Abstract：
:Sucrose gradient analysis of DNA isolated from detergent-pronase lysates of adult flies has been used to look for ribosomal genes not integrated into the DNA of the chromosome in genotypes containing various combinations of inversions having breakpoints in the proximal heterochromatin of the X chromosome. Unintegrated genes are found in females heterozygous for inversions which have one breakpoint between the nucleolus organizer and the centromere. Homozygotes and males do not have unintegrated genes. The results suggest that unintegrated ribosomal genes result from an interaction between homologues having different arrangements of the proximal heterochromatin. In addition, data from a series of stocks carrying duplications of the X heterochromatin provide independent evidence for the size of the DNA on our gradients.
journal_name
Celljournal_title
Cellauthors
Harford AG,Zuchowski CIdoi
10.1016/0092-8674(77)90056-3subject
Has Abstractpub_date
1977-06-01 00:00:00pages
389-94issue
2eissn
0092-8674issn
1097-4172pii
0092-8674(77)90056-3journal_volume
11pub_type
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