Abstract:
:The rise in the concentration of LH in the serum that takes place in ovariectomized, estrogen-primed rats exposed to the odors from a cage with bedding soiled by a male rat was completely prevented by bilateral lesions destroying the ventral premammillary (PMv) nuclei. These results suggest that the pheromonal stimuli generate stimuli that course through a pathway which involves the PMv nuclei before they reach the hypothalamus. In addition, the chemosensory information is apparently transmitted centrally by an uncrossed pathway in view of the fact that removal of one vomeronasal organ combined with lesions of the contralateral PMv nucleus, but not of the ipsilateral nucleus, suppressed the release of LH in rats exposed to male odors. Since pheromonal stimuli are known to activate the accessory olfactory system, of which the medial (Me) amygdaloid nucleus and the bed nucleus of the stria terminalis (BNST) are parts, the effect of stimulating these nuclei in rats bearing lesions of the PMv nucleus was also investigated. Unilateral lesions of the PMv nucleus prevented the release of LH in ovariectomized, estrogen-primed rats and the advancement of LH surge in proestrous rats induced by electrochemical stimulation (anodic d.c. 100 microA/30 s) of the ipsilateral Me amygdaloid nucleus but not those induced by stimulation of the contralateral Me amygdaloid nucleus. Similar results were obtained stimulating the medial part of the BNST in proestrous rats. It is concluded that the impulses evoked by pheromonal stimuli inducing LH release in the rat are conveyed by an uncrossed pathway and relay in the PMv nucleus before they reach the medial basal hypothalamus.
journal_name
Neuroendocrinologyjournal_title
Neuroendocrinologyauthors
Beltramino C,Taleisnik Sdoi
10.1159/000124164subject
Has Abstractpub_date
1985-08-01 00:00:00pages
119-24issue
2eissn
0028-3835issn
1423-0194journal_volume
41pub_type
杂志文章abstract::Ghrelin is a 28-amino-acid gastric peptide that potently stimulates growth hormone (GH) secretion in vivo and in vitro. Ghrelin-expressing cells have been found in the oxyntic region of the stomach and in the arcuate nucleus of the hypothalamus. The aim of this work was to investigate the regional distribution and dev...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000068653
更新日期:2003-02-01 00:00:00
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journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000054657
更新日期:2001-06-01 00:00:00
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pub_type: 杂志文章
doi:10.1159/000123248
更新日期:1981-11-01 00:00:00
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journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000203644
更新日期:2009-01-01 00:00:00
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journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000064428
更新日期:2002-08-01 00:00:00
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journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000122974
更新日期:1980-01-01 00:00:00
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journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000124188
更新日期:1985-09-01 00:00:00
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journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000126131
更新日期:1992-03-01 00:00:00
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journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000123277
更新日期:1982-01-01 00:00:00
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journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000126119
更新日期:1992-02-01 00:00:00
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journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000122841
更新日期:1979-01-01 00:00:00
abstract::This study was designed to investigate the effects of penfluridol, a potent neuroleptic calmodulin inhibitor, on basal and secretagogue-stimulated secretion of thyroid-stimulating hormone (TSH), growth hormone (GH), and luteinizing hormone (LH). The drug had no effect on basal TSH or LH release, but decreased GH relea...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000123548
更新日期:1983-09-01 00:00:00
abstract::In addition to the magnocellular hypothalamic nuclei, arginine vasopressin (AVP)-containing neurons have also been identified in limbic structures, including the hippocampus and amygdala. In the present study, we compared the qualitative properties of the in vitro release of AVP from the dissected hypothalamus with th...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000126661
更新日期:1994-03-01 00:00:00
abstract::Corticotropin-releasing factor (CRF) is localized in fibers in the noradrenergic nucleus locus ceruleus (LC) and alters LC discharge characteristics when administered centrally. To determine whether CRF functions as a neurotransmitter in the LC during stress, the effects of hemodynamic stress on LC discharge were comp...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000125081
更新日期:1988-12-01 00:00:00
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journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000125118
更新日期:1989-02-01 00:00:00
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journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000509583
更新日期:2020-06-22 00:00:00
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journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000082735
更新日期:2004-01-01 00:00:00
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journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000126217
更新日期:1992-07-01 00:00:00
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journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000496106
更新日期:2019-01-01 00:00:00
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journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000127051
更新日期:1995-12-01 00:00:00
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journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000126418
更新日期:1993-04-01 00:00:00
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pub_type: 杂志文章
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更新日期:2014-01-01 00:00:00
abstract::A role for glutamate in signalling mechanisms in the mammalian pineal gland is suggested by the high concentration of the transmitter in pinealocytes and the expression of glutamate receptor subunits in the rat gland. A single type of glutamate binding site has been characterized in the rat and bovine pineal gland, pr...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000126847
更新日期:1995-03-01 00:00:00
abstract::The mammalian pineal gland appears to be a major endocrine component in the regulation of photoperiodic responses. The circadian pattern of secretion of the pineal hormone, melatonin, is regulated by the nervous system. Changes in photoperiod, acting via the nervous system, alter the temporal pattern of melatonin secr...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000123579
更新日期:1983-11-01 00:00:00
abstract::Prolactin (PRL) secretion in the female rat is regulated by an endogenous stimulatory rhythm (ESR), which is normally under the tonic inhibition of dopamine (DA). The ESR consists of a nocturnal (N) component which peaks at approximately 03.00 h, and a diurnal (D) component which peaks at approximately 17.00 h. This E...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000125694
更新日期:1991-01-01 00:00:00
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journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000505923
更新日期:2020-01-01 00:00:00
abstract::Distribution and properties of receptors for gonadotropin-releasing hormone (GnRH) were analyzed in the brain of adult male rats. Binding of the iodinated GnRH agonist Des-Gly10-(D-Ala6)-GnRH ethylamide was studied in hippocampus and anterior pituitary using three convergent approaches: quantitative autoradiography on...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000125053
更新日期:1988-11-01 00:00:00
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journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000125263
更新日期:1989-10-01 00:00:00
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journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000126372
更新日期:1993-01-01 00:00:00
abstract::The properties of neuronal-type nicotinic acetylcholine receptors (nAChRs) present on the neuroendocrine cells of the porcine pars intermedia of the pituitary were studied in intact single cell using measurements of the free intracellular Ca2+ concentration ([Ca]i) with the calcium-sensitive dye fura 2. Local applicat...
journal_title:Neuroendocrinology
pub_type: 杂志文章
doi:10.1159/000126772
更新日期:1994-10-01 00:00:00