Abstract：
:Self-stimulation (SS) of both the medial prefrontal cortex (MPFC) and the dorsolateral hippocampus (HPC) is known to develop slowly, over a period of days. In both cases, the acquisition of bar-pressing can be markedly hastened by delivery of noncontingent electrical stimulation for several days prior to SS training. The similarity of these effects suggests that there might be a common substrate mediating the acquisition process. However, in the present experiment, pre-training noncontingent electrical stimulation of the MPFC had no effect on how rapidly rats acquired the bar-pressing response for HPC stimulation, or vice versa. A further dissociation of the elements governing the acquisition process for these two SS sites was suggested by the observation that pre-training noncontingent stimulation of the entorhinal cortex facilitated the speed of acquisition of SS of the HPC but not of the MPFC. It seems that the HPC and entorhinal cortex can be excluded from the subset of neural structures which are known to influence the acquisition process governing MPFC SS. These and other data suggest that the development of SS of the MPFC and HPC can be regarded, at least in part, as involving a process rooted in distinct substrates.
journal_name
Physiol Behavjournal_title
Physiology & behaviorauthors
Robertson A,Laferrière A,Milner PMdoi
10.1016/0031-9384(86)90198-8subject
Has Abstractpub_date
1986-01-01 00:00:00pages
409-18issue
3eissn
0031-9384issn
1873-507Xpii
0031-9384(86)90198-8journal_volume
37pub_type
杂志文章abstract：:Individual differences in aggressive behaviour have been linked to variability in central serotonergic activity, both in humans and animals. A previous experiment in mice, selectively bred for high or low levels of aggression, showed an up-regulation of postsynaptic serotonin-1A (5-HT(1A)) receptors, both in receptor ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(01)00565-0
更新日期：2001-09-01 00:00:00
abstract：:Guinea pig pups vocalized more and were more active during a 60-min period of isolation in a novel environment when injected SC with 50 micrograms of the corticotropin-releasing factor (CRF) antagonist, [D-Phe]CRF12-41, than when injected with saline vehicle only. More pups exhibited eye closing and extensive piloerec...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(96)00091-1
更新日期：1996-09-01 00:00:00
abstract：:Two psychophysical methods were used to investigate the capacity of humans to identify the constituents of odor mixtures consisting of up to six components. With one method subjects were required to identify all the components present in each stimulus; with the other, a selective attention procedure was used where sub...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(92)90458-e
更新日期：1992-12-01 00:00:00
abstract：:Olfactory bulbectomy (OBX) in rats produces behavioral, physiological, and neurochemical changes that resemble symptoms of depression in humans. The procedure thus serves as a rodent model of affective disorder. Many of the behavioral effects of OBX resemble psychomotor agitation. The possible role of dysregulation of...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2004.01.003
更新日期：2004-03-01 00:00:00
abstract：:Mixtures of compounds can often be tasted even when all of their components are too weak to be tasted separately. Such mixtures are said to be integrative. Integration was demonstrated by mixing compounds in concentrations proportional to their separate detection thresholds and then measuring the detection threshold o...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(97)00270-9
更新日期：1997-11-01 00:00:00
abstract：:Female mate choice is often investigated in terms of reproductive success in order to understand how male characteristics contribute to sexual attractiveness. Previous studies have found that females rats prefer mating with their first encounter rather than males visited subsequently, suggesting that the rewarding val...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2017.10.031
更新日期：2018-02-01 00:00:00
abstract：:The effects on rodent anxiety of kindling in the medial or basolateral amygdaloid nuclei in each hemisphere were examined. Anxiety was measured using the hole board and elevated plus maze tests. The animals were kindled in medial or basolateral amygdalas, of either the left or right hemisphere. Controls had electrodes...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(94)90002-7
更新日期：1994-01-01 00:00:00
abstract：PURPOSE:Oxidative and inflammatory processes play a major role in stress-induced neural atrophy. There is a wide body of literature linking oxidative and inflammatory stress with reductions in neurotrophic factors, stress resilience, and cognitive function. Based on their antioxidant and anti-inflammatory capacity, we ...
