Relationship of acute CBF and ICP findings to neuropsychological outcome in severe head injury.

Abstract:

:Neuropsychological outcome within 1 year after severe head injury was examined in 42 conscious survivors and correlated with acute measurements of cerebral blood flow (CBF) and intracranial pressure (ICP). During acute coma, CBF was elevated in 23 patients, indicating hyperemia, and was reduced in the remaining 19 cases. Intracranial hypertension (ICP 20 mm Hg or greater) was present acutely in 15 patients and absent in 27. Occurrences of hyperemia and intracranial hypertension were significantly related. During chronic recovery, neuropsychological dysfunction was found in all cases. However, patients with hyperemia revealed greater impairment of overall intellectual and memory functions than did those with reduced flow, while patients with intracranial hypertension showed greater memory deficit than did those without ICP elevations. The results suggest that early pathophysiological events can influence subsequent neuropsychological outcome, and that chronic recovery is not homogeneous in young severely head-injured adults.

journal_name

J Neurosurg

journal_title

Journal of neurosurgery

authors

Uzzell BP,Obrist WD,Dolinskas CA,Langfitt TW

doi

10.3171/jns.1986.65.5.0630

subject

Has Abstract

pub_date

1986-11-01 00:00:00

pages

630-5

issue

5

eissn

0022-3085

issn

1933-0693

journal_volume

65

pub_type

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