Abstract：
AIM:To perform a systematic review and meta-analysis of the effectiveness and complications of BRTO for gastric varices. MATERIALS AND METHODS:A systematic review was performed to identify relevant articles. Inclusion criteria were applied to select studies with at least ten patients with acute bleeding or at-risk gastric varices treated with BRTO. Meta-analysis with random effects model was performed to calculate data for immediate technical success, clinical success, and complications. RESULTS:A total of 1,016 Patients from 24 studies met inclusion criteria. Technical success rate for BRTO was 96.4 % (95 % CI 93.7, 98.3 %; Q = 3,269.26, p < 0.01, I (2) = 99.39 %). Clinical success (defined as no recurrence or rebleed of gastric varices, or complete obliteration of varices on subsequent imaging) rate was 97.3 % (95 % CI 95.2, 98.8 %; Q = 3,105.91, p < 0.01, I (2) = 99.29 %). Major complication rate was 2.6 % (95 % CI 1.1, 4.6 %; Q = 3,348.98, p < 0.01, I (2) = 99.34 %). Esophageal variceal recurrence rate was 33.3 % (95 % CI 24.6, 42.6 %; Q = 7,291.75, p < 0.01, I (2) = 99.74 %). CONCLUSION:BRTO is safe and efficacious for gastric varices, and current best evidence suggests that BRTO could be considered as therapy for patients with gastric varices.
journal_name
Dig Dis Scijournal_title
Digestive diseases and sciencesauthors
Park JK,Saab S,Kee ST,Busuttil RW,Kim HJ,Durazo F,Cho SK,Lee EWdoi
10.1007/s10620-014-3485-8subject
Has Abstractpub_date
2015-06-01 00:00:00pages
1543-53issue
6eissn
0163-2116issn
1573-2568journal_volume
60pub_type
杂志文章,meta分析,评审abstract：BACKGROUND:Intestinal failure is the most critical complication of Crohn's disease. Intestinal failure requires home parenteral nutrition, which worsens the quality of life of the patients and sometimes causes life-threatening complications. AIMS:The purpose of this study was to investigate the incidence and risk fact...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-019-05553-2
更新日期：2019-08-01 00:00:00
abstract：:To investigate a potential new treatment for gastric Helicobacter pylori infection, we have examined the use of the natural antibiotic lactoferrin, found in bovine milk, for activity against Helicobacter species both in vitro and in vivo. Lactoferrin was bacteriostatic to H. pylori when cultured at concentrations > or...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1023/a:1026675916421
更新日期：1998-12-01 00:00:00
abstract：:Previous studies have shown that duodenal motility patterns differ in preterm and term infants, but antral motor activities were not compared. Using a validated, low-compliance, continuous-perfusion, neonatal manometric system, antral and duodenal motility was studied in 19 preterm and nine term infants. Antral motili...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01308336
更新日期：1992-01-01 00:00:00
abstract：:Turmeric is widely used in Indian cuisine. The main constituents of turmeric are curcumin and its analogues, which are well-known antioxidant compounds. In the present study, we hypothesized that turmeric in curry might increase bowel motility and activate hydrogen-producing bacterial flora in the colon, thereby incre...
journal_title：Digestive diseases and sciences
pub_type： 临床试验,杂志文章
doi：10.1007/s10620-008-0550-1
更新日期：2009-08-01 00:00:00
abstract：:As chronic liver disease progresses, an imbalance occurs between synthesis and breakdown of extracellular matrix (ECM). Matrix metalloproteinases (MMPs) are involved in degrading ECM while tissue inhibitors of metalloproteinases (TIMPs) prevent their fibrolytic action. We determined if plasma levels of MMP-2, TIMP-1 a...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1023/a:1026630129025
更新日期：1999-03-01 00:00:00
abstract：:The ascitic fluid concentrations of cholesterol and fibronectin and the serum-ascites albumin difference were compared with two conventional tests of ascitic fluid, total protein and LDH, in their diagnostic ability for detection of malignancy in ascitic samples from 69 patients with ascites: 54 with ascites due to li...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01550972
更新日期：1988-07-01 00:00:00
abstract：BACKGROUND:Accumulating evidence suggests that Foxp3+ regulatory T (Treg) cells act as inhibitory mediators of inflammation; however, the in vivo mechanism underlying this protection remains elusive in liver diseases. AIMS:To clarify the in vivo role of Foxp3+ Treg cells in liver fibrosis, we used the DEREG mouse, whi...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-014-3438-2
更新日期：2015-07-01 00:00:00
abstract：:Transient delayed gastric emptying is reported as a frequent complication following pancreas-preserving pancreaticoduodenectomy (PPW). We placed serosal electrodes on the stomach of a patient undergoing PPW. Myoelectric recordings were obtained postoperatively and correlated with simultaneous radionuclide liquid gastr...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01536411
更新日期：1990-10-01 00:00:00
abstract：:The use of total parenteral nutrition and enteral nutrition in inflammatory bowel disease has become commonplace. Except for well-documented improvements in nutritional parameters, the efficacy of these treatments for primary therapy or for complications remains largely unproven. ...