journal_title：Physiology & behavior
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.physbeh.2019.112650
更新日期：2019-11-01 00:00:00
abstract：:The odor of blood may have both aversive and attractive properties for mammals, depending on the species of the odor donor and the species perceiving the odor. To better understand the informational content of blood odor for a prey species we assessed behavioral responses of male CD-1 mice (n=60) to the odor of blood ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2017.12.006
更新日期：2018-02-01 00:00:00
abstract：:Acute infections lead to alterations in behavior, collectively known as sickness behavior, which includes reduction in locomotion, food ingestion, sexual and social behavior, environmental exploration, and sleep profile. Although generally seen as undesired, sickness behavior represents a conserved strategy for animal...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2008.10.018
更新日期：2009-02-16 00:00:00
abstract：:Previously, a hormone-simulated pregnancy (HSP), and the subsequent 'postpartum' withdrawal in estradiol has been shown to precipitate depressive-like behaviours in the forced swim test in female rats. In this study, we used the HSP and 'postpartum' withdrawal to investigate the impact on sucrose consumption, a model ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2009.02.020
更新日期：2009-05-25 00:00:00
abstract：:Sedentary, adult rats of both sexes fed Purina chow and a 32% sucrose solution overate, gained excess weight and had higher Lee Indexes of obesity than control animals fed only Purina chow. The magnitude of these effects was similar in the males and females. Animals of both sexes fed the sucrose diet showed a slower r...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(82)90012-9
更新日期：1982-08-01 00:00:00
abstract：:Following training with distinctively flavored solutions which differ in calories and thus in their postingestive effects, rats demonstrate flavor-postingestive consequence learning by preferentially consuming one of the flavors in two-bottle tests (both flavors presented in nutrient-identical solutions). The directio...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(97)00345-4
更新日期：1997-12-01 00:00:00
abstract：:Adult male and female rats were housed in a sedentary condition or given free access to a running wheel for 50 days. Running wheel activity of female rats was higher than that of males throughout the experiment. Food intake, of both male and female rats that could take exercise increased, and the rate of increase of f...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(82)90211-6
更新日期：1982-05-01 00:00:00
abstract：:The present report explored firstly how palatability modified the effects of energy density (ED) on short-term food intake and changes in rated appetite within a single test meal, and secondly how repeated consumption altered these relationships. Experiment 1 contrasted disguised high (HED) and low (LED) versions of a...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2005.08.019
更新日期：2005-11-15 00:00:00
abstract：:A versatile and easy to use program is described for monitoring and recording behavior durations on IBM-compatible microcomputers. The program also records frequencies and provides latency information. Among its more prominent attributes are its ability to accommodate a broad range of behavioral assays and the facilit...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(90)90158-z
更新日期：1990-02-01 00:00:00
abstract：:Resting heart rate (HR) and HR responses of fetal and neonatal rats are described before and after intraoral infusion of isotonic saline or lemon solution. Stable measurements of resting HR were obtained for fetuses over the last three days of gestation (E19, E20, E21) and pups on the day of birth (P0) and four subseq...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(91)90496-b
更新日期：1991-07-01 00:00:00
abstract：:The effects of fluoxetine on food intake, body weight, and mood of obese individuals was examined in a 16-week inpatient/outpatient study. Six male and eight female obese volunteers began the study (four male and five females completed all phases of the study). They lived in a residential laboratory during three one-w...
