Treatment options for patients with stage D1 (T0-3,N1-2,M0) adenocarcinoma of prostate.

Abstract:

:Three hundred six patients with adenocarcinoma of the prostate underwent pelvic lymphadenectomy and had Stage D1 (T0-3,N1-2,M0) disease; 171 patients underwent radical retropubic prostatectomy with or without immediate adjuvant therapy (hormonal or radiation or both) or conservative (hormonal or radiation or both) treatment alone (n = 135). Follow-up was one-half to eighteen and one-half years (mean, 5 yrs). Immediate adjuvant orchiectomy significantly (P = 0.01) improved survival (87.4% at 10 years) and nonprogression rates for patients who underwent radical prostatectomy, but not for those who had lymphadenectomy. Overall patient survival was significantly better (P = 0.005) after prostatectomy than lymphadenectomy. Residual disease (n = 43) in patients who underwent prostatectomy and received adjuvant treatment (orchiectomy or radiation or both) did not affect disease outcome. Bilateral pelvic lymphadenectomy and radical prostatectomy with immediate adjuvant orchiectomy provided survival comparable to the expected survival; conservative treatment alone was associated with rapid disease progression and poor survival and significantly (P = 0.02) higher local morbidity.

journal_name

Urology

journal_title

Urology

authors

Zincke H,Utz DC,Thulé PM,Taylor WF

doi

10.1016/0090-4295(87)90290-1

subject

Has Abstract

pub_date

1987-10-01 00:00:00

pages

307-15

issue

4

eissn

0090-4295

issn

1527-9995

pii

0090-4295(87)90290-1

journal_volume

30

pub_type

杂志文章

相关文献

UROLOGY文献大全
  • Single system ectopic ureter to rectum subtending solitary kidney and bladder agenesis in newborn male.

    abstract::We report a case of a single system solitary ectopic ureter to the rectum with bladder agenesis in a viable newborn male. Only 2 cases of ectopic ureter to the rectum and 18 cases of bladder agenesis have been reported in viable newborns. To our knowledge, this case constitutes the first reported combination of these ...

    journal_title:Urology

    pub_type: 杂志文章

    doi:10.1016/j.urology.2006.09.048

    authors: Weight CJ,Chand D,Ross JH

    更新日期:2006-12-01 00:00:00

  • Robot-assisted radical cystectomy versus open radical cystectomy: a complete cost analysis.

    abstract:OBJECTIVES:To perform a complete cost analysis comparing robot assisted radical cystectomy (RARC) versus open radical cystectomy (ORC). MATERIAL AND METHODS:After institutional review board approval for data collection, we prospectively recorded perioperative outcomes and costs, such as hospital stay, transfusion rate...

    journal_title:Urology

    pub_type: 杂志文章

    doi:10.1016/j.urology.2010.07.502

    authors: Martin AD,Nunez RN,Castle EP

    更新日期:2011-03-01 00:00:00

  • Late hemorrhagic cystitis following low-dose cyclophosphamide therapy.

    abstract::Hemorrhagic cystitis is a recognized acute complication of cyclophosphamide (Cytoxan) therapy in the treatment of malignant disease. More recently, lower dose, long-term cyclophosphamide therapy has been used in the treatment of autoimmune diseases including rheumatoid arthritis. In 3 patients hemorrhagic cystitis dev...

    journal_title:Urology

    pub_type: 杂志文章

    doi:10.1016/0090-4295(79)90526-0

    authors: Marshall FF,Klinefelter HF

    更新日期:1979-12-01 00:00:00

  • Effect of vascular endothelial growth factor on regeneration of bladder acellular matrix graft: histologic and functional evaluation.

    abstract:OBJECTIVES:To evaluate the effect of vascular endothelial growth factor (VEGF) on regeneration of the bladder acellular matrix graft (BAMG). METHODS:A total of 40 female rats were divided into two groups. In the experimental group (VEGF+), the BAMG was incubated in VEGF and VEGF was injected into the host bladder. In ...

    journal_title:Urology

    pub_type: 杂志文章

    doi:10.1016/j.urology.2005.01.054

    authors: Youssif M,Shiina H,Urakami S,Gleason C,Nunes L,Igawa M,Enokida H,Tanagho EA,Dahiya R

