An enzyme immunoassay for rapid isotyping of monoclonal antibodies.

Abstract:

:An enzyme-immunoassay has been developed for rapid isotyping of murine monoclonal antibodies. This assay has several advantages over the commonly used typing methods. It does not require the presence of specific antigen. Typing plates can be prepared in advance and stored frozen. Unequivocal results can be obtained in 2 h, and the urease indicator system produces a vivid colour change that can be read visually.

journal_name

Pathology

journal_title

Pathology

authors

Gardner ID

doi

10.3109/00313028509063727

subject

Has Abstract

pub_date

1985-01-01 00:00:00

pages

64-6

issue

1

eissn

0031-3025

issn

1465-3931

journal_volume

17

pub_type

杂志文章
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    abstract::We describe a case of ductal carcinoma in situ (DCIS) occurring in a fibroadenoma diagnosed by fine needle aspiration (FNA) cytology. The cytological features comprised a small population of pleomorphic cells admixed with a dominant population of bland epithelial cells showing features consistent with those of a fibro...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.1080/00313029800169736

    authors: Psarianos T,Kench JG,Ung OA,Bilous AM

    更新日期:1998-11-01 00:00:00

  • Prevalence and biological behaviour of variants of papillary thyroid carcinoma: experience at a single institute.

    abstract:AIMS:There are many variants of papillary carcinoma, and some of these variants have been reported to show biological behaviours differing from that of conventional papillary carcinoma. In this study, we present our experience regarding the prevalence and prognoses of these variants of papillary carcinoma. METHODS:H&E...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.1080/00313020802320630

    authors: Ito Y,Hirokawa M,Uruno T,Kihara M,Higashiyama T,Takamura Y,Miya A,Kobayashi K,Matsuzuka F,Miyauchi A

    更新日期:2008-10-01 00:00:00

  • Ultrastructure of human melanosis coli with reference to its pathogenesis.

    abstract::Colonic mucosal biopsies from patients with melanosis coli were examined by electron microscopy. They showed apoptosis of colonic surface epithelial cells and phagocytosis of resulting apoptotic bodies by intraepithelial macrophages. The latter migrated to the lamina propria where intracellular degradation of the apop...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.3109/00313029309084783

    authors: Walker NI,Smith MM,Smithers BM

    更新日期:1993-04-01 00:00:00

  • Human trichostrongyliasis in Queensland.

    abstract::Trichostrongylus infection, an uncommonly reported zoonosis in Australia, is common in parts of the world where there is close human contact with herbivorous animals. We report 5 cases diagnosed in our laboratory since 1992. Over this period the laboratory has conducted over 46,000 parasitological examinations on fece...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.1080/00313029500169842

    authors: Boreham RE,McCowan MJ,Ryan AE,Allworth AM,Robson JM

    更新日期:1995-04-01 00:00:00

  • Clonal status of fibrous dysplasia.

    abstract:AIM:The purpose of this study was to elucidate the clonality of fibrous dysplasia based on X-chromosome inactivation mosaicism and polymorphism in female somatic cells at the phosphoglycerate kinase (PGK) and androgen receptor (AR) loci using microdissection technology. MATERIALS AND METHODS:Nine patients with fibrous...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.1080/00313020801911496

    authors: Gong L,Zhang W,Su Q

    更新日期:2008-06-01 00:00:00

  • Ulex europaeus agglutinin-1 binding in hereditary bowel cancer.

    abstract::Ulex europaeus agglutinin-1 (UEA-1) binds specifically to alpha-L-fucose, the terminal sugar of blood group substances H2 and Ley the expression of which is confined mainly to the proximal colon. The aim of the study was to determine whether there is neo-expression of alpha-L-fucose in the normal appearing mucosa of t...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.3109/00313029309084782

    authors: Jass JR,Allison LJ,Stewart SM,Lane MR

    更新日期:1993-04-01 00:00:00

  • The fetal adrenal gland: definitive cortex cystic change, lipid patterns, and their relationship to fetal disease and maturity.