journal_title：Physiology & behavior
pub_type： 临床试验,杂志文章
doi：10.1016/s0031-9384(99)00020-7
更新日期：1999-07-01 00:00:00
abstract：:A novel model to evaluate erectile, ejaculatory, and sexual behavior patterns in conscious mouse is presented. Corpus spongiosum of the penis (CSP) pressure was recorded by using telemetry and was correlated with erectile activity (penile elongations, cups, flips) during reflex induction and spontaneous erections in f...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2007.04.016
更新日期：2007-08-15 00:00:00
abstract：:Dysfunction in the circadian system has been linked to emotion regulation and mood disorders with genetic variation in clock genes as likely contributors. Here, we focused on endophenotypes of affective processing and investigated in two independent samples of healthy individuals (n1=99, n2=108) whether genotypes of a...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2020.112831
更新日期：2020-05-15 00:00:00
abstract：:Bombesin has been shown to decrease food intake and increase the duration of slow wave sleep, as well as to increase blood glucose and glucagon. A suspected mechanism of bombesin's anorexigenic and hypnogenic action could be via its possible effect on the enhancement of metabolism itself. Therefore, the effect of bomb...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(91)90262-m
更新日期：1991-03-01 00:00:00
abstract：:Female hamsters (Mesocricetus auratus) exposed to a short photoperiod for 8 weeks were ovariectomized, as were hamsters that were maintained in a long photoperiod. We then tested the effect of photoperiod on the ability of progesterone (P) to reduce aggression, as well as on the effects of estrogen (E), alone and with...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(92)90307-n
更新日期：1992-06-01 00:00:00
abstract：:Toxins and nutrients interact and define herbivores' experiences with toxic plants. However, there are still open questions about the mechanisms by which nutrient-toxin interactions affect experience and as a consequence foraging decisions by consumers. This study provides a deeper insight into such mechanisms by usin...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2016.09.009
更新日期：2016-12-01 00:00:00
abstract：:The conditioned taste aversion (CTA) is routinely used to assess the aversive consequences of anorexic agents, including potential pharmacological therapies for obesity. In a typical CTA paradigm, rats briefly sampling a novel tastant (e.g., saccharin) are acutely administered with toxin (e.g., lithium chloride, LiCl)...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(03)00189-6
更新日期：2003-09-01 00:00:00
abstract：:This report describes a standard procedure for studying the disordered eating behavior of bulimic patients in a laboratory setting. Test meals were given to eight normal weight women with bulimia under four different conditions on non-consecutive days. On day 1 they were asked to consume as much as they "would normall...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(86)90426-9
更新日期：1986-10-01 00:00:00
abstract：:The effect of single and chronic methamphetamine (MAP) administration on ischemia-induced hyperactivity was investigated and the mechanism of ischemia-induced hyperactivity was discussed. Ischemia-induced hyperactivity was recognized 3 h after ischemia. However, ischemia-induced hyperactivity at 1 day after ischemia w...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(01)00549-2
更新日期：2001-09-01 00:00:00
abstract：:The androgen receptor (AR) is a widely distributed molecule indicating the spread actions of its ligand steroid, and plays an important role underlying male sexual behavior. Nevertheless, the influence of steroid hormones and their receptors on cerebellar neurons, as foundation of sexual behavior, is largely unknown. ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2016.01.027
更新日期：2016-03-15 00:00:00
abstract：:Recent studies suggest that the decreased drinking response to hypertonic saline produced by bilateral subdiaphragmatic vagotomy (VGX) is a function of the route of saline administration and the length of postoperative recovery. We determined the effects of VGX on drinking during the two hours after intraperitoneal an...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(82)90086-5
更新日期：1982-02-01 00:00:00
abstract：:Several studies have demonstrated that nicotine (NIC) exhibits antidepressant-like effects. In addition, it has been suggested that sexual hormones participate in the antidepressant actions of antidepressives. The present study was designed to analyze the effect of orchiectomy and the supplementation of testosterone p...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2010.07.011
更新日期：2010-11-02 00:00:00
abstract：:One group of male rats was reared continuously in small, stable colonies of three animals each during a ten-week period beginning when they were 46 days old. A second group of animals was also reared in small groups of three animals each but membership within these colonies was randomly changed at weekly intervals. Th...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(84)90373-1
更新日期：1984-10-01 00:00:00
