Properties and distribution of glucocorticoid-binding sites in cytosol of the spinal cord.

abstract：:Structural and functional impairment of the skeletal system remains an important cause of morbidity and disability in patients with Cushing's syndrome (CS). Glucocorticoid (GC) excess inhibits bone formation and calcium absorption from the gut, increases bone resorption, and alters the secretion of gonadotropin and gr...

journal_title：Neuroendocrinology

authors： Kaltsas G,Makras P

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND/OBJECTIVE:Cortisol is thought to be involved in the pathophysiology of affective disorders. Less attention has been given to other neuroendocrine factors. The aim of the present study was to test the hypothesis that adrenocortical steroids aldosterone and cortisol show different dynamic changes in the course...

journal_title：Neuroendocrinology

authors： Izakova L,Hlavacova N,Segeda V,Kapsdorfer D,Morovicsova E,Jezova D

更新日期：2020-01-01 00:00:00

abstract：:The timing of the episodic secretion of luteinizing hormone (LH) in ovariectomized ewes was investigated with respect to an ultradian rest-activity cycle. Individual sheep were enclosed in a chamber where their physical activity was continuously monitored, and blood samples for LH analysis were collected at 5-min inte...

journal_title：Neuroendocrinology

authors： Rasmussen DD,Malven PV

更新日期：1981-06-01 00:00:00

abstract：BACKGROUND/AIMS:Stress exacerbates neuron loss in many CNS injuries via the actions of adrenal glucocorticoid (GC) hormones. For some injuries, this GC endangerment of neurons is accompanied by greater immune cell activation in the CNS, a surprising outcome given the potent immunosuppressive properties of GCs. METHODS...

journal_title：Neuroendocrinology

authors： Sorrells SF,Munhoz CD,Manley NC,Yen S,Sapolsky RM

更新日期：2014-01-01 00:00:00

abstract：:The effects of melatonin administration on thyroid physiology of female hamsters was investigated. A protocol of 25 micrograms given daily as subcutaneous injections late in the light period was found to inhibit blood levels of thyroxin (T4), triiodothyronine (T3) and thyrotropin (TSH). The free T4 index (FT4I) and th...

journal_title：Neuroendocrinology

authors： Vriend J,Richardson BA,Vaughan MK,Johnson LY,Reiter RJ

更新日期：1982-01-01 00:00:00

abstract：:Studies were undertaken to characterize the secretion of corticotropin-releasing factor (CRF) and arginine vasopressin (AVP) into the hypophysial-portal circulation of the conscious sheep. In addition, we examined the temporal relationship between the secretion of these two hypothalamic peptides and the secretion of t...

journal_title：Neuroendocrinology

authors： Engler D,Pham T,Fullerton MJ,Ooi G,Funder JW,Clarke IJ

更新日期：1989-04-01 00:00:00

abstract：:Patients with active acromegaly are frequently insulin resistant, glucose intolerant, and at risk for developing overt type 2 diabetes. At the same time, these patients have a relatively lean phenotype associated with mobilization and oxidation of free fatty acids. These features are reversed by curative surgical remo...

journal_title：Neuroendocrinology

authors： Dal J,List EO,Jørgensen JO,Berryman DE

更新日期：2016-01-01 00:00:00

abstract：INTRODUCTION:Several studies have suggested that diet, especially one enriched in microbiota-fermented fibers or fat, regulates behavior. The underlying mechanisms are currently unknown. We previously reported that certain macronutrients (fermentable fiber and protein) regulate energy homeostasis via the activation of ...

journal_title：Neuroendocrinology

authors： Sinet F,Soty M,Zemdegs J,Guiard B,Estrada J,Malleret G,Silva M,Mithieux G,Gautier-Stein A

更新日期：2021-01-11 00:00:00

abstract：:The effects of acute and chronic administration of a combination of lynestrenol-mestrenol, a widely employed contraceptive medication, on the dopaminergic system of the rat forebrain and striatum were investigated to better understand the biochemical basis of the neurological side-effects of steroid contraceptive drug...

journal_title：Neuroendocrinology

authors： Algeri S,Ponzio F,Dolfini E,Jori A

更新日期：1976-01-01 00:00:00

abstract：:The modulatory actions of ovarian steroids on the norepinephrine (NE) induced alterations in luteinizing hormone (LH) secretion were examined in male and female rats. Long-term (4 weeks) castrated male and female rats bearing chronic third-ventricle cannulae were implanted with intra-atrial catheters. Animals were ble...

journal_title：Neuroendocrinology

authors： Condon TP,Handa RJ,Gorski RA,Sawyer CH,Whitmoyer DI

更新日期：1986-01-01 00:00:00

abstract：:Estrogens are crucial determinants in the regulation of anterior pituitary function and maintenance of tissue homeostasis. Estrogen actions in this gland are exerted through both classical and non-classical mechanisms of action. This review summarizes the expression of classical α- and β-estrogen receptors and variant...