    更新日期:2005-07-01 00:00:00

  • Neonatal adrenal hemorrhage manifesting as acute scrotum: timely diagnosis prevents unnecessary surgery.

    abstract::Neonatal adrenal hemorrhage presenting as scrotal swelling has been reported in 17 cases, with unnecessary surgical exploration in 7. We report 2 new cases, emphasizing the knowledge of this clinical association and the role of ultrasonography in the differential diagnosis for this specific condition and in all cases ...

    journal_title:Urology

    pub_type: 杂志文章

    doi:10.1016/s0090-4295(01)01610-7

    authors: Avolio L,Fusillo M,Ferrari G,Chiara A,Bragheri R

    更新日期:2002-04-01 00:00:00

  • Ureteral stenosis as the sole manifestation of Wegener's granulomatosis.

    abstract::In Wegener's granulomatosis, necrotizing lesions are typically located in the upper and lower respiratory tract and kidneys, and ureteral involvement is uncommon. We report 2 cases in which intrinsic ureteral stenosis was the sole manifestation of this small-vessel vasculitis. Excisional surgery evidenced characterist...

    journal_title:Urology

    pub_type: 杂志文章

    doi:10.1016/s0090-4295(03)00368-6

    authors: Kamar N,Malavaud B,Alric L,le Mao G,Mazerolles C,Duffaut M,Sarramon JP,Pourrat J

    更新日期:2003-08-01 00:00:00

  • Sacral Neuromodulation in Urological Practice.

    abstract::Sacral neuromodulation (SNM) is a minimally invasive, restorative treatment to improve voiding and elimination functions. We give a historical perspective of SNM and explore the evidence for the use of this therapy for Food and Drug Administration-approved pathologies as well as disease processes that are being treate...

    journal_title:Urology

    pub_type: 杂志文章,评审

    doi:10.1016/j.urology.2016.06.004

    authors: Liberman D,Ehlert MJ,Siegel SW

    更新日期:2017-01-01 00:00:00

  • Cytochrome staining of leukocytes in urine sediment. Assessment of inflammatory state.

    abstract::Urinary sediments with significant pyuria were supravitally stained to assess the inflammatory state. Clinic patients showed a significant correlation between acute urinary infection, inflammation, and the predominance of live polymorphonuclear leukocytes. Post-transurethral prostatic resection patients demonstrated t...

    journal_title:Urology

    pub_type: 杂志文章

    doi:10.1016/0090-4295(77)90308-9

    authors: Guthinger WP,Pranikoff K,Cockett AT

    更新日期:1977-06-01 00:00:00

  • Laparoscopic nephrectomy for renal neoplasms.

    abstract::Laparoscopic nephrectomy has been shown to be an effective minimally invasive technique for treating benign renal disease requiring surgical excision. However, its application to approach renal malignancy has been limited. Herein, we report on 8 patients with renal tumor who underwent a laparoscopic nephrectomy. All k...

    journal_title:Urology

    pub_type: 杂志文章

    doi:10.1016/0090-4295(93)90289-m

    authors: Kavoussi LR,Kerbl K,Capelouto CC,McDougall EM,Clayman RV

    更新日期:1993-11-01 00:00:00

  • Vesicosalpingovaginal fistula.

    abstract::The first reported case of a vesicovaginal fistula in which the fallopian tube serves as a conduit between the bladder and vagina is presented. Clinical manifestations, including recurrent urinary tract infection and cuff abscess, followed vaginal hysterectomy performed three years perviously. ...

    journal_title:Urology

    pub_type: 杂志文章

    doi:10.1016/0090-4295(76)90053-4

    authors: Turner BI,Ekbladh L,Edson M

    更新日期:1976-07-01 00:00:00

  • Renal vein ligation in absence of vena caval obstruction.

    abstract::This is a report of a patient whose left renal vein was ligated in the course of a right nephrectomy for a large Wilms tumor, in the presence of an unobstructed vena cava and without established venous collateral circulation. It would appear that even with sudden obstruction to venous outflow the left kidney can devel...

