[Optimization of irradiation time in the treatment of malignant melanoma of the choroid with beta applicators (106Ru/106Rh)].

Abstract:

:Brachytherapy with 106Ru/106Rh necessitates protracted irradiation because the applicators have to be sutured to the sclera. Protracted radiotherapy causes more intensive damage in tumor cells with increased metabolism and a higher mitosis rate than in normal tissue. Beta irradiation of rabbit eyes with 0.258-0.231 Gy/min produced more extensive exudative reactions and morphological damage of the retina than a lower dosage rate with 0.035-0.026 Gy/min and the same total dose of 650 Gy. For the study reported here 75 patients suffering from choroidal melanoma and irradiated with 106Ru/106Rh plaques between 1967 and 1977 were evaluated. They developed more exudative and hemorrhagic side effects after a short period of irradiation (1-6 days) than after a longer one (7-14 days). Spontaneous recovery of the radiation-induced retinal detachment was seen in all cases. Complete tumor regression with development of a flat scar was achieved with almost equal success with both short-term and protracted irradiation. To minimize radiogenic side effects the duration of irradiation recommended hitherto, i.e., 7-14 days, should be adhered to when treating malignant melanomas of the choroid with beta-ray applicators.

journal_name

Klin Monbl Augenheilkd

authors

Lommatzsch PK,Weise B,Ballin R

doi

10.1055/s-2008-1050770

subject

Has Abstract

pub_date

1986-08-01 00:00:00

pages

133-40

issue

2

eissn

0023-2165

issn

1439-3999

journal_volume

189

pub_type

杂志文章
  • [Trepanation with scleral flap (Elliot-Fronimopoulos) in acute narrow-angle glaucoma (author's transl)].

    abstract::120 eyes with acute closed angle glaucoma were operated by goniotrepanation (Elliot-Fronimopoulos). The follow-up controls showed excellent results. Especially the quick restoration of the anterior chamber and the increase in its depth must be emphasized. There are very rare complications and the resulting eye pressur...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Doden W,Hosch W

    更新日期:1976-12-01 00:00:00

  • [A contribution of the course of vitreous haemorrhage (author's transl)].

    abstract::After some basic remarks about the physiological adhesions of the vitreous body to its surrounding structures in the anterior part of the eye (lens, ciliary body, pars plana) and the posterior part of the eye (macular, optic disc) the general history of bleeding in the vitreous body and the different possibilities of ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Plange H,Speiser P

    更新日期:1976-10-01 00:00:00

  • [Visualization of Retinal Neovascularization with Optical Coherence Tomography Angiography in Comparison with Fluorescein Angiography].

    abstract:OBJECTIVE:Comparison of retinal neovascularizations of the disc (NVD) and elsewhere (NVE) in optical coherence tomography angiography (OCTA) and fluorescein angiography (FA) in patients with proliferative diabetic retinopathy. MATERIALS AND METHODS:15 consecutive patients were included in this study. All patients rece...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/a-0983-2271

    authors: Enders C,Baeurle F,Lang GE,Dreyhaupt J,Trick S,Kilani A,Lang GK,Werner JU

    更新日期:2019-11-01 00:00:00

  • [Hereditary Optic Neuropathies].

    abstract::Hereditary optic nerve disorders are rare. For ophthalmologists, Leber's hereditary optic neuropathy (LHON) and autosomal dominant optic atrophy (ADOA) are of particular relevance. LHON and ADOA are diseases of the retinal ganglion cells and are caused by mitchochondrial dysfunction. LHON is based on mutations of the ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章,评审

    doi:10.1055/a-0583-6290

    authors: Rüther K

    更新日期:2018-06-01 00:00:00

  • [Individual postoperative refraction after cataract surgery -- a comparison of optical and acoustical biometry].

    abstract:BACKGROUND:Optical biometry with the IOL-Master is an innovative technique that claims to improve the refractive results of cataract surgery compared to acoustical biometry. METHODS:In 140 consecutive non-selected eyes prior to cataract surgery firstly an optical biometry (IOL-Master, Zeiss, V.2.02) and secondly an ul...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2004-813385

    authors: Kutschan A,Wiegand W

    更新日期:2004-09-01 00:00:00

  • [Further observations on the application of the campimetric method for measuring individually tolerated intraocular pressure in glaucoma].

