Abstract:
:We studied 30 necropsy cases of vascular dementia with a lacunar state. Manifestations included dementia, lack of volition, emotional lability, small-stepped gait, dysarthria, urinary incontinence, grasp reflex, pyramidal signs, paraplegia in flexion, and akinetic mutism. Pathologically, there was diffuse incomplete softening of white matter in all cases. Both lacunes and diffuse softening were found predominantly in the frontal lobes. The prominent clinical features were therefore frontal lobe symptoms, with good correlation between the symptoms and the distribution of pathologic lesions.
journal_name
Neurologyjournal_title
Neurologyauthors
Ishii N,Nishihara Y,Imamura Tdoi
10.1212/wnl.36.3.340subject
Has Abstractpub_date
1986-03-01 00:00:00pages
340-5issue
3eissn
0028-3878issn
1526-632Xjournal_volume
36pub_type
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