Abstract:
:We observed that patients with amnesia after cardiac arrest had preserved recognition memory despite profound loss of recall memory. In the present study, rate of forgetting was measured in six amnesic subjects for both recall and recognition memory of verbal material. The data show that recall decayed significantly faster for the amnesic subjects than for controls, whereas the rate of forgetting for recognition memory was comparable in both groups. Dissociation between recall and recognition performance is a feature of the amnesic syndrome after cardiac arrest.
journal_name
Neurologyjournal_title
Neurologyauthors
Volpe BT,Holtzman JD,Hirst Wdoi
10.1212/wnl.36.3.408subject
Has Abstractpub_date
1986-03-01 00:00:00pages
408-11issue
3eissn
0028-3878issn
1526-632Xjournal_volume
36pub_type
杂志文章相关文献
NEUROLOGY文献大全abstract:BACKGROUND:Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease with complicated pathogenesis that poses challenges with respect to diagnosis and monitoring of disease progression. OBJECTIVES:To identify a biomarker panel that elucidates ALS disease pathogenesis, distinguishes patients with A...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000333251.36681.a5
更新日期:2009-01-06 00:00:00
abstract:BACKGROUND:The Babinski sign is a well-known sign of upper motor neuron dysfunction that is widely considered an essential element of a complete neurologic examination. Little is known about reliability and validity of this sign. A less well-known sign of upper motor neuron dysfunction, decreased speed of foot tapping,...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000180608.76190.10
更新日期:2005-10-25 00:00:00
abstract::We studied 25 patients within 6 hours of acute spinal cord injury using magnetically evoked cortical motor evoked potentials (MEPs). The subjects included 16 quadriplegics with cervical spine injuries and eight paraplegics. MEPs were recorded from abductor digiti minimi (ADM), biceps, flexor hallucis brevis, and tibia...
journal_title:Neurology
pub_type: 临床试验,杂志文章
doi:10.1212/wnl.45.2.303
更新日期:1995-02-01 00:00:00
abstract:BACKGROUND:The cytokine interferon beta (IFNbeta) is successfully used in the treatment of multiple sclerosis (MS), although there is a high degree of variability in the response. A common mechanism involved in the modulation of responsiveness to cytokines is represented by regulation of their receptor expression throu...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000327340.50284.8d
更新日期:2008-12-09 00:00:00
abstract:OBJECTIVE:To examine whether neuropathologic burden is associated with hearing impairment. METHODS:We studied 2,755 autopsied participants ≥55 years of age from the National Alzheimer's Coordinating Center database. Participants had at least 1 clinical evaluation at US National Institute on Aging-funded Alzheimer's Di...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000010575
更新日期:2020-09-22 00:00:00
abstract::Until 1995, treatment of strokes consisted exclusively of efforts to prevent recurrence. Proof that tissue plasminogen activator is useful for acute management is changing the approach to stroke patients. The development process has been difficult and the current treatment recommendations have been controversial. Rece...
journal_title:Neurology
pub_type: 杂志文章,评审
doi:10.1212/wnl.53.1.14
更新日期:1999-07-13 00:00:00
abstract:BACKGROUND:Bilateral absent N20 responses of median nerve somatosensory evoked potentials (SEPs) reliably predict poor prognosis after cardiac arrest. However, the studies supporting this fact were carried out before hypothermia was established as standard treatment. Recent evidence suggests that hypothermia treatment ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0b013e3181d5a631
更新日期:2010-03-23 00:00:00
abstract:BACKGROUND:TCH346 exerts antiapoptotic effects by binding to glyceraldehyde 3-phosphate dehydrogenase (GAPDH) and blocking the apoptotic pathway in which GAPDH is involved. Apoptosis is considered to be a key pathogenic mechanism in neurodegenerative diseases including ALS. METHODS:Patients were randomly assigned in a...
journal_title:Neurology
pub_type: 杂志文章,随机对照试验
doi:10.1212/01.wnl.0000269676.07319.09
更新日期:2007-08-21 00:00:00
abstract::We treated 64 emergency room patients with a primary vascular headache with dihydroergotamine (DHE), meperidine, or butorphanol. Post-treatment pain scores were lowest in the DHE group (p less than 0.01). Eight of 21 patients receiving DHE had greater than 90% reduction in pain compared with three of 19 patients recei...
