Changes in glycoprotein fucosylation in a concanavalin A-resistant variant of a human leukemia cell line (K562).

abstract：:Colorectal cancer (CRC) is known as the third most common and fourth leading cancer associated death worldwide. The occurrence of metastasis has remained as a critical challenge in CRC, so that distant metastasis (mostly to the liver) has been manifested in about 20%-25% of patients. Several screening approaches have ...

journal_title：Journal of cellular biochemistry

authors： Sarvizadeh M,Ghasemi F,Tavakoli F,Sadat Khatami S,Razi E,Sharifi H,Biouki NM,Taghizadeh M

更新日期：2019-06-01 00:00:00

abstract：:Emerging evidence suggests that long noncoding RNAs (lncRNAs) are involved in many biological processes, such as cell growth, differentiation, apoptosis, and autophagy. Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1), highly expressed in endothelial cells, is well conserved and implicated in endothelia...

journal_title：Journal of cellular biochemistry

authors： Li S,Pan X,Yang S,Ma A,Yin S,Dong Y,Pei H,Bi X,Li W

更新日期：2019-03-01 00:00:00

abstract：:Poor clinical outcomes of tendon repair, together with limited regenerative capacity of the tissue, have triggered the search for alternative regenerative medicine strategies. Human adipose-derived stem cells (hASCs) are being investigated as a promising cell source in contributing for tendon repopulation and reconstr...

journal_title：Journal of cellular biochemistry

authors： Costa-Almeida R,Berdecka D,Rodrigues MT,Reis RL,Gomes ME

更新日期：2018-04-01 00:00:00

abstract：:The mitochondrial antioxidant enzyme Mn-Superoxide Dismutase (Sod2) is essential for mammalian survival. I82T mutation in human Sod2 has been linked to a wide variety of diseases, including Alzheimer's and Parkinson's diseases as well as some types of cancers. Yeast wild-type (WT) Sod2 and the mutant Sod2 I91T, which ...

journal_title：Journal of cellular biochemistry

authors： de Carvalho MD,De Mesquita JF,Eleutherio EC

更新日期：2017-05-01 00:00:00

abstract：:The pro-oxidant effect of L-ascorbic acid (LAA) is toxic to leukemia cells. LAA induces the oxidation of glutathione to its oxidized form (GSSG) and this is followed by a concentration-dependent H(2)O(2) accumulation, which occurs in parallel to the induction of apoptosis. To identify early protein targets of LAA in l...

journal_title：Journal of cellular biochemistry

authors： Park S,Lee J,Yeom CH

更新日期：2006-12-15 00:00:00

abstract：:Protein phosphatase 2A (PP2A) is an important enzyme within various signal transduction pathways. The present study was investigated PP2A mediates JS-K-induced apoptosis by affecting Bcl-2 family protein. JS-K showed diverse inhibitory effects in five HCC cell lines, especially HepG2 cells. JS-K caused a dose- and tim...

journal_title：Journal of cellular biochemistry

authors： Liu L,Huang Z,Chen J,Wang J,Wang S

更新日期：2018-08-01 00:00:00

abstract：:Excessive plasma triglyceride (TG) and cholesterol levels promote the progression of several prevalent cardiovascular risk factors, including atherosclerosis, which is a leading death cause. Perilipin 5 (Plin5), an important perilipin protein, is abundant in tissues with very active lipid catabolism and is involved in...

journal_title：Journal of cellular biochemistry

authors： Zhou PL,Li M,Han XW,Bi YH,Zhang WG,Wu ZY,Wu G

更新日期：2019-11-01 00:00:00

abstract：:Endometrial cancer is one of the most common gynecological malignant tumors. The roles of competing endogenous RNAs (ceRNAs) in this disease, however, remain unclear. In this study, we constructed a ceRNA network to reveal the core ceRNAs in endometrial cancer. Differentially expressed genes were summarized from The C...

journal_title：Journal of cellular biochemistry

authors： Wang Y,Huang T,Sun X,Wang Y

更新日期：2019-11-01 00:00:00

abstract：:Among ciliates, Paramecium has become a privileged model for the study of "species problem" particularly in the case of the "Paramecium aurelia complex" that has been intensely investigated. Despite extensive studies, the taxonomy of Paramecium is still challenging. The major problem is an uneven sampling of Parameciu...

journal_title：Journal of cellular biochemistry

authors： Tasneem F,Shakoori FR,Ilyas M,Shahzad N,Potekhin A,Shakoori AR

更新日期：2019-11-06 00:00:00

abstract：:Alzheimer's disease, a neurodegenerative disorder continues to be an area of investigation by the international researchers' fraternity. Despite all the ongoing efforts, the effective set of promising cholinesterase inhibitors available in the market for patients' use is limited. Furthermore, the currently available d...

