[Pressure lowering effect and side effects of 0.5% and 1.0% levobunolol eyedrops, compared with 0.5% timolol eyedrops in patients with open-angle glaucoma].

Abstract:

:Fifty patients with open-angle glaucoma were treated twice daily for one year with topical 0.5% levobunolol, 1% levobunolol, or 0.5% timolol. Both concentrations of levobunolol were as effective as timolol in reducing intraocular pressure over the one-year period. At the concentrations tested, levobunolol and timolol decreased heart rate to a similar extent, suggesting that systemic absorption occurred after topical instillation. In all three treatment groups, clinically insignificant changes in blood pressure were observed sporadically throughout the one-year period. Very few clinically significant toxic ocular reactions were observed.

journal_name

Klin Monbl Augenheilkd

authors

Stryz JR,Merté HJ

doi

10.1055/s-2008-1054395

subject

Has Abstract

pub_date

1985-12-01 00:00:00

pages

537-44

issue

6

eissn

0023-2165

issn

1439-3999

journal_volume

187

pub_type

临床试验,杂志文章,随机对照试验
  • [Anti-inflammatory effect of topical diclofenac sodium (Voltarène Ophta) after argon laser trabeculoplasty: preliminary results of a prospective double-blind method].

    abstract::Using the laser flare-cell meter (LFMC), we have previously determined the intensity and pattern of post-ALT ocular inflammation. Inflammation peak occurs 48 hours after ALT and clinically relevant inflammation is seen in 100% of pigmentary glaucomas (PIG), 75% of pseudoexfoliative glaucomas (PEXG) but only in 25% of ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1055/s-2008-1045765

    authors: Herbort CP,Mermoud A,Schnyder C,Pittet N

    更新日期:1992-05-01 00:00:00

  • [Prognosis in repeat keratoplasty: per indication analysis in a large monocentric cohort].

    abstract:BACKGROUND:Data from national graft registries suggests a limited prognosis in the group of all repeat keratoplasties. This group might rather consist mostly of cases already classified as high risk in the first place, however. Thus, repeat keratoplasties in normal risk indications might have a substantially better pro...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1027127

    authors: Böhringer D,Reinhard T

    更新日期:2008-01-01 00:00:00

  • [Clinical value of scanning laser polarimetry in glaucoma diagnostics].

    abstract::The term glaucoma is used as a melting pot of many different diseases which have in common that the retinal ganglion cells and their axons are damaged. Untreated, apoptosis can be induced causing ganglion cell death which subsequently leads to typical glaucomatous damage at the optic nerve head, scotomas of the visual...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章,评审

    doi:10.1055/s-0031-1299246

    authors: Kremmer S,Anastassiou G,Selbach JM

    更新日期:2012-02-01 00:00:00

  • [A New Way to Look Up. Solar Retinopathy Risks and Methods of Prevention Prior to the 2015 Solar Eclipse].

    abstract::A solar eclipse is an impressive natural phenomenon that was last experienced in Europe in 2006. Last year, on March 20th 2015, a solar eclipse was visible in much of Europe. Solar retinopathy is a recognised potentially sight threatening condition that has been associated with direct or unprotected sun gazing. Public...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-0042-111727

    authors: Tsatsos M,MacGregor C,Gousia D,Moschos M,Detorakis E

    更新日期:2017-06-01 00:00:00

  • [Assessment of lesions in various sections of the visual pathway].

    abstract::The suitability of ultrasonography, computer tomography and Octopus perimetry is illustrated with reference to an investigation carried out in 60 patients. First, the characteristic symptoms are described, depending on the localization of the lesion in the visual pathway. Then the advantages and disadvantages of the v...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1055172

    authors: Wochesländer E,Bartl G,Ladurner G

    更新日期:1982-08-01 00:00:00

  • [Principals and clinical applications of optical coherence tomography in glaucoma].

