Abstract:
:Sixty-four cases of stage I vulvar squamous cell carcinoma were analyzed histologically to define a patient subset at minimum risk for recurrence or nodal metastases. Three patterns of invasion were predefined: carcinoma in situ with early stromal invasion (33%), pushing (8%), and infiltrative (59%). Infiltrative pattern and invasion deeper than 1.5 mm equally predicted nodal metastases (P = .045), although depth measurement in biopsy specimens was subject to sampling error. Confluence and absence of carcinoma in situ each predicted extranodal recurrence (P = .011). Local recurrence appeared more related to inadequate surgical margins than failure to perform radical vulvectomy. Carcinoma in situ with early stromal invasion represents a group at zero risk for nodal metastases. We recommend wide local excision for all stage I lesions. In general, omission of lymphadenectomy should be reserved for cases of carcinoma in situ with early stromal invasion.
journal_name
Obstet Gynecoljournal_title
Obstetrics and gynecologyauthors
Ross MJ,Ehrmann RLsubject
Has Abstractpub_date
1987-11-01 00:00:00pages
774-84issue
5eissn
0029-7844issn
1873-233Xjournal_volume
70pub_type
杂志文章abstract:BACKGROUND:Human immunodeficiency virus (HIV) lipodystrophy syndrome consists of insulin resistance, hyperlipidemia, increased waist-to-hip ratios, and relative hyperandrogenemia, which resembles polycystic ovary syndrome. CASE:A 30-year-old HIV-positive multipara with lipodystrophy syndrome had an elevated level of s...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/01.AOG.0000121832.02536.c3
更新日期:2004-05-01 00:00:00
abstract::A method of ablating the endometrium has been introduced into clinical practice that uses radiofrequency electromagnetic energy to heat the endometrium, using a probe inserted through the cervix. Preliminary studies suggest that over 80% of patients treated will develop either amenorrhea or a significant reduction in ...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/00006250-199011000-00032
更新日期:1990-11-01 00:00:00
abstract::A thorough inspection of the pelvis for adhesions was made at the time of laparoscopic tubal sterilization in 2131 patients. Contraceptive use was then compared in women with adhesions (cases) and those without adhesions (controls). Current or previous intrauterine device (IUD) use was not associated with a statistica...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1988-02-01 00:00:00
abstract:OBJECTIVE:To compare 12-hour and 72-hour expectant management of premature rupture of membranes (PROM) in singleton term pregnancies. METHODS:In a prospective, nonrandomized study, 566 low-risk women with singleton term pregnancies presenting with PROM were assigned to either 12-hour or 72-hour expectant management. P...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/0029-7844(95)00031-l
更新日期:1995-05-01 00:00:00
abstract::Eight gravidas with symptomatic polyhydramnios were managed with maternal indomethacin therapy. The mean gestational age at presentation was 28.6 +/- 3.5 weeks. Only patients requiring serial amniotic fluid decompressions for rapid amniotic fluid reaccumulation were enrolled in the study. An initial amniotic fluid dec...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1990-02-01 00:00:00
abstract::A pregnant patient with Eisenmenger's syndrome is reported. The hemodynamic data gathered during this pregnancy suggest that decreased peripheral vascular resistance and reflex bradycardia secondary to postural changes could be of extreme importance in contributing to the extremely high maternal mortality. Suggestions...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1977-07-01 00:00:00
abstract::A black multipara was shown, by hemoglobin electrophoresis, to have hemoglobin SD disease. The patient exhibited a typically mild anemia that probably was secondary to folate and iron deficiencies as well as to hemoglobinopathic hemolysis. The course of her pregnancy was complicated by pyelonephritis and hyposthenuria...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1982-09-01 00:00:00
abstract::Sixty-five infertile patients with moderate or severe endometriosis were treated with conservative surgery. Acosta's classification was used to demonstrate the extent of disease. In 48 women whose partners were normally fertile, 65% conceived, and in 17 whose partners were deficient, 35% achieved pregnancy. The extent...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1977-05-01 00:00:00
abstract::Ureaplasma urealyticum is a common inhabitant of the lower genital tract of women. It is unclear whether or not the microorganism plays a role in provoking spontaneous abortion. Reported is a U urealyticum infection of placenta and amniotic fluid in an immunologically competent host resulting in abruptio placentae and...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1986-08-01 00:00:00
