Abstract：
:The role of dietary fat in human blood pressure control was studied among 84 middle-aged subjects (mainly couples) in two semirural communities in North Karelia, Finland. The families were randomly allocated into two groups that, after a baseline period of 2 weeks, changed their diet for a 12-week intervention period so that the proportion of energy derived from fats was similarly reduced in both groups, from 38 to 24%, but the polyunsaturated/saturated fatty acid (P/S) ratio was increased--from 0.2 to 0.9 in group I and to 0.4 in group II. After the intervention period, both groups switched back to their usual diet for a period of 5 weeks. During the intervention period, total serum cholesterol was reduced by 16% in group I and 14% in group II. Mean body weight and urinary sodium, potassium, calcium, and magnesium excretion changes were small or nonexistent. Mean systolic blood pressure decreased 4 mm Hg in group I (P less than 0.01) and 3 mm Hg in group II (P less than 0.01), and mean diastolic blood pressure decreased 5 mm Hg (P less than 0.001) and 4 mm Hg (P less than 0.01), respectively. The reductions were reversed during the switch-back period (P less than 0.01). These results confirm previous findings of the blood-pressure-reducing effect of a low-fat/high-P/S diet. Although a number of possible confounding factors can be ruled out, the dietary constituent accounting for the blood pressure change cannot be ascertained definitely. The results showed no significant further blood pressure reduction with more than a moderately increased P/S ratio when the saturated fat intake was markedly reduced.
journal_name
Prev Medjournal_title
Preventive medicineauthors
Puska P,Iacono JM,Nissinen A,Vartiainen E,Dougherty R,Pietinen P,Leino U,Uusitalo U,Kuusi T,Kostiainen Edoi
10.1016/0091-7435(85)90078-7subject
Has Abstract,Author List Incompletepub_date
1985-09-01 00:00:00pages
573-84issue
5eissn
0091-7435issn
1096-0260journal_volume
14pub_type
临床试验,杂志文章,随机对照试验abstract：:An international collaborative group examined the relation between asymptomatic hyperglycemia and coronary heart disease (CHD). After excluding clinically diagnosed diabetes and treated hypertensives, there were 48,912 men aged 35-64 in the study population. Post-load circulating glucose correlated with age, relative ...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/0091-7435(83)90173-1
更新日期：1983-01-01 00:00:00
abstract：BACKGROUND:Exposure to tobacco and alcohol advertising has been associated with adolescent substance use. However, it is not clear whether favorable reactions to advertising are an antecedent to or a consequence of substance use. This study investigated relationships between adolescents' levels of susceptibility to sub...
journal_title：Preventive medicine
pub_type： 杂志文章
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更新日期：1995-09-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/j.ypmed.2004.01.017
更新日期：2004-06-01 00:00:00
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journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1006/pmed.1993.1018
更新日期：1993-03-01 00:00:00
abstract：:Studies of adult nutrition education and counseling for weight reduction, diabetes, cancer, low-fat diets, sodium-restricted diets, and renal diets are reviewed and synthesized. Nutrition education consists of three phases: assessment or problem diagnosis, intervention, and evaluation and monitoring. This article exam...
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pub_type： 杂志文章,评审
doi：10.1016/0091-7435(85)90069-6
更新日期：1985-11-01 00:00:00
abstract：BACKGROUND:Factors associated with participation in breast and cervix cancer screening among elderly black women of low socioeconomic status were determined. METHODS:Data from a baseline cross-sectional random survey were used together with data on whether screening was subsequently completed or refused. The subjects ...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1006/pmed.1993.1002
更新日期：1993-01-01 00:00:00
abstract：BACKGROUND:Studies of the relationship between dietary fat intake and serum lipids in young children have yielded inconclusive results. We studied this relationship in 108 Hispanic children ages 4-5 years. METHODS:Four 24-hr recalls approximately 3 months apart and two Willett semiquantitative food frequency questionn...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/0091-7435(91)90023-w
更新日期：1991-03-01 00:00:00
abstract：BACKGROUND:Walking is a widely used approach to increase physical activity levels in obese patients. In this paper, we investigate the precision and accuracy of an ankle-worn dual-axis accelerometer (Stepwatch) and investigate its potential application as a predictor of energy expenditure. METHODS:Twenty healthy subje...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2005.07.006
更新日期：2005-09-01 00:00:00
abstract：:We summarize here the evidence from the 1960s and 1970s of exceptionally high risk of cardiovascular disease (CVD) in Finland. In parallel with voluntary and governmental prevention programs, the level of risk factors and CVD attack rates have shown dramatic improvement in the past 25 years, but the decline has slowed...
