Clinical evaluation of intravenous nitroglycerin for neurosurgery.

Abstract:

:Moment-to-moment control of blood pressure is important in the management of the neurosurgical patient. The ideal agent to control blood pressure or induce hypotension should be non-toxic, maintain cerebrovascular autoregulation, and not alter cardiac output or change intracranial pressure. Intravenous nitroglycerin has been used to control blood pressure in 54 neurosurgical cases. This agent produces a rapid, controllable, but not precipitous fall in blood pressure without rebound, is non-toxic, may not alter cerebrovascular autoregulation, and does not raise intracranial pressure. Our clinical experience with intravenous nitroglycerin indicates that it has an important role as a hypotensive agent for the neurosurgical patient.

journal_name

J Neurosurg

journal_title

Journal of neurosurgery

authors

Chestnut JS,Albin MS,Gonzalez-Abola E,Newfield P,Maroon JC

doi

10.3171/jns.1978.48.5.0704

subject

Has Abstract

pub_date

1978-05-01 00:00:00

pages

704-11

issue

5

eissn

0022-3085

issn

1933-0693

journal_volume

48

pub_type

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