Human insulin. Its development and clinical use.

abstract：OBJECTIVE:There is a need to identify safe and effective opioid-sparing multimodal alternative treatment strategies and approaches, including topical analgesics, for opioid-experienced chronic pain patients to mitigate the risk of addiction, misuse, and abuse of opioids. METHODS:This subset analysis from a prospective...

journal_title：Postgraduate medicine

authors： Gudin JA,Brennan MJ,Harris ED,Hurwitz PL,Dietze DT,Strader JD

更新日期：2018-01-01 00:00:00

abstract：:The fact that the national death rate from carcinoma of the colon and rectum has remained static over the past two decades is strong incentive for future investigation of measures to allow detection in its early and more favorable stage. Although no significant improvements in surgical techniques have afforded improve...

journal_title：Postgraduate medicine

authors： Bland KI,Garrison RN,Knutson CO

更新日期：1979-09-01 00:00:00

abstract：:Inhaled corticosteroids (ICSs) belong to the armament for treatment of chronic obstructive pulmonary disease (COPD) and as such, they are widely used in real life. This is a narrative review on evidence-based papers published in the English language listed in Medline between 1990 and March 2016 discussing ICS applicat...

journal_title：Postgraduate medicine

authors： Andreeva-Gateva PA,Stamenova E,Gatev T

更新日期：2016-06-01 00:00:00

abstract：:The tools and methods of epidemiology, particularly the clinical trial, help guide the clinical practice of medicine. Dr Gorelick reviews the results of major clinical trials for prevention of transient cerebral ischemia and atherothrombotic stroke and assesses the effect of these findings on treatment. ...

journal_title：Postgraduate medicine

authors： Gorelick PB

更新日期：1989-12-01 00:00:00

abstract：:Although uncommon, hypertensive emergencies require prompt recognition and treatment to reduce very high morbidity and mortality rates. Admission to an intensive care unit for treatment and monitoring is essential for optimal care. A Swan-Ganz catheter is often helpful in management. Intravenous nitroprusside sodium (...

journal_title：Postgraduate medicine

authors： Smith CB,Flower LW,Reinhardt CE

更新日期：1991-04-01 00:00:00

abstract：:Peripheral neuropathy may be a minor, even unrecognized, clinical problem, or it may be severe and virtually disabling. As in any chronic disorder, the physician's role is to look for treatable disease and to teach patients about the symptoms and natural history of the dysfunction as well as methods for coping with i...

journal_title：Postgraduate medicine

authors： Riley TL,Massey EW

更新日期：1980-10-01 00:00:00

abstract：:It is now possible to mimic normal insulin action more precisely than ever before with physiologic treatment programs using self-monitoring of blood glucose levels and newer insulins with more predictable action. Physiologic programs are more effective for both insulin-dependent (type I) and non-insulin-dependent (typ...

journal_title：Postgraduate medicine

authors： Beaser RS

更新日期：1992-03-01 00:00:00

abstract：:Abdominal paracentesis is a useful and safe technique in the evaluation of ascites. The withdrawn ascitic fluid should be routinely analyzed for appearance, blood cell count, and amylase and total protein concentrations; examined cytologically; and cultured. Results should either substantiate the clinical diagnosis or...

journal_title：Postgraduate medicine

authors： Babb RR

更新日期：1978-05-01 00:00:00

abstract：:Five common conditions and several less common ones cause eyelid dermatitis. Diagnosis and treatment depend on recognizing their characteristics, obtaining a good history, performing a careful skin examination, administering and interpreting patch tests, prescribing the proper medications at the right time, and teachi...

journal_title：Postgraduate medicine

authors： Parkinson RW

更新日期：1996-08-01 00:00:00

abstract：:Allergy is responsible for many problems in the pediatric age-group. At times the most difficult job for the physician is to determine if the patient is indeed allergic and, if so, to what. Allergy skin testing remains the first choice for diagnostic study. Treatment consists of avoiding the offending allergen if poss...