    journal_title:Urology

    pub_type: 杂志文章

    doi:10.1016/0090-4295(80)90478-1

    authors: Tucci P,Diagonale AM,Visani S,Gentile RL

    更新日期:1980-04-01 00:00:00

  • Growth factors in urologic tissues: detection, characterization, and clinical applications.

    abstract::During the last two decades, enormous strides have been made in understanding cellular and molecular biology. The direction of treatment of many neoplasms and other diseases are starting at the microscopic level. Growth factors are polypeptides that play a part in the development and maintenance of living tissues. We,...

    journal_title:Urology

    pub_type: 杂志文章,评审

    doi:10.1016/0090-4295(92)90400-q

    authors: Mydlo JH,Macchia RJ

    更新日期:1992-12-01 00:00:00

  • PSA levels and the rate of positive surgical margins in radical prostatectomy specimens preceded by androgen blockade in clinical B2 (T2bNxMo) prostate cancer. The Lupron Depot Neoadjuvant Study Group.

    abstract:OBJECTIVES:Neoadjuvant hormonal therapy reduces positive margins in patients undergoing radical prostatectomy. All patients experience a decrease in serum prostate specific antigen (PSA), but not always to a level that is nondetectable. The results of several prospective, randomized trials indicate that the incidence o...

    journal_title:Urology

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1016/s0090-4295(97)00172-6

    authors: McLeod DG,Johnson CF,Klein E,Peabody JO,Coffield S,Soloway M

    更新日期:1997-03-01 00:00:00

  • Use of glyceryl trinitrate patches in patients with ureteral stones: a randomized, double-blind, placebo-controlled study.

    abstract:OBJECTIVES:To report a randomized, double-blind, placebo-controlled trial of glyceryl trinitrate (GTN) patches. The primary outcome measure was stone passage at 6 weeks. GTN is a potent smooth muscle relaxant that may offer benefit by both reducing pain and facilitating ureteral stone passage. METHODS:Fifty consecutiv...

    journal_title:Urology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0090-4295(01)01323-1

    authors: Hussain Z,Inman RD,Elves AW,Shipstone DP,Ghiblawi S,Coppinger SW

    更新日期:2001-10-01 00:00:00

  • A 12-year experience with enterovesical fistulas.

    abstract:OBJECTIVES:To review our experience with enterovesical fistulas in order to determine the most accurate diagnostic studies and most effective method of treatment. METHODS:A retrospective record review of 76 patients who were diagnosed and treated for enterovesical fistulas over a 12-year period was performed. Data col...

    journal_title:Urology

    pub_type: 临床试验,杂志文章

    doi:10.1016/s0090-4295(94)80200-9

    authors: McBeath RB,Schiff M Jr,Allen V,Bottaccini MR,Miller JI,Ehreth JT

    更新日期:1994-11-01 00:00:00

  • When the sling is too proximal: a specific mechanism of persistent stress incontinence after pubovaginal sling placement.

    abstract:OBJECTIVES:To review a series of patients with persistent stress urinary incontinence (SUI) after pubovaginal sling (PVS) placement because of an excessively proximal position of the graft on the bladder neck. METHODS:Four women, who had previously undergone PVS placement for SUI, presented for evaluation of persisten...

    journal_title:Urology

    pub_type: 杂志文章,评审

    doi:10.1016/j.urology.2004.03.038

    authors: Poon C,Zimmern P

    更新日期:2004-08-01 00:00:00

  • Results of a national population-based study of outcomes of surgery for renal tumors associated with inferior vena cava thrombus.

    abstract:OBJECTIVE:To determine whether surgeon or hospital volume effects in-hospital mortality or complications of radical nephrectomy with concomitant removal of inferior vena cava (IVC) thrombus, we examine a national population-based cohort. Radical nephrectomy with removal of IVC thrombus is a complex urologic operation, ...

    journal_title:Urology

    pub_type: 杂志文章

    doi:10.1016/j.urology.2013.04.054

    authors: Toren P,Abouassaly R,Timilshina N,Kulkarni G,Alibhai S,Finelli A

    更新日期:2013-09-01 00:00:00

  • Secondary tumors of ureter.

