Morphology and physical properties of Staphylococcus bacteriophage P11-M15.

abstract：:Live-attenuated vesicular stomatitis virus (VSV) vectors expressing foreign antigens induce potent immune responses and protect against viral diseases in animal models. Highly attenuated (VSV-CT1) or single-cycle VSV (VSVDeltaG) vectors induce immune responses lower than those generated by attenuated wild-type VSV vec...

journal_title：Journal of virology

authors： Simon ID,Publicover J,Rose JK

更新日期：2007-02-01 00:00:00

abstract：:Rodent fibroblasts infected with the ts371 Kirsten murine sarcoma virus (KiMuSV) are temperature sensitive for the maintenance of transformation because of the production of an abnormal p21 protein. We cloned the ts371 KiMuSV provirus from the genome of a conditionally transformed nonproducer cell line, ts371 KiMuSV N...

journal_title：Journal of virology

authors： Stein RB,Tai JY,Scolnick EM

更新日期：1986-11-01 00:00:00

abstract：:H9N2 avian influenza virus (AIV) has an extended host range, but the molecular basis underlying H9N2 AIV transmission to mammals remains unclear. We isolated more than 900 H9N2 AIVs in our 3-year surveillance in live bird markets in China from 2009 to 2012. Thirty-seven representative isolates were selected for furthe...

journal_title：Journal of virology

authors： Teng Q,Xu D,Shen W,Liu Q,Rong G,Li X,Yan L,Yang J,Chen H,Yu H,Ma W,Li Z

更新日期：2016-10-14 00:00:00

abstract：:The human T-cell leukemia virus type 1 (HTLV-1) transforming protein, Tax, is a potent transactivator of both viral and cellular gene expression. The ability of Tax to transform cells is believed to depend on its transactivation of cellular-growth-regulatory genes. Expression of proliferating cell nuclear antigen (PCN...

journal_title：Journal of virology

authors： Ressler S,Morris GF,Marriott SJ

更新日期：1997-02-01 00:00:00

abstract：:A poliovirus-specific polyuridylic acid [poly(U)] polymerase that copies a polyadenylic acid template complexed to an oligouridylic acid primer was isolated from the membrane fraction of infected HeLa cells and was found to sediment at 4 to 5S on a linear 5 to 20% glycerol gradient. When the poly(U) polymerase was iso...

journal_title：Journal of virology

authors： Flanegan JB,Baltimore D

更新日期：1979-01-01 00:00:00

abstract：:Canine distemper virus attachment (hemagglutinin [H] equivalent) and fusion (F) antigens were purified by affinity chromatography with monoclonal antibodies. The purified antigens were used to immunize groups of three dogs. Radioimmune precipitation assays with sera from these animals showed that the F antigen prepara...

journal_title：Journal of virology

authors： Norrby E,Utter G,Orvell C,Appel MJ

更新日期：1986-05-01 00:00:00

abstract：:The existence of novel endogenous retrovirus elements in the chicken genome, designated EAV-HP, with close sequence identity to the env gene of avian leukosis virus (ALV) subgroup J has been reported (L. M. Smith, A. A. Toye, K. Howes, N. Bumstead, L. N. Payne, and K. Venugopal, J. Gen. Virol. 80:261-268, 1999). To re...

journal_title：Journal of virology

authors： Sacco MA,Flannery DM,Howes K,Venugopal K

更新日期：2000-02-01 00:00:00

abstract：:Using synthetic peptides, we characterized the B-lymphocyte (antibody) and T-lymphocyte (proliferation) responses to an immunodominant epitope of human immunodeficiency virus type 1 (HIV-1) located near the amino-terminal end of the transmembrane glycoprotein (env amino acids 598 to 609). Both immunoglobulin M (IgM) a...

journal_title：Journal of virology

authors： Schrier RD,Gnann JW Jr,Langlois AJ,Shriver K,Nelson JA,Oldstone MB

更新日期：1988-08-01 00:00:00

abstract：:Virus-specific RNA synthesized in monkey cells after infection by both wild-type simian virus 40 (SV40) and the early SV40 temperature-sensitive mutant tsA58 has been analyzed. The fraction of SV40-specific RNA increased throughout infection with either wild-type SV40 or with tsA58 in direct proportion to the accumula...

journal_title：Journal of virology

authors： Khoury G,May E

更新日期：1977-07-01 00:00:00

abstract：:The gene encoding glycoprotein B (gB) of murine cytomegalovirus (MCMV) strain Smith was identified, sequenced, and expressed by recombinant vaccinia virus. The gB gene was found adjacent to the polymerase gene, as it is in the genome of human cytomegalovirus (HCMV). The open reading frame consists of 2,784 nucleotides...