journal_title：Digestive diseases and sciences
pub_type： 临床试验,杂志文章,评审
doi：10.1007/BF01312471
更新日期：1987-12-01 00:00:00
abstract：:The purpose of this study was to determine the effects of altering gastric emptying on postprandial plasma glucose concentration after a physiologic meal in patients with type II diabetes mellitus (T II DM). Nine T II DM patients underwent a double-blind, randomized, three-way crossover study, receiving erythromycin 2...
journal_title：Digestive diseases and sciences
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1023/a:1022528414264
更新日期：2003-03-01 00:00:00
abstract：:We have developed a breath test to measure solid gastric emptying using a standardized scrambled egg test meal (250 kcal) labeled with [14C]octanoic acid or [13C]octanoic acid. In vitro incubation studies showed that octanoic acid is a reliable marker of the solid phase. The breath test was validated in 36 subjects by...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF02300385
更新日期：1994-12-01 00:00:00
abstract：:The present study aimed to clarify the endoscopic ultrasonography (EUS) features of nonneoplastic (cholesterol polyps and adenomyomatosis) and neoplastic (adenoma and adenocarcinoma) gallbladder polyps and to evaluate the effectiveness and limitation of EUS in the differential diagnosis of these lesions. We retrospect...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-006-3146-7
更新日期：2006-02-01 00:00:00
abstract：:To study the clinicopathologic features of hepatitis C viremic patients negative for hepatitis C antibodies (anti-HCV) by current second-generation assay, we categorized 139 consecutive histologically verified patients with chronic non-A, non-B hepatitis into three groups: 121 (87%) were positive for second-generation...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF02208599
更新日期：1996-01-01 00:00:00
abstract：:Despite progress in therapeutic approaches for the elimination of hepatitis C, chronic hepatitis C virus infection remains an important cause of liver disease. Therapeutic intervention with the currently available interferon-based treatment regimens is quite successful, but treatment is difficult to tolerate and is co...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章,评审
doi：10.1007/s10620-006-9484-7
更新日期：2007-04-01 00:00:00
abstract：:Clinical features and liver biopsy findings were studied in six patients with nonalcoholic steatohepatitis associated with hyalin. A comparative study was made on the ultrastructure of the hyalin in one patient with nonalcoholic steatohepatitis and in one patient with alcoholic hepatitis. The patients, all over 50 yea...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01296754
更新日期：1982-04-01 00:00:00
abstract：:The aim of this study was to assess the efficacy of the combination of endoscopic variceal ligation (EVL) and partial splenic embolization (PSE) compared with EVL alone in cirrhosis patients with thrombocytopenia. In a prospective study, 84 cirrhosis patients with esophageal varices and thrombocytopenia (platelet coun...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10620-006-3137-8
更新日期：2006-02-01 00:00:00
abstract：BACKGROUND:Regular screening of cirrhotic patients for hepatocellular carcinoma (HCC) has been suboptimal, but there is little data regarding specific risk factors for reduced screening. METHODS:From 1996 to 2010, patients with cirrhosis were retrospectively identified from outpatient gastroenterology and primary care...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-011-1836-2
更新日期：2011-11-01 00:00:00
abstract：:To evaluate pancreatic exocrine function in uremia, 25 patients undergoing regular hemodialysis without clinical evidence of pancreatic disease and 25 healthy control subjects were studied by fecal elastase 1 and chymotrypsin. Abdominal ultrasonography and measurement of serum lipase, calcium, phosphate, and parathorm...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1023/a:1026487807555
更新日期：2000-11-01 00:00:00
abstract：:A comparative study of three different high-dose regimens of interferon-alpha-2b (IFN) was conducted in patients with chronic hepatitis C to determine which was better at obtaining a sustained remission. A total of 126 patients were assigned randomly to one of three groups: group A was given 10 million international u...
