Changes in deoxyribonucleic acid synthesis regulation in Chinese hamster cells infected with simian virus 40.

abstract：:Initiation of the Epstein-Barr virus (EBV) lytic cycle is dependent on expression of the viral transactivator Zta, which is encoded by the BZLF1 gene. Described here is an initial mapping of the regions of Zta involved in activating transcription. The data indicate that the amino-terminal 153 amino acids of Zta are im...

journal_title：Journal of virology

authors： Flemington EK,Borras AM,Lytle JP,Speck SH

更新日期：1992-02-01 00:00:00

abstract：:Adaptation of field isolates of foot-and-mouth disease virus (FMDV) to grow in cells in culture can result in changes in viral properties that include acquisition of the ability to bind to cell surface heparan sulfate (HS). After 13 passages on BHK cells to produce a vaccine, a Cathay topotype isolate of FMDV serotype...

journal_title：Journal of virology

authors： Zhao Q,Pacheco JM,Mason PW

更新日期：2003-03-01 00:00:00

abstract：:To examine the mode of transmission of BK polyomavirus (BKV), urine samples were collected from Japanese-Americans in Los Angeles and from other southern Californians. Subtype I was the main subtype found in samples from both groups. The subtype I subgroup Ib-2, which is predominant in Europe, was the primary subgroup...

journal_title：Journal of virology

authors： Yogo Y,Zhong S,Suzuki M,Shibuya A,Kitamura T

更新日期：2007-12-01 00:00:00

abstract：:A human cytomegalovirus (CMV) UL54 pol exonuclease domain II mutation, D413A, found in a clinical specimen, conferred ganciclovir (GCV) and cidofovir resistance but not foscarnet resistance when incorporated into laboratory strain T2294. After several passages without drug, mutation was observed in five of eight plaqu...

journal_title：Journal of virology

authors： Chou S,Marousek GI

更新日期：2008-01-01 00:00:00

abstract：:Cytomegalovirus (CMV) disease after bone marrow (BM) transplantation is often associated with BM graft failure. There are two possible reasons for such a correlation. First, a poor hematopoietic reconstitution of unrelated etiology could promote the progression of CMV infection by the lack of immune control. Alternati...

journal_title：Journal of virology

authors： Steffens HP,Podlech J,Kurz S,Angele P,Dreis D,Reddehase MJ

更新日期：1998-06-01 00:00:00

abstract：:In clinical trials, HIV-1 broadly neutralizing antibodies (bnAbs) effectively lower plasma viremia and delay virus reemergence. The presence of less neutralization-susceptible strains prior to treatment decreases the efficacy of these antibody-based treatments, but neutralization sensitivity often cannot be predicted ...

journal_title：Journal of virology

authors： Registre L,Moreau Y,Ataca ST,Pulukuri S,Henrich TJ,Lin N,Sagar M

更新日期：2020-01-06 00:00:00

abstract：:At least four members of the integrin family of receptors, alphaVbeta1, alphaVbeta3, alphaVbeta6, and alphaVbeta8, have been identified as receptors for foot-and-mouth disease virus (FMDV) in vitro. Our investigators have recently shown that the efficiency of receptor usage appears to be related to the viral serotype ...

journal_title：Journal of virology

authors： Duque H,LaRocco M,Golde WT,Baxt B

更新日期：2004-09-01 00:00:00

abstract：:Our study was designed to investigate the nature of an antigen-specific suppressor factor generated by antigen-stimulated herpes simplex virus (HSV)-immune splenocytes. Factor SF-200, a 90,000- to 100,000-dalton fraction obtained after Sephacryl gel filtration, suppressed the generation of HSV-specific cytotoxic T-lym...

journal_title：Journal of virology

authors： Horohov DW,Wyckoff JH 3rd,Moore RN,Rouse BT

更新日期：1986-05-01 00:00:00

abstract：UNLABELLED:The role of NF-κB in influenza A virus (IAV) infection does not reveal a coherent picture, as pro- and also antiviral functions of this transcription factor have been described. To address this issue, we used clustered regularly interspaced short palindromic repeat with Cas9 (CRISPR-Cas9)-mediated genome eng...

journal_title：Journal of virology

authors： Dam S,Kracht M,Pleschka S,Schmitz ML

更新日期：2016-08-12 00:00:00

abstract：:High concentrations of either trypsin or chymotrypsin caused nearly complete cleavage of capsid protein VP2 of hepatitis A virus but did not significantly reduce the infectivity, thermostability, or antigenicity of the virus. Chymotrypsin also had a lesser effect on VP1. These findings indicate the presence of a prote...

