Sensitivity and specificity of first screen mammography in the Canadian National Breast Screening Study: a preliminary report from five centers.

Abstract:

:Sensitivity and specificity of first screen mammography in a randomized screening trial at five centers are reported. A total of 23,101 women underwent mammography; in 139, breast cancer was detected at first screening; in 20, less than 12 months after first screening; and in 47, at second screening. All 206 cancer cases were histologically confirmed, and 174 were defined as being detectable at first screening. Average length of follow-up for all women was 3.2 years. Interpretations of first screen mammograms by the center radiologists were matched to known outcomes. Simultaneous blind review was performed by a single reference radiologist with mammograms from all 206 cancer cases and those of a random sample of 739 women not known to have breast cancer at 15 months or more after initial screening. Overall, the five screening centers achieved a sensitivity of 69% (range, 60%-78%), a specificity of 94% (range, 93%-96%), a positive predictive value of 8.6% (range, 3%-16%), and a negative predictive value of 99.7% (range, 99.6%-99.9%).

journal_name

Radiology

journal_title

Radiology

authors

Baines CJ,Miller AB,Wall C,McFarlane DV,Simor IS,Jong R,Shapiro BJ,Audet L,Petitclerc M,Ouimet-Oliva D

doi

10.1148/radiology.160.2.3523590

subject

Has Abstract,Author List Incomplete

pub_date

1986-08-01 00:00:00

pages

295-8

issue

2

eissn

0033-8419

issn

1527-1315

journal_volume

160

pub_type

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