomena. Modulation of these substances has been suggested as a means of decreasing the amount of tissue loss due to ischemia and subsequent reperfusion. Pretreatment of tissues wit...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199202000-00008
更新日期:1992-02-01 00:00:00
abstract:BACKGROUND:Historically, dissection of the temporoparietal fascia immediately above the zygomatic arch has been avoided due to the risk of transection of the temporofrontal rami of the facial nerve. METHODS:A total of 8 fresh cadaveric hemi-faces have been dissected to investigate the relationship of the temporofronta...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e318221b563
更新日期:2012-06-01 00:00:00
abstract::Congenital absence of the vagina was repaired in twenty patients; the longest follow-up was seventeen years. The surgical method is described, including the skin graft, the sculpted prosthesis, and the mechanic's waste bolus for retention. The patient must be oriented thoroughly before the operation. Even with an opti...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-197807000-00004
更新日期:1978-07-01 00:00:00
abstract::The successful release of severe contracture of the first web space depends on addition of a sufficient amount of skin. Because local skin is limited, skin grafts tend to contract, and free and pedicle flaps are bulky, further procedures are often obligatory. Expansion of the tissues of the dorsum of the hand offers a...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199105000-00009
更新日期:1991-05-01 00:00:00
abstract::Augmentation and corrective malarplasty are relatively new procedures that require careful preoperative evaluation to ensure that the effect produced will blend harmoniously with the existing facial structure. A variety of implant types and materials are available to accommodate varying needs, and several surgical app...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-197904000-00008
更新日期:1979-04-01 00:00:00
abstract:BACKGROUND:Scalp defects can be reconstructed either with skin graft, local flaps, free flaps, or tissue expansion. Tissue expanders have been proved to be fruitful in the pediatric population. Scalp expansion has proved to be useful in the reconstruction of posttraumatic and postburn alopecic defects. Selective nerve ...
journal_title:Annals of plastic surgery
pub_type: 临床试验,杂志文章
doi:10.1097/SAP.0000000000001227
更新日期:2018-02-01 00:00:00
abstract::Many techniques have been developed for the correction of eyelid ptosis. A new tarsal plate resection technique is described for use in cases of minimal ptosis with fair to good levator function. The procedure involves a horizontal lenticular excision of the tarsal plate, placed so that equal amounts of tarsus remain ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199007000-00002
更新日期:1990-07-01 00:00:00
abstract::CO2 laser has been used for the treatment of 22 patients with xanthelasma palpebrarum. This office procedure done under local anesthesia is fast and easy. The lipomatous yellow plaques are accurately photovaporized in a bloodless field, layer by layer, until the lesion is totally eradicated. The treated area heals by ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199312000-00005
更新日期:1993-12-01 00:00:00
abstract::We report 2 patients with paraspinous sarcoma treated with omental transposition tunneled through a defect in the lumbar fascia that resurfaced in the soft tissues of the lower back. Traditional reconstruction with skin flaps was unsatisfactory because of prior irradiation to the area. In 1 patient the omentum obliter...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199312000-00015
更新日期:1993-12-01 00:00:00
abstract:PURPOSE:Periarterial sympathectomy is a treatment option for patients with systemic sclerosis (SSc) suffering from digital vasculopathy. Despite potential benefits of ulcer healing, pain improvement, and amputation prevention, this operation appears to be infrequently performed. The aims of our study are as follows: (1...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000000614
更新日期:2015-12-01 00:00:00
abstract:BACKGROUND:In our previous study, we used cross finger fascial flap combined with split-thickness toe nail bed graft to reconstruct large area defect of the nail bed with distal phalanx exposure. Fingertip avulsions are common injuries to the upper extremity and cause a great deal of distress for patients. Replantation...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000002002
更新日期:2019-12-01 00:00:00
abstract::The optic nerve can be injured indirectly by blunt trauma to the frontoorbital region. The mechanism of injury is related to trauma of the nerve in the tight, bony optic canal. Neurovisual transmission in the canal is interrupted by pressure on the nerve. The conventional management includes careful observation and su...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-197811000-00011
更新日期:1978-11-01 00:00:00