journal_title：Postgraduate medicine

authors： Hein EW,Kishore R

更新日期：1984-05-01 00:00:00

abstract：:Preview Congestive heart failure (CHF) is a common and serious problem, and its diagnosis and treatment should not be the exclusive province of the cardiologist. Primary care physicians can very adequately manage most cases in a cost-effective manner. In this article, Dr Seager gives guidelines for a standard approach...

journal_title：Postgraduate medicine

authors： Seager LH

更新日期：1995-11-01 00:00:00

abstract：:Physicians need to be aware that women and mothers are capable of sexually abusing children and need to watch for signs that a mother may be at risk for perpetrating abuse or that a child may have been abused. Posttraumatic stress disorder, attention-deficit hyperactivity disorder, secondary enuresis and encopresis, n...

journal_title：Postgraduate medicine

authors： Elliott AJ,Peterson LW

更新日期：1993-07-01 00:00:00

abstract：:Surgical intervention is usually indicated in reflux esophagitis when medical therapy fails to control symptoms. Since most patients with peptic esophagitis also have a sliding hiatal hernia, early procedures focused on hernia repair. Weakness of the lower esophageal sphincter is now known to be the pathogenetic mecha...

journal_title：Postgraduate medicine

authors： Woodward ER

更新日期：1977-02-01 00:00:00

abstract：:Benign essential tremor can be distinguished from parkinsonism by its rapid frequency, the involvement of voice and head, and the common finding of a positive family history. Essential tremor is less incapacitating than parkinsonism and less inexorably progressive. Propranolol (Inderal) is the best therapy available a...

journal_title：Postgraduate medicine

authors： Paulson GW

更新日期：1982-01-01 00:00:00

abstract：:In a series of 123 children with disorders of defecation, constipation was the main problem in 89 and fecal incontinence in 34. All but three of the latter also had constipation. The principal physical findings were abdominal protuberance with palpable stool in the bowel and the presence of a fecal mass in the rectal ...

journal_title：Postgraduate medicine

authors： Liebman WM

更新日期：1979-08-01 00:00:00

abstract：:A patient's history usually contains key information regarding the type of dizziness and the best way to direct diagnostic workup. In dizziness with a vestibular cause (benign positional vertigo, vestibular neuritis, Meniere's disease, migraine, vertebrobasilar insufficiency), patients often describe their world as sp...

journal_title：Postgraduate medicine

authors： Baloh RW

更新日期：1999-02-01 00:00:00

abstract：:While more remains to be learned about the natural history of deep vein thrombosis and pulmonary embolism, better information is now available on which to base decisions about diagnosis and treatment. Several retrospective and prospective studies have placed the value of lung scanning, venography, and pulmonary angiog...

journal_title：Postgraduate medicine

authors： Broaddus C,Matthay MA

更新日期：1986-03-01 00:00:00

abstract：:Management of the acutely poisoned patient should start with decontamination of the skin and irrigation of the eyes, if necessary, and assessment of cardiorespiratory status, neurologic status, and pupils and eye movement. If a definable toxic syndrome is present, the specific "antidote" should be given. If no such sy...

journal_title：Postgraduate medicine

authors： Saxena K,Kingston R

更新日期：1982-05-01 00:00:00

abstract：:Maternal peripartum complications continue to be a significant problem in the United States, even among previously healthy women. The problems include peripartum bleeding, infection, hypertension, and thromboembolic disease. Primary care physicians are often called upon to treat these conditions. An awareness of the a...

journal_title：Postgraduate medicine

authors： Ritter DC,deShazo RD

更新日期：1994-02-01 00:00:00

abstract：:Although the link between cigarette smoking and its cardiovascular effects is well established, the mechanisms through which smoking raises blood pressure remain to be clarified. Possible mechanisms include nicotine-induced peripheral and central sympathetic nervous system stimulation, persisting levels of nicotine in...

