Abstract:
:Between December 1983 and August 1985, 110 cadaver transplants were performed at our institution. All were started on cyclosporine (CsA) and prednisone (P) for immunosuppressive therapy. Of the 110 patients, 46 were converted from CsA to azathioprine (AZA) for a variety of reasons (cost, toxicity, patient preference, prolonged dysfunction posttransplant, or nonresponsive rejection). The course and outcome of these patients are described. The only group of patients who had consistent benefit and stable course following the CsA-to-AZA switch were primary cadaver transplants with stable renal function (serum creatinine less than 2 mg/dl) who were converted an average of 7.97 months posttransplant. All other groups of patients had severe problems or graft loss postconversion.
journal_name
Transplantationjournal_title
Transplantationauthors
Gonwa TA,Nghiem DD,Schulak JA,Corry RJdoi
10.1097/00007890-198702000-00012subject
Has Abstractpub_date
1987-02-01 00:00:00pages
225-8issue
2eissn
0041-1337issn
1534-6080journal_volume
43pub_type
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