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Self-reported attenuated psychotic-like experiences in help-seeking adolescents and their association with age, functioning and psychopathology.

Abstract：

OBJECTIVE:Self-rated attenuated psychotic-like experiences (APLEs) are increasingly used to screen for ultra-high-risk (UHR) across all ages. However, self-rated psychotic-like experiences (PLEs), in particular perception-related ones, were more frequent in children and adolescents, in which they possessed less clinical significance. We therefore explored the prevalence of different factors of APLEs in help-seeking adolescents, and their relationship with age, functioning and psychopathology. METHOD:As a part of the "Liberiamo il Futuro" project, help-seeking adolescents (N=171; 11-18 years, 53% male) were screened with the 92-item Prodromal Questionnaire (PQ-92). A factor analysis was performed on the PQ-92 positive items (i.e., APLEs) to identify different APLE-factors. These were assessed for their association with age, functioning and psychopathology using regression analyses. RESULTS:APLEs were very common in help-seeking adolescents, and formed four factors: "Conceptual Disorganization and Suspiciousness", "Perceptual Abnormalities", "Bizarre Experiences", and "Magical Ideation". Associations with age and functioning but not psychopathology were found for "Perceptual Abnormalities" that was significantly more severe in 11-12-year-olds, while "Conceptual Disorganization and Suspiciousness" was significantly related to psychopathology. CONCLUSION:In line with findings on PLEs, prevalence and clinical significance of APLEs, especially perception-related ones, might depend on age and thus neurodevelopmental stage, and may fall within the normal spectrum of experience during childhood. This should be considered when screening for UHR status in younger age groups.

journal_name

Schizophr Res

journal_title

Schizophrenia research

authors

Brandizzi M,Schultze-Lutter F,Masillo A,Lanna A,Curto M,Lindau JF,Solfanelli A,Listanti G,Patanè M,Kotzalidis G,Gebhardt E,Meyer N,Di Pietro D,Leccisi D,Girardi P,Fiori Nastro P

doi

10.1016/j.schres.2014.10.005

subject

Has Abstract

pub_date

2014-12-01 00:00:00

pages

110-7

issue

1-3

eissn

0920-9964

issn

1573-2509

pii

S0920-9964(14)00544-1

journal_volume

160

pub_type

杂志文章,多中心研究

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