journal_title：Postgraduate medicine

authors： Kochar MS,Bindra RS

更新日期：1996-11-01 00:00:00

abstract：:With increased survival of increasing numbers of cancer patients as a result of therapy, the consequences, early and late, of the therapies must be realized. It is the treating physician's duty to preserve as much reproductive potential as possible for patients, consistent with adequate care. With radiotherapy this me...

journal_title：Postgraduate medicine

authors： Maguire LC

更新日期：1979-05-01 00:00:00

abstract：:Because new drugs continue to be developed, physicians treating patients with type 2 diabetes have a wide range of agents from which to choose. The newest class, the thiazolidinediones (TZDs), should be a mainstay of treatment for most patients with type 2 diabetes, because these agents reduce insulin resistance as we...

journal_title：Postgraduate medicine

authors： Bell DS

更新日期：2003-05-01 00:00:00

abstract：:The increased utilization of diagnostic procedures has prompted interest in cost-effective laboratory testing. Clinically useful tests-useful in the sense that the patient benefits-are cost effective. The choice of test(s) is determined by the risks and benefits of proposed management. In practice, the first step in c...

journal_title：Postgraduate medicine

authors： Burke MD

更新日期：1981-02-01 00:00:00

abstract：:Even modest alcohol ingestion can increase the risk of steatosis, and long-term, excessive consumption can lead to alcoholic hepatitis and eventually cirrhosis. Most patients with clinically significant alcoholic liver disease have histologic findings typical of all three conditions. The only clearly beneficial treatm...

journal_title：Postgraduate medicine

authors： Hill DB,Kugelmas M

更新日期：1998-04-01 00:00:00

abstract：:Patients with chronic obstructive lung disease (COLD) experience one or more episodes of acute respiratory failure in the late years of their illness. Initial evaluation is aimed at assessing the precipitating factor or factors as well as the severity of the acute episode and the need for intubation and mechanical ven...

journal_title：Postgraduate medicine

authors： Francis PB

更新日期：1986-01-01 00:00:00

abstract：:Ultraviolet (UV) radiation is a notorious environmental carcinogen. Acute and chronic UV radiation exposure increase the risk for skin cancer. Protecting oneself from both UVA and UVB radiation with broad-based sunscreen can prevent certain skin cancers, their precursors, and photoaging. Although sun protection factor...

journal_title：Postgraduate medicine

authors： Stechschulte SA,Kirsner RS,Federman DG

更新日期：2011-07-01 00:00:00

abstract：:Breast pain is a common, often distressing problem among women. After significant disease is ruled out, most patients respond to simple reassurance. Others, however, require treatment because symptoms interfere with their lifestyle. The authors offer practical suggestions for tailoring treatment for these patients acc...

journal_title：Postgraduate medicine

authors： Steinbrunn BS,Zera RT,Rodriguez JL

更新日期：1997-11-01 00:00:00

abstract：:The new oral anticoagulants have many advantages over vitamin K antagonists, but they are still associated with a troublesome incidence of major bleeding. Additionally, the absence of a reversal agent for the new oral anticoagulants is a barrier to their more widespread use. Currently, there are 3 potential reversal a...

journal_title：Postgraduate medicine

authors： Costin J,Ansell J,Laulicht B,Bakhru S,Steiner S

更新日期：2014-11-01 00:00:00

abstract：:Serum electrolyte levels by themselves may be difficult to interpret. For example, an abnormal serum potassium concentration cannot be understood without taking into account the patient's history, other serum electrolyte values, and possibly results of other laboratory tests. Knowledge of the principles of serum elect...

journal_title：Postgraduate medicine

authors： Kapsner CO,Tzamaloukas AH

更新日期：1991-12-01 00:00:00

abstract：:Why do some people spend most of the night tossing and turning while others drop off as quickly as a cat in the sun? There are many possible explanations for problems with falling and staying asleep and, sometimes, patients actually get a lot more sleep than they think they do. Each type of insomnia has its own set of...

journal_title：Postgraduate medicine

authors： Attarian HP

更新日期：2000-03-01 00:00:00