    abstract::A study of 103 fetal adrenals obtained from stillborn fetuses and those dying in the neonatal period was performed to assess the significance of definitive cortex cystic change, compact cell change and lipid patterns, and their relationship to other pathological processes. The findings confirm that these changes are m...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.3109/00313028409068543

    authors: Delprado WJ,Baird PJ

    更新日期:1984-07-01 00:00:00

  • The prognostic significance of the BRAF V600E mutation in papillary thyroid carcinoma detected by mutation-specific immunohistochemistry.

    abstract:AIMS:BRAF mutation has been shown in a large meta-analysis to be an independent prognostic marker for papillary thyroid carcinoma (PTC) with poorer survival and higher recurrence rates. METHODS:We studied prevalence of BRAF mutation in 77 patients with PTC from an Australian cohort using competitive polymerase chain r...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.1097/PAT.0000000000000008

    authors: McKelvie PA,Chan F,Yu Y,Waring P,Gresshoff I,Farrell S,Williams RA

    更新日期:2013-12-01 00:00:00

  • Histological assessment of apoptotic cell death in cardiomyopathies.

    abstract::Apoptosis in the myocardium is complex and often difficult to recognise. Myocyte apoptosis is scattered across the myocardial wall and is restricted to individual cells. In the present study, we describe the amount of apoptosis in 50 endomyocardial biopsies taken from 50 patients with dilated cardiomyopathy, in 14 hea...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:

    authors: Kavantzas NG,Lazaris AC,Agapitos EV,Nanas J,Davaris PS

    更新日期:2000-08-01 00:00:00

  • Eccrine syringofibroadenoma: a report of 2 cases.

    abstract::Eccrine syringofibroadenoma is a rare benign tumor of the skin arising from the acrosyringeal portion of the eccrine duct. The tumor was first described by Mascaro in 1963, and since then only 8 case reports in 6 publications have been documented. This lesion is likely to be misdiagnosed both clinically and histologic...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.3109/00313029109063580

    authors: Billson VR,Dyall-Smith DJ

    更新日期:1991-07-01 00:00:00

  • The enigma of struma ovarii.

    abstract::Since its first description in the early part of the twentieth century, struma ovarii has elicited considerable interest because of its many unique features; however, at present a number of aspects remain enigmatic. Although the typical presentation is that of a pelvic mass, unusual clinical manifestations such as hyp...

    journal_title:Pathology

    pub_type: 杂志文章,评审

    doi:10.1080/00313020601123979

    authors: Roth LM,Talerman A

    更新日期:2007-02-01 00:00:00

  • Nodular fasciitis: an analysis of 250 patients.

    abstract::A clinicopathological analysis was made of data from 250 cases of nodular fasciitis. These benign nodules usually occurred in young and middle-aged adults in the 4th and 5th decades, most often in the forearm (27%) followed by the thigh (17%) and the upper arm (12%), and grew rather rapidly to reach a mean diameter of...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.3109/00313028409059097

    authors: Shimizu S,Hashimoto H,Enjoji M

    更新日期:1984-04-01 00:00:00

  • Serum prohepcidin concentrations in rheumatoid arthritis.

    abstract:AIM:Hepcidin, a recently identified peptide, acts as a central regulator of iron metabolism. It is regarded as a factor regulating the uptake of dietary iron and its mobilisation from macrophages and hepatic stores. It is considered as a mediator of anaemia of inflammation. The aim of this study was to assess whether s...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.1080/00313020802436840

    authors: Jayaranee S,Sthaneshwar P,Sokkalingam S

    更新日期:2009-02-01 00:00:00

  • Hepatic granuloma in a man from North America caused by a nymph of Linguatula serrata.

    abstract::A calcified nodule on the liver of a 62-year-old man from North Carolina, USA, contained a degenerated nymph of Linguatula serrata. The nodule was incidentally discovered at laparotomy for malignant lymphoma and cholelithiasis. The cuticle was all that remained of the parasite, but sclerotized openings and large spine...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.3109/00313028809066635

    authors: Baird JK,Kassebaum LJ,Ludwig GK

    更新日期:1988-04-01 00:00:00

  • Papillary cystic tumor of the pancreas coexisting with hairy cell leukemia.