journal_title：Journal of virology

authors： Rapp M,Messerle M,Bühler B,Tannheimer M,Keil GM,Koszinowski UH

更新日期：1992-07-01 00:00:00

abstract：:Cowpox virus, in contrast to vaccinia virus, can multiply in Chinese hamster ovary cells. To study the genetic basis for this difference in host range, recombinants between vaccinia and cowpox viruses were isolated and their DNA restriction patterns were examined. The ability to multiply in Chinese hamster ovary cells...

journal_title：Journal of virology

authors： Spehner D,Gillard S,Drillien R,Kirn A

更新日期：1988-04-01 00:00:00

abstract：:We have evaluated the physical state and infectious nature of Kaposi's sarcoma-associated herpesvirus (KSHV) in the saliva of nine persons with past or current Kaposi's sarcoma (KS). KSHV DNA in saliva had the physical characteristics of DNA present in virions. Inoculation of 293 cells with cell-free saliva fluid resu...

journal_title：Journal of virology

authors： Vieira J,Huang ML,Koelle DM,Corey L

更新日期：1997-09-01 00:00:00

abstract：:The second of three short upstream open reading frames (uORF2) in the transcript leader of the human cytomegalovirus gp48 (gpUL4) virion glycoprotein gene inhibits downstream translation approximately 10-fold. Remarkably, this inhibition depends on the amino acid coding information of uORF2. In the current studies we ...

journal_title：Journal of virology

authors： Cao J,Geballe AP

更新日期：1995-02-01 00:00:00

abstract：:The virion host shutoff protein (vhs) of herpes simplex virus (HSV) triggers global shutoff of host protein synthesis and accelerated mRNA turnover during virus infection and induces endoribonucleolytic cleavage of exogenous RNA substrates when it is produced in a rabbit reticulocyte (RRL) in vitro translation system....

journal_title：Journal of virology

authors： Lu P,Jones FE,Saffran HA,Smiley JR

更新日期：2001-02-01 00:00:00

abstract：:The neutralizing activities of polyclonal antibodies and monoclonal antibodies (MAbs) obtained by immunization of mice with L1 virus-like particles (VLPs) were investigated by using pseudovirion infectivity assays for human papillomavirus type 16 (HPV-16), HPV-31, HPV-33, HPV-45, HPV-58, and HPV-59 to obtain a better ...

journal_title：Journal of virology

authors： Combita AL,Touzé A,Bousarghin L,Christensen ND,Coursaget P

更新日期：2002-07-01 00:00:00

abstract：:Human bocavirus (HBoV) is a newly discovered parvovirus associated with acute respiratory tract illness (ARTI) and gastrointestinal illness. No previous reports indicated the presence of HBoV infection in Jiangsu Province, China. Here we report three complete genomic sequences of HBoV strains from children with gastro...

journal_title：Journal of virology

authors： Wang X,Zhang X,Tian H,Ling F,Yu M,Sun G,Yang S,Shen Q,Wang Y,Shao S,Zhang W

更新日期：2012-12-01 00:00:00

abstract：:The bacteriophage T4 unf gene, known to be involved in the arrest of transcription from cytosine-containing DNA, is unessential except in Escherichia coli strains containing plasmid pR386. Comparative genetic and biochemical analyses of parameters of unf+ and unf- phage growth in host cells isogenic except for the pre...

journal_title：Journal of virology

authors： Herman RE,Snustad DP

更新日期：1985-02-01 00:00:00

abstract：:It is shown that the plasmid prophage P1 can be displaced by a superinfecting P1 phage in Escherichia coli recA(P1) lysogens. Six widely separated phage markers were used to distinguish between residual recombination and total substitution. It is further shown that superinfection of recA lysogens can lead to loss of b...

journal_title：Journal of virology

authors： Meurs E,D'Ari R

更新日期：1979-08-01 00:00:00

abstract：:Epstein-Barr virus (EBV) nuclear antigen 2 (EBNA-2) is a key determinant in the EBV-driven B-cell growth transformation process. By activating an array of viral and cellular target genes, EBNA-2 initiates a cascade of events which ultimately cause cell cycle entry and the proliferation of the infected B cell. In order...

journal_title：Journal of virology

authors： Maier S,Staffler G,Hartmann A,Höck J,Henning K,Grabusic K,Mailhammer R,Hoffmann R,Wilmanns M,Lang R,Mages J,Kempkes B

更新日期：2006-10-01 00:00:00

abstract：:The interaction of the human immunodeficiency virus type 1 (HIV-1) nucleoprotein complex with the cell nuclear import machinery is necessary for viral replication in macrophages and for the establishment of infection in quiescent T lymphocytes. The karyophilic properties of two viral proteins, matrix (MA) and Vpr, are...

journal_title：Journal of virology

authors： Gallay P,Stitt V,Mundy C,Oettinger M,Trono D

更新日期：1996-02-01 00:00:00

abstract：:Replicase gene expression by the human coronavirus 229E involves the synthesis of two large polyproteins, pp1a and pp1ab. Experimental evidence suggests that these precursor molecules are subject to extensive proteolytic processing. In this study, we show that a chymotrypsin-like enzyme, the virus-encoded 3C-like prot...