abstract::Many surgical procedures to improve mandibular contour have been introduced in East Asia. Despite consensus regarding mandible contouring surgery, surgery which includes angle ostectomy and lateral cortex excision, some patients require only mandibular angle ostectomy. The intraoral approach is a widely used method, b...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000000216
更新日期:2016-01-01 00:00:00
abstract::Five patients with arteriovenous malformations of the face (4 males and 1 woman; age range, 11-38 years) were treated by selective embolization through the feeding arteries with polyvinyl alcohol particles. Immediate gross angiographical obliteration was obtained in 4 patients, with pronounced reduction of the arterio...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:
更新日期:1992-06-01 00:00:00
abstract::We propose that, the face should be regarded as an organ. We compare the anatomic structure and functions of the face with those of the kidney, one of the most commonly transplanted solid organs. Composite tissue allografts demonstrated to improve the quality of life. Although not classified as a life-essential transp...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e3181844ea3
更新日期:2008-09-01 00:00:00
abstract::The secondary correction of facial asymmetry due to early posterior cranial deformation is presented. The combination of mandibular skeletal reduction of the gonial angle and inferior border, masseter muscle thinning, and auricular setback can be an effective camouflage technique when the facial skeleton and occlusion...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199211000-00018
更新日期:1992-11-01 00:00:00
abstract::We present 8 cases of microvascular reconstruction of the pharynx and cervical esophagus using 5 free ileal transfers and 3 radial forearm flaps. One of the skin flaps underwent a delay procedure a month before transfer. All flaps survived, though there were 2 salivary fistulas that healed spontaneously. ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199311000-00010
更新日期:1993-11-01 00:00:00
abstract::Sarcoidosis is a systemic disease of unknown etiology that is characterized by noncaseating granulomatous inflammation of various organs. Isolated nasal cutaneous involvement is very uncommon (0.3%-4.0% of the patients reported) and rarely do sarcoid lesions present as severe nasal deformities and surgical treatment i...
journal_title:Annals of plastic surgery
pub_type: 杂志文章,评审
doi:10.1097/SAP.0b013e3181b4051b
更新日期:2010-06-01 00:00:00
abstract::During this experiment the authors investigated whether prolonged local use of verapamil or lidocaine prevents vasoconstriction and establishes better blood supply to the rat epigastric skin flap, hence reducing the necrosis that occurs otherwise. Abdominal wall skin flaps of 45 Sprague-Dawley rats, based on a single ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-199909000-00010
更新日期:1999-09-01 00:00:00
abstract::This reconstructive microsurgery course will run yearly and was borne and popularized from its infant meeting the year before, primarily focused on perforator flaps. It is a 2-day course updating residents/registrars to attending physicians/consultants about the most topical advancements in microvascular reconstructiv...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0000000000000824
更新日期:2017-01-01 00:00:00
abstract::A technique for reconstruction of the bilateral cleft lip nose is described. The literature for bilateral cleft lip nasal repair and the use of autogenous cartilage grafts is reviewed. ...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/00000637-197905000-00003
更新日期:1979-05-01 00:00:00
abstract::It has been reported that breastfeeding problems occur in women who have breast implants. The breastfeeding success of women who had augmentation with saline implants and subsequently had a live birth (n = 107) was compared with that of women of similar age who had hypoplastic breasts and had children before their con...
journal_title:Annals of plastic surgery
pub_type: 杂志文章
doi:10.1097/SAP.0b013e3181c925e4
更新日期:2010-05-01 00:00:00
abstract::Parry first described the syndrome of progressive facial atrophy in 1825, followed by Romberg in 1846. The clinical hallmark of the syndrome is atrophy of the facial soft tissues, including fat and muscle as well as underlying bone. Clinicians have classically reserved treatment until the end of the disease process, a...
journal_title:Annals of plastic surgery
pub_type: 杂志文章,评审
doi:10.1097/SAP.0b013e31820b3aa8
更新日期:2011-10-01 00:00:00
abstract::Changes in skin sensibility occur in various postoperative plastic surgeries, especially when they involve major skin and subcutaneous dissection. There were no studies so far that objectively compared changes of ear sensibility. This prospective study was conducted to compare ear sensibility before and after otoplast...
journal_title:Annals of plastic surgery
pub_type: 临床试验,杂志文章
doi:10.1097/SAP.0b013e31820bcc11
更新日期:2012-02-01 00:00:00