    abstract::The coexistence of a pancreatic papillary cystic tumor with hairy cell leukemia is reported. To the best of our knowledge this association has never been published. A 41-year-old man diagnosed with hairy cell leukemia developed a second malignancy that corresponded to a papillary cystic pancreatic tumor. The patient u...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:

    authors: Acebo E,Rodilla IG,Torío B,Hernando M,García de Polavieja M,Morales D,Seco I,Bermudez A

    更新日期:2000-08-01 00:00:00

  • TROP-2 immunohistochemistry: a highly accurate method in the differential diagnosis of papillary thyroid carcinoma.

    abstract::We aimed to evaluate the diagnostic utility of the novel immunohistochemical marker TROP-2 on thyroid specimens (226 tumours and 207 controls). Whole slide immunohistochemistry was performed and scored by automated digital image analysis. Non-neoplastic thyroid, follicular adenomas, follicular carcinomas, and medullar...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.1016/j.pathol.2016.04.002

    authors: Bychkov A,Sampatanukul P,Shuangshoti S,Keelawat S

    更新日期:2016-08-01 00:00:00

  • Hemorrhagic lymphadenopathy as a presenting feature of primary al amyloidosis.

    abstract::Lymphadenopathy associated with hemorrhage as a presenting feature of primary (AL) amyloidosis has not previously been described. We report two such cases one of whom had an acquired factor X and IX deficiency. The clinical presentations were characterized by sudden spontaneous enlargement of lymph nodes followed by p...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.1080/003130200104510

    authors: Hanley JP,MacLean FR,Evans JL,Colls BM,Robinson BA,Patton WN,Heaton DC

    更新日期:2000-02-01 00:00:00

  • Xanthogranulomatous endometritis: case report.

    abstract::A case of chronic endometritis with unusual histological features due to the presence of abundant foam cells and lipid material is described. The presence of foam cells, abundant intra- and extracellular lipid together with other inflammatory cells in the absence of endometrial hyperplasia or carcinoma warrants the di...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.3109/00313027809063496

    authors: Barua R,Kirkland JA,Petrucco OM

    更新日期:1978-04-01 00:00:00

  • T-cell rich, Ki-1-positive post-transplant lymphoproliferative disorder: a previously undescribed variant following liver transplant.

    abstract::Post-transplant lymphoproliferative disorders (PTLD) are a consequence of the immunosuppressive therapy following organ transplant. We describe a patient who developed PTLD seven years after liver transplant and while receiving cyclosporine and prednisone. Magnetic resonance imaging demonstrated a paraspinal mass exte...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.1080/00313029800169636

    authors: Grosso LE,Bee CS

    更新日期:1998-11-01 00:00:00

  • Reliability of the porphobilinogen screening assay.

    abstract::A survey conducted by the Australian Association of Clinical Biochemists Porphyrin Working Party on urinary porphobilinogen screening showed good sensitivity (75-97.5%). This is contrary to reports in the literature and to our own observations. We therefore assessed a widely used screening method (Watson-Schwartz) and...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.3109/00313029009086660

    authors: Buttery JE,Carrera AM,Pannall PR

    更新日期:1990-10-01 00:00:00

  • Reversed polarity of the glandular epithelial cells in micropapillary carcinoma of the large intestine and the EMA/MUC1 immunostain.

    abstract::Micropapillary carcinoma of the colon and rectum is associated with an adverse prognosis. This tumour type displays reverse polarity of the tumour cells and is stated to be characterised by an inside-out epithelial membrane antigen (EMA)/MUC1 staining. Nine cases of primary colorectal carcinoma and one omental metasta...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.1097/PAT.0000000000000144

    authors: Cserni G

    更新日期:2014-10-01 00:00:00

  • Recent advances in the diagnosis of soft tissue tumours.

    abstract::Soft tissue tumours are relatively rare, but are diagnostically challenging as they comprise a large spectrum of diagnostic entities. Substantial advances have been made in recent years in identifying the underlying recurrent chromosomal and genomic alterations in a significant subset of soft tissue tumours, and this ...

    journal_title:Pathology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pathol.2017.07.007

    authors: Schaefer IM,Fletcher CDM

    更新日期:2018-01-01 00:00:00

  • Predilection of experimental arterial aneurysms for dietary-induced lipid deposition.