    abstract::The results of campimetric investigations performed in 127 eyes (83 patients) are presented. The vertical diameter of the blind spot and intraocular pressure were measured several times before and after oral intake of a dose of glycerol combined with ascorbic acid. The tonometric value obtained when the blind spot is ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1055032

    authors: Wodowosow AM,Boriskina MG,Kotjeljnikowa OF

    更新日期:1982-02-01 00:00:00

  • [Use of high-frequency ultrasound for foreign body imaging in chronic conjunctivitis due to microtrauma].

    abstract::Conjunctivitis is a frequent disease mostly caused by infections. In the case of a single-sided manifestation and additional resistance to anti-infective therapy a widespread differential diagnosis has to be considered. The case report of a 41-year-old patient suffering from unilateral persistent conjunctivitis is pre...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1027457

    authors: Jürgens C,Geitz W,Tost FH

    更新日期:2008-07-01 00:00:00

  • [Are cross-eyed persons worse drivers? The effect of stereoscopic disparity on driving skills].

    abstract:BACKGROUND:The motorist obtains about 90% of the information required to drive a vehicle from the sense of vision. In road traffic, various situations with respect to size, distance, and position have to be evaluated at different speeds. Does depth perception based on disparity play an essential role in these situation...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2000-10343

    authors: Bauer A,Kolling G,Dietz K,Zrenner E,Schiefer U

    更新日期:2000-09-01 00:00:00

  • [Necessary pressure in the ophthalmic artery].

    abstract::As a result of an acute pathologic event ophthalmic arterial pressure may fall below a level necessary to supply sufficient blood to the eye and optic nerve, and thus to preserve full visual function. A sudden partial or even total loss of visual function. A sudden partial or even total loss of vision may follow. In s...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1057432

    authors: Stepanik J

    更新日期:1980-02-01 00:00:00

  • [Refraction after cataract surgery with posterior chamber lenses].

    abstract::In an attempt to determine the accuracy of ultrasound biometry, the spherical equivalent of the refraction obtained after ECCE and implantation of a posterior chamber IOL in 1663 patients was compared to the desired refraction determined prior to surgery. Follow up time was 21 months on the average. In only 7.4% of th...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1046055

    authors: Spitznas M,Werdermann D,Ohlhorst D

    更新日期:1991-08-01 00:00:00

  • [Results of Cüpper's "thread fixation" in squinters with inconstant angle (author's transl)].

    abstract::The results of strabismus operations on strabismus patients with variable angles are presented. The so-called "Fadenfixation" (Cüppers) is compared with the usual recess-resect method. Of the 62 cases of strabismus with variable angle which were operated without the "Fixation", only 3 cases were parallel post-operatio...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Behrens-Baumann W,Wölz U

    更新日期:1978-12-01 00:00:00

  • [Better prognosis for amblyopics by means of full prismatic correction after monocular treatment (author's transl)].

    abstract::Binocular training with full prismatic correction after the monocular therapy by occlusion brings a further improvement of the visual acuity as well as shown in a study of 29% (138 cases) of 469 selected cases with binocular problems and 43% (260 cases) of about 600 unselected cases of squint actually in treatment in ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Pestalozzi D,Schwarzenbach A

    更新日期:1979-09-01 00:00:00

  • [Vision Screening in Zurich].

    abstract:BACKGROUND:In the city of Zurich, vision screening is performed by school medical services as part of the legally compulsory preventive medical examinations. We retrospectively evaluated the results of the 2011-2012 school year. PATIENTS AND METHODS:Preventive medical examinations by the school medical services were p...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-0041-111818

    authors: Sturm V,Heckmann J,Wandernoth P,Kunz A,Steffen T,Schmitt Oggier S

    更新日期:2016-04-01 00:00:00

  • [Acute retinal necrosis].

    abstract::Acute retinal necrosis (ARN) is a rare entity caused by Herpes viruses. An immunocompromised background and the complications of ARN mostly lead to a poor visual outcome. Confirmation of the early diagnosis through polymerase chain reaction and antibody detection from aqueous or vitreous taps is recommended to improve...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章,评审

    doi:10.1055/s-2007-963182

    authors: Winterhalter S,Adams O,Althaus Ch,Stammen J,Schöler EM,Joussen AM

    更新日期:2007-07-01 00:00:00

  • [The effects of the xenon arc lamp upon the iris of the pigmented rabbit eye (author's transl)].