journal_title：Neuroendocrinology

authors： Zárate S,Seilicovich A

更新日期：2010-01-01 00:00:00

abstract：:To examine the role of excitatory amino acid neurotransmitters in the regulation of LH and FSH secretion in ovariectomized (ovx) adult rats treated with estradiol and progesterone, we measured the release rates of the excitatory amino acid neurotransmitters, glutamate and aspartate, as well as the neurally inactive am...

journal_title：Neuroendocrinology

authors： Ping L,Mahesh VB,Wiedmeier VT,Brann DW

更新日期：1994-04-01 00:00:00

abstract：:Gastric carcinoids are rare neuroendocrine tumors, usually classified as type I, if associated with atrophic body gastritis; type II, if associated with Zollinger-Ellison syndrome and multiple endocrine neoplasia type I, and type III, in the absence of any gastric pathology (sporadic tumors). The pathological features...

journal_title：Neuroendocrinology

authors： Delle Fave G,Capurso G,Annibale B,Panzuto F

更新日期：2004-01-01 00:00:00

abstract：:The effects of intracerebroventricularly (i.c.v.) injected interleukin-1 beta (IL-1 beta: 1, 2.5, 10, and 25 ng) were studied on plasma growth hormone (GH) and prolactin (PRL) concentrations in freely moving rats chronically implanted with i.c.v. cannulas and intracardial catheters. Significant changes in PRL secretio...

journal_title：Neuroendocrinology

authors： Payne LC,Obal F Jr,Opp MR,Krueger JM

更新日期：1992-07-01 00:00:00

abstract：:Phosphoinositol-specific phospholipase C enzymes (PLCs) are central to inositol lipid signalling pathways, facilitating intracellular Ca2+ release and protein kinase C activation. A sixth class of phosphoinositol-specific PLC with a novel domain structure, PLC-eta (PLCeta) has recently been discovered in mammals. Rece...

journal_title：Neuroendocrinology

authors： Stewart AJ,Morgan K,Farquharson C,Millar RP

更新日期：2007-01-01 00:00:00

abstract：:In goldfish the two native forms of gonadotropin-releasing hormone (GnRH), salmon GnRH (sGnRH) and chicken GnRH-II (cGnRH-II), stimulate both gonadotropin-II (GTH-II) and growth hormone (GH) release. Modifications of GnRH structure at positions 1, 2, 3, and 6 often result in an antagonist in goldfish, an observation w...

journal_title：Neuroendocrinology

authors： Murthy CK,Turner RJ,Wong AO,Rao PD,Rivier JE,Peter RE

更新日期：1994-06-01 00:00:00

abstract：:The c-fos protein is rapidly induced in hypothalamic magnocellular nuclei following hemorrhage. We used specific antibodies directed against c-fos and either vasopressin (AVP) or oxytocin (OT) neurophysin to investigate c-fos activation in individual AVP and OT neurons. AVP and OT neurons expressed c-fos in response t...

journal_title：Neuroendocrinology

authors： Roberts MM,Robinson AG,Fitzsimmons MD,Grant F,Lee WS,Hoffman GE

更新日期：1993-03-01 00:00:00

abstract：:Overt Cushing's syndrome is a rare disorder with an annual incidence of 2-3/million of which benign adrenal adenomas account for 0.6/million. The female:male ratio is 3:1. Preliminary data indicate a high proportion of subclinical Cushing's syndrome in certain risk populations such as patients with type 2 diabetes or ...

journal_title：Neuroendocrinology

authors： Steffensen C,Bak AM,Rubeck KZ,Jørgensen JO

更新日期：2010-01-01 00:00:00

abstract：:Histamine (HA) stimulates the release of the pro-opiomelanocortin (POMC)-derived peptides ACTH, beta-endorphin (beta-END), beta-lipotropin and alpha-melanocyte-stimulating hormone, and HA is involved in the mediation of the stress-induced release of these peptides. The effect of HA is indirect and may involve the hypo...

journal_title：Neuroendocrinology

authors： Kjaer A,Knigge U,Bach FW,Warberg J

更新日期：1992-09-01 00:00:00

abstract：:The presence of vasopressin (VP) in pars distalis of rats and pigs was investigated. Using radioimmunoassay and bioassay of VP, a substance with immunological and biological properties of this hormone was found. This substance was not detected in the adenohypophysis of rats with diabetes insipidus. A partial purificat...

