Endoscopic management of nonvariceal, nonulcer upper gastrointestinal bleeding.

Abstract:

:Upper gastrointestinal bleeding (UGIB) is the most common emergency condition in gastroenterology. Although peptic ulcer and esophagogastric varices are the predominant causes, other conditions account for up to 50% of UGIBs. These conditions, among others, include angiodysplasia, Dieulafoy and Mallory-Weiss lesions, gastric antral vascular ectasia, and Cameron lesions. Upper GI cancer as well as lesions of the biliary tract and pancreas may also result in severe UGIB. This article provides an overview of the endoscopic management of these lesions, including the role of novel therapeutic modalities such as hemostatic powder and over-the-scope-clips.

authors

Tjwa ET,Holster IL,Kuipers EJ

doi

10.1016/j.gtc.2014.08.004

subject

Has Abstract

pub_date

2014-12-01 00:00:00

pages

707-19

issue

4

eissn

0889-8553

issn

1558-1942

pii

S0889-8553(14)00094-6

journal_volume

43

pub_type

杂志文章,评审
  • Symptomatic presentations of the irritable bowel syndrome.

    abstract::Because functional bowel disorders have no reliable markers, they must be defined by their symptoms. The various constellations of symptoms (syndromes) may have different mechanisms, differential diagnoses, and treatments. Therefore, precise classification is important on clinical and scientific grounds. Functional bo...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:

    authors: Thompson WG

    更新日期:1991-06-01 00:00:00

  • Gastroesophageal reflux disease: new concepts in pathophysiology.

    abstract::The explanation as to why gastroesophageal reflux disease develops remains unanswered. We have learned much about the regulation of LES pressure, the single most important factor in the development of reflux disease. Our understanding of factors involved in the clearance of refluxed contents has also increased. The pr...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:

    authors: Ogorek CP,Cohen S

    更新日期:1989-06-01 00:00:00

  • Occult gastrointestinal bleeding.

    abstract::Occult gastrointestinal bleeding is loss of blood into the digestive tract that is not apparent to the patient or physician by physical examination. It is detected by examination of the stool for chemical evidence of blood by laboratory techniques or by the observation of iron deficiency. The presence of occult blood ...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:

    authors: Richter JM

    更新日期:1994-03-01 00:00:00

  • Morbid obesity: definitions, epidemiology, and methodological problems.

    abstract::This article defines obesity, ideal body weight, morbid obesity, and indexes of overweight, pointing out some of the difficulties in studies of the epidemiology of morbid obesity. ...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章

    doi:

    authors: Kral JG,Heymsfield S

    更新日期:1987-06-01 00:00:00

  • Biliary atresia.

    abstract::BA is a rare disease of unclear etiology; nevertheless, its impact in the field of pediatric hepatology is significant. It is the most common surgically correctable cause of neonatal cholestasis and is the most common pediatric disease referred for liver transplantation. Little progress has been made with regard to im...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/s0889-8553(03)00049-9

    authors: Haber BA,Russo P

    更新日期:2003-09-01 00:00:00

  • Histologic precursors of gastrointestinal tract malignancy.

    abstract::Precursor lesions in the GIT include flat dysplasias, adenomas, dysplasia superimposed on nonneoplastic polyps, endocrine cell dysplasia, ACF, and condyloma accuminatum. Interobserver variability can be a problem in reporting dysplasia, and ancillary techniques including flow cytometry, image analysis, proliferation m...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/s0889-8553(02)00007-9

    authors: Haber MM

    更新日期:2002-06-01 00:00:00

  • Palliation of malignant ascites.

    abstract::The management of recurrent, symptomatic malignant ascites can be problematic for physicians and patients. The most common, low-risk method is large-volume paracentesis. Patient disease progression often leads to rapid reaccumulation of ascites, which requires frequent return visits to the hospital for symptom managem...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/j.gtc.2005.12.006

    authors: Rosenberg SM

    更新日期:2006-03-01 00:00:00

  • Improving Mental Health for the Mother-Infant Dyad by Nutrition and the Maternal Gut Microbiome.

    abstract::Perinatal mood and anxiety disorders (PMAD) have significant negative impacts on mother and child, yet treatments are limited. Adequate nutrition during the perinatal period is essential to maternal and infant health, including maternal mental health and the child's neurologic and neuropsychiatric development. Nutriti...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/j.gtc.2019.04.007

    authors: Bernabé BP,Tussing-Humphreys L,Rackers HS,Welke L,Mantha A,Kimmel MC

    更新日期:2019-09-01 00:00:00

  • Current Perspectives on Gastric Cancer.

    abstract::Gastric cancer (GC) is third leading cause of cancer-related death. Only 28.3% of new GC cases survive more than 5 years. Although incidence has declined in the United States, an increase is estimated for 2016. Risk factors include sex (risk is higher in men), Helicobacter pylori infection, heredity, and lifestyle. GC...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/j.gtc.2016.04.002

    authors: Marqués-Lespier JM,González-Pons M,Cruz-Correa M

    更新日期:2016-09-01 00:00:00

  • Update on Therapeutic Drug Monitoring in Crohn's Disease.