    abstract::Optical coherence tomography (OCT) supplies morphological information from different retinal layers. In glaucoma, analysis of the nerve fiber layer is gaining more and more significance: Losses in this layer often precede by years functional losses in the visual field and end up in optical nerve head changes. OCT offe...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章,评审

    doi:10.1055/s-2006-926820

    authors: Parasta AM,Fabian E,Duncker G

    更新日期:2006-08-01 00:00:00

  • [Modification of the course of chronic intraocular inflammations by sunlight (Israel study)].

    abstract::Natural treatment methods are currently becoming more and more interesting, in part due to recent results of experimental and clinical research. It has been shown that light of certain wavelengths has a systemic immunosuppressive effect. It therefore seemed logical to expose patients suffering from chronic iridocyclit...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1050221

    authors: Manthey KF,Danielmeyer F

    更新日期:1988-07-01 00:00:00

  • [Effect of corneal collagen shields and epithelial growth promoting factors on epithelialization of the human cornea].

    abstract:PATIENTS AND METHODS:In 28 patients after perforating keratoplasty followed by epithelial abrasion of the transplant the period required for epithelial closure with a therapy including collagen shields and the growth stimulating factors vitamin A and Epidermal Growth Factor (EGF) was determined. RESULTS:A significant ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1055/s-2008-1045517

    authors: Kammann JP,Vollenberg C

    更新日期:1994-10-01 00:00:00

  • [Lowering of intraocular pressure by aqueous solution of bupranolol in chronic uncomplicated glaucoma simplex (author's transl)].

    abstract::In two previous studies the effects of topically applied 1% and 0.2% solutions of bupranolol on intraocular pressure were investigated in 21 and respectively 20 eyes with chronic uncomplicated open-angle glaucoma.--As early as 30 minutes after both solutions a very significant pressure drop, without concomittant pupil...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Oancea I,Trif V

    更新日期:1979-05-01 00:00:00

  • [Binocular diplopia after cataract operation].

    abstract:BACKGROUND:The development of binocular diplopia after cataract surgery is a serious complication. The present retrospective study aims to improve our understanding of this phenomenon and its prevention. PATIENTS AND METHODS:A series of 11 patients with binocular diplopia after cataract surgery under local retrobulbar...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 临床试验,杂志文章

    doi:10.1055/s-2006-926572

    authors: Boldea R,Klainguti G

    更新日期:2006-05-01 00:00:00

  • [Removal of centrally located subretinal perfluorocarbon liquid].

    abstract:BACKGROUND:Subretinal perfluorocarbon liquid (PFCL) droplets are occassionally seen after vitreoretinal surgery for retinal detachment. Usually they are located peripherally without causing complications and therapeutic consequences. In contrast, centrally located PFCL droplets affect final visual outcomes. In animal e...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-0031-1299159

    authors: Pfriem M,Hoerauf H

    更新日期:2012-07-01 00:00:00

  • [Unilateral type III (Hida) lattice stromal corneal dystrophy].

    abstract:BACKGROUND:All three types of lattice stromal dystrophy of the cornea use to appear bilaterally. We report on two patients with an unilateral manifestation of type III. PATIENTS:A 54 and a 87-years-old man presented a strictly unilateral atypical lattice dystrophy of the cornea and suffered from corneal erosion. Strik...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1045681

    authors: Seitz B,Weidle E,Naumann GO

    更新日期:1993-10-01 00:00:00

  • Intravitreal triamcinolone injection for unresponsive cystoid macular oedema in probable Behçet's disease as an additional therapy.

    abstract:BACKGROUND:We present the description of a successful outcome of intravitreal triamcinolone injection (IVTA) in a patient with cystoid macular oedema (CME) and severe retinal vasculitis suggestive of ocular Behçet's disease. HISTORY AND SIGNS:A healthy 32 year-old Caucasian man presented initially with right retinal v...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1027351

    authors: Oueghlani E,Pavésio CE

    更新日期:2008-05-01 00:00:00

  • [Useful examinations and therapies in immunologic diseases].

    abstract::Screening by immune disease is useful for one part in the various ocular inflammatory processes, uveitis, vasculitis, (epi)scleritis and myositis, for the other in collagen diseases with possible eye complications. The various forms of uveitis can be related either to rheumatic disease, to some HLA antigen, to a micro...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章,评审

    doi:10.1055/s-2008-1045632

    authors: Martenet AC

    更新日期:1993-05-01 00:00:00

  • [Unusual presentation of retinoblastoma].