journal_title：Neuroendocrinology

authors： Chateau M,Marchetti J,Burlet A,Boulange M

更新日期：1979-01-01 00:00:00

abstract：:The growth hormone secretagogue receptor subtype 1a (GHSR-1a) is involved in biological actions of ghrelin by triggering intracellular second messengers coupled to heterotrimeric G-protein complex involving Galpha(q/11). Adenosine is a partial agonist of the GHSR-1a, binding to a binding pocket distinct from the one d...

journal_title：Neuroendocrinology

authors： Carreira MC,Camiña JP,Smith RG,Casanueva FF

更新日期：2004-01-01 00:00:00

abstract：:An ultradian rhythm in adrenal secretion of corticosterone has been described in awake rats using intra-adrenal microdialysis. To determine the role of the autonomic innervation of the adrenal on the expression of the corticosterone rhythm, adrenal extracellular fluid was sampled by intra-adrenal microdialysis in inta...

journal_title：Neuroendocrinology

authors： Jasper MS,Engeland WC

更新日期：1994-02-01 00:00:00

abstract：:In order to characterize plasma prolactin (Prl) patterns during the estrous cycle and pseudopregnancy (PSP), I collected sequential blood samples between 8.00 and 19.00 h at 1-hour, 1.5-min or 1-min intervals from conscious, unrestrained female rats. During the afternoon of proestrus and estrus a single Prl surge was ...

journal_title：Neuroendocrinology

authors： Wiersma J

更新日期：1981-11-01 00:00:00

abstract：:Concentrations of luteinizing hormone (LH) and prolactin (Prl) in the serum of anestrous and cycling ewes were compared. The concentration of LH in serum and the frequency of episodic releases of LH were lower in anestrous than in cycling ewes. Concentrations of LH in serum rose as rapidly after ovariectomy of anestro...

journal_title：Neuroendocrinology

authors： Jackson GL,Davis SL

更新日期：1979-01-01 00:00:00

abstract：:Acetylcholinesterase (AChE) activity, and concentrations of monoamines, monoamine metabolites and oxytocin (OT) were measured in the cerebrospinal fluid (CSF) of sheep during late pregnancy, labour, parturition, vaginocervical stimulation, lamb separation and suckling. Concentrations of AChE, 4-hydroxy-3 methoxyphenyl...

journal_title：Neuroendocrinology

authors： Kendrick KM,Keverne EB,Baldwin BA,Sharman DF

更新日期：1986-01-01 00:00:00

abstract：:The expression of the mouse metallothionein-I (mMT) promoter/human growth hormone (hGH) fusion gene in transgenic mice leads to female sterility and major alterations in the function of the hypothalamic-adenohypophyseal system. These alterations include increases in median-eminence norepinephrine turnover and plasma L...

journal_title：Neuroendocrinology

authors： Steger RW,Bartke A,Parkening TA,Collins T,Buonomo FC,Tang KC,Wagner TE,Yun JS

更新日期：1991-04-01 00:00:00

abstract：:The properties of neuronal-type nicotinic acetylcholine receptors (nAChRs) present on the neuroendocrine cells of the porcine pars intermedia of the pituitary were studied in intact single cell using measurements of the free intracellular Ca2+ concentration ([Ca]i) with the calcium-sensitive dye fura 2. Local applicat...

journal_title：Neuroendocrinology

authors： Poisbeau P,Trouslard J,Feltz P,Schlichter R

更新日期：1994-10-01 00:00:00

abstract：:Previous research has shown an increase in hypothalamo-pituitary-adrenal axis activity following naloxone administration to morphine-dependent rats. In the present study, we investigated the adaptive changes in the noradrenaline (NA) and dopamine (DA) systems in the hypothalamic paraventricular nucleus (PVN) during mo...

journal_title：Neuroendocrinology

authors： Fuertes G,Laorden ML,Milanés MV

更新日期：2000-01-01 00:00:00

abstract：:Hypophyseal and ovarian receptors for the neurohormone LHRH (LHRH-R) have been measured in young (3-4 months), middle-aged (8-11 months), constant estrous (CE, 10-14 months) and pseudopregnant (PR, 16-18 months) rats in order to study whether changes in hypothalamic and/or peripheral LHRH-like peptide production might...

journal_title：Neuroendocrinology

authors： Marchetti B,Cioni M

更新日期：1988-09-01 00:00:00

abstract：:This study compares the processing of pro-opiomelanocortin (POMC) at two Lys-Lys cleavage sites, located in the carboxy-terminal domain of the precursor, one site marking the amino terminus of beta-melanocyte-stimulating hormone (beta-MSH) and the other in the carboxy-terminus of beta-endorphin (beta E). These compari...

journal_title：Neuroendocrinology

authors： Lin HL,Day NC,Ueda Y,Martin DK,Dixon JE,Seidah NG,Akil H

更新日期：1993-07-01 00:00:00