journal_title:Neurology
pub_type: 临床试验,杂志文章
doi:10.1212/wnl.39.4.590
更新日期:1989-04-01 00:00:00
abstract::Large doses of phenytoin were administered on 159 occasions to 139 adult patients. Most patients had had more than three seizures or were in status epilepticus. Based on response to treatment, patients could be divided into two groups. Those with excellent response (recurrent seizures, 10%; mortality, 1%) included kno...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.29.11.1474
更新日期:1979-11-01 00:00:00
abstract::Zinc is essential for normal embryogenesis and may have particular importance for closure of the human neural tube. Compared to 258 controls, we found increased zinc content in umbilical cord serum in eight of nine newborn anencephalics (p less than 0.02) and three infants with spina bifida (p less than 0.001). Increa...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.34.4.443
更新日期:1984-04-01 00:00:00
abstract:OBJECTIVE:To investigate possible leptomeningeal contrast enhancement using postcontrast fluid-attenuated inversion recovery (FLAIR) MRI as an additional marker of inflammation in patients with multiple sclerosis (MS). METHODS:A cohort of 112 patients (73 women) with clinically definitive MS or a clinically isolated s...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000001286
更新日期:2015-02-24 00:00:00
abstract::We performed a 3-month, double-blind, placebo-controlled trial of 300 mg of gangliosides (Cronassial) in 40 outpatients with amyotrophic lateral sclerosis (ALS). We evaluated drug effect through physical examinations and symptom scales. Though this dosage had no major toxic effect, Cronassial treatment did not signifi...
journal_title:Neurology
pub_type: 临床试验,杂志文章
doi:10.1212/wnl.39.12.1635
更新日期:1989-12-01 00:00:00
abstract:BACKGROUND:Genetic studies of PD frequently rely on family history interviews (FHI), yet the accuracy of data obtained in this way is unclear. OBJECTIVE:To assess the interinformant reliability and validity of family history information on PD in first-degree relatives of PD cases and controls. METHODS:A structured FH...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000074784.35961.c0
更新日期:2003-07-08 00:00:00
abstract:OBJECTIVE:To assess the attitudes, knowledge, and practice patterns of US neurologists regarding migraine management relative to the US Headache Consortium Guidelines (the Guidelines). METHODS:Two samples of 600 neurologists each were selected from the American Academy of Neurology membership database. The first group...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.62.11.1926
更新日期:2004-06-08 00:00:00
abstract:OBJECTIVE:To determine the effect of interferon-beta-1b (IFNbeta-1b) treatment on total contrast-enhancing lesions (CEL), white matter lesion load (WMLL), and cerebral atrophy (CA) in patients with relapsing-remitting multiple sclerosis (RRMS) using serial monthly MRI. METHODS:An open-label baseline-vs-treatment cross...
journal_title:Neurology
pub_type: 临床试验,杂志文章
doi:10.1212/01.wnl.0000113765.75855.19
更新日期:2004-03-09 00:00:00
abstract::One hundred and eight multiple sclerosis (MS) patients and 108 matched controls were studied for antibody levels and cellular immune responses to several viruses. There were significant increases in the mean titers of complement fixation (CF) or hemagglutination inhibition (HI), and complement-mediated cytotoxicity (C...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.28.6.613
更新日期:1978-06-01 00:00:00
abstract::A 16-year-old male with a 9-year history of spontaneously arrested hydrocephalus was noted to have hydrosyringomyelia and increased intracranial pressure shortly after sustaining minor head trauma. His symptoms resolved completely following ventriculoperitoneal shunt replacement. Hydrosyringomyelia may occur in the se...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.38.4.652
更新日期:1988-04-01 00:00:00
abstract:BACKGROUND:The major histocompatibility complex (MHC) has been consistently associated with susceptibility to MS and the course of several other human autoimmune diseases. A putative association between the course and severity of MS and the MHC remains controversial. METHODS:DR and DQ genotyping by either restriction ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.51.3.742
更新日期:1998-09-01 00:00:00
abstract::We analyzed our experience with cough, exertional, and vascular sexual headaches, evaluated the interrelationships among them, and examined the possible symptomatic cases. Seventy-two patients consulted us because of headaches precipitated by coughing (n = 30), physical exercise (n = 28), or sexual excitement (n = 14)...
