The clinical value of Haemoccult and Fecatwin in the detection of colorectal neoplasia in hospital and general practice patients.

Abstract:

:Four hundred and fifty asymptomatic general practice patients and 330 hospital inpatients had their stools tested for occult blood with the Haemoccult and Fecatwin methods. In general practice, 9/64 (14%) of patients with a positive result had a colonic neoplasm (three carcinomas, one Dukes' Stage A, two Dukes' Stage C, six adenomas) and in hospital 12/142 patients (8%) were found to have colonic tumours, (nine carcinomas, two Dukes' Stage A, two Dukes' Stage B, five Dukes' Stage C and three adenomas). The overall detection rates for colonic neoplasia were 2% in general practice and 3.4% in hospital. In 2 years of follow-up, none of the general practice patients have presented with colonic symptoms. Two hospital patients with colonic carcinomas produced negative tests with both methods. Out of the total of 21 colonic neoplasms, nine were detected by Fecatwin alone, but this trend in favour of the more sensitive test did not reach the 5% level of statistical significance. In contrast, the number of false positive results were significantly greater with Fecatwin than Haemoccult. From our data it would appear that the Fecatwin method warrants assessment in a full controlled trial of its value as a population screening test for colonic cancer.

journal_name

Postgrad Med J

authors

Barrison IG,Parkins RA

doi

10.1136/pgmj.61.718.701

subject

Has Abstract

pub_date

1985-08-01 00:00:00

pages

701-4

issue

718

eissn

0032-5473

issn

1469-0756

journal_volume

61

pub_type

临床试验,杂志文章
  • Autonomic neuropathy in African diabetic patients.

    abstract::To determine the prevalence and extent of autonomic neuropathy amongst Africans with insulin-dependent diabetes mellitus (IDDM), we investigated 50 such patients at our clinic. Mean age (+/- 1 s.d.) was 26 +/- 6 years, male:female ratio was equal (25M:25F) and duration of diabetes was 4.0 +/- 3.0 years. A battery of s...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.70.821.188

    authors: Tuch PS,Gill GV,Huddle KR

    更新日期:1994-03-01 00:00:00

  • Prospective study of acute gastrointestinal bleeding attributable to anti-inflammatory drug ingestion in the Yorkshire region of the United Kingdom.

    abstract:OBJECTIVE:To assess the general use of all non-steroidal anti-inflammatory drugs (NSAID) and their relation to upper gastrointestinal bleeding in view of National Institute for Clinical Excellence guidelines published in July 2001 in the UK. METHODS:Cross sectional study on all patients who were referred for endoscopy...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,多中心研究

    doi:10.1136/pgmj.2004.024885

    authors: Lim CH,Heatley RV

    更新日期:2005-04-01 00:00:00

  • Tissue plasminogen activator in the treatment of superior vena caval thrombosis associated with parenteral nutrition.

    abstract::Two patients, one of whom was pregnant, developed superior vena caval thrombosis while receiving central parenteral nutrition. They were successfully treated with recombinant tissue plasminogen activator (t-PA). ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.66.775.398

    authors: Barclay GR,Allen K,Pennington CR

    更新日期:1990-05-01 00:00:00

  • Bacterial calcification in infective endocarditis.

    abstract::The present report is the first description to our knowledge of a clinical case of bacterial calcification in human infective endocarditic vegetations. Partial calcification of bacteria within vegetations may be a further mechanism of bacterial protection from host defences and antibiotics. Similar calcification has r...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.65.767.665

    authors: Poller DN,Curry A,Ganguli LA,Routledge RC

    更新日期:1989-09-01 00:00:00

  • Potassium in the syndrome of inappropriate antidiuretic hormone secretion.

    abstract::Serum potassium concentration was normal (greater than or equal to 3.6 mmol/l) in 29 of 32 patients with the syndrome of inappropriate antidiuretic hormone excess (SIADH) associated with a bronchogenic carcinoma. In 11 of the patients there was no significant change in serum potassium concentration after correction of...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.55.648.721

    authors: Padfield PL,Morton JJ

    更新日期:1979-10-01 00:00:00

  • Intracoronary ultrasound.