    abstract::Carcinoma metastatic to the ureter, representing hematogenous or lymphatic spread from a distant primary neoplasm, was diagnosed in 39 patients. Although the lesions are uncommon and usually represent late manifestations of malignant disease, earlier recognition and relief of urinary tract obstruction may allow for im...

    journal_title:Urology

    pub_type: 杂志文章

    doi:10.1016/0090-4295(79)90075-x

    authors: Babaian RJ,Johnson DE,Ayala AG,Sie ET

    更新日期:1979-10-01 00:00:00

  • Enuresis as protective factor in vesicoureteral reflux.

    abstract::In 83 patients with non-neurologic, nonoperated vesicoureteral reflux the relation between enuresis and nephropathy was analyzed. The material showed that in spite of identical age, sex distribution, previous history of recurrent urinary tract infections, and the number of refluxing units, patients with enuresis showe...

    journal_title:Urology

    pub_type: 杂志文章

    doi:10.1016/0090-4295(85)90156-6

    authors: Nielsen JB,Nørgaard JP,Djurhuus JC

    更新日期:1985-11-01 00:00:00

  • Mass circumcision with a novel plastic clamp technique.

    abstract:OBJECTIVE:To evaluate the safety and efficacy of mass circumcision performed using a plastic clamp. METHODS:A total of 2013 males, including infants, children, adolescents, and adults were circumcised during a 7-day period by using a plastic clamp technique. Complications were analyzed retrospectively in regard to 4 d...

    journal_title:Urology

    pub_type: 杂志文章

    doi:10.1016/j.urology.2010.12.018

    authors: Senel FM,Demirelli M,Pekcan H

    更新日期:2011-07-01 00:00:00

  • Sensitivity to Change of Subdomain Question 6 of the Urogenital Distress Inventory Short Form After Sling Removal for Pain.

    abstract:OBJECTIVE:To determine the sensitivity to change of question 6 (Q6) of the modified short form version of the Urogenital Distress Inventory (UDI-6) before and after synthetic sling removal (SSR). METHODS:Following IRB approval, a prospectively maintained database of mid-urethral sling (MUS) complications identified wo...

    journal_title:Urology

    pub_type: 杂志文章

    doi:10.1016/j.urology.2020.10.029

    authors: Wang CN,Christie AL,Zimmern PE

    更新日期:2021-01-01 00:00:00

  • Natural history and epidemiology of benign prostatic hyperplasia: relationship among urologic measures.

    abstract::Numerically weak correlations can stem from research studies for numerous reasons, some of which have little to do with lack of true physiologic relationships. Previous investigators have reported relatively weak correlations among urologic measures, mostly based on patients referred to urologic clinics. Such samples ...

    journal_title:Urology

    pub_type: 杂志文章,评审

    doi:10.1016/s0090-4295(98)00049-1

    authors: Girman CJ

    更新日期:1998-04-01 00:00:00

  • Nocturia in interstitial cystitis/painful bladder syndrome.

    abstract:OBJECTIVES:To explore the roles of pain and urgency in the nocturia of patients with interstitial cystitis/painful bladder syndrome (IC/PBS). METHODS:In a longitudinal study of incident IC/PBS cases, we assessed the associations of the presence and severity of nocturia with the presence and severity of pain and urgenc...

    journal_title:Urology

    pub_type: 杂志文章

    doi:10.1016/j.urology.2011.02.012

    authors: Warren JW,Horne L,Diggs C,Greenberg P,Langenberg PW

    更新日期:2011-06-01 00:00:00

  • Testicular seminoma originating in an undescended testis in a renal allograft recipient.

    abstract::Immunosuppressed transplant recipients are at significantly increased risk for developing neoplasms than are nonimmunosuppressed individuals. However, only six cases of pure testicular seminoma following renal transplantation have been reported in the English literature. This case report represents the first descripti...