abstract:OBJECTIVE:To determine the relationship between lower urinary tract symptoms and possible associated risk factors in women 40-60 years old. METHODS:In a normal population study, 502 women with lower urinary tract symptoms and 742 women with no symptoms (controls) were asked about possible associated factors. RESULTS:...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:2000-09-01 00:00:00
abstract::In order to ascertain the usefulness of urinary 17-ketosteroids (17-KS) in the evaluation of hirsutism, 28 paired determinations of 17-KS and serum androgens were performed in 26 hirsute women before (control) and after (post Dex) 7 days of dexamethasone (Dex) administration. Upper normal control and post Dex urinary ...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1977-04-01 00:00:00
abstract::Abortions by cervical dilatation with laminaria tents followed by placement of a metreurynter into the lower uterine cavity to provide a mechanical stretch (the method most often used in midterm abortions in Japan) was performed in 7 normal Japanese and American women, 19-24 weeks pregnant, to determine similarities ...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1973-05-01 00:00:00
abstract::A 1970 study by Fuertes-de la Haba et al. (Obstetrics and Gynecology 36: 597-602) on thromboembolism in Puerto Rican women taking oral contraceptives is criticized. Fuertes-de la Haba et al. interpreted their results as failing to corroborate previous publications indication an increased mortality rate from thrombo...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1971-09-01 00:00:00
abstract::Fifty-five patients at less than 36 weeks' gestation with severe toxemia were treated conservatively. The pregnancies were continued for a mean duration of 19.2 days and the mean gestation at delivery was 35.2 weeks. Fifty-three percent of the deliveries were by cesarean section. Of the neonates, 56.5% showed severe i...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1979-11-01 00:00:00
abstract:OBJECTIVE:To examine the association between gestational weight gain and perinatal outcome in women with gestational diabetes mellitus (GDM). METHODS:This is a retrospective cohort study of women with nonanomalous singleton pregnancies with GDM enrolled in the Sweet Success California Diabetes and Pregnancy Program be...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/AOG.0b013e31818b5dd9
更新日期:2008-11-01 00:00:00
abstract::Two hundred ten rats were randomized into one of five study groups to compare standard absorbable sutures with a new synthetic absorbable suture. We evaluated Maxon (polyglyconate), Vicryl (polyglactin), chromic catgut (catgut), and PDS (polydioxanone) with respect to tissue inflammatory reaction, knot security, sutur...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1988-03-01 00:00:00
abstract:OBJECTIVE:To compare biopsychologic profiles of women with dyspareunia with a matched no-pain control sample, and to determine whether dyspareunia subtypes based on physical findings have different psychosocial profiles from matched controls. METHODS:One hundred and five women with dyspareunia and 105 matched no-pain ...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/s0029-7844(98)80136-1
更新日期:1997-10-01 00:00:00
abstract::A total of 4517 successful antepartum nonstress tests (NST) was performed on 2003 high- (28%) and low- (72%) risk obstetric patients. Most patients were monitored from 32 to 34 weeks' gestation onward. A reactive NST was defined as 2 accelerations in 10 minutes--15 beats/min minimum amplitude; 15 seconds minimum durat...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/00006250-197907000-00006
更新日期:1979-07-01 00:00:00
abstract:OBJECTIVE:To evaluate the relationship among gestational age at elective cesarean delivery, neonatal intensive care unit (NICU) admission, and whether the presence of pre-cesarean delivery labor or ruptured membranes affected the incidence of neonatal respiratory distress. METHODS:A chart review was performed of all e...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/AOG.0b013e31816736e7
更新日期:2008-04-01 00:00:00
abstract::Two cases of thrombocytopenia, one resulting in bleeding, are reported in patients treated with prophylactic low-dose heparin. The evidence indicates that low-dose heparin was responsible. A review of the literature indicates that heparin-induced thrombocytopenia may be a common event. Since low-dose heparin has been ...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1978-07-01 00:00:00
abstract:OBJECTIVE:Among all women with pelvic inflammatory disease (PID), prevention of adverse reproductive consequences appears to be similarly achieved by outpatient treatment and inpatient treatment. We assessed whether outpatient is as effective as inpatient treatment in relevant age, race, and clinical subgroups of women...