journal_title：Digestive diseases and sciences
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1007/BF01316789
更新日期：1993-04-01 00:00:00
abstract：:Cholestasis, which affects phospholipid trafficking, therefore would be expected to alter canalicular membrane phospholipid composition and fluidity, as well as fatty acid composition of membrane phospholipid. These alterations may affect transcytotic vesicle fusion and would be expected to cause variety of cholestati...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1023/a:1026639716440
更新日期：1999-08-01 00:00:00
abstract：BACKGROUND:Both colorectal neoplasms and atherosclerosis can be induced by common visceral fat accumulation. However, the association between these diseases at the advanced stage, colorectal cancer and cardiovascular/cerebrovascular diseases, has not been elucidated. AIMS:This study aimed to investigate the associatio...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-016-4041-5
更新日期：2016-06-01 00:00:00
abstract：:To date few therapies have been shown to reliably prevent the evolution of Crohn's disease (CD). The traditional Chinese medicine, Tripterygium wilfordii Hook F (TWHF), has both immunomodulatory and anti-inflammatory activities. Our aim was to investigate the potential efficacy of T2, the major constituent of extracts...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-007-9747-y
更新日期：2007-08-01 00:00:00
abstract：BACKGROUND:Esophageal stricture is one of the serious adverse events following endoscopic submucosal dissection (ESD). However, optimum preventive techniques are still lacking. AIMS:Our primary objective was to evaluate the incidence of post-ESD esophageal stricture with the application of carboxymethyl cellulose (CMC...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-016-4034-4
更新日期：2016-06-01 00:00:00
abstract：:The current cost of endoscopically screening patients with gastroesophageal reflux disease (GERD) and Barrett's esophagus (BE) is considerable. A nonendoscopic device that allows for screening of these patients would offer significant cost savings. This pilot study evaluates the utility of cytologically diagnosing BE ...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1023/a:1012771328187
更新日期：2001-12-01 00:00:00
abstract：:Forty-nine Japanese patients were enrolled in a randomized, placebo-controlled, double-blind trial of alpha-interferon for chronic non-A, non-B hepatitis: 24 patients received 3 million units of recombinant human alpha alpha-interferon (alpha-2a) thrice weekly for eight weeks, and 25 patients received placebo in a sim...
journal_title：Digestive diseases and sciences
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/BF01307512
更新日期：1991-09-01 00:00:00
abstract：:It is unknown whether demography, gallbladder function, or the radiographic appearance of gallstones predispose them to cause symptoms. We investigated these features in a consecutive series of 260 patients with newly diagnosed, uncomplicated gallstone disease, of whom 146 had experienced biliary pain and 114 were asy...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF02087779
更新日期：1994-08-01 00:00:00
abstract：:Sumatriptan, a 5-HT1-receptor agonist has been shown to delay gastric emptying of liquids and solids in humans. However, no data are available of the effect of sumatriptan on gastric adaptation after distension with liquids and on symptoms induced by gastric distension. In 23 normal subjects and 30 dyspeptic patients ...
journal_title：Digestive diseases and sciences
pub_type： 临床试验,杂志文章
doi：10.1023/a:1020588832411
更新日期：2002-11-01 00:00:00
abstract：BACKGROUND:Data regarding early atherosclerosis and inflammatory bowel disease are limited and conflicting results are present. AIMS:The purpose of this study was to evaluate serological and sonographical evidence of subclinical vascular involvement in patients with inflammatory bowel disease. METHODS:Thirty-nine pat...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-012-2148-x
更新日期：2012-08-01 00:00:00
abstract：:To examine the relationship between peptic ulcer and gastric cancer, we investigated 2529 patients with peptic ulcer diagnosed from 1963 to 1975. During the follow-up period of 9-23 years, we found 38 in whom gastric cancer developed or who died of gastric cancer. Included were nine in whom gastric cancer was detected...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01540181
更新日期：1990-06-01 00:00:00
abstract：BACKGROUND AND AIM:Postoperative infection is not uncommon after hepatectomy. This study assessed the effectiveness of preoperative antibiotic prophylaxis in elective hepatectomy in a randomized clinical trial setting. METHODS:A total of 120 patients who were scheduled to undergo elective hepatectomy were equally rand...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-015-4008-y
更新日期：2016-06-01 00:00:00