journal_title：Preventive medicine
pub_type： 杂志文章,评审
doi：10.1006/pmed.1999.0403
更新日期：1999-12-01 00:00:00
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journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2017.11.005
更新日期：2018-01-01 00:00:00
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journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2009.12.007
更新日期：2010-03-01 00:00:00
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journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2017.02.010
更新日期：2017-06-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/j.ypmed.2021.106423
更新日期：2021-01-10 00:00:00
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journal_title：Preventive medicine
pub_type： 临床试验,杂志文章
doi：10.1016/j.ypmed.2007.09.007
更新日期：2008-03-01 00:00:00
abstract：:Extracurricular sport has been a valued educational investment to promote both physical and mental health in children and adolescents. Few longitudinal studies have tested whether extracurricular sport is associated with inattentive/hyperactive symptoms. Using a prospective-longitudinal birth cohort of 758 girls and 7...
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更新日期：2020-12-01 00:00:00
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journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2011.12.002
更新日期：2012-02-01 00:00:00
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pub_type： 杂志文章,评审
doi：10.1016/j.ypmed.2008.11.014
更新日期：2009-02-01 00:00:00
abstract：BACKGROUND:Nutrition education tailored to individual characteristics of people might be more effective than general nutrition education. Nowadays, the use of computers makes individualized feedback available for larger groups. METHODS:The impact of tailored nutrition information on changes in fat, vegetable, and frui...
journal_title：Preventive medicine
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1006/pmed.1996.0052
更新日期：1996-05-01 00:00:00
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journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1006/pmed.1993.1051
更新日期：1993-07-01 00:00:00
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journal_title：Preventive medicine
pub_type： 杂志文章,meta分析
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更新日期：2019-06-01 00:00:00
abstract：BACKGROUND:Underutilization of breast and cervical cancer screening has been observed in many ethnic groups and underserved populations. Effective community-based interventions are needed to eliminate disparities in screening rates and thus to improve prospects for survival. METHODS:The Breast and Cervical Cancer Inte...
journal_title：Preventive medicine
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1006/pmed.2001.0871
更新日期：2001-09-01 00:00:00
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doi：10.1016/j.ypmed.2020.106260
更新日期：2020-12-01 00:00:00
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journal_title：Preventive medicine
pub_type： 杂志文章,多中心研究
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更新日期：1999-08-01 00:00:00
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journal_title：Preventive medicine
pub_type： 临床试验,杂志文章,随机对照试验
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更新日期：2004-11-01 00:00:00
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journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1006/pmed.1997.0194
更新日期：1997-09-01 00:00:00
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journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1006/pmed.2001.0880
更新日期：2001-10-01 00:00:00
abstract：BACKGROUND:A large portion of the elderly population of the United States fails to receive an annual influenza vaccination. Minorities may receive disproportionately fewer vaccinations. The objectives of this study were to (a) estimate the levels of influenza vaccination among noninstitutionalized, U.S. citizens, 65 ye...
journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1006/pmed.2001.0983
更新日期：2002-02-01 00:00:00
abstract：BACKGROUND:Increasing regular physical activity in adults at elevated risk of cardiovascular disease is an important target for preventive medicine. This study evaluated demographic, social and cognitive predictors of self-reported changes in physical activity after 4 and 12 months in a randomized trial of behavioral c...
journal_title：Preventive medicine
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1006/pmed.2000.0688
更新日期：2000-08-01 00:00:00
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journal_title：Preventive medicine
pub_type： 杂志文章
doi：10.1016/j.ypmed.2004.07.017
更新日期：2005-04-01 00:00:00
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journal_title：Preventive medicine
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/j.ypmed.2004.04.017
更新日期：2004-12-01 00:00:00