journal_title:Neurology
pub_type: 杂志文章,评审
doi:10.1212/wnl.46.6.1520
更新日期:1996-06-01 00:00:00
abstract::Three neuropathologists evaluated brain sections from 43 aged subjects for the presence of Alzheimer's disease. Moderate-to-substantial agreement was obtained. After discussion of disparate diagnoses, agreement was almost perfect for standardized and substantial for personal criteria. We conclude that reproducibility ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.42.2.329
更新日期:1992-02-01 00:00:00
abstract::Monocytes are recruited to active sites of multiple sclerosis (MS) demyelination and may promote local tissue injury by generating an inflammatory response, mediated in part by the production of toxic oxygen metabolites. Corticosteroids are frequently and effectively used to ameliorate MS exacerbations, despite inadeq...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.41.2_part_1.297
更新日期:1991-02-01 00:00:00
abstract::Using MRI, we investigated the morphology and blood-nerve barrier function of the peripheral nerve trunk in 10 patients with chronic inflammatory demyelinating polyneuropathy (CIDP). Eight patients had a focal demyelinative segment in the median or ulnar nerve trunk that was defined by conduction block or abnormal tem...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.48.4.874
更新日期:1997-04-01 00:00:00
abstract::Fifty patients underwent superficial temporal lobectomy for intractable temporal lobe epilepsy. Total cure rate was 52%, and significant improvement was achieved in 88%. Cytoarchitectural changes in gray and white tissue were analyzed under light microscopy. Neuronal dysgenesis was correlated with the duration of seiz...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.38.7.1041
更新日期:1988-07-01 00:00:00
abstract::People with AD have deficient contrast sensitivity and impaired face discrimination. The authors presented photographs of unfamiliar faces of three different sizes to enhance the low, middle, or high facial frequency information (cycles per face). Patients with AD demonstrated normal discrimination of small faces only...
journal_title:Neurology
pub_type: 临床试验,杂志文章
doi:10.1212/wnl.54.12.2316
更新日期:2000-06-27 00:00:00
abstract:OBJECTIVES:To investigate patient susceptibility to neuropsychiatric symptoms in the context of progression of more classic motor symptoms in amyotrophic lateral sclerosis (ALS) and to examine the impact of neuropsychiatric symptoms on survival. METHODS:The study cohort consisted of 219 patients with ALS (limb onset =...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000000023
更新日期:2014-01-14 00:00:00
abstract:OBJECTIVE:To discuss the indications and timing for resective surgery in patients with Sturge-Weber syndrome (SWS) and medication-resistant epilepsy. BACKGROUND:SWS that causes epilepsy severe enough to merit surgery is rare. Because of the variable natural history of the disease, it is difficult to establish clear-cu...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.55.10.1472
更新日期:2000-11-28 00:00:00
abstract:BACKGROUND:PD was associated with increased mortality before levodopa therapy became available. There have been conflicting reports of PD mortality in the modern era. OBJECTIVE:To assess current mortality rates in a large unselected population receiving treatment for parkinsonism (PKM) followed for up to 6 years. MET...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.57.12.2278
更新日期:2001-12-26 00:00:00
abstract:OBJECTIVE:Genetic variants ε2/ε4 within the APOE gene are established risk factors for lobar intracerebral hemorrhage (ICH). Published preliminary data suggest a potential role for APOE ε4 in risk of nonlobar ICH. We therefore investigated the role of APOE in recurrent nonlobar ICH, and sought to clarify whether effect...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000001790
更新日期:2015-07-28 00:00:00
abstract:OBJECTIVE:To determine the incidence and clinical effects of antibodies that develop during treatment with natalizumab. METHODS:In two randomized, double-blind, placebo-controlled studies (natalizumab safety and efficacy in relapsing remitting multiple sclerosis [MS, AFFIRM] and safety and efficacy of natalizumab in c...
journal_title:Neurology
pub_type: 杂志文章,随机对照试验
doi:10.1212/01.wnl.0000277457.17420.b5
更新日期:2007-10-02 00:00:00