    abstract::In patients with Crohn's disease on biologic medications, the use of therapeutic drug monitoring leads to a personalized approach to optimize treatment. Using an algorithmic approach, measurement of drug concentrations and anti-drug antibodies can be used to improve treatment outcomes. Therapeutic drug concentrations ...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/j.gtc.2017.05.014

    authors: Heron V,Afif W

    更新日期:2017-09-01 00:00:00

  • Neuroimmunomodulation in the intestinal mucosa.

    abstract::The intestine contains major subdivisions of the nervous and immune systems. The lymphoid compartments of the intestine contain functionally distinguishable populations of immunologic cells and are innervated differently. The lamina propria has an extensive network of nerves using the neuropeptides SOM, SP, and VIP. S...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:

    authors: Ottaway CA

    更新日期:1991-09-01 00:00:00

  • Complementary and alternative medicine for the irritable bowel syndrome.

    abstract::Irritable bowel syndrome (IBS) is a common chronic gastrointestinal disorder, characterized by chronic or recurrent abdominal pain and bloating. Complementary and alternative medicine (CAM) is a diverse group of medical treatments that are not commonly considered to be a part of conventional medicine yet frequently us...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/j.gtc.2010.12.005

    authors: Magge S,Lembo A

    更新日期:2011-03-01 00:00:00

  • Diet, nutrients, and gastrointestinal cancer.

    abstract::Tobacco and alcohol use are strong risk factors for cancer of the upper gastrointestinal tract. Saturated fat and red meat intake also appear to increase the risk of colorectal cancer. The strongest and most consistent dietary protective factors for gastrointestinal cancer are vegetables and fruits. Some micronutrient...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/s0889-8553(05)70006-6

    authors: Hensrud DD,Heimburger DC

    更新日期:1998-06-01 00:00:00

  • Endoscopic palliation of pancreatic cancer.

    abstract::Endoscopic approaches have revolutionized the palliation of advanced pancreatic cancer. The ideal management consists of a multidisciplinary approach involving surgeons, endoscopists, radiologists, and oncologists. Concurrent advances in the fields of interventional radiology and laparoscopic surgical oncology should ...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/j.gtc.2007.04.001

    authors: Sanders M,Papachristou GI,McGrath KM,Slivka A

    更新日期:2007-06-01 00:00:00

  • Real-time histology in colonoscopy.

    abstract::Gastrointestinal endoscopy had major technological improvements and novel technologies in recent years. High-definition endoscopy has permitted an increasingly detailed view of the mucosa during colonoscopy. Filter techniques that enhance analysis of vessel and surface structures. Autofluorescence imaging relies on fu...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/j.gtc.2013.05.004

    authors: Goetz M

    更新日期:2013-09-01 00:00:00

  • Modern radiation therapy techniques for pancreatic cancer.

    abstract::Radiation therapy is a rapidly evolving field, and recent technical advances have spurred an increasing number of new treatments as well as marked improvements in previously existing treatments. Despite a growing body of published evidence demonstrating that radiotherapy for the treatment of pancreatic cancer is impro...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/j.gtc.2011.12.011

    authors: Trakul N,Koong AC,Maxim PG,Chang DT

    更新日期:2012-03-01 00:00:00

  • The role of genetics in IBS.

    abstract::Irritable bowel syndrome (IBS) is a common disorder that has been shown to aggregate in families and to affect multiple generations, but not in a manner consistent with a major Mendelian effect. Relatives of an individual with IBS are 2 to 3 times as likely to have IBS, with both genders being affected. To date, more ...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/j.gtc.2010.12.011

    authors: Saito YA

    更新日期:2011-03-01 00:00:00

  • The cellular and molecular pathogenesis of colorectal cancer.

    abstract::The development of colorectal neoplasia originates from normal colonic mucosa, progresses to the adenomatous polyp, and later may evolve into carcinoma. This procession of histologic change can be defined by a series of successive waves of clonal expansion that contain certain genetic alterations. These genetic altera...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/s0889-8553(05)70272-7

    authors: Carethers JM

    更新日期:1996-12-01 00:00:00

  • The role of endoscopy in acute recurrent and chronic pancreatitis and pancreatic cancer.

    abstract::Endoscopy plays an important role in the diagnosis and treatment of acute and chronic pancreatitis as well as pancreatic cancer. Sphincterotomy and stone removal in biliary pancreatitis, stone extraction and drainage in chronic pancreatitis, and stent implantation in pancreatic cancer are the predominant procedures. W...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/s0889-8553(05)70087-x

    authors: Jakobs R,Riemann JF

    更新日期:1999-09-01 00:00:00

  • Ascariasis.