journal_title：Journal of virology

authors： Lemon SM,Amphlett E,Sangar D

更新日期：1991-10-01 00:00:00

abstract：:Amino acid analysis of [3H]proline-labeled polyomavirus major capsid protein VP1 by two-dimensional paper chromatography of the acid-hydrolyzed protein revealed the presence of 3H-labeled hydroxyproline. Addition of the proline analog L-azetidine-2-carboxylic acid to infected mouse kidney cell cultures prevented or gr...

journal_title：Journal of virology

authors： Ludlow JW,Consigli RA

更新日期：1989-06-01 00:00:00

abstract：:Endocytosis and endosomal trafficking regulate the proteins targeted to the plasma membrane and play essential roles in diverse cellular processes, including responses to pathogen attack. Here, we report the identification of Glycine max (soybean) endocytosis dynamin-like protein 5A (GmSDL5A) associated with purified ...

journal_title：Journal of virology

authors： Wu G,Cui X,Chen H,Renaud JB,Yu K,Chen X,Wang A

更新日期：2018-11-12 00:00:00

abstract：:Mutants of bacteriophage T4D that are defective in genes 42 (dCMP hydroxymethylase), 46 (DNA exonuclease), and 56 (dCTPase) produce limited amounts of phage DNA in Escherichia coli B. In this DNA, glucoylated 5-hydroxymethylcytosine is completely replaced by cytosine. We found that this DNA rapidly becomes fragmented ...

journal_title：Journal of virology

authors： Carlson K,Wiberg JS

更新日期：1983-10-01 00:00:00

abstract：:Picornaviruses rearrange cellular membranes to form cytosolic replication sites. In the case of poliovirus and several other picornaviruses, these membranes are derived from subversion of the cellular autophagy pathway. We also reported observation of autophagosome-like structures during infection by two human rhinovi...

journal_title：Journal of virology

authors： Klein KA,Jackson WT

更新日期：2011-09-01 00:00:00

abstract：:Measles virus (MeV), like all viruses of the order Mononegavirales, utilizes a complex consisting of genomic RNA, nucleoprotein, the RNA-dependent RNA polymerase, and a polymerase cofactor, the phosphoprotein (P), for transcription and replication. We previously showed that a recombinant MeV that does not express anot...

journal_title：Journal of virology

authors： Pfaller CK,Bloyet LM,Donohue RC,Huff AL,Bartemes WP,Yousaf I,Urzua E,Clavière M,Zachary M,de Masson d'Autume V,Carson S,Schieferecke AJ,Meyer AJ,Gerlier D,Cattaneo R

更新日期：2020-01-31 00:00:00

abstract：:The folded genome of Escherichia coli is converted to a slower-sedimenting form within 5 min after infection with bacteriophage T4 or T4nd28(den A)-amN82(44). Chloramphenicol sensitivity and response to UV-irradiation of the phage suggest participation of viral-induced functions. ...

journal_title：Journal of virology

authors： Tutas DJ,Wehner JM,Koerner JF

更新日期：1974-02-01 00:00:00

abstract：:Organotypic cultures support the stratification and differentiation of keratinocytes and the human papillomavirus (HPV) life cycle. We report transcription from four novel promoters in the HPV31b upstream regulatory region during the viral life cycle in organotypic cultures. Promoter initiation was not differentiation...

journal_title：Journal of virology

authors： Ozbun MA,Meyers C

更新日期：1999-04-01 00:00:00

abstract：:We have investigated the ability of human immunodeficiency virus type 1 (HIV-1) and HIV-2 isolates to infect and replicate in primary human macrophages. Monocytes from blood donors were allowed to differentiate into macrophages by culture in the presence of autologous lymphocytes and human serum for 5 days before infe...

journal_title：Journal of virology

authors： Valentin A,Albert J,Fenyö EM,Asjö B

更新日期：1994-10-01 00:00:00

abstract：:We have examined EcoRI-restricted cellular DNA from BALB/c mouse-hamster somatic cell hybrids by blot hybridization for the presence of mouse mammary tumor virus-related sequences. Results of this analysis show that mouse mammary tumor virus-related proviral copies are located on chromosomes 16 (16-kilobase-pair fragm...

journal_title：Journal of virology

authors： Callahan R,Gallahan D,Kozak C

更新日期：1984-03-01 00:00:00

abstract：:When short pulses of [(3)H]uracil were administered to Bacillus subtilis infected with phage 2C, the main species of labeled RNA was a 10S component that hybridized chiefly, but not exclusively, with the heavy strand of 2C DNA. After long pulses, most of the radioactivity was found in the 23S, 16S, and 5S rRNA's, whic...

journal_title：Journal of virology

authors： Cocito C

更新日期：1974-12-01 00:00:00

abstract：:The internal hydrophobic sequence within the flaviviral capsid protein (protein C) plays an important role in the assembly of infectious virions. Here, this sequence was analyzed in a West Nile virus lineage I isolate (crow V76/1). An infectious cDNA clone was constructed and used to introduce deletions into the inter...