    abstract::Among the 185 retinoblastoma patients seen at the Lausanne Retinoblastoma Clinic from 1963-1993, 24 (14%) first presented with another sign than classical leukocoria (60.5%) or strabismus (21.5%). Most of these atypical signs were related to inflammatory complications of unrecognized retinoblastoma; they consisted of ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1035546

    authors: Balmer A,Gailloud C,Munier F,Lendi B,Uffer S

    更新日期:1994-05-01 00:00:00

  • [Diagnosis and treatment of intraocular tumors in the child].

    abstract:PURPOSE:To remind of the absolute necessity for early diagnosis in the presence of ocular signs in children giving rise to possible intraocular tumours. METHOD:Based on our own experience of intraocular tumours in children, together with findings from the literature, diagnostic criteria and methods of treatment are pr...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章,评审

    doi:10.1055/s-2001-15884

    authors: Balmer A,Munier F

    更新日期:2001-05-01 00:00:00

  • [Genodermatosis with changes in eyes not previously described (author's transl)].

    abstract::Report on a patient with several symptoms which had not previously occurred together. The main symptom is palmoplantar keratosis; further alterations were kypho-skoliosis, brachytelephalangia of the thumbs, and in the eyes, keratoconus, a cataract and electroretinographic alterations. ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1057732

    authors: Richard G,Wreesmann P

    更新日期:1980-12-01 00:00:00

  • [Investigations into mucous membrane compatibility using the Endorfer Jod-Thermalsole treatment of the conjunctivae of rabbits (author's transl)].

    abstract::The conjunctivae of nine rabbits of the same breed were used to compare the local compatibility of the Endorfer Jod-Thermalsole with that of a physiological NaCl solution. The neuroleptanalgesics were administered using perfusion techniques. The reddening thus caused was used to measure the degree of inflammation. The...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1055295

    authors: Hirsch E

    更新日期:1981-01-01 00:00:00

  • [Basic in vitro studies on VEGF inhibition with aflibercept: similarities and differences to other VEGF-binding therapeutic proteins].

    abstract::Patients suffering from various retinal diseases benefit from therapies directed against the vascular endothelial growth factor (VEGF). Aflibercept (Eylea) is another VEGF-binding protein available for intravitreal injection, in addition to the antibody bevacizumab (Avastin) and the F(ab) fragment ranibizumab (Lucenti...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章,评审

    doi:10.1055/s-0034-1383142

    authors: Lang GE,Lang GK,Deissler HL

    更新日期:2015-03-01 00:00:00

  • [Laser sclerostomy: an alternative to current surgical filtering procedures. Experimental studies].

    abstract::A new filtering procedure, laser sclerostomy, was performed in 12 rabbit eyes by combined application of an argon and a YAG laser. In 10 cases an open fistula connecting the anterior chamber and the subconjunctival space could be demonstrated histologically. As neither the conjunctiva nor the globe are incised "ab ext...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1046356

    authors: Wetzel W,Duncker G,Schumacher C,Dölle W

    更新日期:1989-03-01 00:00:00

  • [Allograft rejection reactions after keratoplasty (author's transl)].

    abstract::Immune reactions against corneal transplants cause most of the graft failures during the first 24 months after keratoplasty. This is partly due to inadequate diagnosis and therapy. After a short discussion of the experimental and clinical background, different kinds of characteristic immune reactions are demonstrated ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Sundmacher R

    更新日期:1977-11-01 00:00:00

  • [Efficiency and Therapy Safety of Fractionated Cyclophotocoagulation with up to Ten Laser Spots for Advanced Primary Open-Angle and Pseudoexfoliation Glaucoma].