    abstract::The ultrastructural alterations of 10 pigmented rabbit irides 15 minutes to 257 days after irradiation with a xenon arc lamp were analysed. Pulse duration was varied while irradiation power was kept constant at 3.24 W. 0.32 J (= 100 ms pulse duration) were delivered to the left eye and 3.2 J (= 1 second pulse duration...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Bernhard K,van der Zypen E,Fankhauser F

    更新日期:1979-06-01 00:00:00

  • [Ocular Manifestation of Mucopolysaccharidosis I-S (Scheie's Syndrome)].

    abstract:BACKGROUND:Bilateral stromal corneal opacifications are a differential diagnostical challenge to identify associated systemic diseases. CASE-REPORT:A 47-year old civil engineer (height 167 cm) with bilateral stromal corneal clouding presented with visual loss for the last 27 years: VA 20/100 OD and 20/50 OS (following...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2002-35688

    authors: Viestenz A,Shin YS,Viestenz A,Naumann GO

    更新日期:2002-10-01 00:00:00

  • Long-term evaluation of anatomic and functional results after complicated retinal detachment treated with pars plana vitrectomy and heavy silicone oil tamponade.

    abstract:BACKGROUND:Heavier than water tamponades offer the possibility to support the inferior part of the fundus after retinal detachment. The aim of this study was to evaluate the anatomic and functional outcome of complicated retinal detachment treated with vitreous surgery and heavy silicone oil (HSO) tamponade. Surgery wa...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-0028-1109685

    authors: Regler R,Sachs HG,Hillenkamp J,Helbig H,Framme C

    更新日期:2009-09-01 00:00:00

  • [Medical Management of Glaucoma].

    abstract::Glaucoma is the leading cause of irreversible blindness in Germany and in the world. Due to the multifactorial genesis of the disease, there are multiple therapeutic approaches for preventing its progression. The goal of the commonly used topical glaucoma medication is to reduce the intraocular pressure and therefore ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/a-1229-1390

    authors: Emrani E

    更新日期:2020-10-01 00:00:00

  • [Bilateral congenital microblepharon with ectropion and microphthalmus (author's transl)].

    abstract::A very rare combination of congenital malformations of the eyelids and eyes in a 6-month-old boy is reported. The main symptoms are a bilateral microblepharon associated with ectropion and bilateral aphakic microphthalmus. The pathogenesis of these changes is discussed. ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1057334

    authors: Klauss V,Mnyalla ND,Dechant W,Riedel K

    更新日期:1981-11-01 00:00:00

  • [Comparative studies of the pressure-lowering effect of timolol and phospholine iodide (author's transl)].

    abstract::A comparative study of the intraocular pressure-lowering effects of timolol and phospholine iodide in cases of aphakic glaucoma was carried out. The authors compared the I.O.P.-lowering effect of these two drugs in 30 eyes (30 patients) with aphakic glaucoma over an eight-month observation period. The following was es...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1057292

    authors: Christakis C,Mangouritsas N

    更新日期:1981-09-01 00:00:00

  • [Myopic implant of the posterior chamber using a flexible Collamer lens].

    abstract:BACKGROUND:The purpose of this study was to report results, effectiveness and safety of implanting a negative collagen/HEMA copolymer posterior chamber phakic intraocular lens in moderate to highly myopic eyes. MATERIAL AND METHODS:23 eyes from 12 patients with a mean preoperative spherical equivalent refraction of - ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2002-30666

    authors: Roy S,Tritten JJ

    更新日期:2002-04-01 00:00:00

  • [Survival after treatment for malignant choroidal melanoma: comparison between conservative therapy (Ru106/Rh106 applicator) and enucleation with and without postoperative irradiation to the orbit; 1960 to 1979].