journal_title：Journal of cellular biochemistry

authors： Shakil S

更新日期：2019-02-11 00:00:00

abstract：BACKGROUND:Acinetobacter baumannii has emerged as a major cause of nosocomial infections. Various resistance mechanisms of A. baumannii against antibiotics have transformed it into a successful nosocomial pathogen. Because of the limited number of available antibiotics, we used a medicinal plant with an antibacterial e...

journal_title：Journal of cellular biochemistry

authors： Hassannejad N,Bahador A,Rudbari NH,Modarressi MH,Parivar K

更新日期：2019-11-01 00:00:00

abstract：:Ginsenoside Rg1 is a major active ingredient of Panax notoginseng radix which has demonstrated a number of pharmacological actions including a cardioprotective effect in vivo. This study investigated the protective effect and mechanism of ginsenoside Rg1 in cardiomyocytes hypoxia/reoxygenation (H/R) model. Pretreatmen...

journal_title：Journal of cellular biochemistry

authors： Zhu D,Wu L,Li CR,Wang XW,Ma YJ,Zhong ZY,Zhao HB,Cui J,Xun SF,Huang XL,Zhou Z,Wang SQ

更新日期：2009-09-01 00:00:00

abstract：:Proper bone remodeling requires an active process of angiogenesis which in turn supplies the necessary growth factors and stem cells. This tissue cooperation suggests a cross-talk between osteoblasts and endothelial cells. This work aims to identify the role of paracrine communication through vascular endothelial grow...

journal_title：Journal of cellular biochemistry

authors： Grellier M,Ferreira-Tojais N,Bourget C,Bareille R,Guillemot F,Amédée J

更新日期：2009-02-15 00:00:00

abstract：BACKGROUND/AIMS:Fibroblast growth factor 21 (FGF21) plays a protective role in ischemia/reperfusion induced cardiac injury. However, the exact molecular mechanism of FGF21 action remains unclear. This study was designed the protective effect of FGF21 on the heart and its mechanism. METHOD:Adenovirus vector expressing ...

journal_title：Journal of cellular biochemistry

authors： Sun M,Jin L,Bai Y,Wang L,Zhao S,Ma C,Ma D

更新日期：2019-12-01 00:00:00

abstract：:The activity of S6 kinases (S6K) is highly induced in cancer cells highlighting an essential role in carcinogenesis. The S6K family has two members: S6K1 and S6K2 which bear common as well as distinct features. In an attempt to identify S6K2 unique sequence features compared to S6K1, we applied extensive bioinformatic...

journal_title：Journal of cellular biochemistry

authors： Ismail HM,Hurd PJ,Khalil MI,Kouzarides T,Bannister A,Gout I

更新日期：2014-06-01 00:00:00

abstract：:During inflammation, overproduction of nitric oxide (NO) can damage chondrocytes. In this study, we separately evaluated the toxic effects of exogenous and endogenous NO on human chondrocytes and their possible mechanisms. Human chondrocytes were exposed to sodium nitroprusside (SNP), an NO donor, or a combination of ...

journal_title：Journal of cellular biochemistry

authors： Wu GJ,Chen TG,Chang HC,Chiu WT,Chang CC,Chen RM

更新日期：2007-08-15 00:00:00

abstract：:The Zika virus is a rapidly spreading Aedes mosquito-borne sickness, which creates an unanticipated linkage birth deformity and neurological turmoil. This study represents the use of the combinatorial immunoinformatics approach to develop a multiepitope subunit vaccine using the structural and nonstructural proteins o...

journal_title：Journal of cellular biochemistry

authors： Kumar Pandey R,Ojha R,Mishra A,Kumar Prajapati V

更新日期：2018-09-01 00:00:00

abstract：:The role of excision repair cross-complimentary group 1 (ERCC1) gene polymorphisms in breast and ovarian cancer development has long been controversial and existing data were inconsistent. Here, we conducted a comprehensive meta-analysis to better clarify the association. Case-control studies published from December 2...

journal_title：Journal of cellular biochemistry

authors： Yang F,Mu X,Bian C,Zhang H,Yi T,Zhao X,Lin X

更新日期：2019-09-01 00:00:00

abstract：:The lysosomal cysteine protease cathepsin B is implicated in degradation of extracellular matrix (ECM), a crucial step in a variety of physiological and pathological processes, including tumor dissemination and angiogenesis. In this study, we analyzed the contribution of extracellular and intracellular cathepsin B act...

journal_title：Journal of cellular biochemistry

authors： Premzl A,Turk V,Kos J

更新日期：2006-04-15 00:00:00

abstract：:In a previous study, we have shown that the gene promoter of a protein termed KIAA0082 is regulated by interferon and that this protein interacts with the RNA polymerase II. It has been subsequently shown that KIAA0082 is the human cap-specific messenger RNA (mRNA) (nucleoside-2'-O-)-methyltransferase 1 (hMTr1), which...

journal_title：Journal of cellular biochemistry

authors： Simabuco FM,Pavan ICB,Pestana NF,Carvalho PC,Basei FL,Campos Granato D,Paes Leme AF,Zanchin NIT