    abstract::Ascariasis is a helminthic infection of global distribution with more than 1.4 billion persons infected throughout the world. The majority of infections occur in the developing countries of Asia and Latin America. Of 4 million people infected in the United States, a large percentage are immigrants from developing coun...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/s0889-8553(05)70263-6

    authors: Khuroo MS

    更新日期:1996-09-01 00:00:00

  • Esophageal manometry in gastroesophageal reflux disease.

    abstract::High-resolution manometry (HRM) allows nuanced evaluation of esophageal motor function, and more accurate evaluation of lower esophageal sphincter (LES) function, in comparison with conventional manometry. Pathophysiologic correlates of gastroesophageal reflux disease (GERD) and esophageal peristaltic performance are ...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/j.gtc.2013.11.005

    authors: Mello M,Gyawali CP

    更新日期:2014-03-01 00:00:00

  • Treatment of cholesterol gallstones with litholytic bile acids.

    abstract::Cholesterol gallstone disease is reversible and can be treated medically with either CDCA or UDCA. Both bile acids correct the hepatic metabolic defect that is responsible for hypersecretion of cholesterol into the bile, and both desaturate the bile. UDCA is preferred because it is more effective, desaturate the bile ...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:

    authors: Salen G,Tint GS,Shefer S

    更新日期:1991-03-01 00:00:00

  • Biopsy Diagnosis of Celiac Disease: The Pathologist's Perspective in Light of Recent Advances.

    abstract::Celiac disease is a common immune-mediated disorder that occurs in individuals with permissive genetics (HLA-DQ2/DQ8 genotype) following exposure to certain wheat proteins. The histopathologic manifestations of small intestinal mucosal injury (villus atrophy, crypt hyperplasia, and intraepithelial lymphocytosis) are w...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/j.gtc.2018.09.003

    authors: Lagana SM,Bhagat G

    更新日期:2019-03-01 00:00:00

  • Epidemiology of gallstones.

    abstract::Gallstones are common with prevalences as high as 60% to 70% in American Indians and 10% to 15% in white adults of developed countries. Ethnic differences abound with a reduced frequency in black Americans and those from East Asia, while being rare in sub-Saharan Africa. Certain risk factors for gallstones are immutab...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/j.gtc.2010.02.003

    authors: Stinton LM,Myers RP,Shaffer EA

    更新日期:2010-06-01 00:00:00

  • Constipation: evaluation and treatment.

    abstract::Constipation is a common clinical problem that comprises a constellation of symptoms that include excessive straining, hard stools, feeling of incomplete evacuation, use of digital maneuvers, or infrequent defecation. Although many conditions, such as metabolic problems, fiber deficiency, anorectal problems, and drugs...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/s0889-8553(03)00026-8

    authors: Rao SS

    更新日期:2003-06-01 00:00:00

  • The role of FDG-PET and staging laparoscopy in the management of patients with cancer of the esophagus or gastroesophageal junction.

    abstract::The effort to improve outcomes in esophageal cancer has included attempts at improving staging and patient selection. 2-Deoxy-2-[(18)F]fluoro-Dglucose positron emission tomography (FDG-PET) has been extensively studied in this context and has been widely accepted as a staging tool. Its role in restaging or assessing t...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/j.gtc.2009.01.007

    authors: Yoon HH,Lowe VJ,Cassivi SD,Romero Y

    更新日期:2009-03-01 00:00:00

  • High-definition and filter-aided colonoscopy.

    abstract::New high-resolution colonoscopes and filter technologies are allowing us to visualize more lesions and better characterize lesions within the gastrointestinal tract. In light of recent findings that flat and serrated lesions are more likely to contain invasive cancer and that even small lesions (5-10 mm) may contain a...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/j.gtc.2010.08.022

    authors: Sauk J,Hoffman A,Anandasabapathy S,Kiesslich R

    更新日期:2010-12-01 00:00:00

  • Current and future treatment of chest pain of presumed esophageal origin.

    abstract::Patients with chest pain of presumed esophageal origin should be reassured and should undergo an esophageal manometry study. In patients with spastic esophageal disorders, a trial with calcium channel blockers or low-dose antidepressants used as visceral analgesics is the best approach. Inpatients with non GERD-relate...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/S0889-8553(03)00127-4

    authors: Schmulson MJ,Valdovinos MA

    更新日期:2004-03-01 00:00:00

  • Pharmacologic therapies for obesity.

    abstract::This article examines the transitions in pharmacological therapy for obesity. It reviews the current options approved by the Food and Drug Administration and several drugs approved for other indications that can be used to treat obesity as well. Because weight regulation is complex and redundant systems protect agains...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/j.gtc.2010.01.001

    authors: Kaplan LM

    更新日期:2010-03-01 00:00:00

  • Managed care organizations and products.

    abstract::Managed care organizations and their products will continue to change in response to consumer demands, competitive pressures, and regulatory requirements. Providers who gain an understanding of the world managed care organizations live in can also expect to influence these organizations for mutual benefit. Just as man...

    journal_title:Gastroenterology clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/s0889-8553(05)70328-9

    authors: Behnke LM

    更新日期:1997-12-01 00:00:00