journal_title：Journal of virology

authors： Ziebuhr J,Siddell SG

更新日期：1999-01-01 00:00:00

abstract：:Further advances are required in understanding protection from AIDS by T-cell immunity. We analyzed a set of multigenic simian/human immunodeficiency virus (SHIV) DNA and fowlpox virus priming and boosting vaccines for immunogenicity and protective efficacy in outbred pigtail macaques. The number of vaccinations requi...

journal_title：Journal of virology

authors： Dale CJ,De Rose R,Stratov I,Chea S,Montefiori DC,Thomson S,Ramshaw IA,Coupar BE,Boyle DB,Law M,Kent SJ

更新日期：2004-12-01 00:00:00

abstract：:Upon immunization and restimulation with tumors induced by the endogenous AKR/Gross murine leukemia virus (MuLV), C57BL/6 mice generate vigorous H-2K(b)-restricted cytotoxic T-lymphocyte (CTL) responses to a determinant (KSPWFTTL) derived from the p15E transmembrane portion of the viral envelope glycoprotein. By contr...

journal_title：Journal of virology

authors： Kim V,Yewdell JW,Green WR

更新日期：2000-04-01 00:00:00

abstract：:Due to the biological significance of the carbohydrate component of the human immunodeficiency virus type 1 (HIV-1) glycoproteins in viral pathogenesis, the glycosylation step constitutes an attractive target for anti-HIV therapy. Cyanovirin N (CV-N), which specifically targets the high-mannose (HM) glycans on gp120, ...

journal_title：Journal of virology

authors： Witvrouw M,Fikkert V,Hantson A,Pannecouque C,O'keefe BR,McMahon J,Stamatatos L,de Clercq E,Bolmstedt A

更新日期：2005-06-01 00:00:00

abstract：:Infectious hematopoietic necrosis virus (IHNV) is a rhabdovirus that produces an acute, lethal infection in rainbow trout (Oncorhynchus mykiss). Fish that survive infection cease to produce detectable infectious virus at approximately 46 days after infection, yet there is evidence that survivor fish continue to harbor...

journal_title：Journal of virology

authors： Kim CH,Dummer DM,Chiou PP,Leong JA

更新日期：1999-01-01 00:00:00

abstract：:Host-virus interactions control disease progression in human immunodeficiency virus-infected human beings and in nonhuman primates infected with simian or simian/human immunodeficiency viruses (SHIV). These interactions evolve rapidly during acute infection and are key to the mechanisms of viral persistence and AIDS. ...

journal_title：Journal of virology

authors： Wallace M,Waterman PM,Mitchen JL,Djavani M,Brown C,Trivedi P,Horejsh D,Dykhuizen M,Kitabwalla M,Pauza CD

更新日期：1999-12-01 00:00:00

abstract：:Nonconservative substitutions for Tyr-115 in the reverse transcriptase (RT) of human immunodeficiency virus type 1 (HIV-1) lead to enzymes displaying lower affinity for deoxynucleoside triphosphates (dNTPs) (A. M. Martín-Hernández, E. Domingo, and L. Menéndez-Arias, EMBO J. 15:4434-4442, 1996). Several mutations at th...

journal_title：Journal of virology

authors： Olivares I,Sánchez-Merino V,Martínez MA,Domingo E,López-Galíndez C,Menéndez-Arias L

更新日期：1999-08-01 00:00:00

abstract：:Duck embryo fibroblast (DEF) and chicken embryo fibroblast (CEF) cultures infected with Marek's disease virus were studied by combined fluorescent antibody and electron microscopy techniques. In both DEF and CEF cultures, cells containing immunofluorescent (IF) antigen also contained herpesvirus particles; conversely,...

journal_title：Journal of virology

authors： Nazerian K,Purchase HG

更新日期：1970-01-01 00:00:00

abstract：:During paramyxovirus entry into a host cell, receptor engagement by a specialized binding protein triggers conformational changes in the adjacent fusion protein (F), leading to fusion between the viral and cell membranes. According to the existing paradigm of paramyxovirus membrane fusion, the initial activation of F ...

journal_title：Journal of virology

authors： Porotto M,Devito I,Palmer SG,Jurgens EM,Yee JL,Yokoyama CC,Pessi A,Moscona A

更新日期：2011-12-01 00:00:00

abstract：:High-risk human papillomaviruses (HPVs), including HPV-16 and HPV-18, are the causative agents of cervical carcinomas and are linked to several other tumors of the anogenital and oropharyngeal regions. The majority of HPV-induced tumors contain integrated copies of the normally episomal HPV genome that invariably reta...

journal_title：Journal of virology

authors： Kennedy EM,Kornepati AV,Goldstein M,Bogerd HP,Poling BC,Whisnant AW,Kastan MB,Cullen BR

更新日期：2014-10-01 00:00:00