更新日期：2019-04-01 00:00:00

abstract：:X-ray atomic structure of recombinant Hell's gate globin I (HGbI) from Methylacidophilum infernorum was calculated from the X-ray diffraction data of two different types of crystals: obtained by classical hanging drop and by LB nanotemplate method under the same crystallization conditions. After the accurate compariso...

journal_title：Journal of cellular biochemistry

authors： Pechkova E,Scudieri D,Belmonte L,Nicolini C

更新日期：2012-07-01 00:00:00

abstract：:We aimed to understand whether metformin imposes the inhibitory effect on the HBV-associated tumorigenesis by regulating the HULC and its downstream signaling pathway. Luciferase assay, RT-PCR, and Western-blot, MTT and flow cytometry analysis were performed to understand and the mechanism, by which metformin enhance ...

journal_title：Journal of cellular biochemistry

authors： Jiang Z,Liu H

更新日期：2018-06-01 00:00:00

abstract：:Little is known about how adhesion molecules on APCs accumulate at immunological synapses. We show here that ICAM-1 on APCs is continuously internalized and rapidly recycled back to the interface after antigen-priming T-cell contact. The internalization rate is high in APCs, including Raji B cells and dendritic cells,...

journal_title：Journal of cellular biochemistry

authors： Jo JH,Kwon MS,Choi HO,Oh HM,Kim HJ,Jun CD

更新日期：2010-12-01 00:00:00

abstract：:The proto-oncogenes c-fos and c-jun have been shown in numerous model systems to be induced within minutes of growth factor stimulation, during the G0/G1 transition. In this report we use the mitotic shake-off procedure to generate a population of highly synchronized Swiss 3T3 cells. We show that both of these immedia...

journal_title：Journal of cellular biochemistry

authors： Cosenza SC,Yumet G,Soprano DR,Soprano KJ

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND:Curcuminoids are polyphenols with documented anti-inflammatory activity and has been shown to improve the symptoms of several inflammatory diseases. We aimed to evaluate the effectiveness of a nanoformulation of curcuminoids in the treatment of ulcerative colitis. METHODS:This randomized double-blinded cont...

journal_title：Journal of cellular biochemistry

authors： Masoodi M,Mahdiabadi MA,Mokhtare M,Agah S,Kashani AHF,Rezadoost AM,Sabzikarian M,Talebi A,Sahebkar A

更新日期：2018-11-01 00:00:00

abstract：:Hepatic copper levels differ among patients with Wilson disease (WD) and normal individuals depending on the dietary intake, copper bioavailability, and genetic factors. Copper chloride (CuCl2 ) caused dose-dependent reduction in cell viability of human teratocarcinoma (HepG2) cell line, measured using the 3-(4,5-dime...

journal_title：Journal of cellular biochemistry

authors： Agnihotry S,Dhusia K,Srivastav AK,Upadhyay J,Verma V,Shukla PK,Ramteke PW,Gautam B

更新日期：2019-11-01 00:00:00

abstract：:Toxoplasma gondii excreted-secreted antigens (ESA) could lead to the fetal abortion especially in the early stage of pregnancy. Deficit in regulatory T cells is a critical event in the fetal abortion. Transcription factor forkhead box p3 (Foxp3) mediates differentiation and functional roles on regulatory T cells. Prev...

journal_title：Journal of cellular biochemistry

authors： Chen J,Huang C,Zhu D,Chen L,Wang J,Sun X,Hu L,Duan Y

更新日期：2018-12-01 00:00:00

abstract：:To evaluate the diagnosis and prognosis of the tumor microenvironment (immunization and stromal cells) in kidney renal clear cell carcinoma (KIRC), KIRC cases selected from The Cancer Genome Atlas database were divided into two groups according to the ESTIMATE algorithm-derived immune scores. Our data suggested that t...

journal_title：Journal of cellular biochemistry

authors： Li S,Xu W

更新日期：2019-11-07 00:00:00

abstract：:c-fos gene has a close relationship with the osteoblasts. Mechanical signal effect on osteoblasts would change the expression level of c-fos. Authors introduce the signal pathways of four cis-response elements on the promoter of c-fos, that is, CRE (cAMP responsive element), FAP-1 (Fbs-AP-1 site), SRE (serum response ...

journal_title：Journal of cellular biochemistry

authors： He H,Ping F

更新日期：2009-04-01 00:00:00

abstract：:We have incorporated antibodies against fibronectin or laminin into liposomes and studied their interaction with insoluble forms of these antigens. The antibodies, after modification by palmitoylchloride, were incorporated into the lipid bilayer by the cholate dialysis method. The antibodies in the liposomes recognize...

journal_title：Journal of cellular biochemistry

authors： Torchilin VP,Klibanov AL,Ivanov NN,Gluckhova MA,Koteliansky VE,Kleinman HK,Martin GR

更新日期：1985-01-01 00:00:00