    abstract::In 14 stock rabbits experimental aneurysms (saccular, fusiform or berry) were produced on the common carotid artery or the aorta by microvascular surgery using a modification of the venous pouch technique. The animals were given a cholesterol-rich diet at varying times postoperatively to determine the susceptibility o...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.3109/00313028109086647

    authors: Stehbens WE

    更新日期:1981-10-01 00:00:00

  • Digital papillary adenocarcinoma: a tumour that should be considered in the differential diagnosis of neoplasms involving the digits.

    abstract:BACKGROUND:Digital papillary adenocarcinoma (DPA) is a rare malignant adnexal tumour that occurs almost exclusively in a digital location. Only two case series have been reported previously. AIMS:To document the clinical and histopathological findings in a series of patients with DPA. RESULTS:Of the 8 patients identi...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.1097/PAT.0b013e32835af778

    authors: Scolyer RA,Karim RZ,Thompson JF,Stretch JR,McCarthy SW,Murali R

    更新日期:2013-01-01 00:00:00

  • A scanning electron microscope study of isolated glomeruli in glomerulonephritis.

    abstract::Glomeruli from 48 cases of glomerulonephritis (Gn) were isolated and studied by means of the scanning electron microscope (SEM). Overall glomerular loss due to processing was 2.4%. SEM of these isolated glomeruli showed good preservation of glomerular structure. Changes of the podocyte cell body and its foot processes...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.3109/00313028309084701

    authors: Ng WL,Chan KW,Ma L

    更新日期:1983-04-01 00:00:00

  • Thermolabile methyltetrahydrofolate reductase associated with unusual venous and arterial thromboses.

    abstract::We report a patient with unusual venous and arterial thromboses in association with the common thermolabile methyltetrahydrofolate (MTHFR) variant. The patient responded directly to folate supplementation. To our knowledge, this is the first report describing hyperhomocysteinemia in association with this type of throm...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.1080/003130299105502

    authors: Hall TN,Ramakrishnan LL,Leahy MF

    更新日期:1999-02-01 00:00:00

  • Blood alcohol analysis: a comparison of the gas-chromatographic assay with an enzymatic assay.

    abstract::Ethanol in blood was assayed by 2 currently available procedures: a commercial kit enzymatic assay and a gas chromatographic procedure. Both methods were performed with commercially available materials and equipment. Results by the 2 procedures agreed well. For the 192 specimens studied, the correlation coefficient wa...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.3109/00313028409059096

    authors: Taylor GF,Turrill GH,Carter NG

    更新日期:1984-04-01 00:00:00

  • Early and late effects of wound healing on development of colon tumours in a model of colon carcinogenesis by 1,2-dimethylhydrazine in the rat.

    abstract::The early and late effects of wound healing on tumour development at a distant site were evaluated morphologically in an experimental model of colon carcinogenesis induced by 1,2-dimethylhydrazine (DMH). Random bred male Wistar rats were given subcutaneous injections of DMH (20 mg/kg) or saline, once a week, for eight...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:

    authors: Sequeira JL,Kobayasi SS,Rodrigues MA

    更新日期:2000-11-01 00:00:00

  • Extraskeletal osteosarcoma of the scalp.

    abstract::A rare case of extraskeletal osteosarcoma of the scalp in a 56-year-old woman is described. At presentation she was found to have an 8-cm diameter, tender, firm, exophytic scalp tumor. MRI scan confirmed absence of underlying skeletal origin and showed extension along the subcutaneous plane. The tumor was excised and ...

    journal_title:Pathology

    pub_type: 杂志文章

    doi:10.1080/003130200104457

    authors: Pillay P,Simango S,Govender D

    更新日期:2000-05-01 00:00:00

  • Heterogeneity of primary malignant melanomas in oral mucosa: an analysis of 43 cases in Japan.

    abstract::In contrast to Caucasians, Japanese people have a relatively high incidence of malignant melanoma in the oral cavity and volar-subungual skin. The classification of oral melanoma has not been established. We report 7 new cases of oral melanoma, with a review of 36 cases, published in Japan, between 1970 and 1984. Most...

    journal_title:Pathology

    pub_type: 杂志文章,评审

    doi:10.3109/00313028809059498

    authors: Umeda M,Mishima Y,Teranobu O,Nakanishi K,Shimada K

    更新日期:1988-07-01 00:00:00