journal_title：Journal of virology

authors： Schlick P,Taucher C,Schittl B,Tran JL,Kofler RM,Schueler W,von Gabain A,Meinke A,Mandl CW

更新日期：2009-06-01 00:00:00

abstract：:There are no known RNA viruses that infect Archaea. Filling this gap in our knowledge of viruses will enhance our understanding of the relationships between RNA viruses from the three domains of cellular life and, in particular, could shed light on the origin of the enormous diversity of RNA viruses infecting eukaryot...

journal_title：Journal of virology

authors： Bolduc B,Shaughnessy DP,Wolf YI,Koonin EV,Roberto FF,Young M

更新日期：2012-05-01 00:00:00

abstract：:The entire genome of the reference strain of bluetongue virus (BTV) serotype 16 (strain RSArrrr/16) was sequenced (a total of 23,518 base pairs). The virus was obtained from the Orbivirus Reference Collection (ORC) at IAH, Pirbright, United Kingdom. The virus strain, which was previously provided by the Onderstepoort ...

journal_title：Journal of virology

authors： Maan S,Maan NS,Singh KP,Belaganahalli MN,Guimera M,Pullinger G,Nomikou K,Mertens PP

更新日期：2012-09-01 00:00:00

abstract：:Viruses efficiently block the host antiviral response in order to replicate and spread before host intervention. The mechanism initiating antiviral immunity during stealth viral replication is unknown, but recent data demonstrate that defective viral genomes generated at peak virus replication are critical for this pr...

journal_title：Journal of virology

authors： López CB

更新日期：2014-08-01 00:00:00

abstract：:Murine models have suggested that CD8+ T-cell responses peak early in acute viral infections and are not sustained, but no evidence for humans has been available. To address this, we longitudinally analyzed the CD8+ T-cell response to human parvovirus B19 in acutely infected individuals. We observed striking CD8+ T-ce...

journal_title：Journal of virology

authors： Norbeck O,Isa A,Pöhlmann C,Broliden K,Kasprowicz V,Bowness P,Klenerman P,Tolfvenstam T

更新日期：2005-09-01 00:00:00

abstract：:In a previous study (S. Zheng, G. N. Woode, D. R. Melendy, and R. F. Ramig, J. Clin. Microbiol. 27:1939-1945, 1989), it was predicted that the VP7 serotype 6 bovine rotavirus strains NCDV and B641 do not share antigenically similar VP4s. In this study, gene 4 and the VP7 gene of B641 were sequenced, and the amino acid...

journal_title：Journal of virology

authors： Hardy ME,Woode GN,Xu ZC,Gorziglia M

更新日期：1991-10-01 00:00:00

abstract：:Epstein-Barr virus is associated with several human malignancies including Burkitt's lymphoma, nasopharyngeal carcinoma, and Hodgkin's disease (HD). To examine the effect of Epstein-Barr virus nuclear antigen 1 (EBNA-1) in the pathogenesis of HD, we transfected the gene into the HD cell line L428. EBNA-1 expression wa...

journal_title：Journal of virology

authors： Kube D,Vockerodt M,Weber O,Hell K,Wolf J,Haier B,Grässer FA,Müller-Lantzsch N,Kieff E,Diehl V,Tesch H

更新日期：1999-02-01 00:00:00

abstract：:The possible addition of extra sequences to simian virus 40 (SV40) DNA was analyzed by electron microscopy in two different cell systems, productively infected monkey cells and activated heterokaryons on monkey and transformed mouse 3T3 cells. We found that the closed circular DNA fraction, extracted from monkey cells...

journal_title：Journal of virology

authors： Yoshike K,Defendi V

更新日期：1977-08-01 00:00:00

abstract：:Viral manipulation of transduction pathways associated with key cellular functions such as survival, response to microbial infection, and cytoskeleton reorganization can provide the supportive milieu for a productive infection. Here, we demonstrate that vaccinia virus (VACV) infection leads to activation of the stress...

journal_title：Journal of virology

authors： Pereira AC,Leite FG,Brasil BS,Soares-Martins JA,Torres AA,Pimenta PF,Souto-Padrón T,Traktman P,Ferreira PC,Kroon EG,Bonjardim CA

更新日期：2012-01-01 00:00:00

abstract：:The adenovirus E1A 243R oncoprotein is capable of transactivating the expression of the human proliferating cell nuclear antigen (PCNA) promoter. Mutational analysis of the E1A 243R protein suggested that both its p300/CBP- and p107-binding regions are required for optimal induction of the PCNA promoter (C. Kannabiran...

journal_title：Journal of virology

authors： Lee BH,Liu M,Mathews MB

更新日期：1998-02-01 00:00:00