    abstract:BACKGROUND:Various procedures are available for the treatment of advanced glaucoma. We examined the efficacy and safety of fractionated cyclophotocoagulation (CPC) with up to ten laser spots for advanced primary open-angle glaucoma (POAG) and pseudoexfoliation (PEX) glaucoma treated with maximal topical therapy or eye-...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/a-1057-9699

    authors: Grohmann C,Farrokhi S,Klemm M

    更新日期:2020-02-03 00:00:00

  • [Demonstration of the tonographic effect in YAG laser trabeculoplasty in chronic glaucoma].

    abstract::In a pilot study comprising 16 eyes of 16 patients with chronic open-angle glaucoma the tonographic outflow facility was examined before and after Nd-YAG laser treatment of the trabecular meshwork. For evaluation of the facility effect of laser trabeculoplasty, the tonographic record between the third and seventh minu...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1051010

    authors: Schrems W,Sold J,Krieglstein GK,Leydhecker W

    更新日期:1985-09-01 00:00:00

  • [Therapy of herpetic diseases of the anterior eye segment].

    abstract::Clinico-virologic investigations and the availability of the new antiviral drug Acyclovir have changed our therapeutic approach to deep herpetic diseases. Treatment of the symptoms alone with steroids should now be avoided. Basic treatment should consist of optimal dosages of Acyclovir. However, additional steroid the...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1050949

    authors: Sundmacher R

    更新日期:1985-06-01 00:00:00

  • [Two patients with xerophthalmia].

    abstract:BACKGROUND:Xerophthalmia, the eye manifestation of vitamin A deficiency, is one of the main reasons of blindness in developing countries but is rare in industrial countries. PATIENTS:We report on 2 cases of night blindness and conjunctival and corneal xerosis because of hypovitaminosis A. One patient developed vitamin...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2000-10386

    authors: Horwath J,Stelzl U,Bachernegg M,Langmann A

    更新日期:2000-07-01 00:00:00

  • [Vibration, a new way of cutting in ophthalmic surgery (author's transl)].

    abstract::Rapid movement (vibration) of a movable scissor blade against a stationary blade at alternating current frequency (50 Hz) provides considerable improvement of cutting power and decreases distortion and crushing of the tissue. The article describes vibrational scissors for cataract surgery. ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Spitznas M,Kreiger A

    更新日期:1975-04-01 00:00:00

  • [Malignant teratoid medulloepithelioma of the ciliary body and glial fibrillary acidic protein. Clinical, histochemical and immunohistochemical findings].

    abstract::In a four-year-old boy a malignant teratoid medulloepithelioma of the ciliary body was removed by means of an 11.0 X 11.0 mm "block excision". Two years later the patients visual acuity was 0.6. The lesion originates in the nonpigmented ciliary epithelium, extending along the lens equator to the pupillary zone and thr...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1051036

    authors: Holbach L,Völcker HE,Naumann GO

    更新日期:1985-10-01 00:00:00

  • [Individual postoperative refraction after cataract surgery -- a comparison of optical and acoustical biometry].

    abstract:BACKGROUND:Optical biometry with the IOL-Master is an innovative technique that claims to improve the refractive results of cataract surgery compared to acoustical biometry. METHODS:In 140 consecutive non-selected eyes prior to cataract surgery firstly an optical biometry (IOL-Master, Zeiss, V.2.02) and secondly an ul...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2004-813385

    authors: Kutschan A,Wiegand W

    更新日期:2004-09-01 00:00:00

  • [Suggestions for the design of a modern anomaloscope].

    abstract::Three variants of a new anomaloscope principle are described. This principle is distinguished by the fact that for generation of the mixed color and the reference color three interference filters with narrow band widths are used instead of an expensive dispersion prism. In the first variant the brightness of the mixed...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1055221

    authors: Bockelmann WD

    更新日期:1982-10-01 00:00:00

  • [Light phenomena in the dislocation of artificial lenses in a model trial].

    abstract::Light phenomena evoked by a Kratz elliptical posterior chamber lens, a Mark Choyce IX anterior chamber lens, and a four-loop Binkhorst anterior chamber lens were investigated in a model with pupils of various sizes. Besides monocular diplopia, the edge of the lens produces scattered light phenomena which vary accordin...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1050471

    authors: Aust W

    更新日期:1987-07-01 00:00:00