    journal_title:Urology

    pub_type: 杂志文章,评审

    doi:10.1016/s0090-4295(96)00104-5

    authors: Modlin CS,Flechner SM,Penn I

    更新日期:1996-07-01 00:00:00

  • The effects of transrectal radiofrequency hyperthermia on patients with chronic prostatitis and the changes of MDA, NO, SOD, and Zn levels in pretreatment and posttreatment.

    abstract:OBJECTIVE:To assess the effect of transrectal radiofrequency hyperthermia (TRFH) in 159 patients with chronic prostatitis (CP) and explore the changes of reactive oxygen species in CP patients pretreatment and posttreatment. METHODS:Patients diagnosed with CP were randomized to 6 weeks of tamsulosin plus clarithromyci...

    journal_title:Urology

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.urology.2011.08.046

    authors: Gao M,Ding H,Zhong G,Lu J,Wang H,Li Q,Wang Z

    更新日期:2012-02-01 00:00:00

  • Renal venography in diagnosis of infiltrating transitional cell carcinoma of renal pelvis.

    abstract::Urologic evaluation of a ninety-two-year-old man with hematuria suggested lower segmental renal infarction on selective renal angiogram. Nonvisualization of the lower segmental venous tributaries and capillaries on renal venogram was consistent with the operative findings of microscopic infiltrating transitional cell ...

    journal_title:Urology

    pub_type: 杂志文章

    doi:10.1016/0090-4295(81)90429-5

    authors: Bernath AS,Addonizio JC,Kinkhabwala M,Thelmo W

    更新日期:1981-08-01 00:00:00

  • Ureteral replacement using porcine small intestine submucosa in a porcine model.

    abstract:OBJECTIVES:To investigate an alternative technique using an onlay patch of porcine small intestine submucosa (SIS) allograft to bridge a ureteral defect. For ureteral strictures that fail endourologic management, few options are available for minimally invasive repair or reconstruction. Although laparoscopic interposit...

    journal_title:Urology

    pub_type: 杂志文章

    doi:10.1016/s0090-4295(02)01890-3

    authors: Smith TG 3rd,Gettman M,Lindberg G,Napper C,Pearle MS,Cadeddu JA

    更新日期:2002-11-01 00:00:00

  • Women in Leadership in Urology: The Case for Increasing Diversity and Equity.

    abstract::There is a persistent male gender predominance in urology, especially with respect to female representation in leadership. We review the current status of women in urology leadership, discuss challenges women face in leadership positions, present the case for adopting inclusive practices that increase diversity and ge...

    journal_title:Urology

    pub_type: 杂志文章

    doi:10.1016/j.urology.2020.07.079

    authors: Chyu J,Peters CE,Nicholson TM,Dai JC,Taylor J,Garg T,Smith AB,Porten SP,Greene K,Browning N,Harris E,Sutherland SE,Psutka SP

    更新日期:2020-09-20 00:00:00

  • Nondismembered ureteroplasty for congenital midureteral stenosis: a new application of an old technique.

    abstract:OBJECTIVES:To share our experience with nondismembered ureteroplasty (NDU), a novel application of an old technique in congenital midureteral stenosis (CMS). METHODS:A 35-year-old man was diagnosed as a case of CMS, a rare benign condition on the basis of extensive evaluation, including ultrasonography, intravenous ur...

    journal_title:Urology

    pub_type: 杂志文章

    doi:10.1016/j.urology.2010.03.093

    authors: Goel A,Singh D,Sengottayan VK,Sankhwar S

    更新日期:2010-10-01 00:00:00

  • Hemostatic laparoscopic partial nephrectomy: initial experience with the radiofrequency coagulation-assisted technique.

    abstract:OBJECTIVES:The techniques for hemostasis after renal tumor excision have limited the widespread application of laparoscopic partial nephrectomy (LPN). To improve hemostasis and aid visualization, we report our experience with a novel radiofrequency coagulation (RFC) technique for LPN. METHODS:Ten patients underwent RF...

    journal_title:Urology

    pub_type: 临床试验,杂志文章

    doi:10.1016/s0090-4295(01)01086-x

    authors: Gettman MT,Bishoff JT,Su LM,Chan D,Kavoussi LR,Jarrett TW,Cadeddu JA

    更新日期:2001-07-01 00:00:00