journal_title:Obstetrics and gynecology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1097/01.AOG.0000175193.37531.6e
更新日期:2005-09-01 00:00:00
abstract:OBJECTIVE:To systematically review studies examining the relationship between hyperemesis gravidarum and Helicobacter pylori (H pylori) infection. DATA SOURCES:A 1966 to January 2007 search using MEDLINE/PubMed, EMBASE, and Web of Science included MeSH terms: "Helicobacter pylori," "Helicobacter infections," "hypereme...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章,评审
doi:10.1097/01.AOG.0000278571.93861.26
更新日期:2007-09-01 00:00:00
abstract::In experiments performed in anesthetized monkeys in the third trimester of pregnancy, mean maternal arterial blood pressure was continuously monitored, the uterine artery blood flow was measured with an electromagnetic flow probe, and prostaglandin levels were assayed in the uterine venous effluent. After inhibition o...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1977-11-01 00:00:00
abstract::The Apgar score provides an accepted and convenient method for reporting the status of the newborn infant immediately after birth and the response to resuscitation if needed. The Apgar score alone cannot be considered to be evidence of or a consequence of asphyxia, does not predict individual neonatal mortality or neu...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/AOG.0000000000001108
更新日期:2015-10-01 00:00:00
abstract::The use of the nitroblue tetrozolium (NRT) dye reduction test as a screening method for bacterial and fungal infections is now widely recognized. Levels have been reported to be falsely elevated in the pregnant state. This report includes a prospective study which showed that the results of this test in 124 pregnant w...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1975-03-01 00:00:00
abstract::A randomized prospective study compared the efficacy of a three-dose perioperative course of intravenously administered cefuroxime and metronidazole versus suction drainage of the vaginal vault for preventing postoperative infection in abdominal and vaginal hysterectomies. In vaginally operated patients, a significant...
journal_title:Obstetrics and gynecology
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1987-09-01 00:00:00
abstract::Imaging studies are important adjuncts in the diagnostic evaluation of acute and chronic conditions. However, confusion about the safety of these modalities for pregnant and lactating women and their infants often results in unnecessary avoidance of useful diagnostic tests or the unnecessary interruption of breastfeed...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章,实务指引
doi:10.1097/AOG.0000000000002350
更新日期:2017-10-01 00:00:00
abstract::Thirty-four patients using intrauterine contraceptive devices and experiencing excessive menstrual bleeding (more than 80 ml average loss for 2 cycles) were treated with the prostaglandin synthetase inhibitor naproxen. The trial was conducted according to a double-blind placebo-controlled crossover design. Each patien...
journal_title:Obstetrics and gynecology
pub_type: 临床试验,杂志文章
doi:
更新日期:1981-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the safety and efficacy of bremelanotide for the treatment of premenopausal women with hypoactive sexual desire disorder. METHODS:Two identical phase 3, randomized, double-blind, placebo-controlled, multicenter clinical trials (RECONNECT) evaluated the safety and efficacy of bremelanotide 1.75 mg...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1097/AOG.0000000000003500
更新日期:2019-11-01 00:00:00
abstract::Exercise, defined as physical activity consisting of planned, structured, and repetitive bodily movements done to improve one or more components of physical fitness, is an essential element of a healthy lifestyle, and obstetrician-gynecologists and other obstetric care providers should encourage their patients to cont...
journal_title:Obstetrics and gynecology
pub_type: 共识发展会议,杂志文章
doi:10.1097/AOG.0000000000003772
更新日期:2020-04-01 00:00:00