Abstract:
:Freeze-dried venous interposition allografts with an internal diameter of 1.0 mm and a length of 1.0 cm were placed into the femoral arteries of 17 Sprague-Dawley albino male rats in order to investigate patency and host tissue response. The immediate patency rate was 88%. The epigastric island flap was monitored as a sign of patency in the early postoperative period (defined as 1 to 3 days). Twelve of the 17 subjects were observed for 2 months, at which point 66% (8/12) remained patent. There were two aneurysmal dilatations. Histopathological studies and transmission electron microscopy demonstrated that freeze-dried veins undergo complete remodeling in vivo by a normal reparative process and that they do not induce a cellular immune response in the host.
journal_name
Microsurgeryjournal_title
Microsurgeryauthors
Pratt MF,Schneider J,Norris MSdoi
10.1002/micr.1920060405subject
Has Abstractpub_date
1985-01-01 00:00:00pages
211-8issue
4eissn
0738-1085issn
1098-2752journal_volume
6pub_type
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