    abstract::Although contrast angiography is important in the diagnosis and treatment of atherosclerotic disease, it does have limitations. Intracoronary ultrasound more accurately assesses the amount of atherosclerosis and has given us new insights into the pathophysiology of coronary plaque accumulation and remodelling. It also...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:10.1136/pgmj.74.874.468

    authors: Hammond C,Causer JP,Perry RA

    更新日期:1998-08-01 00:00:00

  • Neurosarcoidosis: unusual presentations and considerations for diagnosis and management.

    abstract:BACKGROUND:Sarcoidosis is a chronic, multisystem disease characterised by non-necrotising granulomatous inflammation of unknown aetiology. Most commonly, the lungs, lymph nodes, skin and eyes are affected in sarcoidosis; however, nervous system involvement occurs in approximately 5%-15% of cases. Any part of the nervou...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/postgradmedj-2016-134475

    authors: Radwan W,Lucke-Wold B,Robadi IA,Gyure K,Roberts T,Bhatia S

    更新日期:2017-07-01 00:00:00

  • Acyclovir treatment of herpes simplex encephalitis: experience in a district hospital.

    abstract::Herpes simplex encephalitis may be underdiagnosed in Britain. We report eight patients treated at one hospital over three years. Fever, impaired consciousness or focal neurological signs were seen in all patients at presentation but herpes simplex encephalitis was rarely considered as the initial diagnosis. The electr...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.63.746.1037

    authors: Gulliford MC,Chandrasekera CP,Cooper RA,Murphy RP

    更新日期:1987-12-01 00:00:00

  • Typhoid fever with severe pancytopenia.

    abstract::A patient suffering from typhoid fever with severe pancytopenia is presented. Bone marrow examination revealed extensive haemophagocytosis which possibly contributed to the pancytopenia. ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.73.855.41

    authors: Sood R,Roy S,Kaushik P

    更新日期:1997-01-01 00:00:00

  • The effect of nilvadipine on bloodflow in the dorsal pedis artery in type 2 diabetic patients--a study using duplex Doppler ultrasonography.

    abstract::The effects of nilvadipine on the peripheral circulation in the lower extremities using a duplex system of two-dimensional colour and pulse Doppler ultrasonography were studied in 32 patients with type 2 diabetes mellitus and mild essential hypertension. The patients (19 men and 13 women) were randomly divided into tr...

    journal_title:Postgraduate medical journal

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1136/pgmj.71.840.613

    authors: Sone H,Okuda Y,Mizutani M,Kawakami Y,Bannai C,Yamashita K

    更新日期:1995-10-01 00:00:00

  • Republished: obesity and colorectal cancer.

    abstract::Excess body weight, as defined by the body mass index (BMI), has been associated with several diseases and includes subjects who are overweight (BMI≥25-29.9 kg/m(2)) or obese (BMI≥30 kg/m(2)). Overweight and obesity constitute the fifth leading risk for overall mortality, accounting for at least 2.8 million adult deat...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/postgradmedj-2013-304701rep

    authors: Bardou M,Barkun AN,Martel M

    更新日期:2013-09-01 00:00:00

  • Recent development of ischaemic heart disease in sex difference.

    abstract::Despite a dramatic decline in mortality over the past years, coronary heart disease is the leading cause of death and disability in the world. At the same time, with the great improvement of medical science, there is a growing population of postmyocardial infarction, postrevascularisation and heart failure survivors. ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:10.1136/pgmj.2006.053140

    authors: Shu W,Lei W,Peng S

    更新日期:2007-04-01 00:00:00

  • Immobilization hypercalcaemia due to low bone formation and responding to intravenous sodium sulphate.

    abstract::A young man developed acute renal failure and hypercalcaemia following severe burns. The hypercalcaemia was initially controlled by haemodialysis, but it persisted after return of renal function. Plasma PTH was inappropriately elevated, but the nephrogenous cyclic adenosine monophosphate level was low; thus the PTH wa...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.62.727.395

    authors: Evans RA,Lawrence PJ,Thanakrishnan G,Hills E,Wong SY,Dunstan CR

    更新日期:1986-05-01 00:00:00

  • Relationship between body mass index and ischaemic stroke in Chinese elderly hypertensive patients.