    abstract::The survival rate was calculated using the life table method in 1,501 patients suffering from choroidal melanomas and treated in 10 eye hospitals in the GDR between 1960 and 1979. The results of treatment by (1) enucleation, (2) enucleation with postoperative irradiation of the orbit and (3) local irradiation with 106...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1054399

    authors: Kiehl H,Kirsch I,Lommatzsch P

    更新日期:1984-01-01 00:00:00

  • [Autosome dominant vitreoretinal dystrophy with skeletal dysplasia in one generation].

    abstract::We report on ten patients of four generations with autosomal dominant vitreoretinal dystrophy with different manifestation. The ophthalmological findings are retinal detachment, retinal holes, retinoschisis, lattice and snowflake degeneration, vitreoretinal adhesions, chorioretinal atrophy and peripheral pigment epith...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1045954

    authors: Lang GE,Laudi B,Pfeiffer RA

    更新日期:1991-03-01 00:00:00

  • Cilioretinal artery occlusion combined with central retinal vein occlusion - a report of two cases and review of the literature.

    abstract:BACKGROUND:We describe the clinical findings and course of cilioretinal artery occlusion (CAO) combined with central retinal vein occlusion (CRVO) in two patients and present a review of the relevant literature. HISTORY AND SIGNS:Case 1: An otherwise healthy 24-year-old woman presented to the emergency unit with a pai...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章,评审

    doi:10.1055/s-0029-1245291

    authors: Theoulakis PE,Livieratou A,Petropoulos IK,Lepidas J,Brinkmann CK,Katsimpris JM

    更新日期:2010-04-01 00:00:00

  • [Bilateral papilledema of unknown etiology in childhood].

    abstract::The author reports on a number of cases of bilateral papilledema of unknown etiology. The condition was presumably caused by a formen virus infection. The symptoms were indicative of increased intracranial pressure; the possibility of a brain tumor therefore had to be ruled out. The results of the neurological examina...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Szabó M

    更新日期:1987-11-01 00:00:00

  • [Results of long-term treatment of glaucoma with timolol ophthalmic solution (author's transl)].

    abstract::A previous double-blind study carried out for 17 weeks on 50 patients with open-angle glaucoma reported on the results of treatment with Timolol and Pilocarpine eye drops. On completion of a long-term study with Timolol over a two-year period, the remaining findings can now be given. Of the 25 patients treated twice a...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 临床试验,杂志文章

    doi:

    authors: Merté HJ,Merkle W

    更新日期:1980-11-01 00:00:00

  • [Voluntary control of unilateral strabismus sursoadductorius].

    abstract:BACKGROUND:Strabismus with unilateral elevation in adduction is an upward deviation of the adducting eye of unknown, not necessarily paretic origin. The term "old trochlear palsy" may be erroneous since the hypertropia is not necessarily larger in downward gaze and a causative lesion can usually not be identified. We d...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1035299

    authors: Kommerell G,Mattheus S,Mühlendyck H

    更新日期:1996-08-01 00:00:00

  • [Clinical findings in phakolytic glaucoma (author's transl)].

    abstract::1300 enucleated globes were examined from 1966-1974: Among these 20 eyes (1.5%) revealed a "phacolytic glaucoma" histologically. The clinical diagnosis before enucleation were "secondary glaucoma" or "absolute glaucoma" (19) and once "uveitis dolorosa". "Phakolysis" was considered in only 3 eyes. 15 cases revealed sur...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Völcker HE,Naumann G

    更新日期:1975-05-01 00:00:00

  • [Retinal lymphoma--simulating uveitis].

    abstract::A rare form of malignant large-cell non-Hodgkin's lymphoma or reticulum cell sarcoma is confined to the eye and central nervous system (CNS). We report the case of a 62-year-old man, who presented with recalcitrant progressive uveitis in his right eye. Although lymphoma was suspected, the patient refused to undergo vi...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1045892

    authors: Arocker-Mettinger E,Huber-Spitzy V,Stur M,Haddad R,Grabner G

    更新日期:1992-09-01 00:00:00

  • [Laser treatment of diabetic maculopathy].

    abstract::The authors report on the techniques of laser treatment of diabetic maculopathy: focal direct laser coagulation of I.R.M.A. in exudative maculopathy; laser grid photocoagulation in edematous maculopathy. ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1050820

    authors: Giovannini A,Costantini G,Amato GP,Bottazzi M

    更新日期:1986-11-01 00:00:00