    abstract:BACKGROUND:Despite obesity being a major risk factor for ischaemic stroke (IS), the association between body mass index (BMI) and IS in patients with hypertension remains uncertain. OBJECTIVE:To assess the association between BMI and IS among elderly hypertensive patients in China. METHODS AND RESULTS:We recruited 35...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/postgradmedj-2019-137457

    authors: Huang J,Liu L,Yu YL,Chen CL,Lo K,Huang YQ,Tang ST,Feng YQ

    更新日期:2020-03-27 00:00:00

  • Effect of nivazol in Nelson's syndrome.

    abstract::We report the use of nivazol in a patient with Nelson's syndrome. Nivazol was highly effective in reducing ACTH secretion but, contrary to reports of its use in other primates, in our patient nivazol did have systemic glucocorticoid effects. ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.64.749.220

    authors: Ball JA,Williams G,Yeo TH,Joplin GF

    更新日期:1988-03-01 00:00:00

  • Diurnal rhythms and clinical events in coronary artery disease.

    abstract::Patients with coronary atherosclerosis present with angina, myocardial infarction and sudden death, most often caused by atherosclerotic stenosis complicated by spasm and/or occlusive thrombosis. All of these events have been shown to exhibit similar diurnal rhythms, with a peak incidence in the morning after waking a...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:

    authors: Selwyn AP,Raby K,Vita JA,Ganz P,Yeung A

    更新日期:1991-01-01 00:00:00

  • Anabolic steroid induced hypogonadism treated with human chorionic gonadotropin.

    abstract::A case is presented of a young competitive body-builder who abused anabolic steroid drugs and developed profound symptomatic hypogonadotrophic hypogonadism. With the help of prescribed testosterone (Sustanon) he stopped taking anabolic drugs, and later stopped Sustanon also. Hypogonadism returned, but was successfully...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.74.867.45

    authors: Gill GV

    更新日期:1998-01-01 00:00:00

  • Effects of acetazolamide on cerebral blood flow and brain tissue oxygenation.

    abstract::Oral administration of 1 g of acetazolamide to 8 normal subjects studied at sea level and in normoxia caused an acute increase in cerebral blood flow (CBF). During the subsequent prolonged oral treatment with 1 g of acetazolamide daily, CBF returned to normal within 2 days. The alveolar CO2 tension decreased gradually...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.63.737.185

    authors: Lassen NA,Friberg L,Kastrup J,Rizzi D,Jensen JJ

    更新日期:1987-03-01 00:00:00

  • Adrenal insufficiency and bilateral adrenal enlargement: demonstration by computed tomography.

    abstract::A patient presented with fever, malaise and a staphylococcal wound infection occurring 3 weeks after severe haemorrhage from a lacerated brachial artery. There were no clinical features to suggest Addison's disease but abdominal computed tomography to exclude abdominal sepsis showed bilateral adrenal gland enlargement...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.61.715.435

    authors: Wheatley T,Gallagher S,Dixon AK

    更新日期:1985-05-01 00:00:00

  • Interaction studies and other investigations of the pharmacology of propofol ('Diprivan').

    abstract::The anaesthetic properties of propofol ('Diprivan') have been described previously. This report summarizes additional studies designed to investigate some aspects of the general pharmacology of propofol. Following recovery from anaesthesia with propofol there was no evidence of any central anticholinergic or anticonvu...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:

    authors: Glen JB,Hunter SC,Blackburn TP,Wood P

    更新日期:1985-01-01 00:00:00

  • The US residency programme--lessons for pre-registration house officer education in the UK?

    abstract::The 1994 NACT Wyeth-Ayerst Travelling Fellowship provided the opportunity to compare the education and welfare of pre-registration house officers in the UK with their nearest counterpart in the US residency system. Investment in all aspects of learning was impressive, as was the retention of the central role of the pa...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.71.835.273

    authors: Salter R

    更新日期:1995-05-01 00:00:00

  • Ulcerative colitis and sarcoidosis.

    abstract::Ulcerative colitis is not commonly associated with recognizable pulmonary disease and only four sporadic cases of sarcoidosis in association with ulcerative colitis have been previously reported. However, in a series of 680 patients with ulcerative colitis, pulmonary or extra-pulmonary sarcoidosis has at some stage be...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.62.727.341

    authors: Barr GD,Shale DJ,Jewell DP

    更新日期:1986-05-01 00:00:00

  • Finger clubbing and aspartylglucosamine excretion in a laxative-abusing patient.

    abstract::A young woman with a previous history of anorexia nervosa presented with severe finger clubbing. Urine samples intermittently contained significant amounts of aspartylglucosamine. Liver biopsy showed abnormal cytoplasmic inclusions in phagocytic cells. The patient was found to be abusing senna laxative. ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.56.662.862

    authors: Malmquist J,Ericsson B,Hultén-Nosslin MB,Jeppsson JO,Ljungberg O

    更新日期:1980-12-01 00:00:00

  • Is antibiotic resistance a problem? A practical guide for hospital clinicians.

    abstract::Antibiotic resistance is an important concern for patients, physicians, healthcare managers, and policymakers. Inappropriate antimicrobial prescribing fuels the evolution of resistance, while poor basic hygiene facilitates the spread of resistant microbes between patients and healthcare staff. The development of infec...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:10.1136/pgmj.2005.035113

    authors: Barlow G,Nathwani D

    更新日期:2005-11-01 00:00:00

  • Carcinoma of the pancreas presenting as mechanical obstruction of the colon.

    abstract::This purports to be the first recorded case of carcinoma of the pancreas presenting as a mechanical obstruction of the colon. The literature relating to some other rare modes of presentation is reviewed, and a comment made on the desirability of routine post-mortem studies. ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.57.663.66

    authors: Tresadern JC

    更新日期:1981-01-01 00:00:00

  • Cytomegalovirus infection in the neonate and its prevention.

    abstract::About 0.5% of infants are infected in utero with cytomegalovirus (CMV). As many as 20% become mentally retarded and a further substantial proportion suffer lesser degrees of brain damage. The need for a vaccine is greater than in the case of rubella. A live, tissue culture-adapted strain of CMV has been shown to produ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章,评审

    doi:10.1136/pgmj.53.624.588

    authors: Stern H

    更新日期:1977-10-01 00:00:00

  • Pediatric Emergency Care Applied Research Network head injury clinical prediction rules are reliable in practice.

    abstract:OBJECTIVE:The Pediatric Emergency Care Applied Research Network (PECARN) traumatic brain injury (TBI) age-based clinical prediction rules identify children at very low risk of a significant head injury who can safely avoid CT. Our goal was to independently validate these prediction rules. DESIGN:Cross-sectional study....

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/postgradmedj-2013-305004rep

    authors: Schonfeld D,Bressan S,Da Dalt L,Henien MN,Winnett JA,Nigrovic LE

    更新日期:2015-11-01 00:00:00

  • Staphylococcus aureus endocarditis presenting as acute scrotal pain.

    abstract::A previously healthy 17 year old boy had Staphylococcus aureus endocarditis presenting as acute scrotal pain. There was no trauma or evidence of scrotal or epididymal infection. The pain subsided after therapy for endocarditis was started. ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.63.741.585

    authors: Watanakunakorn C

    更新日期:1987-07-01 00:00:00

  • Tuberculous perforation of the small bowel.

    abstract::Small bowel perforation occurs in up to 2 percent of patients with abdominal tuberculous. Patients present with an acute abdomen. Resection of the diseased segment and 18 months treatment with anti-tuberculosis drugs is recommended. ...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.61.713.251

    authors: Aston NO,de Costa AM

    更新日期:1985-03-01 00:00:00

  • Multiple lymphomatous polyposis and the role of fine needle aspiration cytology.

    abstract::Multiple lymphomatous polyposis is an uncommon but distinctive form of gastrointestinal lymphoma. Clinical symptoms may closely resemble those of colorectal carcinoma and diagnostic confusion may result. The condition has a characteristic pathological appearance and immunophenotype which is important in allowing disti...

    journal_title:Postgraduate medical journal

    pub_type: 杂志文章

    doi:10.1136/pgmj.69.811.401

    authors: Carder PJ,Gouldesbrough DR

    更新日期:1993-05-01 00:00:00